The Role of Arachidonic Acid Metabolism in Myocardial Ischemia-Reperfusion Injury.

Abstract:

:Patients with myocardial ischemic diseases or who are undergoing one of various heart treatments, such as open heart surgery, coronary artery bypass grafting, percutaneous coronary artery intervention or drug thrombolysis, face myocardial ischemia-reperfusion injury (MIRI). However, no effective treatment is currently available for MIRI. To improve the prognosis of people with cardiovascular disease, it is important to research the mechanism of MIRI. Arachidonic acid (AA) is one of the focuses of current research. The various metabolic pathways of AA are closely related to the development of cardiovascular disease, and the roles of various metabolites in ischemia-reperfusion injury have gradually been confirmed. AA is mainly metabolized in the cyclooxygenase (COX) pathway, lipoxygenase (LOX) pathway, and cytochrome P450 monooxygenase (CYP) pathway. This paper summarizes the progress of research on these three major AA metabolic pathways with respect to MIRI.

journal_name

Cell Biochem Biophys

authors

Zhang C,He M,Ni L,He K,Su K,Deng Y,Li Y,Xia H

doi

10.1007/s12013-020-00928-z

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

255-265

issue

3

eissn

1085-9195

issn

1559-0283

pii

10.1007/s12013-020-00928-z

journal_volume

78

pub_type

杂志文章,评审
  • The Inhibiting Effect of Dinitrosyl Iron Complexes with Thiol-containing Ligands on the Growth of Endometrioid Tumours in Rats with Experimental Endometriosis.

    abstract::The possibility that binuclear dinitrosyl iron complexes with glutathione and cysteine (DNIC-GSН and B-DNIC-Cys) have a strong cytotoxic effect on the growth of endometrioid tumours (EMT) in rats with surgically induced experimental endometriosis established in our previous studies has been supported with experimental...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-019-00865-6

    authors: Burgovа EN,Khristidis YI,Kurkov AV,Mikoyan VD,Shekhter AB,Adamyan LV,Timashev PS,Vanin AF

    更新日期:2019-03-01 00:00:00

  • Activation of p38 MAPK pathway by hepatitis C virus E2 in cells transiently expressing DC-SIGN.

    abstract::Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) is a cellular receptor for hepatitis C virus for the binding of viral envelope glycoprotein E2. Interaction of DC-SIGN with the E2 may evoke cellular signal transduction implicated in viral pathogenesis. We developed a cell model ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-009-9069-0

    authors: Chen QL,Zhu SY,Bian ZQ,Zhao LJ,Cao J,Pan W,Qi ZT

    更新日期:2010-01-01 00:00:00

  • Spectral CT imaging in patients with Budd-Chiari syndrome: investigation of image quality.

    abstract::To assess the image quality of monochromatic imaging from spectral CT in patients with Budd-Chiari syndrome (BCS), fifty patients with BCS underwent spectral CT to generate conventional 140 kVp polychromatic images (group A) and monochromatic images, with energy levels from 40 to 80, 40 + 70, and 50 + 70 keV fusion im...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0021-6

    authors: Su L,Dong J,Sun Q,Liu J,Lv P,Hu L,Yan L,Gao J

    更新日期:2014-11-01 00:00:00

  • Modulation of ion channel function by P2Y receptors.

    abstract::P2Y receptors are classified as P2 purinergic receptors that belong to the superfamily of G-protein coupled receptors. They are distinguishable from P1 (adenosine) receptors in that they bind adenine and/or uracil nucleotide triphosphates or diphosphates depending on the subtype. Over the past decade, P2Y receptors ha...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1385/CBB:39:1:75

    authors: Lee SY,O'Grady SM

    更新日期:2003-01-01 00:00:00

  • Lipids Composition in Plant Membranes.

    abstract::The paper focuses on the selected plant lipid issues. Classification, nomenclature, and abundance of fatty acids was discussed. Then, classification, composition, role, and organization of lipids were displayed. The involvement of lipids in xantophyll cycle and glycerolipids synthesis (as the most abundant of all lipi...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s12013-020-00947-w

    authors: Reszczyńska E,Hanaka A

    更新日期:2020-12-01 00:00:00

  • CT diagnosis in the thecoma-fibroma group of the ovarian stromal tumors.

