Influence of magnetic field on brain activity during administration of caffeine.


:The aim of the present work is to evaluate the effect of caffeine, the world's most popular psychoactive drug, on the electric activity of the rat's brain that exposed to extremely low-frequency magnetic field (ELF-MF), during 15 days. The obtained results showed that administration of caffeine in a group of rats by dose of 10 mg/kg (equivalent to human daily consumption) caused a reduction in the mean power amplitude of electroencephalogram (EEG) trace for almost all frequency bands especially α (8-12 Hz). It was observed that the influence of caffeine was more evident in motor cortex than in visual cortex. While the exposure of another group to ELF-MF of intensity 0.2 mT during the same period caused an enhancement in the mean power amplitude of most EEG frequency bands; this was more observed in the right hemisphere of the brain than that of the left hemisphere. The administration of caffeine while rats were exposed to ELF-MF, led, after 5 days of exposure, to a great increase in the mean power amplitude of α band at all places of recording electrodes. It may be concluded that caffeine administration was more effective in reducing the hazardous of ELF-MF in motor cortex than in visual cortex.


Cell Biochem Biophys


El Gohary MI,Salama AA,El Saeid AA,El Sayed TM,Kotb HSh




Has Abstract


2013-01-01 00:00:00












  • Comparative evaluation of two laparoscopic procedures for treating common bile duct stones.

    abstract::Cholesystolithiasis is often associated with common bile duct stones (CBDS). In order to assess the choice of surgery in terms of effectiveness and complications in the treatment of CBDS, we have compared three surgical procedures, viz., laparoscopic choledocholithotomy T-tube drainage (LCH-TD), laparoscopic cholecyst...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Gu AD,Li XN,Guo KX,Ma ZT

    更新日期:2011-04-01 00:00:00

  • Azithromycin attenuates fibroblast growth factors induced vascular endothelial growth factor via p38(MAPK) signaling in human airway smooth muscle cells.

    abstract::The airways in asthma and COPD are characterized by an increase in airway smooth muscle (ASM) mass and bronchial vascular changes associated with increased expression of pro-angiogenic growth factors, such as fibroblast growth factors (FGF-1 and FGF-2) and vascular endothelial growth factor (VEGF). We investigated the...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Willems-Widyastuti A,Vanaudenaerde BM,Vos R,Dilisen E,Verleden SE,De Vleeschauwer SI,Vaneylen A,Mooi WJ,de Boer WI,Sharma HS,Verleden GM

    更新日期:2013-11-01 00:00:00

  • VEGFR, RET, and RAF/MEK/ERK pathway take part in the inhibition of osteosarcoma MG63 cells with sorafenib treatment.

    abstract::Osteosarcoma (OS) is the leading primary malignant bone tumor in children and young adults. It is response for a high mortality rate. Nowadays, few researches have been performed on sorafenib against OS and no tools are available to guide the use of sorafenib in the OS treatment. In this study, we aim to investigate t...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Mei J,Zhu X,Wang Z,Wang Z

    更新日期:2014-05-01 00:00:00

  • Toward mechanical manipulations of cell membranes and membrane proteins using an atomic force microscope: an invited review.

    abstract::Recent advances in the use of the atomic force microscope (AFM) for manipulating cell membranes and membrane proteins are reviewed. Early pioneering work on measurements of the magnitude of the force required to create indentations with defined depth on their surfaces and to separate interacting pairs of avidin-biotin...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Ikai A,Afrin R

    更新日期:2003-01-01 00:00:00

  • Synthetic miR-145 Mimic Enhances the Cytotoxic Effect of the Antiangiogenic Drug Sunitinib in Glioblastoma.

    abstract::Although aggressive therapeutic regimen has been applied in the treatment of Glioblastoma (GBM), the prognosis of patients with GBM remains poor. Preclinical studies have demonstrated the efficacy of Suntinib in GBM both in vitro and in vivo. In this study, we showed that the cytotoxicity was enhanced by transfection ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Liu H,Liu Z,Jiang B,Huo L,Liu J,Lu J

    更新日期:2015-06-01 00:00:00

  • The Inhibiting Effect of Dinitrosyl Iron Complexes with Thiol-containing Ligands on the Growth of Endometrioid Tumours in Rats with Experimental Endometriosis.

