Ideal cardiovascular health and the prevalence and progression of coronary artery calcification in adults with and without type 1 diabetes.

abstract：OBJECTIVE:To study determinants of incident hyperglycemia in rural Indian mothers 6 years after delivery. RESEARCH DESIGN AND METHODS:The Pune Maternal Nutrition Study collected information in six villages near Pune on prepregnant characteristics and nutrition, physical activity, and glucose tolerance during pregnancy...

journal_title：Diabetes care

authors： Kulkarni SR,Fall CH,Joshi NV,Lubree HG,Deshpande VU,Pasarkar RV,Bhat DS,Naik SS,Yajnik CS

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between the genetic polymorphisms of PPARgamma (Pro12Ala, C1431T, and C-2821T) and the risk of ischemic stroke and to investigate whether these genetic polymorphisms of PPARgamma would modify the risk of ischemic stroke among patients with hypertension or diabetes. RESEARCH DESIGN...

journal_title：Diabetes care

authors： Hsieh FI,Lo WC,Lin HJ,Hsieh YC,Lien LM,Bai CH,Tseng HP,Chiou HY

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To investigate the metabolic effects of metformin, as compared with placebo, in type 2 diabetic patients intensively treated with insulin. RESEARCH DESIGN AND METHODS:Metformin improves glycemic control in poorly controlled type 2 diabetic patients. Its effect in type 2 diabetic patients who are intensively ...

journal_title：Diabetes care

authors： Wulffelé MG,Kooy A,Lehert P,Bets D,Ogterop JC,Borger van der Burg B,Donker AJ,Stehouwer CD

更新日期：2002-12-01 00:00:00

abstract：:A 51-yr-old, nonobese, male patient presented with hyperglycemia and a recent 40-pound weight loss. Severe insulin resistance was documented in studies in which high amounts of insulin were infused using the Biostator GCIIS. Diabetic control was finally achieved with subcutaneous injections of 470 U of insulin per day...

journal_title：Diabetes care

authors： Baldwin D Jr,Winston E,Hoshizaki RJ,Garland JT,Baldwin D Sr,Holcomb HH,Flier JS,Rubenstein A

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To explore the possible link between diabetic nephropathy and the enhanced activity of the polyol pathway, known to occur in IDDM subjects. RESEARCH DESIGN AND METHODS:We studied the effects of the aldose reductase inhibitor tolrestat (200 mg/day) on urinary albumin excretion rate and glomerular filtration r...

journal_title：Diabetes care

authors： Passariello N,Sepe J,Marrazzo G,De Cicco A,Peluso A,Pisano MC,Sgambato S,Tesauro P,D'Onofrio F

更新日期：1993-05-01 00:00:00

abstract：:Borderline hypertension, a condition in which the blood pressure oscillates between normal and high values, is a predictor of future more severe hypertension. Pathophysiologically, borderline hypertension is different from established hypertension. A large proportion of such patients have elevated cardiac output and a...

journal_title：Diabetes care

authors： Julius S

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVE:To determine whether adults diagnosed with type 2 diabetes from age 18 to 44 years more aggressively develop clinical complications after diagnosis than adults diagnosed at >or=45 years of age. RESEARCH DESIGN AND METHODS:We compared outcomes among 7844 adults in a health maintenance organization who were ne...

journal_title：Diabetes care

authors： Hillier TA,Pedula KL

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:Interleukin (IL)-18 is a proinflammatory cytokine secreted from mononuclear cells. Serum concentration of IL-18 is a strong predictor of death in patients with cardiovascular diseases. Recent studies have shown that microinflammation is involved in the pathogenesis of diabetic nephropathy as well as of cardio...

journal_title：Diabetes care

authors： Nakamura A,Shikata K,Hiramatsu M,Nakatou T,Kitamura T,Wada J,Itoshima T,Makino H

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the relative value of plasma glucose (PG) at different time points in assessing glucose control of type 2 diabetic patients. RESEARCH DESIGN AND METHODS:Glycemic profiles, i.e., PG at prebreakfast (8:00 A.M.), prelunch (11:00 A.M.), postlunch (2:00 P.M.), and extended postlunch (5:00 P.M.) times ...

journal_title：Diabetes care

authors： Avignon A,Radauceanu A,Monnier L

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To compare the effect of morning and bedtime NPH insulin combined with daytime sulfonylurea on glycemic control in non-insulin-dependent diabetes mellitus (NIDDM) patients no longer responding to treatment with sulfonylureas alone. RESEARCH DESIGN AND METHODS:Twenty-four NIDDM patients who fulfilled these cr...

journal_title：Diabetes care

authors： Groop LC,Widén E,Ekstrand A,Saloranta C,Franssila-Kallunki A,Schalin-Jäntti C,Eriksson JG

