Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells.

abstract：UNLABELLED:Epstein-Barr virus (EBV) is a well-established B-cell-tropic virus associated with various lymphoproliferative diseases of both B-cell and non-B-cell origin. EBV is associated with a number of T-cell lymphomas; however, in vitro studies utilizing prototypical EBV type 1 (EBV-1) laboratory strains have genera...

journal_title：Journal of virology

authors： Coleman CB,Wohlford EM,Smith NA,King CA,Ritchie JA,Baresel PC,Kimura H,Rochford R

更新日期：2015-02-01 00:00:00

abstract：:A region of the herpesvirus saimiri genome encoding an mRNA with two open reading frames (ORFs) has been identified to be essential for transformation of T cells. Deletion of either ORF resulted in the loss of transforming ability. ORF-1 has been shown to code for a collagen-like oncoprotein. This study shows for the ...

journal_title：Journal of virology

authors： Lund T,Medveczky MM,Geck P,Medveczky PG

更新日期：1995-07-01 00:00:00

abstract：:Viral recombination has been postulated to play two roles in the development of human immunodeficiency virus (HIV) resistance to antiretroviral drugs. First, recombination has the capacity to associate resistance mutations expressed by distinct viruses, thereby contributing to the development of viruses with improved ...

journal_title：Journal of virology

authors： Nora T,Charpentier C,Tenaillon O,Hoede C,Clavel F,Hance AJ

更新日期：2007-07-01 00:00:00

abstract：:Bacteriophage T4 gene 32 encodes a DNA unwinding protein required for DNA replication, repair, and recombination. Gene 32 temperature-sensitive mutations enhance virtually all base pair substitution mutation rates. ...

journal_title：Journal of virology

authors： Koch RE,McGaw MK,Drake JW

更新日期：1976-08-01 00:00:00

abstract：:The G glycoprotein of human respiratory syncytial virus (RSV) was identified previously as the viral attachment protein. Although we and others recently showed that G is not essential for replication in vitro, it does affect the efficiency of replication in a cell type-dependent fashion and is required for efficient r...

journal_title：Journal of virology

authors： Teng MN,Collins PL

更新日期：2002-06-01 00:00:00

abstract：:The simian picornaviruses were isolated from various primate tissues during the development of general tissue culture methods in the 1950s to 1970s or from specimens derived from primates used in biomedical research. Twenty simian picornavirus serotypes are recognized, and all are presently classified within the Enter...

journal_title：Journal of virology

authors： Oberste MS,Maher K,Pallansch MA

更新日期：2002-02-01 00:00:00

abstract：UNLABELLED:The discovery that measles virus (MV) uses the adherens junction protein nectin-4 as its epithelial receptor provides a new vantage point from which to characterize its rapid spread in the airway epithelium. We show here that in well-differentiated primary cultures of airway epithelial cells from human donor...

journal_title：Journal of virology

authors： Singh BK,Hornick AL,Krishnamurthy S,Locke AC,Mendoza CA,Mateo M,Miller-Hunt CL,Cattaneo R,Sinn PL

更新日期：2015-07-01 00:00:00

abstract：:The humoral immune response of cats that were naturally infected with the feline leukemia virus (FeLV) was examined after antigenic stimulation with the synthetic antigen poly(L-Tyr, L-Glu)-poly(DL-Ala)-poly(L-Lys). The primary humoral antibody response in FeLV-infected cats was both delayed and greatly reduced, compa...

journal_title：Journal of virology

authors： Wernicke D,Trainin Z,Ungar-Waron H,Essex M

更新日期：1986-11-01 00:00:00

abstract：:We used deep sequencing of poly(A) RNA to characterize the transcriptome of an economically important eel virus, anguillid herpesvirus 1 (AngHV1), at a stage during the lytic life cycle when infectious virus was being produced. In contrast to the transcription of mammalian herpesviruses, the overall level of antisense...

journal_title：Journal of virology

authors： van Beurden SJ,Gatherer D,Kerr K,Galbraith J,Herzyk P,Peeters BP,Rottier PJ,Engelsma MY,Davison AJ

更新日期：2012-09-01 00:00:00

abstract：:Marek's disease herpesvirus A antigen (MDHV-A) was identified as a 61,000- to 65,000-dalton glycoprotein by sodium dodecyl sulfate-polyacrylamide gel electrophoresis after immunoprecipitation from the culture medium of both [35S]methionine- and [14C]glucosamine-labeled infected cells by specific rabbit serum directed ...

journal_title：Journal of virology

authors： Glaubiger C,Nazerian K,Velicer LF

更新日期：1983-03-01 00:00:00

abstract：:Although the envelope gene of human immunodeficiency virus type 1 shows considerable strain variability, cysteine residues of the envelope protein are strongly conserved, suggesting that they are important to the envelope structure. We constructed and analyzed mutants of a biologically active molecular clone of human ...

