Abstract：
:Endorectal ultrasonography (ERUS) and magnetic resonance imaging (MRI) allow exploring the morphology of the rectum in detail. Use of such data, especially assessment of the rectal wall, is an important tool for ascertaining the perianal fistula localization as well as stage of the cancer and planning it appropriate treatment, as stage T3 tumors are usually treated with neoadjuvant therapy, whereas T2 tumors are initially managed surgically. The only advantage of ERUS over MRI is the possibility of assessing T1 tumors that could be treated by transanal endoscopic microsurgery. However, MRI is better for visualizing most radiological prognostic features in rectal or anal cancer such as a circumferential resection margin less than 1 mm, T stage at T1-T2 or T3 tumors with extramural extension less than 5 mm, absence of extramural vascular invasion, N stage at N0/N1, and tumors located in the middle or upper third of the rectum. It can also evaluate the intersphincteric space or levator ani muscle involvement. Increased signal on diffusion weighted imaging (DWI) and low apparent diffusion coefficient (ADC) values as well as an irregular contour and heterogeneous internal signal intensity seem to predict the involvement of pelvic lymphatic nodes better than their size alone. Computed tomography as well as other examination techniques, including digital rectal examination, contrast edema, recto- and colonoscopy, are less useful in staging of rectal cancer but still are very important screening tools.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Burdan F,Sudol-Szopinska I,Staroslawska E,Kolodziejczak M,Klepacz R,Mocarska A,Caban M,Zelazowska-Cieslinska I,Szumilo Jdoi
10.1186/s40001-014-0078-0subject
Has Abstractpub_date
2015-01-14 00:00:00pages
4eissn
0949-2321issn
2047-783Xpii
s40001-014-0078-0journal_volume
20pub_type
杂志文章,评审abstract：BACKGROUND:A great variety of dental materials are now available for use in restorative treatments. Much attention has been devoted to physical and chemical properties, but the biological effects of these materials have been less frequently studied. AIM:The aim of this study is to test the influence of resin based res...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2001-10-29 00:00:00
abstract：:Experiments in space have shown that T lymphocyte function is altered in more than 50% of space crew members. There is strong evidence that such effect is due to stress rather than to weightlessness per se. However the health of astronauts was never threatened so far. Experiments in-vitro with cultures of human periph...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1999-09-09 00:00:00
abstract：BACKGROUND:The pathogenesis of central retinal artery occlusions (CRAO) varies, depending upon the underlying disease. An embolic origin of an occlusion often occurs. PATIENT AND METHODS:A 50-year-old man with an occlusion of the left internal carotid artery was examined because of a left central retinal artery occlus...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2000-04-19 00:00:00
abstract：BACKGROUND:Patients with human immunodeficiency virus (HIV) infection have an increased risk of cardiovascular diseases. Previous publications described pericardial effusion as one of the most common HIV-associated cardiac affiliations. The aim of the current study was to investigate if pericardial effusion still has a...
journal_title：European journal of medical research
pub_type： 杂志文章,多中心研究
doi：10.1186/2047-783x-16-11-480
更新日期：2011-11-10 00:00:00
abstract：BACKGROUND:Acute lung injury (ALI) is a serious clinical syndrome with a high rate of mortality. In this study, the effects of triptolide on lipopolysaccharide (LPS)-induced ALI in rats were investigated. METHODS:Sixty-five male Sprague Dawley rats(approved by ethics committee of the First Affiliated Hospital of Sooch...
