High systolic blood pressure increases prevalence and severity of retinopathy in NIDDM patients.

abstract：OBJECTIVE:To investigate factors associated with bone mineral density (BMD) in type 1 diabetes by classic statistic and artificial neural networks. RESEARCH DESIGN AND METHODS:A total of 175 eugonadal type 1 diabetic patients (age 32.8 ± 8.4 years) and 151 age- and BMI-matched control subjects (age 32.6 ± 4.5 years) w...

journal_title：Diabetes care

authors： Eller-Vainicher C,Zhukouskaya VV,Tolkachev YV,Koritko SS,Cairoli E,Grossi E,Beck-Peccoz P,Chiodini I,Shepelkevich AP

更新日期：2011-10-01 00:00:00

abstract：:Use of pure porcine insulin versus partially purified insulin of bovine/porcine origin might be expected to have certain clinical benefits, e.g., a lower incidence of skin reactions, a lower insulin dosage, better diabetes regulation, and greater preservation of endogenous insulin secretion. To test this hypothesis, w...

journal_title：Diabetes care

authors： Asplin C,Raghu P,Clemons P,Lyen K,Tatpati O,McKnight B,Baker L,Guthrie R,Sperling M,Palmer J

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between the use of ACE inhibitors and hospital admission for severe hypoglycemia and to explore the effects of potential confounding variables on this relationship. RESEARCH DESIGN AND METHODS:The association between the use of ACE inhibitors and the incidence of hypoglycemia is c...

journal_title：Diabetes care

authors： Morris AD,Boyle DI,McMahon AD,Pearce H,Evans JM,Newton RW,Jung RT,MacDonald TM

更新日期：1997-09-01 00:00:00

abstract：:A higher prevalence of stroke is found in the patient with both diagnosed and undiagnosed diabetes and glucose intolerance. Because of local cerebral acidosis caused by ischemia and hyperglycemia, morbidity and mortality from a stroke are increased. Most studies show that individuals with admission serum glucose > 120...

journal_title：Diabetes care

authors： Bell DS

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:Pediatric type 2 diabetes prevalence is increasing, with β-cell dysfunction key in its pathogenesis. The RISE Pediatric Medication Study compared two approaches-glargine followed by metformin and metformin alone-in preserving or improving β-cell function in youth with impaired glucose tolerance (IGT) or recen...

journal_title：Diabetes care

authors： RISE Consortium.

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To investigate whether microalbuminuria is associated with markers of the acute-phase response in NIDDM and whether there are ethnic differences in this association among the three main racial groups in Malaysia. RESEARCH DESIGN AND METHODS:NIDDM patients of Chinese, Indian, and Malay origin attending a diab...

journal_title：Diabetes care

authors： Islam N,Kazmi F,Chusney GD,Mattock MB,Zaini A,Pickup JC

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:Observational studies have associated metformin use with a decreased risk of lung cancer incidence in patients with type 2 diabetes, but the studies had important methodological shortcomings. The objective of this study was to determine whether metformin use is associated with a decreased risk of lung cancer ...

journal_title：Diabetes care

authors： Smiechowski BB,Azoulay L,Yin H,Pollak MN,Suissa S

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To compare platelet plasminogen activator inhibitor 1 (PAI-1) release in type II diabetic patients and healthy control subjects. RESEARCH DESIGN AND METHODS:We studied a group of 27 diabetic patients and a group of 16 nondiabetic control subjects. Whole-blood platelet aggregation, defined as a decrease in pl...

journal_title：Diabetes care

authors： Jokl R,Klein RL,Lopes-Virella MF,Colwell JA

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:To study the influence of position changes on 24-h ambulatory blood pressure (ABP) in normotensive or mildly hypertensive normoalbuminuric patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:A cross-sectional evaluation of patients was staged according to the duration of diabetes (DD) and the presence...

journal_title：Diabetes care

authors： Benhamou PY,Mouret S,Quesada JL,Boizel R,Baguet JP,Halimi S,Mallion JM

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of glimepiride versus metformin in pediatric subjects with type 2 diabetes inadequately controlled with diet and exercise alone or oral monotherapy. RESEARCH DESIGN AND METHODS:This 26-week, single-blind, active-controlled, multinational study randomized 285 subjects to rec...

