Modulation of ion channel function by P2Y receptors.

abstract：:Cyclic ADP-ribose (cADPR) is a cyclic metabolite of NAD+ synthesised in cells and tissues expressing ADP-ribosyl cyclases. Although it was first discovered in sea-urchin egg extracts as a potent calcium mobilizing agent, subsequent studies have indicated that it may have a widespread action in the activation of calciu...

journal_title：Cell biochemistry and biophysics

authors： Galione A,Cui Y,Empson R,Iino S,Wilson H,Terrar D

更新日期：1998-01-01 00:00:00

abstract：:Promotion of apoptosis (which is frequently dependent on functional p53) is thought to be critical for the effectiveness of chemotherapy or radiotherapy. Studies in this as well as other laboratories have demonstrated that breast tumor cells are relatively refractory to apoptosis in response to modalities that induce ...

journal_title：Cell biochemistry and biophysics

authors： Gewirtz DA,Sundaram S,Magnet KJ

更新日期：2000-01-01 00:00:00

abstract：:The CEP genes play a pivotal role in the replication of the cell. CEP family proteins form the major constituents of the centrosome and play a prominent role in centriole biogenesis and in cell replication. Alteration in CEP genes will result in disruption of cell cycle that may in turn cause cancer. In our study, we ...

journal_title：Cell biochemistry and biophysics

authors： Gopalakrishnan C,Kamaraj B,Purohit R

更新日期：2014-12-01 00:00:00

abstract：:Human salivary aldehyde dehydrogenase (hsALDH) enzyme appears to be the first line of defense in the body against exogenous toxic aldehydes. However till date much work has not been done on this important member of the ALDH family. In this study, we have purified hsALDH to homogeneity by diethylaminoethyl-cellulose (D...

journal_title：Cell biochemistry and biophysics

authors： Alam MF,Laskar AA,Choudhary HH,Younus H

更新日期：2016-09-01 00:00:00

abstract：:Gastrointestinal stromal tumors (GISTs) are defined as spindle cell and/or epithelioid tumors originated from interstitial Cajal cells or precursors in the digestive tract. This study was conducted to identify genes differing in expression between the gastric tumors and the adjacent non-cancerous mucosas in patients w...

journal_title：Cell biochemistry and biophysics

authors： Kou Y,Zhao Y,Bao C,Wang Q

更新日期：2015-06-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of tumor necrosis factor-alpha (TNF-α) inhibitor-infliximab on ankylosing spondylitis (AS) patients and detect the serum level of HLA-B27 and PDCD-1 before and after TNF inhibitor treatment. 138 patients at active stage of AS were treated with infliximab; serum was coll...

journal_title：Cell biochemistry and biophysics

authors： Chen X,Zhou X,Li X,Tang J,Hu X,Wang J,Xu C

更新日期：2014-11-01 00:00:00

abstract：:There are over 10,000 C2H2-type zinc finger (ZF) domains distributed among more than 1,000 ZF proteins in the human genome. These domains are frequently observed to be involved in sequence-specific DNA binding, and uncharacterized domains are typically assumed to facilitate DNA interactions. However, some ZFs also fac...

journal_title：Cell biochemistry and biophysics

authors： Brayer KJ,Kulshreshtha S,Segal DJ

更新日期：2008-01-01 00:00:00

abstract：:The study analyzed how enteral ecoimmunonutrition, which comprises probiotics, glutamine, fish oil, and Enteral Nutritional Suspension (TPF), can impact on the enteral permeability and serum Ghrelin activity in severe cerebral stroke patients with lung infection. Among 190 severe cerebral stroke patients with toleranc...

journal_title：Cell biochemistry and biophysics

authors： Xu XD,Shao F

更新日期：2015-01-01 00:00:00

abstract：:The study's objective was to evaluate the applicability of different endovascular methods for treatment of refractory type of Budd-Chiari syndrome (BCS) under specific scenarios frequently encountered in patients. The treatment methods were evaluated in 197 patients with the following four types of refractory BCS: les...

journal_title：Cell biochemistry and biophysics

authors： Gao Y,Chen S,Yu C

更新日期：2011-11-01 00:00:00

abstract：:Structural organization of the cytoplasm by compartmentation is a well established fact for the eukaryotic cell. In prokaryotes, compartmentation is less obvious. Most prokaryotes do not need intracytoplasmic membranes to maintain their vital functions. This review, especially dealing with prokaryotes, will point out ...