journal_title：European journal of medical research
pub_type： 杂志文章,收录出版
doi：10.1186/2047-783X-18-58
更新日期：2013-12-17 00:00:00
abstract：BACKGROUND:Osteoporosis affects 200 million people worldwide and places an enormous economic burden on society. We aim to identify the feature genes that are related to osteoprotegerin in osteoporosis and to perform function analysis with DNA microarray from human bone marrow. METHODS:We downloaded the gene expression...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783X-18-15
更新日期：2013-06-03 00:00:00
abstract：:The influence of heparin on Polymorphonuclear (PMN s) leukocytes was investigated using a new whole-blood cytofluorometric method (patent granted for the test with the number P 4334935.8-41) with Candida albicans and Staphylococcus aureus as test microorganisms. After comparing the effect of equal volumes of two widel...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1997-12-31 00:00:00
abstract：:HIV-1 protease inhibitors have contributed significantly to the reduction in morbidity and mortality associated with HIV-1 disease. Some of their clinical benefit may be attributed to inhibition of non-viral pathogen proteases and mammalian proteases involved in apoptosis. Our objective was to investigate the effect o...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2003-01-28 00:00:00
abstract：:In Germany during the past years about 200-250 HIV infected pregnant women delivered a baby per year, a number that is currently increasing. To determine the HIV-status early in pregnancy voluntary HIV-testing of all pregnant women is recommended in Germany and Austria as part of prenatal care. In those cases, where H...
journal_title：European journal of medical research
pub_type： 共识发展会议,杂志文章,评审
doi：
更新日期：2004-06-30 00:00:00
abstract：OBJECTIVES:Several epidemiological studies address psychosomatic self regulation as a measure of quality of life aspects. However, although widely used in studies with a focus on complementary cancer treatment, and recognized to be associated with better survival of cancer patients, it is unclear what the self regulati...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-14-5-223
更新日期：2009-05-14 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the impact of diosgenin, an important monomer of sapogenins in yams, on ovarian reserve in a natural aging mice model. STUDY DESIGN:This randomized controlled trial included 60 9-month-old C57 naturally aging female mice. Twenty-one mice were assigned to the dio grou...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-017-0285-6
更新日期：2017-10-18 00:00:00
abstract：:A fifty-year-old female presented with a one month history of progressive dyspnea, productive cough, pain of elbows and knees, and 40°C fever despite antibiotic treatment. She has been diagnosed of bronchial asthma over 25 years before admission and oral and depot glucocorticosteroids as a long-term therapy was applie...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-15-s2-92
更新日期：2010-11-04 00:00:00
abstract：BACKGROUND:The purpose was to explore possible risk factors of facet joint violation induced by adjacent superior vertebral pedicle screw during the minimally invasive surgery transforaminal lumbar interbody fusion (MIS-TLIF). METHODS:A total of 69 patients with lumbar degenerative disease, who underwent MIS-TLIF were...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-015-0174-9
更新日期：2015-09-24 00:00:00
abstract：BACKGROUND:Multiple severe trauma frequently leads to massive dysbalances of the human immune system. This phenomenon is known as "Systemic Inflammatory Response Syndrome (SIRS)". SIRS is connected to multiple organ failure and thereby entails higher morbidity and mortality in trauma patients. Pro- and anti-inflammator...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-14-7-284
更新日期：2009-07-22 00:00:00
abstract：BACKGROUND:The purpose of this study was to assess the association between leisure-time physical activity (LPA) and the risk of metabolic syndrome (MS). METHODS:Prospective cohort studies of the association between LPA and the risk of MS were retrieved from the PubMed and Embase databases up to 12 August 2013. The sta...