journal_title：Diabetes care

authors： Gottschalk M,Danne T,Vlajnic A,Cara JF

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:Youth with type 1 diabetes face long-term risks of health complications of the disease. Little is known about patients' and parents' knowledge, acquisition of information, and family communication regarding these complications. This paper reports qualitative analyses of parental focus-group discussions of thi...

journal_title：Diabetes care

authors： Buckloh LM,Lochrie AS,Antal H,Milkes A,Canas JA,Hutchinson S,Wysocki T

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To compare diabetes care and outcomes among Haitians, African Americans, and non-Hispanic whites. RESEARCH DESIGN AND METHODS:We analyzed data from 715 Haitian, 1,472 African American, and 466 non-Hispanic white adults with diabetes using χ² testing and multiple logistic regression. RESULTS:Haitians had a h...

journal_title：Diabetes care

authors： Vimalananda VG,Rosenzweig JL,Cabral HJ,David MM,Lasser KE

更新日期：2011-01-01 00:00:00

abstract：:A film test for the rapid detection of plasma/serum 3-hydroxybutyrate (3-OHB) has been developed. The film contains NAD, nitro blue tetrazolium, 3-OHB dehydrogenase, and diaphorase, and the surface is coated with modified biomembrane and can detect 50-1500 microM 3-OHB within 2-3 min. One drop or 50 microliters of pla...

journal_title：Diabetes care

authors： Harano Y,Aoki T,Nakajima Y,Kojima H,Kosugi K,Harano A,Hidaka H,Yamada S,Uno S,Shigeta Y

更新日期：1990-05-01 00:00:00

abstract：OBJECTIVE:To describe market trends for antidiabetic drugs, focusing on newly approved drugs, concomitant use of antidiabetic drugs, and effects of safety concerns and access restrictions on thiazolidinedione use. RESEARCH DESIGN AND METHODS:Nationally projected data on antidiabetic prescriptions for adults dispensed ...

journal_title：Diabetes care

authors： Hampp C,Borders-Hemphill V,Moeny DG,Wysowski DK

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Our objective was to analyze the prevalence, incidence, and mortality of diabetes in a population of 280,539 inhabitants. RESEARCH DESIGN AND METHODS:The incidence, prevalence, and deaths from diabetes at all ages of a population have been prospectively followed in the county of Skaraborg, Sweden, since 1991...

journal_title：Diabetes care

authors： Berger B,Stenström G,Sundkvist G

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:Many of the metabolic benefits of Roux-en-Y gastric bypass (RYGB) occur before weight loss. In this study we investigated the influence of caloric restriction on the improvements in the metabolic responses that occur within the 1st week after RYGB. RESEARCH METHODS AND DESIGN: A mixed meal was administered to...

journal_title：Diabetes care

authors： Isbell JM,Tamboli RA,Hansen EN,Saliba J,Dunn JP,Phillips SE,Marks-Shulman PA,Abumrad NN

更新日期：2010-07-01 00:00:00

abstract：:Exocrine pancreatic insufficiency is frequently associated with diabetes, with high prevalence in both insulin-dependent or insulin-independent patients. Exocrine pancreatic failure has often been perceived as a complication of diabetes. In contrast, recent clinical observations lead to the notion that nonendocrine pa...

journal_title：Diabetes care

authors： Hardt PD,Brendel MD,Kloer HU,Bretzel RG

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:To investigate whether intraperitoneal insulin (IPII) decreases the levels of circulating chylomicron remnants in patients with insulin-dependent diabetes mellitus (IDDM). RESEARCH DESIGN AND METHODS:Eight nonobese, normolipidemic IDDM patients were studied twice: before (while on subcutaneous insulin) and 6...

journal_title：Diabetes care

authors： Georgopoulos A,Saudek CD

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:Diet is the cornerstone treatment of patients with gestational diabetes mellitus (GDM), but its role in maternal and newborn outcomes has been scarcely studied. The purpose of this study was to analyze the efficacy of dietary interventions on maternal or newborn outcomes in patients with GDM. RESEARCH DESIGN...