更新日期：1992-07-01 00:00:00

abstract：:Malfunction of portable continuous subcutaneous insulin infusion (CSII) systems may result in either ketoacidosis or serious hypoglycemia. To determine the types and frequencies of infusion system failure and the resulting clinical consequences, we recorded their occurrences in a 1-yr prospective study of 127 patients...

journal_title：Diabetes care

authors： Mecklenburg RS,Guinn TS,Sannar CA,Blumenstein BA

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:Little evidence exists regarding long-term diet quality and the risk of type 2 diabetes among Asian populations, who have undergone a nutrition transition and a diabetes epidemic. RESEARCH DESIGN AND METHODS:A total of 117,919 Chinese men and women, 40-74 years old, free of diabetes, cardiovascular disease, ...

journal_title：Diabetes care

authors： Yu D,Zheng W,Cai H,Xiang YB,Li H,Gao YT,Shu XO

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Acarbose inhibits alpha-glucosidases of the small intestine and thus delays glucose release from complex carbohydrates. Therefore, its efficacy and acceptability as a first-line drug in non-insulin-dependent diabetes mellitus (NIDDM) insufficiently treated with diet alone was tested in a randomized double-bli...

journal_title：Diabetes care

authors： Hanefeld M,Fischer S,Schulze J,Spengler M,Wargenau M,Schollberg K,Fücker K

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:The relative roles of insulin resistance and beta-cell dysfunction in the pathogenesis of impaired glucose tolerance (IGT) and type 2 diabetes are debated. First-degree relatives of individuals with type 2 diabetes are at increased risk of developing hyperglycemia. RESEARCH DESIGN AND METHODS:We evaluated th...

journal_title：Diabetes care

authors： Cnop M,Vidal J,Hull RL,Utzschneider KM,Carr DB,Schraw T,Scherer PE,Boyko EJ,Fujimoto WY,Kahn SE

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To compare blood glucose control and incidence of nocturnal hypoglycemia in adolescents with type 1 diabetes on multiple injection regimens managed with either an insulin analog combination or NPH insulin plus regular human insulin. RESEARCH DESIGN AND METHODS:In a randomized cross-over study, 28 adolescents...

journal_title：Diabetes care

authors： Murphy NP,Keane SM,Ong KK,Ford-Adams M,Edge JA,Acerini CL,Dunger DB

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To identify the clinical and genetic factors that explain why the rate of diabetes progression is highly variable between individuals following diagnosis of type 2 diabetes. RESEARCH DESIGN AND METHODS:We studied 5,250 patients with type 2 diabetes using comprehensive electronic medical records in Tayside, S...

journal_title：Diabetes care

authors： Zhou K,Donnelly LA,Morris AD,Franks PW,Jennison C,Palmer CN,Pearson ER

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Repaglinide is a newly developed oral blood glucose-lowering agent that exerts its effect by stimulating insulin secretion. This multicenter study was designed to compare the efficacy and safety of this drug with glyburide in a 1-year randomized double-blind study of outpatients with type 2 diabetes. RESEARC...

journal_title：Diabetes care

authors： Wolffenbuttel BH,Landgraf R

更新日期：1999-03-01 00:00:00

abstract：:OBJECTIVE To examine the use of mammography and Papanicolaou (Pap) smear among women with diabetes and to identify predictors of adherence to these tests. RESEARCH DESIGN AND METHODS We analyzed data of a nationally representative sample of Spanish women. Diabetes status was self-reported. Screenings were assessed ask...

journal_title：Diabetes care

authors： Jiménez-Garcia R,Hernandez-Barrera V,Carrasco-Garrido P,Gil A

更新日期：2009-08-01 00:00:00

abstract：:Two insulin-dependent diabetic subjects treated with pork and beef insulin during a period of 6 mo developed severe local reactions. Both patients had an important allergic history (asthma, urticaria, drug reactions, rhinitis). Skin-testing revealed type I allergy to beef and pork insulin. Specific IgE-insulin binding...

journal_title：Diabetes care

authors： De Leeuw I,Delvigne C,Bekaert J

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:Impaired awareness of hypoglycemia (IAH) and recurrent severe hypoglycemia (RSH) remain problematic for people with type 1 diabetes (T1D), despite major therapeutic advances. We explored beliefs around hypo- and hyperglycemia in adults with T1D with, and without, IAH and RSH. RESEARCH DESIGN AND METHODS:A cr...

journal_title：Diabetes care

authors： Cook AJ,DuBose SN,Foster N,Smith EL,Wu M,Margiotta G,Rickels MR,Speight J,de Zoysa N,Amiel SA