    abstract::The possibility that binuclear dinitrosyl iron complexes with glutathione and cysteine (DNIC-GSН and B-DNIC-Cys) have a strong cytotoxic effect on the growth of endometrioid tumours (EMT) in rats with surgically induced experimental endometriosis established in our previous studies has been supported with experimental...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Burgovа EN,Khristidis YI,Kurkov AV,Mikoyan VD,Shekhter AB,Adamyan LV,Timashev PS,Vanin AF

    更新日期:2019-03-01 00:00:00

  • Environmental response of yeast peroxisomes. Aspects of organelle assembly and degradation.

    abstract::Nutritional changes can affect either the assembly or disassembly of yeast peroxisomes. In the past decade, insights regarding the molecular mechanisms of peroxisome assembly have been gained chiefly through the cloning of the PEX genes obtained by complementation of corresponding pex mutants in several yeast strains ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Sakai Y,Subramani S

    更新日期:2000-01-01 00:00:00

  • Evaluation of global longitudinal strain of left ventricle and regional longitudinal strain in the region of left ventricular leads predicts the response to cardiac resynchronization therapy in patients with ischemic heart failure.

    abstract::Myocardium viability in ischemic heart failure (HF) may affect the effect of cardiac resynchronization therapy (CRT). We hypothesized that longitudinal strain of 2D-STE, which reflects myocardium viability, can predict the response to CRT in patients with ischemic HF. 2D-STE was performed in 42 patients with HF, 1 wee...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Ma CY,Liu S,Yang J,Tang L,Zhang LM,Li N,Yu B

    更新日期:2014-09-01 00:00:00

  • Insulin signaling and glucose transport in insulin resistant human skeletal muscle.

    abstract::Insulin increases glucose uptake and metabolism in skeletal muscle by signal transduction via protein phosphorylation cascades. Insulin action on signal transduction is impaired in skeletal muscle from Type 2 diabetic subjects, underscoring the contribution of molecular defects to the insulin resistant phenotype. This...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Karlsson HK,Zierath JR

    更新日期:2007-01-01 00:00:00

  • Effect of sulforaphane on growth inhibition in human brain malignant glioma GBM 8401 cells by means of mitochondrial- and MEK/ERK-mediated apoptosis pathway.

    abstract::In recent studies, sulforaphane (SFN) has been seen to demonstrate antioxidant and anti-tumor activities as well as potent chemopreventive action against cancer. The present study investigates the anti-proliferation (using MTT assay, SFN demonstrated cytotoxic activity against GBM 8401 cell with IC(50) values at 35.52...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Huang TY,Chang WC,Wang MY,Yang YR,Hsu YC

    更新日期:2012-07-01 00:00:00

  • Influence of Regional Difference in Bone Mineral Density on Hip Fracture Site in Elderly Females by Finite Element Analysis.

    abstract::Hip fracture is a kind of osteoporotic fractures in elderly patients. Its important monitoring indicator is to measure bone mineral density (BMD) using DXA. The stress characteristics and material distribution in different parts of the bones can be well simulated by three-dimensional finite element analysis. Our previ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Lin ZL,Li PF,Pang ZH,Zheng XH,Huang F,Xu HH,Li QL

    更新日期:2015-11-01 00:00:00

  • Modulation of cell signaling pathways by Kaposi's sarcoma-associated herpesvirus (KSHVHHV-8).

    abstract::Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, has been associated with the development of Kaposi's sarcoma, pleural effusion lymphoma, and multicentric Castleman's disease. KSHV is a double-stranded DNA virus that has been classified as a gammaherpesvirus. The viral genome is appro...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Damania B

    更新日期:2004-01-01 00:00:00

  • Slow inactivation in voltage-gated sodium channels: molecular substrates and contributions to channelopathies.

    abstract::Slow inactivation in voltage-gated sodium channels is a biophysical process that governs the availability of sodium channels over extended periods of time. Slow inactivation, therefore, plays an important role in controlling membrane excitability, firing properties, and spike frequency adaptation. Defective slow inact...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Vilin YY,Ruben PC

    更新日期:2001-01-01 00:00:00

  • Effects of tumor necrosis factor inhibitor on serum level of HLA-B27 and PDCD-1 in patients with ankylosing spondylitis.

