Analysis of Myocardial (18)F-FDG Uptake by PET/CT in the Patients with Different Dialectically Classified Coronary Heart Diseases (CHD).

Abstract:

:To quantify myocardial glucose metabolism by (18)F-FDG PET/CT in patients that have coronary heart disease (CHD) according to traditional Chinese medicine classification. Ninety patients with CHD were enrolled and were categorized into three groups. All patients underwent PET-CT examination for (18)F-FDG uptake quantification. In group A, the radioactive signals were weak in multiple segments in 27 cases (90 %). One case had no visualization and two had normal visualization (mean SUV = 4 ± 0.6). In group B, the radioactive signals were in some local areas in eight cases (26.7 %). Twenty cases had an overall increase in signal density (SUV ≥ 8) (66.7 %). One case had no visualization, and one case had normal visualization (mean SUV 4 ± 0.6). In group C, 23 cases had no visual or a weak visual (SUV ≤ 2 ± 0.3) (76.7 %). Seven cases had segmental weak signals or signal defects. Different types of CHD demonstrate different metabolisms of myocardium glucose. It is necessary to dialectically classify CHD and apply differential treatment.

journal_name

Cell Biochem Biophys

authors

Tan YY,Liu DF,Zhu F,Ding XM,Wang GM

doi

10.1007/s12013-015-0538-3

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

813-6

issue

3

eissn

1085-9195

issn

1559-0283

pii

10.1007/s12013-015-0538-3

journal_volume

72

pub_type

杂志文章
  • Determination of enantiomeric impurity of levamlodipine besylate bulk drug by capillary electrophoresis using carboxymethyl-β-cyclodextrin.

    abstract::A rapid capillary electrophoresis method using carboxymethyl-β-cyclodextrin (CM-β-CD) as chiral selector was developed and validated for the enantiomeric purity determination of levamlodipine besylate bulk drug. Several parameters for were optimized for a satisfactory enantioresolution, including pH of background elec...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0106-2

    authors: Qi Y,Zhang X

    更新日期:2014-12-01 00:00:00

  • Studies on the expression patterns of class I PI3K catalytic subunits and its prognostic significance in colorectal cancer.

    abstract::The phosphatidylinositol 3-kinase/AKT (PI3K/AKT) pathway plays a critical role in human cancer. We determined the expression patterns of class I PI3K catalytic subunits and evaluated their importance in the development or progression of colorectal cancer (CRC). For this purpose, expression of class I PI3K isoforms was...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-011-9257-6

    authors: Cui B,Tao J,Yang Y

    更新日期:2012-01-01 00:00:00

  • Determination of concentration of methotrexate enantiomers in intracellular and extracellular fluids of HepG2 cells by liquid chromatography-tandem mass spectrometry.

    abstract::A rapid and sensitive liquid chromatography-tandem mass spectrometry assay (LC-MS/MS) with electrospray ionization was developed and validated for the quantitative determination of the concentration of methotrexate (MTX) enantiomers in intracellular and extracellular fluids of HepG2 cells. The analytes were extracted ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9666-9

    authors: Wang R,Guo L,Xie H,Zhang J,Li X,Li W,Wang J,Wu X,Jia Z

    更新日期:2013-01-01 00:00:00

  • A Simple Analytical Approximation to an Inhomogeneously-Broadened Dispersion Spectrum. Application to Absorption-Dispersion Admixtures.

    abstract::A simple analytical approximation to an inhomogeneously-broadened dispersion signal is proposed and tested with resonance lines broadened by unresolved hyperfine structure. Spectral parameters may be rapidly and accurately extracted using a nonlinear least-squares fitting algorithm. Combining the new approximation to ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-016-0760-7

    authors: Bales BL

    更新日期:2017-06-01 00:00:00

  • Inactivation of calcium channels in vascular smooth muscle myocytes.

    abstract::Many of the structural domains involved in Ca2+ channel (CACN) inactivation are also involved in determining their sensitivity to antagonist inhibition. We hypothesize that differences in inactivation properties and their structural determinants may suggest candidate domains as targets for the development of novel, se...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/CBB:45:3:229

    authors: Cox RH,Kathrins M

    更新日期:2006-01-01 00:00:00

  • A pH dependence study on the unfolding and refolding of apoazurin: comparison with Zn(II) azurin.

    abstract::Azurin, a small blue copper protein from the bacterial species Pseudomonas aeruginosa, is mostly a beta-sheet protein arranged into a single domain. Previous folding studies have shown that the equilibrium denaturation of the holoprotein follows a two-state process; however, upon removal of the copper, the denaturatio...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/cbb:36:1:19

    authors: Hansen JE,McBrayer MK,Robbins M,Suh Y

    更新日期:2002-01-01 00:00:00

  • Spectral CT imaging in patients with Budd-Chiari syndrome: investigation of image quality.