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:In patients with type 2 diabetes and cardiovascular diseases (CVDs), intensive treatment with insulin and/or sulfonylurea (SU) may be associated with excessive increased risk of hypoglycemic episodes. To evaluate the risk of critical arrhythmias related to glycemic variability, we carried out an observational...

journal_title：Diabetes care

authors： Stahn A,Pistrosch F,Ganz X,Teige M,Koehler C,Bornstein S,Hanefeld M

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To determine on a large scale the multiple medical and nonmedical factors that influence glycemic control in the general population of children with diabetes, we performed a nationwide French cross-sectional study. RESEARCH DESIGN AND METHODS:We enrolled 2,579 patients aged 1-19 years with type 1 diabetes of...

journal_title：Diabetes care

authors： Rosilio M,Cotton JB,Wieliczko MC,Gendrault B,Carel JC,Couvaras O,Ser N,Gillet P,Soskin S,Garandeau P,Stuckens C,Le Luyer B,Jos J,Bony-Trifunovic H,Bertrand AM,Leturcq F,Lafuma A,French Pediatric Diabetes Group,Bougnèr

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:To assess the prognostic role of ambulatory 24-h pulse pressure (PP) on various vascular events in relatively young type 2 diabetic subjects under 60 years of age. RESEARCH DESIGN AND METHODS:In this prospective study, 237 type 2 diabetic subjects without any history of vascular complications were analyzed. ...

journal_title：Diabetes care

authors： Nakano S,Konishi K,Furuya K,Uehara K,Nishizawa M,Nakagawa A,Kigoshi T,Uchida K

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To estimate the health-related quality of life (HRQOL) and treatment satisfaction for patients with type 2 diabetes in the Netherlands and to examine which patient characteristics are associated with quality of life and treatment satisfaction. RESEARCH DESIGN AND METHODS:For a sample of 1,348 type 2 diabetes...

journal_title：Diabetes care

authors： Redekop WK,Koopmanschap MA,Stolk RP,Rutten GE,Wolffenbuttel BH,Niessen LW

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Many studies have shown that diabetes increases the risk of cardiovascular disease (CVD) in women to a greater extent than in men. One explanation could be that diabetes has more adverse effects on CVD risk factors in women than in men. We compared diabetes-associated differences in CVD risk factors in men an...

journal_title：Diabetes care

authors： Howard BV,Cowan LD,Go O,Welty TK,Robbins DC,Lee ET

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:This study was performed to determine the net effects of euglycemia, resolution of renal failure, immunosuppressant drugs, and hyperinsulinemia on fasting lipid profiles of patients with renal failure and insulin-dependent diabetes mellitus (IDDM) after combined pancreas-kidney transplantation (PKT). RESEARC...

journal_title：Diabetes care

authors： Larsen JL,Stratta RJ,Ozaki CF,Taylor RJ,Miller SA,Duckworth WC

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To investigate the role of hyperglycemia in mediating the clinical association of NIDDM with hypertension and left ventricular dysfunction and hypertrophy. RESEARCH DESIGN AND METHODS:Since hyperglycemia elevates cytosolic free calcium (Cai) both in myocardial and vascular smooth muscle cells, we utilized nu...

journal_title：Diabetes care

authors： Barbagallo M,Gupta RK,Resnick LM

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:To determine whether the severity of retinopathy is higher in a group of NIDDM patients with sBP greater than or equal to 140 mmHg compared with NIDDM patients with sBP less than 140 mmHg. RESEARCH DESIGN AND METHODS:Ophthalmoscopy and FAG were conducted among a group of NIDDM patients with either a sBP abov...

journal_title：Diabetes care

authors： Cignarelli M,De Cicco ML,Damato A,Paternostro A,Pagliarini S,Santoro S,Cardia L,De Pergola G,Giorgino R

更新日期：1992-08-01 00:00:00

abstract：:Given the importance of glycemic control in the development of diabetes complications, the plethora of tools now available to monitor the day-to-day trends in glycemia is remarkable. In this regard, self-monitoring of blood glucose (SMBG) has been considered a key component of patient management. Arguably, there remai...

journal_title：Diabetes care

authors： Polonsky WH,Fisher L

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Platelet hyperfunction is a typical feature of the prothrombotic state that frequently complicates the natural history of diabetes. In uremia, a bleeding diathesis is present, which principally involves the primary phase of hemostasis. Thus, in patients with uremia of diabetic origin, the infrequent coexisten...

journal_title：Diabetes care

authors： Vicari AM,Taglietti MV,Pellegatta F,Spotti D,Melandri M,Galli L,Ronchi P,Folli F

更新日期：1996-10-01 00:00:00