journal_title：Journal of virology

authors： Tschachler E,Buchow H,Gallo RC,Reitz MS Jr

更新日期：1990-05-01 00:00:00

abstract：:During ϕX174 morphogenesis, 240 copies of the external scaffolding protein D organize 12 pentameric assembly intermediates into procapsids, a reaction reconstituted in vitro In previous studies, ϕX174 strains resistant to exogenously expressed dominant lethal D genes were experimentally evolved. Resistance was achieve...

journal_title：Journal of virology

authors： Cherwa JE Jr.,,Tyson J,Bedwell GJ,Brooke D,Edwards AG,Dokland T,Prevelige PE,Fane BA

更新日期：2016-12-16 00:00:00

abstract：:The emergence in 1997 and continuance today of a highly lethal H5N1 avian influenza virus (AIV) causing human disease has raised concern about an impending pandemic and the need for a vaccine to prepare for such an occurrence. We previously generated an efficacious vesicular stomatitis virus (VSV)-based AIV vaccine ex...

journal_title：Journal of virology

authors： Schwartz JA,Buonocore L,Suguitan AL Jr,Silaghi A,Kobasa D,Kobinger G,Feldmann H,Subbarao K,Rose JK

更新日期：2010-05-01 00:00:00

abstract：:Strains of Theiler's murine encephalomyelitis virus (TMEV) are divided into two subgroups, TO and GDVII. TMEV strains show subgroup-specific virus growth and cell tropism and induce subgroup-specific diseases. Using site-directed mutagenesis, we demonstrated that the amino acid at position 57 of the leader protein (L(...

journal_title：Journal of virology

authors： Takano-Maruyama M,Ohara Y,Asakura K,Okuwa T

更新日期：2006-12-01 00:00:00

abstract：:Although parvoviruses are found throughout the animal kingdom, only the human pathogenic B19 virus has so far been shown to possess a limited host range, with erythroid progenitor cells as the main target cells supporting B19 propagation. The underlying mechanism of such erythroid tropism is still unexplained. Synthes...

journal_title：Journal of virology

authors： Pallier C,Greco A,Le Junter J,Saib A,Vassias I,Morinet F

更新日期：1997-12-01 00:00:00

abstract：:The highly syncytium-inducing M strain and the weakly syncytium-inducing SC strain of bovine parainfluenza 3 virus differ by a single amino acid substitution in each of the hemagglutinin-neuraminidase (HN) and membrane (M) proteins, while their fusion (F) proteins are identical (T. Shioda, S. Wakao, S. Suzu, and H. Sh...

journal_title：Journal of virology

authors： Sakai Y,Shibuta H

更新日期：1989-09-01 00:00:00

abstract：:Large numbers of polymorphonuclear leukocytes (PMNs) infiltrated the murine vaginal mucosa within 24 h after intravaginal inoculation with an attenuated strain of herpes simplex virus type 2 (HSV-2). The role of these cells in resolution of a primary genital infection and in protection of HSV-immune animals against ch...

journal_title：Journal of virology

authors： Milligan GN

更新日期：1999-08-01 00:00:00

abstract：:Activation of host innate immune responses was studied in severe acute respiratory syndrome coronavirus (SCV)-infected human A549 lung epithelial cells, macrophages, and dendritic cells (DCs). In all cell types, SCV-specific subgenomic mRNAs were seen, whereas no expression of SCV proteins was found. No induction of c...

journal_title：Journal of virology

authors： Ziegler T,Matikainen S,Rönkkö E,Osterlund P,Sillanpää M,Sirén J,Fagerlund R,Immonen M,Melén K,Julkunen I

更新日期：2005-11-01 00:00:00

abstract：:The Epstein-Barr virus (EBV) major envelope glycoprotein gp340 is the subject of current efforts to develop an EBV subunit vaccine. The importance of gp340-specific humoral immunity has been highlighted by studies of natural infection in humans and gp340 immunization of experimental animals. The former studies have de...

journal_title：Journal of virology

authors： Pither RJ,Zhang CX,Shiels C,Tarlton J,Finerty S,Morgan AJ

更新日期：1992-02-01 00:00:00

abstract：:Polyclonal and monoclonal antibodies to individual herpes simplex virus (HSV) glycoproteins were tested for ability to inhibit adsorption of radiolabeled HSV type 1 (HSV-1) strain HFEMsyn [HSV-1(HFEM)syn] to HEp-2 cell monolayers. Polyclonal rabbit antibodies specific for glycoprotein D (gD) or gC and three monoclonal...