    abstract::The aim of this study was to investigate characteristic CT manifestations of the group of ovarian thecoma-fibroma. 24 patients (26 lesions) presenting with the ovarian thecoma-fibroma were analyzed retrospectively, and the diagnosis were confirmed by pathology after surgery. Our findings included: 22 patients were uni...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0288-7

    authors: Zhang Z,Wu Y,Gao J

    更新日期:2015-03-01 00:00:00

  • Clinical application of a dendritic cell vaccine raised against heat-shocked glioblastoma.

    abstract::Establishment of a detection platform for glioblastoma-dendritic cell (DC) vaccine preparation and to determine the efficacy of the vaccine in a clinical trial. Autologous glioblastoma-DC vaccine was prepared from a glioblast specimen procured from surgical resection. The specimen was used to enrich the vaccine with p...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-011-9265-6

    authors: Jie X,Hua L,Jiang W,Feng F,Feng G,Hua Z

    更新日期:2012-01-01 00:00:00

  • Influence of topoisomerase II inhibitors and ionizing radiation on growth arrest and cell death pathways in the breast tumor cell.

    abstract::Promotion of apoptosis (which is frequently dependent on functional p53) is thought to be critical for the effectiveness of chemotherapy or radiotherapy. Studies in this as well as other laboratories have demonstrated that breast tumor cells are relatively refractory to apoptosis in response to modalities that induce ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1385/CBB:33:1:19

    authors: Gewirtz DA,Sundaram S,Magnet KJ

    更新日期:2000-01-01 00:00:00

  • Omega-3 Fatty Acids and Primary and Secondary Prevention of Cardiovascular Disease.

    abstract::The prevalence of cardiovascular disease (CVD) is increasing dramatically especially in developing countries like India. CVD is a leading cause of morbidity and mortality. There has been a growing awareness of the role of nutrients in the prevention of CVD. One specific recommendation in the battle against CVD is the ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s12013-014-0407-5

    authors: Cao Y,Lu L,Liang J,Liu M,Li X,Sun R,Zheng Y,Zhang P

    更新日期:2015-05-01 00:00:00

  • Toward mechanical manipulations of cell membranes and membrane proteins using an atomic force microscope: an invited review.

    abstract::Recent advances in the use of the atomic force microscope (AFM) for manipulating cell membranes and membrane proteins are reviewed. Early pioneering work on measurements of the magnitude of the force required to create indentations with defined depth on their surfaces and to separate interacting pairs of avidin-biotin...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1385/CBB:39:3:257

    authors: Ikai A,Afrin R

    更新日期:2003-01-01 00:00:00

  • Modulation of cell signaling pathways by Kaposi's sarcoma-associated herpesvirus (KSHVHHV-8).

    abstract::Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, has been associated with the development of Kaposi's sarcoma, pleural effusion lymphoma, and multicentric Castleman's disease. KSHV is a double-stranded DNA virus that has been classified as a gammaherpesvirus. The viral genome is appro...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1385/CBB:40:3:305

    authors: Damania B

    更新日期:2004-01-01 00:00:00

  • A causal analysis of intra-abdominal hemorrhage after reduced-size liver transplantation in rat.

    abstract::In this study, we analyzed causes of abdominal hemorrhage after reduced-size liver transplantation in rat. Healthy SD rats (weight range of 260-280 g) underwent liver transplantation, the donors were female and the recipients were male rats. The recipients were, on average, by <10 g heavier than the donors. All operat...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-011-9225-1

    authors: Jing L,Li L,Jiang-Hua R,Sheng-Ning Z,Zhu L,Lai-Bang L,Jiang L

    更新日期:2011-12-01 00:00:00

  • A proteomic analysis of placental trophoblastic cells in preeclampsia-eclampsia.

    abstract::To explore the proteomic changes of placental trophoblastic cells in preeclampsia-eclampsia (PE), placental trophoblastic cells from normally pregnant women and women with hypertension during gestational period were prepared by laser capture microdissection (LCM), and proteins isolated from these cells were subjected ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9792-4

    authors: Ma K,Jin H,Hu R,Xiong Y,Zhou S,Ting P,Cheng Y,Yang Y,Yang P,Li X

    更新日期:2014-06-01 00:00:00

  • Comparison of Gene Expression Profile Between Tumor Tissue and Adjacent Non-tumor Tissue in Patients with Gastric Gastrointestinal Stromal Tumor (GIST).

    abstract::Gastrointestinal stromal tumors (GISTs) are defined as spindle cell and/or epithelioid tumors originated from interstitial Cajal cells or precursors in the digestive tract. This study was conducted to identify genes differing in expression between the gastric tumors and the adjacent non-cancerous mucosas in patients w...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0504-5

    authors: Kou Y,Zhao Y,Bao C,Wang Q

    更新日期:2015-06-01 00:00:00

  • Molecular dynamics simulation of a high-affinity antibody-protein complex: the binding site is a mosaic of locally flexible and preorganized rigid regions.

