Synergistic effect of phenformin in non-small cell lung cancer (NSCLC) ionizing radiation treatment.

abstract：:Recent studies designed to assess the relationship between aortic compliance and heterogeneity of heart electrical activity has shown that hypertrophy aggravates repolarization disturbances in the myocardium. Numerous mechanisms of electrical instability and inhomogeneity associated with left ventricular hypertrophy a...

journal_title：Cell biochemistry and biophysics

authors： Gao C,Yang D

更新日期：2014-07-01 00:00:00

abstract：:Azurin, a small blue copper protein from the bacterial species Pseudomonas aeruginosa, is mostly a beta-sheet protein arranged into a single domain. Previous folding studies have shown that the equilibrium denaturation of the holoprotein follows a two-state process; however, upon removal of the copper, the denaturatio...

journal_title：Cell biochemistry and biophysics

authors： Hansen JE,McBrayer MK,Robbins M,Suh Y

更新日期：2002-01-01 00:00:00

abstract：:To explore the proteomic changes of placental trophoblastic cells in preeclampsia-eclampsia (PE), placental trophoblastic cells from normally pregnant women and women with hypertension during gestational period were prepared by laser capture microdissection (LCM), and proteins isolated from these cells were subjected ...

journal_title：Cell biochemistry and biophysics

authors： Ma K,Jin H,Hu R,Xiong Y,Zhou S,Ting P,Cheng Y,Yang Y,Yang P,Li X

更新日期：2014-06-01 00:00:00

abstract：:The aim is to study the anticancer effect of CXCR4 gene knockdown by CXCR4-siRNA in nude mice model of ovarian cancer. Injecti the SW626 tumor cells which had been transfected by vectors to make nude mouse model of ovarian cancer. The model mice were divided into interference group, negative control group, and blank c...

journal_title：Cell biochemistry and biophysics

authors： Liu W,Wang Y,Wang H,Wang A

更新日期：2014-12-01 00:00:00

abstract：:Topical application of 10-hydroxycamptothecin (HCPT) can reduce intra-articular scar adhesion after knee surgery, but the effect of HCPT on wound healing has not yet been elucidated. The study investigates the effect of the topical application of HCPT on wound healing after knee surgery in rabbits. Forty New Zealand w...

journal_title：Cell biochemistry and biophysics

authors： Yan L,Sun Y,Li X,Liang Y,Zhu G,Wang J,Xiao T

更新日期：2015-09-01 00:00:00

abstract：:Several single nucleotide polymorphisms (SNPs) within the CTLA-4 gene and elevated serum levels of soluble CTLA-4 (sCTLA-4) have been associated with autoimmunity including rheumatoid arthritis (RA). In this case-control study, we evaluated the relationship between the -319C/T (rs5742909) and CT60 G/A (rs3087243) SNPs...

journal_title：Cell biochemistry and biophysics

authors： Torres-Carrillo N,Ontiveros-Mercado H,Torres-Carrillo NM,Parra-Rojas I,Rangel-Villalobos H,Ramírez-Dueñas MG,Gutiérrez-Ureña SR,Valle Y,Muñoz-Valle JF

更新日期：2013-01-01 00:00:00

abstract：:The aim of the study was to investigate changes in the plasma antioxidative activity and in lipid peroxidation after administration of endothelin-1 (ET-1) and endothelin receptor blockers and additionally, to estimate blood pressure. The study was performed on male Wistar rats (n = 6 per group) divided into 4 groups w...

journal_title：Cell biochemistry and biophysics

authors： Kleniewska P,Kowalczyk A,Ciesla W,Goraca A

更新日期：2015-04-01 00:00:00

abstract：:The objective of this study was to assess the clinical and histopathological relationship between pulmonary fibrosis and type 1 diabetes. We examined clinical pulmonary function parameters and transbronchial lung biopsies to assess associated histopathological changes in 12 type 1 diabetic patients presenting with dys...

journal_title：Cell biochemistry and biophysics

authors： Hu Y,Ma Z,Guo Z,Zhao F,Wang Y,Cai L,Yang J

更新日期：2014-11-01 00:00:00

abstract：:A new intraoperative cisplatin administration method for patients with locally advanced gastric cancer (AGC) and without peritoneal metastasis, fibrin-sealant-delivered cisplatin chemotherapy, was reported, and its safety, pharmacokinetics, and efficacy were compared with cisplatin hyperthermic intraperitoneal perfusi...

journal_title：Cell biochemistry and biophysics

authors： Huang O,Lu X,Xu X,Shi Y

更新日期：2015-03-01 00:00:00

abstract：:The divergence of protein (Hedgehog) in different organisms remains an unresolved issue to comprehend how the pathway in Hh signaling evolves. Insights into this question can help one identify the key molecules in Hh signaling. This work proposes a protein-associated factor in cells. The development of a non-reduction...