    abstract::To assess the image quality of monochromatic imaging from spectral CT in patients with Budd-Chiari syndrome (BCS), fifty patients with BCS underwent spectral CT to generate conventional 140 kVp polychromatic images (group A) and monochromatic images, with energy levels from 40 to 80, 40 + 70, and 50 + 70 keV fusion im...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0021-6

    authors: Su L,Dong J,Sun Q,Liu J,Lv P,Hu L,Yan L,Gao J

    更新日期:2014-11-01 00:00:00

  • Correlation of matrix metalloproteinases-1 and tissue inhibitor of metalloproteinases-1 with patient age and grade of lumbar disk herniation.

    abstract::The authors studied the nuclear magnetic resonance films and the expression of MMP-1 and TIMP-1 in disk specimens' of patients who had undergone operations for lumbar disk herniation. Forty-one lumbar disk patients were evaluated imaging for degenerative changes and their disk specimens immunohistochemical expression ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-9815-9

    authors: Xu H,Mei Q,He J,Liu G,Zhao J,Xu B

    更新日期:2014-07-01 00:00:00

  • Applicability of different endovascular methods for treatment of refractory Budd-Chiari syndrome.

    abstract::The study's objective was to evaluate the applicability of different endovascular methods for treatment of refractory type of Budd-Chiari syndrome (BCS) under specific scenarios frequently encountered in patients. The treatment methods were evaluated in 197 patients with the following four types of refractory BCS: les...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-011-9211-7

    authors: Gao Y,Chen S,Yu C

    更新日期:2011-11-01 00:00:00

  • On the Regularities of the Polar Profiles of Proteins Related to Ebola Virus Infection and their Functional Domains.

    abstract::The number of fatalities and economic losses caused by the Ebola virus infection across the planet culminated in the havoc that occurred between August and November 2014. However, little is known about the molecular protein profile of this devastating virus. This work represents a thorough bioinformatics analysis of t...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-018-0839-4

    authors: Polanco C,Samaniego Mendoza JL,Buhse T,Uversky VN,Bañuelos Chao IP,Bañuelos Cedano MA,Tavera FM,Tavera DM,Falconi M,Ponce de León AV

    更新日期:2018-09-01 00:00:00

  • Molecular mechanisms by which saturated fatty acids modulate TNF-α expression in mouse macrophage lineage.

    abstract::Many macrophage functions are modulated by fatty acids (FAs), including cytokine release, such as tumor necrosis factor-α (TNF-α). TNF-α is of great interest due to its role in the inflammation process observed in several diseases such as rheumatoid arthritis, atherosclerosis, and obesity. However, the mechanisms by w...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-010-9117-9

    authors: de Lima-Salgado TM,Alba-Loureiro TC,do Nascimento CS,Nunes MT,Curi R

    更新日期:2011-03-01 00:00:00

  • Effects of tumor necrosis factor inhibitor on serum level of HLA-B27 and PDCD-1 in patients with ankylosing spondylitis.

    abstract::The aim of this study was to evaluate the effect of tumor necrosis factor-alpha (TNF-α) inhibitor-infliximab on ankylosing spondylitis (AS) patients and detect the serum level of HLA-B27 and PDCD-1 before and after TNF inhibitor treatment. 138 patients at active stage of AS were treated with infliximab; serum was coll...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0082-6

    authors: Chen X,Zhou X,Li X,Tang J,Hu X,Wang J,Xu C

    更新日期:2014-11-01 00:00:00

  • (Pro)Insulin processing: a historical perspective.

    abstract::Insulin, the major secreted product of the beta-cells of the islets of Langerhans, is initially synthesized as a precursor (preproinsulin), from which the mature hormone is excised by a series of proteolytic cleavages. This review provides a personal narrative of some of the key research projects leading to the identi...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1385/cbb:40:3:143

    authors: Davidson HW

    更新日期:2004-01-01 00:00:00

  • Novel c.2216T > C (p.I739T) mutation in exon 13 and c.1481T > A (p.L494X) mutation in exon 8 of MUT gene in a female with methylmalonic acidemia.

    abstract::We report herein a 1.5-year-old girl with methylmalonic acidemia (MMA) in whom two missense mutations were found: a novel I739T mutation located in exon 13 and the L494X mutation in exon 8. The results of organic acid test showed a pronounced increase in methylmalonate excretion with increased methylcitrate and 3-OH-p...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9532-9

    authors: Imataka G,Sakamoto O,Yamanouchi H,Yoshihara S,Omura-Hasegawa Y,Tajima G,Arisaka O