journal_title：European journal of medical research
pub_type： 杂志文章,meta分析,收录出版
doi：10.1186/2047-783X-19-22
更新日期：2014-04-23 00:00:00
abstract：:Among primary hepatic malignancies, sarcomas represent a minority of 2 %. Of those, primary hepatic angiosarcoma is the most common one. In the past its incidence has been related to the exposure of certain chemicals like thorotrast, vinyl-chloride or arsenic. - Patients suffering from this aggressive, highly vascular...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2007-12-14 00:00:00
abstract：:Long-term pneumotachographic measurements in newborns are hampered by the apparatus dead space, which can be functionally eliminated by a constant bias flow (flow-through technique). In a clinical study the influence of this bias flow was investigated. - In 80 infants (group 1:20 healthy controls, group 2: 30 infants ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1999-01-26 00:00:00
abstract：OBJECTIVE:The study investigated the feasibility and potential outcome measures during acute hyperoxia in type 2 diabetes patients (DM2). METHODS:Eleven DM2 patients (7 men and 4 women) were included in the study. The patients cycled (30 min at 20% Wmax) whilst breathing three different supplemental oxygen flows (SOF,...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-015-0194-5
更新日期：2016-01-08 00:00:00
abstract：:In the treatment of pulmonary diseases the inhalation of aerosols plays a key role - it is the preferred route of drug delivery in asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. But, in contrast to oral and intravenous administration drug delivery to the lungs is controlled by additional par...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：10.1186/2047-783x-14-s4-71
更新日期：2009-12-07 00:00:00
abstract：INTRODUCTION:Mitochondrial dysfunction plays a central role in the general pathogenesis of non-alcoholic fatty liver disease (NAFLD), increasing the risk of developing steatosis and subsequent hepatocellular inflammation. We aimed to assess hepatic mitochondrial function by a non-invasive (13)C-methionine breath test (...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-16-6-258
更新日期：2011-06-21 00:00:00
abstract：BACKGROUND:Processes of restenosis, following arterial injury, are complex involving different cell types producing various cytokines and enzymes. Among those enzymes, smooth muscle cell-derived matrix metalloproteinases (MMPs) are thought to take part in cell migration, degrading of extracellular matrix, and neointima...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-15-11-461
更新日期：2010-11-25 00:00:00
abstract：BACKGROUND:Ceftriaxone is commonly used as an alternative antibiotic drug in treating syphilis but clinical data on its efficacy are limited. OBJECTIVE:To evaluate the response of HIV-infected patients with active syphilis to treatment with penicillin or ceftriaxone. - METHODS:A retrospective study involving 24 conse...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-16-2-47
更新日期：2011-02-24 00:00:00
abstract：:Right ventricle (RV) dysfunction is a key outcome determinant and a leading cause of death for patients with chronic thromboembolic pulmonary hypertension (CTEPH). In this report, we followed the 5-year clinical journey of a patient with CTEPH. The tricuspid pressure gradient was significantly increased in the early p...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-015-0112-x
更新日期：2015-03-02 00:00:00
abstract：BACKGROUND:The current pilot study compares the impact of an intravenous infusion of Ringer's lactate to an acetate-based solution with regard to acid-base balance. The study design included the variables of the Stewart approach and focused on the effective strong ion difference. Because adverse hemodynamic effects hav...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783X-17-21
更新日期：2012-07-06 00:00:00
abstract：:Triple A (four A; Allgrove syndrome) syndrome is a an autosomal recessive disorder characterized by alacrimia, achalasia, adrenocortical insufficiency, and various neurological abnormalities. We report a case of triple A syndrome in a 14-year-old female patient together with oral manifestations. The importance of this...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2003-07-31 00:00:00
abstract：:Targeted intrapulmonary delivery of drugs may reduce systemic toxicity, improve treatment efficacy, but inhaled drugs may also interfere with pulmonary surfactant function. We hypothesized that the lipophilic drug amphotericin B used to treat or prevent pulmonary infections with aspergillus species, might destroy surf...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1998-08-18 00:00:00
abstract：:Severe pulmonary hypertension is a lethal group of disorders which preferentially afflicts women. It appears that in recent years the patient profile has shifted towards older, obese, and postmenopausal women, suggesting that endocrine factors may be important. Several studies have revealed an increased prevalence of ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-14-10-433
更新日期：2009-09-28 00:00:00
abstract：OBJECTIVE:Evaluating the effects of prophylactic administration of IgM-enriched immunoglobulins (IVIG) on immunological- and clinical parameters in cardiac surgical patients. PATIENTS AND METHODS:41 patients were randomized to receive either an IgM-enriched immunoglobulin (Pentaglobin(R)) preparation (1,300 ml immunog...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2002-12-17 00:00:00
abstract：BACKGROUND:Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is a congenital, non-progressive autosomal-dominant disorder with bilateral oculomotor nerve palsy due to mutations in the kinesin motor protein gene KIF21A. - RESULTS:We present a 60-year old patient with CFEOM1 due to the common C2860T mutatio...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2005-08-17 00:00:00
abstract：:We investigated the expression pattern of Jagged1 peptide in mandibular condylar cartilage, as a type of secondary cartilage. Mandibular condyle of ddY mice were fixed from embryonic day 15 (E15) through just after birth (equivalent to E19). Serial sections were examined using histological immunohistochemical (IHC) te...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2008-01-23 00:00:00
