Abstract:
:We have previously demonstrated the ability of UVC (254 nm) radiation to induce asynchronous polyoma replication in rat fibroblast cells (H3 line) that contain an integrated copy of polyoma virus. In the present study we show that general purpose lamps can induce polyoma replication in these cells as well. The amount of UV radiation emitted by three different light sources was determined and the effects of each source on the replication of polyoma DNA was assessed. Our findings indicate that a 100 W incandescent lamp had a minimal effect on replication, whereas a 90 s exposure to a halogen lamp or a 160 W mercury vapor lamp induced replication 1.5-fold and 2-fold, respectively, in comparison with nontreated controls. We have previously shown that asynchronous polyoma replication in H3 cells involves UV-inducible cellular protein factors. Our present results indicate that these factors are also activated by exposure to commonly used lamps that emit comparable doses of UV radiation.
journal_name
Photochem Photobioljournal_title
Photochemistry and photobiologyauthors
Rutberg SE,Ronai Zdoi
10.1111/j.1751-1097.1993.tb09559.xsubject
Has Abstractpub_date
1993-08-01 00:00:00pages
265-9issue
2eissn
0031-8655issn
1751-1097journal_volume
58pub_type
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journal_title:Photochemistry and photobiology
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Photochemistry and photobiology
pub_type: 杂志文章,评审
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