MR imaging with hyperpolarized 3He gas.

Abstract:

:Magnetic resonance images of the lungs of a guinea pig have been produced using hyperpolarized helium as the source of the MR signal. The resulting images are not yet sufficiently optimized to reveal fine structural detail within the lung, but the spectacular signal from this normally signal-deficient organ system offers great promise for eventual in vivo imaging experiments. Fast 2D and 3D GRASS sequences with very small flip angles were employed to conserve the norenewable longitudinal magnetization. We discuss various unique features associated with performing MRI with hyperpolarized gases, such as the selection of the noble gas species, polarization technique, and constraints on the MR pulse sequence.

journal_name

Magn Reson Med

authors

Middleton H,Black RD,Saam B,Cates GD,Cofer GP,Guenther R,Happer W,Hedlund LW,Johnson GA,Juvan K

doi

10.1002/mrm.1910330219

subject

Has Abstract,Author List Incomplete

pub_date

1995-02-01 00:00:00

pages

271-5

issue

2

eissn

0740-3194

issn

1522-2594

journal_volume

33

pub_type

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