journal_title：Journal of virology

authors： Fuller AO,Spear PG

更新日期：1985-08-01 00:00:00

abstract：:Sindbis virus (SINV) is an alphavirus that causes infection of neurons and encephalomyelitis in adult immunocompetent mice. Recovery can occur without apparent neurological damage. To better define the factors facilitating noncytolytic clearance of SINV in different regions of the central nervous system (CNS) and the ...

journal_title：Journal of virology

authors： Burdeinick-Kerr R,Wind J,Griffin DE

更新日期：2007-06-01 00:00:00

abstract：:The endogenous transcriptase present in purified vesicular stomatitis (VS) virions was solubilized with a Triton X-100 high-salt solution. The polymerase activity was purified on glycerol gradients and by phosphocellulose column chromatography; the viral proteins present in the active enzyme fractions were identified ...

journal_title：Journal of virology

authors： Emerson SU,Wagner RR

更新日期：1973-12-01 00:00:00

abstract：:Influenza A virus NS2 protein, also called nuclear export protein (NEP), is crucial for the nuclear export of viral ribonucleoproteins. However, the molecular mechanisms of NEP mediation in this process remain incompletely understood. A leucine-rich nuclear export signal (NES2) in NEP, located at the predicted N2 heli...

journal_title：Journal of virology

authors： Huang S,Chen J,Chen Q,Wang H,Yao Y,Chen J,Chen Z

更新日期：2013-01-01 00:00:00

abstract：:In varicella-zoster virus (VZV)-infected primary human brain vascular adventitial fibroblasts (BRAFs), levels of beta interferon (IFN-β,) STAT1, and STAT2 transcripts as well as STAT1 and STAT2 protein were decreased. IFN-α transcript levels were increased but not secreted IFN-α protein levels. Compared to IFN-α-treat...

journal_title：Journal of virology

authors： Nagel MA,James SF,Traktinskiy I,Wyborny A,Choe A,Rempel A,Baird NL,Gilden D

更新日期：2014-10-01 00:00:00

abstract：:Noninfectious spikeless particles have been obtained from vesicular stomatitis virus (VSV, Indiana serotype) by bromelain or Pronase treatment. They lack the viral glycoprotein (G) but contain all the other viral components (RNA, lipid, and other structural proteins). Triton-solubilized VSV-Indiana glycoprotein prepar...

journal_title：Journal of virology

authors： Bishop DH,Repik P,Obijeski JF,Moore NF,Wagner RR

更新日期：1975-07-01 00:00:00

abstract：:An important site for bovine herpesvirus 1 (BoHV-1) latency is sensory neurons within trigeminal ganglia (TG). The synthetic corticosteroid dexamethasone consistently induces BoHV-1 reactivation from latency. Expression of four Krüppel-like transcription factors (KLF), i.e., KLF4, KLF6, PLZF (promyelocytic leukemia zi...

journal_title：Journal of virology

authors： El-Mayet FS,Sawant L,Thunuguntla P,Zhao J,Jones C

更新日期：2020-01-31 00:00:00

abstract：:A vigorous expansion of antigen-specific CD8(+) T cells lacking apparent effector function was observed in a rhesus macaque acutely infected with the simian immunodeficiency virus (SIV) strain SIVmac239. Antigen-specific CD8(+) T cells were identified using antigenic-peptide class I major histocompatibility complex te...

journal_title：Journal of virology

authors： Xiong Y,Luscher MA,Altman JD,Hulsey M,Robinson HL,Ostrowski M,Barber BH,MacDonald KS

更新日期：2001-03-01 00:00:00

abstract：:Two virus-specific species of newly synthesized DNA were isolated from rat fibroblast cell cultures infected with the Kilham rat virus (RV). These two DNA species were purified; their behavior on hydroxyapatite chromatography and their sedimentation coefficients in sucrose gradients were determined. One of the two spe...

journal_title：Journal of virology

authors： Gunther M,May P

更新日期：1976-10-01 00:00:00

abstract：:Rodent fibroblasts infected with the ts371 Kirsten murine sarcoma virus (KiMuSV) are temperature sensitive for the maintenance of transformation because of the production of an abnormal p21 protein. We cloned the ts371 KiMuSV provirus from the genome of a conditionally transformed nonproducer cell line, ts371 KiMuSV N...

journal_title：Journal of virology

authors： Stein RB,Tai JY,Scolnick EM

更新日期：1986-11-01 00:00:00

abstract：:Herpes simplex virus type 1 packages its DNA genome into a precursor capsid, referred to as the procapsid. Of the three capsid-associated DNA-packaging proteins, UL17, UL25, and UL6, only UL17 and UL6 appear to be components of the procapsid, with UL25 being added subsequently. To determine whether the association of ...

journal_title：Journal of virology

authors： Thurlow JK,Murphy M,Stow ND,Preston VG

更新日期：2006-03-01 00:00:00