Functions and roles of a protein-associated factor.

Abstract:

:The divergence of protein (Hedgehog) in different organisms remains an unresolved issue to comprehend how the pathway in Hh signaling evolves. Insights into this question can help one identify the key molecules in Hh signaling. This work proposes a protein-associated factor in cells. The development of a non-reductionist theory of cellular functions in medicine is not sufficient. It is necessary to find the parameters with regards to molecules/genes that can elicit functions. This work shows that molecular interactions of gene products can be accomplished by biophysics logic. Defining the protein-associated factors in molecular activities and identifying its roles in molecular transduction are important. A misregulation in molecular switch can account for complex biomolecular consequences. This work shows the potential of the factor on homo-sapiens and unlocks its implications to gene multi-tasking functionality. The associated factor notion should facilitate the medical development in cancer therapeutics.

journal_name

Cell Biochem Biophys

authors

Sarker MM,Zhou MC,Rameshwar P,Hanover JA

doi

10.1007/s12013-013-9743-0

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

577-82

issue

3

eissn

1085-9195

issn

1559-0283

journal_volume

68

pub_type

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