    abstract::One nanosecond molecular dynamic (MD) simulation of anti-hen egg white lysozyme (HEL) antibody HyHEL63 (HH63) complexed with HEL reveals rigid and flexible regions of the HH63 binding site. Fifty conformations, extracted from the MD trajectory at regular time intervals were superimposed on HH63-HEL X-ray crystal struc...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/CBB:43:2:253

    authors: Sinha N,Smith-Gill SJ

    更新日期:2005-01-01 00:00:00

  • Preserved coupling of oxidative phosphorylation but decreased mitochondrial respiratory capacity in IL-1beta-treated human peritoneal mesothelial cells.

    abstract::The peritoneal mesothelium acts as a regulator of serosal responses to injury, infection, and neoplastic diseases. After inflammation of the serosal surfaces, proinflammatory cytokines induce an "activated" mesothelial cell phenotype, the mitochondrial aspect of which has not previously been studied. After incubation ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/CBB:44:2:179

    authors: Stadlmann S,Renner K,Pollheimer J,Moser PL,Zeimet AG,Offner FA,Gnaiger E

    更新日期:2006-01-01 00:00:00

  • Chromosome analysis using spectral karyotyping (SKY).

    abstract::Spectral karyotyping is a novel technique for chromosome analysis that has been developed based on the approach of the fluorescence in situ hybridization technique. Spectral karyotyping makes it feasible to diagnose a variety of diseases, because of its technology in painting each of the 24 human chromosomes with diff...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s12013-011-9285-2

    authors: Imataka G,Arisaka O

    更新日期:2012-01-01 00:00:00

  • Differential effects of G- and F-actin on the plasma membrane calcium pump activity.

    abstract::We have previously shown that plasma membrane calcium ATPase (PMCA) pump activity is affected by the membrane protein concentration (Vanagas et al., Biochim Biophys Acta 1768:1641-1644, 2007). The results of this study provided evidence for the involvement of the actin cytoskeleton. In this study, we explored the rela...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-012-9467-6

    authors: Vanagas L,de La Fuente MC,Dalghi M,Ferreira-Gomes M,Rossi RC,Strehler EE,Mangialavori IC,Rossi JP

    更新日期:2013-05-01 00:00:00

  • Transforming growth factor-beta1 and disorders of the lung.

    abstract::The transforming growth factor (TGF) superfamily encompasses about 30 members in mammals. The effect of TGF-beta subfamily members is exerted and regulated via selective pathways of synthesis and signaling that involve activation of latent TGF-beta, specific and high-affinity binding to cell membrane serine/threonine ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1385/CBB:43:1:131

    authors: Camoretti-Mercado B,Solway J

    更新日期:2005-01-01 00:00:00

  • Surfactin induces apoptosis and G(2)/M arrest in human breast cancer MCF-7 cells through cell cycle factor regulation.

    abstract::Surfactin, purified from Bacillus subtilis natto TK-1, inhibited proliferation of human breast cancer MCF-7 cells in a dose- and time-dependent manner, with IC(50) at 24, 48, and 72 h of 82.6, 27.3, and 14.8 microM, respectively. Surfactin-induced cell death was considered to be apoptotic by observing the typical apop...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-009-9065-4

    authors: Cao X,Wang AH,Jiao RZ,Wang CL,Mao DZ,Yan L,Zeng B

    更新日期:2009-01-01 00:00:00

  • MT2A Promotes Oxaliplatin Resistance in Colorectal Cancer Cells.

    abstract::We aimed to understand the molecular mechanism underlying the incidence of Oxaliplatin resistance in colorectal cancer. The Oxaliplatin-resistant (OR) HT29 colorectal cell line was established by long-term exposure to Oxaliplatin. Cell viability and proliferation were determined by the 3-(4,5-dimethyl thiazol-2-yl)-2,...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-020-00930-5

    authors: Zhao Z,Zhang G,Li W

    更新日期:2020-12-01 00:00:00

  • The significance and mechanism of propofol on treatment of ischemia reperfusion induced lung injury in rats.

