Abstract:
:Right ventricle (RV) dysfunction is a key outcome determinant and a leading cause of death for patients with chronic thromboembolic pulmonary hypertension (CTEPH). In this report, we followed the 5-year clinical journey of a patient with CTEPH. The tricuspid pressure gradient was significantly increased in the early phase of CTEPH and "normalized" at the late phase of this patient's clinical journey, but this "normalized" gradient is not a positive treatment response but rather an ominous sign of advancing right heart failure owing to an exhaustion of RV contractile function. Thus, appropriate interpretation of the tricuspid pressure gradient change is of importance for assessing RV dysfunction and treatment outcome during follow-up in patients with CTEPH. Besides systolic pulmonary artery pressure (SPAP), other RV functional parameters such as tricuspid annular plane systolic excursion, RV fractional area change, and RV longitudinal strain, together with clinical markers, may provide additional guidance regarding functional improvement or progression in patients with CTEPH.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Liu D,Hu K,Pelzer HT,Störk S,Weidemann Fdoi
10.1186/s40001-015-0112-xsubject
Has Abstractpub_date
2015-03-02 00:00:00pages
20eissn
0949-2321issn
2047-783Xpii
10.1186/s40001-015-0112-xjournal_volume
20pub_type
杂志文章abstract:BACKGROUND:Resternotomy in cardiac surgery is considered a risk factor for postoperative complications. Previous studies have demonstrated an ambiguous relationship between resternotomy and clinical outcomes. Registry data from a mixed population of durable circulatory support devices suggest that history of cardiac su...
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journal_title:European journal of medical research
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-01-29 00:00:00
abstract::Polyadenosylation of nuclear enzymes is well known to regulate the cellular repair capacity after DNA damage. PARP mediates the transfer of poly-ADP-ribose moieties on itself and other nuclear proteins by the breakdown of NAD+. The present study investigated how modulation of PARP activity interferes with cell death i...
journal_title:European journal of medical research
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journal_title:European journal of medical research
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journal_title:European journal of medical research
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journal_title:European journal of medical research
pub_type: 杂志文章
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journal_title:European journal of medical research
pub_type: 杂志文章,评审
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journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783X-17-21
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journal_title:European journal of medical research
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journal_title:European journal of medical research
pub_type: 杂志文章,多中心研究
doi:10.1186/s40001-017-0277-6
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journal_title:European journal of medical research
pub_type: 杂志文章
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journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-15-2-84
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journal_title:European journal of medical research
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-11-17 00:00:00
abstract::Long-term pneumotachographic measurements in newborns are hampered by the apparatus dead space, which can be functionally eliminated by a constant bias flow (flow-through technique). In a clinical study the influence of this bias flow was investigated. - In 80 infants (group 1:20 healthy controls, group 2: 30 infants ...
journal_title:European journal of medical research
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journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2002-09-30 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:10.1186/2047-783x-14-s4-71
更新日期:2009-12-07 00:00:00
abstract:OBJECTIVE:To report on radiological and epidemiological characteristics of pulmonary disease in patients with HIV infection in times of highly active antiretroviral therapy (HAART). METHODS:Clinical data of 130 HIV infected adults with acute pulmonary symptoms were compared with findings in chest radiography (n = 130)...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2007-08-16 00:00:00
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journal_title:European journal of medical research
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journal_title:European journal of medical research
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journal_title:European journal of medical research
pub_type: 杂志文章,评审
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journal_title:European journal of medical research
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journal_title:European journal of medical research
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journal_title:European journal of medical research
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更新日期:2000-03-27 00:00:00
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journal_title:European journal of medical research
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journal_title:European journal of medical research
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