journal_title：Cell biochemistry and biophysics

authors： Sarker MM,Zhou MC,Rameshwar P,Hanover JA

更新日期：2014-04-01 00:00:00

abstract：:Mechanics of cancer cells are directly linked to their metastatic potential, or ability to produce a secondary tumor at a distant site. Metastatic cells survive in the circulatory system in a non-adherent state, and can squeeze through barriers in the body. Such considerable structural changes in cells rely on rapid r...

journal_title：Cell biochemistry and biophysics

authors： Gal N,Weihs D

更新日期：2012-07-01 00:00:00

abstract：:MicroRNAs (miRs) play important roles in initiation and progression of many pathologic processes. However, the roles of miRs in diabetic nephropathy remain unclear. This study was to determine whether miR-21 was involved in diabetic nephropathy and to explore the relationship between miR-21 and MMP9/TIMP1 expression i...

journal_title：Cell biochemistry and biophysics

authors： Wang J,Gao Y,Ma M,Li M,Zou D,Yang J,Zhu Z,Zhao X

更新日期：2013-11-01 00:00:00

abstract：:Cell membranes consist of a fluidic medium of lipids and proteins that organize into specific submicron scale structures for signaling and molecular trafficking processes. These organized molecular assemblies form as a result of the structure and chemistry of the membrane components as well as the interactions of thos...

journal_title：Cell biochemistry and biophysics

authors： Sasaki DY

更新日期：2003-01-01 00:00:00

abstract：:cDNAs encoding two PDE-3 or cyclic GMP-inhibited (cGI) cyclic nucleotide phosphodiesterase (PDE) isoforms, RPDE-3B (RcGIP1) and HPDE-3A (HcGIP2), were cloned from rat (R) adipose tissue and human (H) heart cDNA libraries. Deletion and N- and C-terminal truncation mutants were expressed in Escherichia coli in order to ...

journal_title：Cell biochemistry and biophysics

authors： He R,Komas N,Ekholm D,Murata T,Taira M,Hockman S,Degerman E,Manganiello VC

更新日期：1998-01-01 00:00:00

abstract：:The umami taste receptor is a heterodimer composed of two members of the T1R taste receptor family: T1R1 and T1R3. The homology models of the ligand binding domains of the human umami receptor have been constructed based on crystallographic structures of the taste receptor of the central nervous system. Furthermore, t...

journal_title：Cell biochemistry and biophysics

authors： Dang Y,Gao X,Xie A,Wu X,Ma F

更新日期：2014-12-01 00:00:00

abstract：:A Caulimovirus-based hybrid-promoter, EFCFS, was derived by fusing the distal region (-227 to -54, FUAS) of Figwort mosaic virus full-length transcript promoter (F20) with the core promoter (-151 to +12, FS3CP) domain of Figwort mosaic virus sub-genomic transcript promoter (FS3). The hybrid-promoter (EFCFS) showed enh...

journal_title：Cell biochemistry and biophysics

authors： Ranjan R,Dey N

更新日期：2012-07-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) has been known to enhance the growth of normal hepatocytes, but also to inhibit the growth of neoplastic cells. This article examines the involvement of HGF in the hepatocarcinogenesis caused by peroxisome proliferators (PPs). Up to 78 wk after male F-344 rats were orally given (4-chloro...

journal_title：Cell biochemistry and biophysics

authors： Suga T,Motoki Y,Tamura H,Watanabe T

更新日期：2000-01-01 00:00:00

abstract：:Integrative medicine therapy using traditional Chinese medicine (TCM) combined with western medicine has shown some advantages in treating heart failure (HF), such as holistic concept; multi-target treatment; dialectical logic; personalized therapy; formulae compatibility; and reduction of side effects of western medi...

journal_title：Cell biochemistry and biophysics

authors： Zhang P

更新日期：2015-06-01 00:00:00

abstract：:It has been long known that the oncogenic extracellular environment plays an indispensable role in developing and nurturing cancer cell progression and in resistance to standard treatments. However, by how much the biophysical components of tumour extracellular environment contribute to these processes is uncertain. I...

journal_title：Cell biochemistry and biophysics

authors： Sarwar M,Sykes PH,Chitcholtan K,Evans JJ

更新日期：2021-01-12 00:00:00

abstract：:The aim of the present work is to evaluate the effect of caffeine, the world's most popular psychoactive drug, on the electric activity of the rat's brain that exposed to extremely low-frequency magnetic field (ELF-MF), during 15 days. The obtained results showed that administration of caffeine in a group of rats by d...