    更新日期:2013-09-01 00:00:00

  • Influence of magnetic field on brain activity during administration of caffeine.

    abstract::The aim of the present work is to evaluate the effect of caffeine, the world's most popular psychoactive drug, on the electric activity of the rat's brain that exposed to extremely low-frequency magnetic field (ELF-MF), during 15 days. The obtained results showed that administration of caffeine in a group of rats by d...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9584-x

    authors: El Gohary MI,Salama AA,El Saeid AA,El Sayed TM,Kotb HSh

    更新日期:2013-01-01 00:00:00

  • Topoisomerase IIalpha mediates E2F-1-induced chemosensitivity and is a target for p53-mediated transcriptional repression.

    abstract::Mutations of the retinoblastoma tumor suppressor, pRb, or its cyclin-cyclin-dependent kinase (CDK) regulatory kinases or CDK inhibitors, allows unrestrained E2F activity, leading to unregulated cell cycle progression. However, overexpression of E2F-1 also sensitizes cells to apoptosis, suggesting that targeting this p...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/CBB:33:2:199

    authors: Nip J,Hiebert SW

    更新日期:2000-01-01 00:00:00

  • Influence of amino acids Shiff bases on irradiated DNA stability in vivo.

    abstract::To reveal protective role of the new Mn(II) complexes with Nicotinyl-L-Tyrosinate and Nicotinyl-L-Tryptophanate Schiff Bases against ionizing radiation. The DNA of the rats liver was isolated on 7, 14, and 30 days after X-ray irradiation. The differences between the DNA of irradiated rats and rats pre-treated with Mn(...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9617-5

    authors: Karapetyan NH,Malakyan MH,Bajinyan SA,Torosyan AL,Grigoryan IE,Haroutiunian SG

    更新日期:2013-01-01 00:00:00

  • Regulation of steroid receptor subcellular trafficking.

    abstract::Cellular responses to external signals often reflect alterations in gene expression. The activation of cell surface hormone or growth factor receptors upon the binding of appropriate ligands mobilizes signal transduction cascades that can ultimately impact the activity of defined sets of transcription factors. The int...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02737882

    authors: DeFranco DB

    更新日期:1999-01-01 00:00:00

  • Highly Conserved Arg Residue of ERFNIN Motif of Pro-Domain is Important for pH-Induced Zymogen Activation Process in Cysteine Cathepsins K and L.

    abstract::Pro-domain of a cysteine cathepsin contains a highly conserved Ex2Rx2Fx2Nx3Ix3N (ERFNIN) motif. The zymogen structure of cathepsins revealed that the Arg(R) residue of the motif is a central residue of a salt-bridge/H-bond network, stabilizing the scaffold of the pro-domain. Importance of the arginine is also demonstr...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-017-0838-x

    authors: Aich P,Biswas S

    更新日期:2018-06-01 00:00:00

  • VEGFR, RET, and RAF/MEK/ERK pathway take part in the inhibition of osteosarcoma MG63 cells with sorafenib treatment.

    abstract::Osteosarcoma (OS) is the leading primary malignant bone tumor in children and young adults. It is response for a high mortality rate. Nowadays, few researches have been performed on sorafenib against OS and no tools are available to guide the use of sorafenib in the OS treatment. In this study, we aim to investigate t...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9781-7

    authors: Mei J,Zhu X,Wang Z,Wang Z

    更新日期:2014-05-01 00:00:00

  • Curcumin Mediates a Protective Effect Via TLR-4/NF-κB Signaling Pathway in Rat Model of Severe Acute Pancreatitis.

    abstract::Severe acute pancreatitis (SAP) is a common acute abdominal disease. This study was designed to investigate the preventive effects of curcumin on SAP and its possible mechanism of action. We observed increased volume of ascites, serum AMY, IL-6, and TNF-α levels, and expression of TLR-4 and NF-κB mRNA and protein in a...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-015-0664-y

    authors: Zhong K

    更新日期:2015-09-01 00:00:00

  • The effects and mechanism of miR-92a and miR-126 on myocardial apoptosis in mouse ischemia-reperfusion model.

