Abstract：
BACKGROUND:Cardiovascular autonomic neuropathy (CAN) is rapidly growing in all populations worldwide. Baroreflex sensitivity (BRS) is easily applied as a diagnostic test to a large number of individuals in the general population. However, no study has reported the normal reference values of BRS for the CAN diagnostic test in a Chinese population. The aim of this study was to estimate the normative reference value of BRS, and assess CAN prevalence in our cross-sectional dataset. METHODS:We conducted a large-scale, community-based, cross-sectional study in a Chinese population. We performed data analysis on 2,092 subjects. Cardiovascular autonomic function was assessed using spontaneous BRS. A total of 349 healthy subjects were used to perform analysis for the reference value for BRS. The CAN prevalence was calculated in the overall sample, and in patients with diabetes mellitus, patients with hypertension and patients with metabolic syndrome. RESULTS:In the overall sample, the reference value for total power (TP.brs) was more than 1.96 ms/mmHg. The cut-off points of 1.74 ms/mmHg and 2.53 ms/mmHg were set as high frequency (HF.brs) and low frequency (LF.brs), respectively. CAN diagnostic tests based on the reference value were performed. The estimated CAN prevalence in the overall sample was 20.41% using the BRS test. CAN prevalence was 33.18%, 28.69% and 28.57% in patients with diabetes mellitus, patients with hypertension and patients with metabolic syndrome, respectively. CONCLUSIONS:Our findings provided reference values for BRS. Estimated CAN prevalence was high in this Chinese population, which has become a major public health problem in China.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Tang ZH,Zeng F,Ye K,Yu X,Zhou Ldoi
10.1186/2047-783X-19-8subject
Has Abstractpub_date
2014-02-12 00:00:00pages
8eissn
0949-2321issn
2047-783Xpii
2047-783X-19-8journal_volume
19pub_type
杂志文章abstract：:The authors report a large duodenal somatostatinoma, a very rare tumor entity. A 8.5 cm globular mass in the area of the unicate process of the pancreas was detected in a 45 year old caucasian female by computerized tomography. The patient had only mild complaints. Initial treatment consisted of right pancreatectomy w...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
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abstract：:In the absence of thromboprophylaxis, venous thromboembolism (VTE) affects about 50 to 80% of the patients after total hip replacement (THR), total knee replacement (TKR), or hip fracture surgery. Since stratification of patients in those who will become symptomatic and those who will not, is not possible, primary hig...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：
更新日期：2004-03-30 00:00:00
abstract：:Therapeutic options are limited for patients refractory to triple therapy with two reverse transcriptase inhibitors and one protease inhibitor. Preliminary results showing favorable effects of protease inhibitor combination therapy with nelfinavir and saquinavir due to inhibition of metabolism by cytochrome P450 (CYP4...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-02-25 00:00:00
abstract：:Triple A (four A; Allgrove syndrome) syndrome is a an autosomal recessive disorder characterized by alacrimia, achalasia, adrenocortical insufficiency, and various neurological abnormalities. We report a case of triple A syndrome in a 14-year-old female patient together with oral manifestations. The importance of this...
journal_title：European journal of medical research
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更新日期：2003-07-31 00:00:00
abstract：OBJECTIVE:To report on radiological and epidemiological characteristics of pulmonary disease in patients with HIV infection in times of highly active antiretroviral therapy (HAART). METHODS:Clinical data of 130 HIV infected adults with acute pulmonary symptoms were compared with findings in chest radiography (n = 130)...
journal_title：European journal of medical research
pub_type： 杂志文章
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更新日期：2007-08-16 00:00:00
abstract：OBJECTIVE:replication of HIV-1 after cell entry is essentially dependent on the reverse transcriptase (RT). Antiretroviral drugs impairing the function of the RT currently aim at the polymerase subunit. One reason for failure of antiretroviral treatment is the evolvement of resistance-associated mutations in the viral ...
journal_title：European journal of medical research
pub_type： 杂志文章
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journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-15-3-135
更新日期：2010-03-30 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 杂志文章
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更新日期：2005-11-16 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2000-08-18 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章
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更新日期：1998-07-20 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章
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更新日期：2009-09-01 00:00:00
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更新日期：2001-06-28 00:00:00
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journal_title：European journal of medical research
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更新日期：2016-01-09 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章,评审
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更新日期：1997-02-21 00:00:00
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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更新日期：1997-04-21 00:00:00
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更新日期：2019-01-28 00:00:00
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journal_title：European journal of medical research
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更新日期：2001-04-20 00:00:00