journal_title：Cell biochemistry and biophysics

authors： El Gohary MI,Salama AA,El Saeid AA,El Sayed TM,Kotb HSh

更新日期：2013-01-01 00:00:00

abstract：:We have studied the mechanisms of NaCl transport in the mammalian proximal tubule. Studies of isolated brush-border membrane vesicles confirmed the presence of Na+-H+ exchange and identified Cl(-)-formate and Cl(-)-oxalate exchangers as possible mechanisms of uphill Cl- entry. We found that formate and oxalate each st...

journal_title：Cell biochemistry and biophysics

authors： Aronson PS

更新日期：2002-01-01 00:00:00

abstract：:Many macrophage functions are modulated by fatty acids (FAs), including cytokine release, such as tumor necrosis factor-α (TNF-α). TNF-α is of great interest due to its role in the inflammation process observed in several diseases such as rheumatoid arthritis, atherosclerosis, and obesity. However, the mechanisms by w...

journal_title：Cell biochemistry and biophysics

authors： de Lima-Salgado TM,Alba-Loureiro TC,do Nascimento CS,Nunes MT,Curi R

更新日期：2011-03-01 00:00:00

abstract：:The objective of this study is to observe the adult growth hormone level in postoperative pituitary tumor patients of multi-centers, and explore the change of hypophyseal hormones in postoperative pituitary tumor patients. Sixty patients with pituitary tumor admitted during March, 2011-March, 2012 were selected. Posto...

journal_title：Cell biochemistry and biophysics

authors： Cheng JM,Gu JW,Kuang YQ,Ma Y,Xia X,Yang T,Lu M,He WQ,Sun ZY,Zhang YC

更新日期：2015-03-01 00:00:00

abstract：:The ubiquitin-proteasome system (UPS) is the primary pathway responsible for the recognition and degradation of misfolded, damaged, or tightly regulated proteins in addition to performing essential roles in DNA repair, cell cycle regulation, cell migration, and the immune response. While traditional biochemical techni...

journal_title：Cell biochemistry and biophysics

authors： Melvin AT,Woss GS,Park JH,Waters ML,Allbritton NL

更新日期：2013-09-01 00:00:00

abstract：:STAT3 pathway plays an important role in the growth of diffuse large B-cell lymphoma (DLBCL) cells. Here we investigated the antitumor activity of Quercetin, a flavonoid compound, in combination with rituximab in DLBCL cell lines in vitro. We found that Quercetin synergistically enhanced rituximab-induced growth inhib...

journal_title：Cell biochemistry and biophysics

authors： Li X,Wang X,Zhang M,Li A,Sun Z,Yu Q

更新日期：2014-11-01 00:00:00

abstract：:Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) is a cellular receptor for hepatitis C virus for the binding of viral envelope glycoprotein E2. Interaction of DC-SIGN with the E2 may evoke cellular signal transduction implicated in viral pathogenesis. We developed a cell model ...

journal_title：Cell biochemistry and biophysics

authors： Chen QL,Zhu SY,Bian ZQ,Zhao LJ,Cao J,Pan W,Qi ZT

更新日期：2010-01-01 00:00:00

abstract：:Although As2O3 (ATO) has been recommended as the front-line agent for treatment of acute promyelocytic leukemia (APL), particularly for relapsed or refractory APL, it has been associated with profound toxicity. Icariin is a natural compound with activity against a variety of cancers. This study was designed to investi...

journal_title：Cell biochemistry and biophysics

authors： Wang Z,Zhang H,Dai L,Song T,Li P,Liu Y,Wang L

更新日期：2015-09-01 00:00:00

abstract：:Rotaviruses are one of the worldwide leading causes of gastroenteritis in children under 5 yr old. The rotavirus nonstructural NSP5 is a phosphoprotein implicated in viroplasms formation, whereas NSP6 could have a possible regulatory role of NSP5. It has been reported that N- and C-termini of NSP5 are important for th...

journal_title：Cell biochemistry and biophysics

authors： Samaniego-Hernández M,De León-Rodriguez A,Aparicio-Fabre R,Arias-Ortiz C,Barba de la Rosa AP

更新日期：2006-01-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, has been associated with the development of Kaposi's sarcoma, pleural effusion lymphoma, and multicentric Castleman's disease. KSHV is a double-stranded DNA virus that has been classified as a gammaherpesvirus. The viral genome is appro...

journal_title：Cell biochemistry and biophysics

authors： Damania B

更新日期：2004-01-01 00:00:00

abstract：:In the present study, the changes of the regulatory T cells (Treg) expression, endotoxin translocation, and the relationships in intestinal lymph nodes were investigated in porcine sepsis induced by severe burns. Flow cytometry, western blot, and Tachypleus amebocyte lysate were applied to study after the burn injury ...

journal_title：Cell biochemistry and biophysics

authors： Zu H,Li Q,Huang P

更新日期：2014-12-01 00:00:00