    abstract::Our objective was to explore the effects of miR-92a and miR-126 on myocardial apoptosis in mouse ischemia-reperfusion model and further investigate the underlying mechanisms. Eighteen Kunming mice were selected and randomly divided into sham operation group and ischemia-reperfusion group with nine mice in each group. ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0149-4

    authors: Jiang C,Ji N,Luo G,Ni S,Zong J,Chen Z,Bao D,Gong X,Fu T

    更新日期:2014-12-01 00:00:00

  • Advantages, Disadvantages, and Trend of Integrative Medicine in the Treatment of Heart Failure.

    abstract::Integrative medicine therapy using traditional Chinese medicine (TCM) combined with western medicine has shown some advantages in treating heart failure (HF), such as holistic concept; multi-target treatment; dialectical logic; personalized therapy; formulae compatibility; and reduction of side effects of western medi...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s12013-014-0466-7

    authors: Zhang P

    更新日期:2015-06-01 00:00:00

  • Study of the mechanism of bystander effect of KDR-CDglyTK system mediated by adenovirus for the treatment of gastric cancer.

    abstract::We evaluated the relationship between cellular gap junction and bystander effect in gastric cancer SCG7901 cell killing by adenovirus-mediated KDR-CDglyTK system. SCG7901 and HeLa cells were transfected (MOI-100) with recombinant adenovirus carrying fusion gene. Transfection efficiency/fusion gene mRNA expression were...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9599-3

    authors: Qiang L,Yanping L,Zonghai H,Fei C,Zhou L,Jinlong Y

    更新日期:2013-01-01 00:00:00

  • Modulation of ion channel function by P2Y receptors.

    abstract::P2Y receptors are classified as P2 purinergic receptors that belong to the superfamily of G-protein coupled receptors. They are distinguishable from P1 (adenosine) receptors in that they bind adenine and/or uracil nucleotide triphosphates or diphosphates depending on the subtype. Over the past decade, P2Y receptors ha...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1385/CBB:39:1:75

    authors: Lee SY,O'Grady SM

    更新日期:2003-01-01 00:00:00

  • Cell contraction caused by microtubule disruption is accompanied by shape changes and an increased elasticity measured by scanning acoustic microscopy.

    abstract::The state of crosslinking of microfilaments and the state of myosin-driven contraction are the main determinants of the mechanical properties of the cell cortex underneath the membrane, which is significant for the mechanism of shaping cells. Therefore, any change in the contractile state of the actomyosin network wou...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/BF02737896

    authors: Karl I,Bereiter-Hahn J

    更新日期:1998-01-01 00:00:00

  • Measuring activity in the ubiquitin-proteasome system: from large scale discoveries to single cells analysis.

    abstract::The ubiquitin-proteasome system (UPS) is the primary pathway responsible for the recognition and degradation of misfolded, damaged, or tightly regulated proteins in addition to performing essential roles in DNA repair, cell cycle regulation, cell migration, and the immune response. While traditional biochemical techni...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s12013-013-9621-9

    authors: Melvin AT,Woss GS,Park JH,Waters ML,Allbritton NL

    更新日期:2013-09-01 00:00:00

  • Association of hematocrit and pre-hypertension among Chinese adults: the CRC study.

    abstract::Elevated blood pressure is regarded as an independent risk factor for cardiovascular diseases and diabetes. We examined the relation between hematocrit and pre-hypertension as well as the effect of sex, obesity, fasting glucose, and lipids in Chinese adults. The study samples were from a community-based health examina...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0318-5

    authors: Liu X,Liang J,Qiu Q,Zhu Y,Sun Y,Ying P,Teng F,Wang Y,Qi L

    更新日期:2015-03-01 00:00:00

  • Impact analysis of autoantibody level and NR2 antibody level in neuropsychiatric SLE treated by methylprednisolone combined with MTX and DXM intrathecal injection.

    abstract::The objective is to explore the clinical curative effects of methylprednisolone combined with MTX and DXM intrathecal injection in treating neuropsychiatric systemic lupus erythematosus (NPSLE) and its effects on autoantibody level and anti-N-methyl-D-aspartate receptor subtype NR2a/2b antibody (anti-NR2 antibody) lev...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0010-9

    authors: Wang J,Zhao Y,Zhang J,Lei H,Zhu G,Fu B

    更新日期:2014-11-01 00:00:00

  • Mutations in microRNA binding sites of CEP genes involved in cancer.

    abstract::The CEP genes play a pivotal role in the replication of the cell. CEP family proteins form the major constituents of the centrosome and play a prominent role in centriole biogenesis and in cell replication. Alteration in CEP genes will result in disruption of cell cycle that may in turn cause cancer. In our study, we ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0153-8

    authors: Gopalakrishnan C,Kamaraj B,Purohit R

    更新日期:2014-12-01 00:00:00