journal_title：Cell biochemistry and biophysics

authors： Hoppert M,Mayer F

更新日期：1999-01-01 00:00:00

abstract：:Nano-drug delivery systems have proven to be an efficient formulation tool to overcome the challenges with current antibiotics therapy and resistance. A series of pH-responsive lipid molecules were designed and synthesized for future liposomal formulation as a nano-drug delivery system for vancomycin at the infection ...

journal_title：Cell biochemistry and biophysics

authors： Ahmed S,Vepuri SB,Jadhav M,Kalhapure RS,Govender T

更新日期：2018-06-01 00:00:00

abstract：:The overview demonstrates how the use of only one physico-chemical approach, viz., the electron paramagnetic resonance method, allowed detection and identification of dinitrosyl iron complexes with thiol-containing ligands in various animal and bacterial cells. These complexes are formed in biological objects in the p...

journal_title：Cell biochemistry and biophysics

authors： Vanin AF

更新日期：2018-06-01 00:00:00

abstract：:Characterization of the electroclinical features and evolution of childhood occipital epilepsy of Gastaut (COE-G). Seven children were retrospectively identified as having COE-G and were followed-up clinically using EEGs. Visual manifestations were the most common ictal event. Eye-associated ictal deviation was associ...

journal_title：Cell biochemistry and biophysics

authors： Shu XM,Zhang GP,Yang BZ,Li J

更新日期：2013-01-01 00:00:00

abstract：:Slow inactivation in voltage-gated sodium channels is a biophysical process that governs the availability of sodium channels over extended periods of time. Slow inactivation, therefore, plays an important role in controlling membrane excitability, firing properties, and spike frequency adaptation. Defective slow inact...

journal_title：Cell biochemistry and biophysics

authors： Vilin YY,Ruben PC

更新日期：2001-01-01 00:00:00

abstract：:The objective of this study is to explore the incidence of inherited metabolic disorders (IMD) in infants with infantile spasms (IS), with an attempt to improve the early diagnosis and etiological and symptomatic treatment. Urine and blood samples were collected from 60 IS patients and analyzed for the quantification ...

journal_title：Cell biochemistry and biophysics

authors： Liu XM,Li R,Chen SZ,Sang Y,Chen J,Fan CH

更新日期：2015-05-01 00:00:00

abstract：:This study is aimed to investigate the efficacy and underlying the mechanism of propofol in treatment of ischemia reperfusion (IR)-induced lung injury in rats, providing a novel insight of therapeutic strategy for IR-induced lung injury. 120 healthy SD rats were selected and randomly divided into sham operation group,...

journal_title：Cell biochemistry and biophysics

authors： Yang P,Yang N,Zhang X,Xu X

更新日期：2014-12-01 00:00:00

abstract：:Excessive proliferation of vascular smooth muscle cells is one of the main pathological processes leading to atherosclerosis and intimal hyperplasia after vascular interventional therapy. Our previous study has shown that interferon-γ inducible protein-10 contributes to the proliferation of vascular smooth muscle cell...

journal_title：Cell biochemistry and biophysics

authors： Wang HJ,Zhou Y,Liu RM,Qin YS,Cen YH,Hu LY,Wang SM,Hu ZJ

更新日期：2017-03-01 00:00:00

abstract：:Myocardium viability in ischemic heart failure (HF) may affect the effect of cardiac resynchronization therapy (CRT). We hypothesized that longitudinal strain of 2D-STE, which reflects myocardium viability, can predict the response to CRT in patients with ischemic HF. 2D-STE was performed in 42 patients with HF, 1 wee...

journal_title：Cell biochemistry and biophysics

authors： Ma CY,Liu S,Yang J,Tang L,Zhang LM,Li N,Yu B

更新日期：2014-09-01 00:00:00

abstract：:The objective of this study is to investigate the roles of acteoside (ACT) in cells with oxygen-glucose deprivation and reoxygenation (OGD/R)-induced injury and the underlying mechanisms. The differentially expressed genes (DEGs) in rats with middle cerebral artery occlusion were identified using GSE61616 data set. Ky...

journal_title：Cell biochemistry and biophysics

authors： Wu W,Wu G,Cao D

更新日期：2021-01-13 00:00:00

abstract：:To evaluate the correlation between CT perfusion parameters and tumor angiogenesis, expression of VEGF is implanted in VX2 lung tumor. VX2 tumor cells were injected in 15 healthy New Zealand rabbits. After 20 days, tumors with diameter over 7 mm were scanned with 16 row spiral CT. Using Software Perfusion 3, blood flo...