    abstract::This study is aimed to investigate the efficacy and underlying the mechanism of propofol in treatment of ischemia reperfusion (IR)-induced lung injury in rats, providing a novel insight of therapeutic strategy for IR-induced lung injury. 120 healthy SD rats were selected and randomly divided into sham operation group,...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0088-0

    authors: Yang P,Yang N,Zhang X,Xu X

    更新日期:2014-12-01 00:00:00

  • Expression and purification of rotavirus proteins NSP5 and NSP6 in Escherichia coli.

    abstract::Rotaviruses are one of the worldwide leading causes of gastroenteritis in children under 5 yr old. The rotavirus nonstructural NSP5 is a phosphoprotein implicated in viroplasms formation, whereas NSP6 could have a possible regulatory role of NSP5. It has been reported that N- and C-termini of NSP5 are important for th...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/CBB:44:3:336

    authors: Samaniego-Hernández M,De León-Rodriguez A,Aparicio-Fabre R,Arias-Ortiz C,Barba de la Rosa AP

    更新日期:2006-01-01 00:00:00

  • Endocardial endothelial cells stimulate proliferation and collagen synthesis of cardiac fibroblasts.

    abstract::Given that vascular endothelial cells play an important role in the modulation of vascular structure and function, we hypothesized that endocardial endothelial cells (EECs) may have a modulator role in regulating the cardiac interstitial cells. Endocardial endothelial cells were isolated from freshly collected pig hea...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/cbb:47:1:65

    authors: Kuruvilla L,Nair RR,Umashankar PR,Lal AV,Kartha CC

    更新日期:2007-01-01 00:00:00

  • On the analysis of large-scale genomic structures.

    abstract::We apply methods from statistical physics (histograms, correlation functions, fractal dimensions, and singularity spectra) to characterize large-scale structure of the distribution of nucleotides along genomic sequences. We discuss the role of the extension of noncoding segments ("junk DNA") for the genomic organizati...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/CBB:42:2:145

    authors: Oiwa NN,Goldman C

    更新日期:2005-01-01 00:00:00

  • Insulin signaling and glucose transport in insulin resistant human skeletal muscle.

    abstract::Insulin increases glucose uptake and metabolism in skeletal muscle by signal transduction via protein phosphorylation cascades. Insulin action on signal transduction is impaired in skeletal muscle from Type 2 diabetic subjects, underscoring the contribution of molecular defects to the insulin resistant phenotype. This...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s12013-007-0030-9

    authors: Karlsson HK,Zierath JR

    更新日期:2007-01-01 00:00:00

  • Better prognosis in newborns with trisomy 13 who received intensive treatments: a retrospective study of 16 patients.

    abstract::Intensive treatment for newborns with trisomy 13 is controversial because of their lethal prognosis. We report the better life prognosis of patients with trisomy 13 who received intensive treatment. At our hospital, we provided an intensive management to such patients including resuscitation and surgical procedures as...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-012-9355-0

    authors: Tsukada K,Imataka G,Suzumura H,Arisaka O

    更新日期:2012-07-01 00:00:00

  • Extracting the stepping dynamics of molecular motors in living cells from trajectories of single particles.

    abstract::Molecular motors are responsible of transporting a wide variety of cargos in the cytoplasm. Current efforts are oriented to characterize the biophysical properties of motors in cells with the aim of elucidating the mechanisms of these nanomachines in the complex cellular environment. In this study, we present an algor...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-012-9397-3

    authors: Bruno A,Bruno L,Levi V

    更新日期:2013-01-01 00:00:00

  • Effect of miR-21 on renal fibrosis by regulating MMP-9 and TIMP1 in kk-ay diabetic nephropathy mice.

    abstract::MicroRNAs (miRs) play important roles in initiation and progression of many pathologic processes. However, the roles of miRs in diabetic nephropathy remain unclear. This study was to determine whether miR-21 was involved in diabetic nephropathy and to explore the relationship between miR-21 and MMP9/TIMP1 expression i...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9539-2

    authors: Wang J,Gao Y,Ma M,Li M,Zou D,Yang J,Zhu Z,Zhao X

    更新日期:2013-11-01 00:00:00

  • Vascularized composite islet-kidney transplantation in a miniature swine model.

    abstract::Previous work from this laboratory has demonstrated that transplantation of allogeneic thymic tissue as part of a composite vascularized graft is far more successful in terms of both engraftment and long-term survival than transplantation of thymic tissue or cells alone. We have subsequently extended this concept to t...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s12013-007-0027-4

    authors: Vallabhajosyula P,Griesemer A,Yamada K,Sachs DH

    更新日期:2007-01-01 00:00:00