    abstract::The aim of this study was to evaluate the effect of tumor necrosis factor-alpha (TNF-α) inhibitor-infliximab on ankylosing spondylitis (AS) patients and detect the serum level of HLA-B27 and PDCD-1 before and after TNF inhibitor treatment. 138 patients at active stage of AS were treated with infliximab; serum was coll...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Chen X,Zhou X,Li X,Tang J,Hu X,Wang J,Xu C

    更新日期:2014-11-01 00:00:00

  • Inhibition of hepatitis B virus cccDNA by siRNA in transgenic mice.

    abstract::The elimination of viral covalently closed circular DNA (cccDNA) from the nucleus of infected hepatocytes is an obstacle to achieving sustained viral clearance during antiviral therapy of chronic hepatitis B virus (HBV) infection. The aim of our study was to determine whether treatment with siRNA is able to suppress v...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Li G,Jiang G,Lu J,Chen S,Cui L,Jiao J,Wang Y

    更新日期:2014-07-01 00:00:00

  • Redox buffer capacity of the cell: theoretical and experimental approach.

    abstract::Reactive oxygen species (ROS) are involved in a variety of biological phenomena, such as mutation, carcinogenesis, inflammation, aging, development, and signal transduction. Intracellular generation of ROS might lead to the activation of redox signaling or oxidative stress. Nonetheless, it is difficult to estimate whe...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Martinovich GG,Martinovich IV,Cherenkevich SN,Sauer H

    更新日期:2010-11-01 00:00:00

  • Multicenter study on adult growth hormone level in postoperative pituitary tumor patients.

    abstract::The objective of this study is to observe the adult growth hormone level in postoperative pituitary tumor patients of multi-centers, and explore the change of hypophyseal hormones in postoperative pituitary tumor patients. Sixty patients with pituitary tumor admitted during March, 2011-March, 2012 were selected. Posto...

    journal_title:Cell biochemistry and biophysics

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Cheng JM,Gu JW,Kuang YQ,Ma Y,Xia X,Yang T,Lu M,He WQ,Sun ZY,Zhang YC

    更新日期:2015-03-01 00:00:00

  • Acute adaptations of the coronary circulation to exercise.

    abstract::Coronary blood flow is tightly coupled to myocardial oxygen consumption to maintain a consistently high level of myocardial oxygen extraction. This tight coupling has been proposed to depend on periarteriolar oxygen tension, signals released from cardiomyocytes (adenosine acting on K+(ATP) channels), and/or the endoth...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Duncker DJ,Merkus D

    更新日期:2005-01-01 00:00:00

  • The protective effect of mitochondrial ATP-sensitive K+ channel opener, nicorandil, combined with Na+/Ca2+ exchange blocker KB-R7943 on myocardial ischemia-reperfusion injury in rat.

    abstract::To study the protective effect of mitochondrial ATP-sensitive K(+) channel (mitoK(ATP) channel) opener, nicorandil, combined with Na(+)/Ca(2+) exchange blocker KB-R7943 on myocardial ischemia-reperfusion injury in isolated rat hearts; the isolated rat heart was perfused by modified Langendorff device, after 15-min bal...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Jia D

    更新日期:2011-07-01 00:00:00

  • Regulation of tetrahydrobiopterin synthesis and bioavailability in endothelial cells.

    abstract::Tetrahydrobiopterin (BH4) is a member of the pterin family that has a core structure of pyrazino-2,3-d-pyrimidine rings. Because BH4 is an essential cofactor for the biosynthesis of nitric oxide (a major vasodilator), there is growing interest in BH4 biochemistry in endothelial cells (the cells that line blood vessels...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Shi W,Meininger CJ,Haynes TE,Hatakeyama K,Wu G

    更新日期:2004-01-01 00:00:00

  • Chromosome analysis using spectral karyotyping (SKY).

    abstract::Spectral karyotyping is a novel technique for chromosome analysis that has been developed based on the approach of the fluorescence in situ hybridization technique. Spectral karyotyping makes it feasible to diagnose a variety of diseases, because of its technology in painting each of the 24 human chromosomes with diff...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Imataka G,Arisaka O

    更新日期:2012-01-01 00:00:00

  • Association with leptin gene C.-2548 G>A polymorphism, serum leptin levels, and body mass index in Turkish obese patients.

