Abstract:
:Among primary hepatic malignancies, sarcomas represent a minority of 2 %. Of those, primary hepatic angiosarcoma is the most common one. In the past its incidence has been related to the exposure of certain chemicals like thorotrast, vinyl-chloride or arsenic. - Patients suffering from this aggressive, highly vascular tumor have a poor prognosis in general. Without treatment most of them die after rapid tumor progression with multifocal dissemination. In case of tumor perforation, fatal abdominal hemorrhage has been observed. - We herein report the successful interdisciplinary treatment of an 81 year-old woman with a perforated primary hepatic angiosarcoma of the left hepatic lobe. Initially, tumor bleeding was stopped by emergency interventional coil embolization. After stabilization of the patient, we performed an elective tumor resection. The patient could eventually be discharged in a good clinical condition. - So far, no standard therapy has established for patients with primary hepatic angiosarcoma. Surgery seems to be the treatment of choice. In addition, preoperative interventional embolization of the tumor supplying vessels reduces the risk of pre- and intraoperative bleeding. The value of adjuvant chemotherapy is not yet clarified. - The outcome of most patients with primary hepatic angiosarcoma remains poor and there is a need for clinical studies.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Matthaei H,Boelke E,Eisenberger CF,Alldinger I,Krieg A,Schmelzle M,Poremba C,Schellhammer F,Knoefel WT,Budach W,Peiper Msubject
Has Abstractpub_date
2007-12-14 00:00:00pages
591-4issue
12eissn
0949-2321issn
2047-783Xjournal_volume
12pub_type
杂志文章abstract:BACKGROUND:Breast cancer risk prediction models are widely used in clinical settings. Although most of the well-known models were designed based on data collected from western population, yet they have been utilized for surveillance purposes in many limited-resource countries. Given the genetic variations in risk facto...
journal_title:European journal of medical research
pub_type: 杂志文章,多中心研究
doi:10.1186/s40001-017-0277-6
更新日期:2017-09-29 00:00:00
abstract::In ten cystic fibrosis patients and nine age-matched controls, renal function was determined before and after infusion of secretin. Under baseline conditions creatinine excretion and clearance were significantly elevated, exclusively due to those patients who were homozygous for the DF508 mutation (153 vs 132 ml/min*1...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-10-30 00:00:00
abstract::The introduction of integrase inhibitors as a new drug class for treatment of HIV have added a very potent and extremely well tolerated new treatment option to the HIV-armentarium. Particularly in patients with previously developed drug resistance, the availability of new active drugs offers great hope. Moreover, the ...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:10.1186/2047-783x-14-s3-1
更新日期:2009-11-24 00:00:00
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journal_title:European journal of medical research
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abstract:BACKGROUND:Systemic treatment of head and neck squamous cell carcinoma (HNSCC) includes a variety of antineoplastic drugs. However, drug-resistance interferes with the effectiveness of chemotherapy. Preclinical testing models are needed in order to develop approaches to overcome chemoresistance. - METHODS:Ten human ce...
journal_title:European journal of medical research
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doi:10.1186/2047-783X-18-23
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journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783X-18-43
更新日期:2013-11-14 00:00:00
abstract::Long-term pneumotachographic measurements in newborns are hampered by the apparatus dead space, which can be functionally eliminated by a constant bias flow (flow-through technique). In a clinical study the influence of this bias flow was investigated. - In 80 infants (group 1:20 healthy controls, group 2: 30 infants ...
journal_title:European journal of medical research
pub_type: 杂志文章
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更新日期:1999-01-26 00:00:00
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更新日期:2008-07-28 00:00:00
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journal_title:European journal of medical research
pub_type: 共识发展会议,杂志文章,评审
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更新日期:2004-06-30 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2006-06-30 00:00:00
abstract::Gadolinium chelates are widely used in magnetic resonance imaging as contrast medium in patients with nephropathy. However, only few studies have investigated the effect of gadolinium on serum creatinine concentration and estimated GFR as surrogate markers of renal function. This study was performed to evaluate the ef...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2005-04-20 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章,评审
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更新日期:1997-02-21 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-15-5-210
更新日期:2010-05-18 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章
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更新日期:1999-09-09 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章,评审
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更新日期:2015-01-14 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783X-17-7
更新日期:2012-04-17 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章
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更新日期:2002-02-21 00:00:00
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journal_title:European journal of medical research
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journal_title:European journal of medical research
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更新日期:2003-07-31 00:00:00
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journal_title:European journal of medical research
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更新日期:2006-04-28 00:00:00
abstract::A 65-year old woman with known history of reactive depression and failed suicide attempts ingested 7 mg digitoxin at 09.00 h. After vomiting 4 hours later, she reported the drug intake to her husband who thereupon summoned a physician. Arriving at 16.00 h, the physician was informed about the suicide attempt, but fail...
journal_title:European journal of medical research
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更新日期:1996-11-25 00:00:00
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journal_title:European journal of medical research
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doi:10.1186/2047-783x-16-8-375
更新日期:2011-08-08 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章
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更新日期:1997-03-24 00:00:00
abstract:AIM:Antiseptics are commonly used in clinical practice to disinfect tissue and to avoid infections. However, topical antiseptics are assumed to have an influence on skin microcirculation, per se. Thus, the aim of the study was to analyse the influence of topically applied antiseptics on the microcirculation of intact s...
journal_title:European journal of medical research
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journal_title:European journal of medical research
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更新日期:2007-03-26 00:00:00
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journal_title:European journal of medical research
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更新日期:2005-03-29 00:00:00