journal_title：Cell biochemistry and biophysics

authors： Ling S,Deng D,Mo Y,Zhang X,Guan X,Wei Q

更新日期：2014-09-01 00:00:00

abstract：:Far from now are the days when investigators raced to identify the proteolytic system responsible for the degradation of their favorite protein. Nowadays, it is well accepted that a given protein can be degraded by different systems depending on factors such as cell type, cellular conditions, or functionality of each ...

journal_title：Cell biochemistry and biophysics

authors： Park C,Cuervo AM

更新日期：2013-09-01 00:00:00

abstract：:Acid-base equilibria and interfacial electrostatic properties of hydrated mesoporous and nanostructured alumina powders are determining factors for the use of these materials in heterogeneous catalysis and as a sorption media for filtration and chromatographic applications including life sciences. Here spin probe elec...

journal_title：Cell biochemistry and biophysics

authors： Kovaleva EG,Molochnikov LS,Stepanova DP,Pestov AV,Trofimov DG,Kirilyuk IA,Smirnov AI

更新日期：2017-06-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, has been associated with the development of Kaposi's sarcoma, pleural effusion lymphoma, and multicentric Castleman's disease. KSHV is a double-stranded DNA virus that has been classified as a gammaherpesvirus. The viral genome is appro...

journal_title：Cell biochemistry and biophysics

authors： Damania B

更新日期：2004-01-01 00:00:00

abstract：:A sensitive and reliable ultra-pressure liquid chromatography with tandem mass spectrometry (UPLC-MS) was developed and validated for simultaneous quantification of six main bioactive components, i.e., calycosin-7-O-β-D-glucoside, ononin, calycosin, formononetin, astragaloside IV, and astragaloside II in rat plasma af...

journal_title：Cell biochemistry and biophysics

authors： Liu XH,Zhao JB,Guo L,Yang YL,Hu F,Zhu RJ,Feng SL

更新日期：2014-09-01 00:00:00

abstract：:Azurin, a small blue copper protein from the bacterial species Pseudomonas aeruginosa, is mostly a beta-sheet protein arranged into a single domain. Previous folding studies have shown that the equilibrium denaturation of the holoprotein follows a two-state process; however, upon removal of the copper, the denaturatio...

journal_title：Cell biochemistry and biophysics

authors： Hansen JE,McBrayer MK,Robbins M,Suh Y

更新日期：2002-01-01 00:00:00

abstract：:Danggui Sini decoction (DSD), a famous Chinese medicine, has been used therapeutically in various diseases. In this study, we tried to investigate whether and how DSD could ameliorate myelosuppression in an animal model, in which myelosuppression is induced by cyclophosphamide treatment. The myelosuppression model was...

journal_title：Cell biochemistry and biophysics

authors： Chen QQ,Han X,Wang WM,Zhao L,Chen A

更新日期：2015-03-01 00:00:00

abstract：:To investigate if the 12-lead resting electrocardiogram (ECG) is a predictor of left ventricular (LV) functional recovery after revascularization of chronic total coronary artery occlusions (CTO). Revascularization was performed in 58 CTO patients who had impaired regional wall motion. The 12-lead resting ECG was used...

journal_title：Cell biochemistry and biophysics

authors： Yue W,Wang G,Zhang X,Chen B,Wang X,Huangfu F,Jia R

更新日期：2014-09-01 00:00:00

abstract：:Pro-domain of a cysteine cathepsin contains a highly conserved Ex2Rx2Fx2Nx3Ix3N (ERFNIN) motif. The zymogen structure of cathepsins revealed that the Arg(R) residue of the motif is a central residue of a salt-bridge/H-bond network, stabilizing the scaffold of the pro-domain. Importance of the arginine is also demonstr...

journal_title：Cell biochemistry and biophysics

authors： Aich P,Biswas S

更新日期：2018-06-01 00:00:00

abstract：:Molecular motors are responsible of transporting a wide variety of cargos in the cytoplasm. Current efforts are oriented to characterize the biophysical properties of motors in cells with the aim of elucidating the mechanisms of these nanomachines in the complex cellular environment. In this study, we present an algor...

journal_title：Cell biochemistry and biophysics

authors： Bruno A,Bruno L,Levi V

更新日期：2013-01-01 00:00:00

abstract：:Our objective is to investigate the promoting effect of hypoxic preconditioning combined with microbubble (MB)-mediated ultrasound (US) on the SDF-1/CXCR4 expression and the migration ability of mesenchymal stem cells (MSCs). Based on the uniform design, the parameters of MB-mediated US, such as the total treatment ti...

journal_title：Cell biochemistry and biophysics

authors： Li L,Wu S,Li P,Zhuo L,Gao Y,Xu Y

更新日期：2015-12-01 00:00:00