    abstract::Leptin is a protein hormone which plays a critical role in the regulation of both body-weight through reducing food intake and stimulating energy expenditure. Several polymorphisms in leptin gene (LEP), which encodes for leptin, have been described. However, its association with obesity is still controversial. Therefo...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Sahin DS,Tumer C,Demir C,Celik MM,Celik M,Ucar E,Gunesacar R

    更新日期:2013-03-01 00:00:00

  • Deciphering Biophysical Modulation in Ovarian Cancer Cells.

    abstract::It has been long known that the oncogenic extracellular environment plays an indispensable role in developing and nurturing cancer cell progression and in resistance to standard treatments. However, by how much the biophysical components of tumour extracellular environment contribute to these processes is uncertain. I...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Sarwar M,Sykes PH,Chitcholtan K,Evans JJ

    更新日期:2021-01-12 00:00:00

  • Photoreactivity of Bis-retinoid A2E Complexed with a Model Protein in Selected Model Systems.

    abstract::The bis-retinoid N-retinyl-N-retinylidene ethanolamine (A2E) is formed as a byproduct of visual cycle in retinal pigment epithelium (RPE). It contributes to golden-yellow fluorescence of the age pigment lipofuscin, which accumulates in RPE. Lipofuscin can generate a variety of reactive oxygen species (ROS) upon blue-l...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Furso J,Zadlo A,Szewczyk G,Sarna TJ

    更新日期:2020-12-01 00:00:00

  • Non-steroidal anti-inflammatory drugs and hypertension.

    abstract::Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used to alleviate pain of the patients who suffer from inflammatory conditions like rheumatoid arthritis, osteoarthritis, and other painful conditions like gout. This class of drugs works by blocking cyclooxgenases which in turn block the prostaglandin prod...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Zheng L,Du X

    更新日期:2014-06-01 00:00:00

  • Combined hepatocellular-cholangiocarcinoma with fever of unknown origin: a case report and review of literature.

    abstract::Combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) is a rare form of primary liver cancer (PLC). It is difficult to make a correct preoperative diagnosis of cHCC-CC because of the lack of special features of the disease. We here present a case of a 68-year-old man who presented with fluctuant fever, ch...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: E C,Xie Y,Yang Y,Ji D,Li W,Zhang X

    更新日期:2014-05-01 00:00:00

  • Anticancer effects of chemokine receptor 4(CXCR4) gene silenced by CXCR4-siRNA in nude mice model of ovarian cancer.

    abstract::The aim is to study the anticancer effect of CXCR4 gene knockdown by CXCR4-siRNA in nude mice model of ovarian cancer. Injecti the SW626 tumor cells which had been transfected by vectors to make nude mouse model of ovarian cancer. The model mice were divided into interference group, negative control group, and blank c...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Liu W,Wang Y,Wang H,Wang A

    更新日期:2014-12-01 00:00:00

  • Ecto-mesenchymal stem cells from facial process: potential for muscle regeneration.

    abstract::Ecto-mesenchymal stem cells (EMSCs) originate from the cranial neural crest and participate in the formation of tooth, salivary, and muscle in early development stage. The transplantation of EMSCs, a potential source of myoblast stem cell, might improve muscle regeneration. The purpose of this study was to explore whe...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Nie X,Xing Y,Deng M,Gang L,Liu R,Zhang Y,Wen X

    更新日期:2014-09-01 00:00:00

  • Translating biomaterial properties to intracellular signaling.

    abstract::Bioactive materials present important micro-environmental cues that induce specific intracellular signaling responses which ultimately determine cell behavior. For example, vascular endothelial cells on a normal vessel wall resist inflammation and thrombosis, but the same cells seeded on an artificial vascular graft o...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审


    authors: Caplan MR,Shah MM

    更新日期:2009-01-01 00:00:00

  • Anti-proliferative Effect of Physcion on Human Gastric Cell Line via Inducing ROS-Dependent Apoptosis.

    abstract::In this study, the anti-proliferative effect of physcion, an anthraquinone derivative isolated and characterized from both terrestrial and marine sources, against human gastric cancer SGC-7901 cells was investigated and the underlying mechanisms were explored. Physcion reduced SGC-7901 cell viability in a dose- and ti...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章


    authors: Xiong Y,Ren L,Wang Z,Hu Z,Zhou Y

    更新日期:2015-11-01 00:00:00