journal_title：Diabetes care

authors： Viana LV,Gross JL,Azevedo MJ

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:We previously demonstrated a direct correlation between serum insulin levels and gonadal androgens (testosterone and androstenedione) in a group of obese hyperandrogenic predominantly black women. Subsequent work by others in predominantly white women showed conflicting results. To examine these potentially i...

journal_title：Diabetes care

authors： Kitabchi AE,Imseis RE,Bush AJ,Williams-Cleaves B,Pourmotabbed G

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:Alterations of pancreatic β-cell cholesterol content may contribute to β-cell dysfunction. Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Whether genetic variation in ABCA1 and ABCG1 predicts risk of type 2 diabetes i...

journal_title：Diabetes care

authors： Schou J,Tybjærg-Hansen A,Møller HJ,Nordestgaard BG,Frikke-Schmidt R

更新日期：2012-12-01 00:00:00

abstract：:OBJECTIVE Mortality rates have declined substantially over the past decades in the general population, but the situation among diabetic subjects is less clear. The aim of this study was to analyze mortality trends in diabetic and nondiabetic subjects during 1972-2004. RESEARCH DESIGN AND METHODS Since 1972, all patien...

journal_title：Diabetes care

authors： Jansson SP,Andersson DK,Svärdsudd K

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:We sought to determine whether an oral disposition index (DI(O)) predicts the development of diabetes over a 10-year period. First, we assessed the validity of the DI(O) by demonstrating that a hyperbolic relationship exists between oral indexes of insulin sensitivity and beta-cell function. RESEARCH DESIGN ...

journal_title：Diabetes care

authors： Utzschneider KM,Prigeon RL,Faulenbach MV,Tong J,Carr DB,Boyko EJ,Leonetti DL,McNeely MJ,Fujimoto WY,Kahn SE

更新日期：2009-02-01 00:00:00

abstract：:Nocturnal hypoglycemia in insulin-treated diabetic persons is often difficult to recognize clinically. It has been suggested that a useful biochemical test to demonstrate this would be the increased excretion of cortisol in the urine during the overnight period. However, of six diabetic persons who had nocturnal hypog...

journal_title：Diabetes care

authors： Scott RS,Scandrett MS

更新日期：1981-09-01 00:00:00

abstract：:Chemical test strips for estimating blood glucose have been shown to be reliable, rapid, and convenient when properly used. This study compares a new product, the Ames Visidex (Miles Laboratories, Elkhart, Indiana), and an established product, the Bio-Dynamics Chemstrip bG (Boehringer-Mannheim, Indianapolis, Indiana) ...

journal_title：Diabetes care

authors： Frindik JP,Kassner DA,Pirkle DA,Kemp SF,Hoff C

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVE:Transforming growth factor (TGF)-beta1 is overexpressed in diabetes as a consequence of hyperglycemia and the creation of early glycated end products and may be responsible for the characteristic structural renal changes associated with diabetes. We sought to examine the role of both urinary and circulating T...

journal_title：Diabetes care

authors： Chaturvedi N,Schalkwijk CG,Abrahamian H,Fuller JH,Stehouwer CD,EURODIAB Prospective Complications Study Group.

更新日期：2002-12-01 00:00:00

abstract：:Skin wrinkling, which may be dependent on peripheral autonomic innervation, was assessed in 100 normal and 42 diabetic subjects using a temperature-controlled water bath with immersion of the hands for 30 min. Markedly decreased skin wrinkling was observed in diabetic subjects and in manual workers, but did not correl...

journal_title：Diabetes care

authors： Clark CV,Pentland B,Ewing DJ,Clarke BF

更新日期：1984-05-01 00:00:00

abstract：OBJECTIVE:The relative roles of insulin resistance and beta-cell dysfunction in the pathogenesis of impaired glucose tolerance (IGT) and type 2 diabetes are debated. First-degree relatives of individuals with type 2 diabetes are at increased risk of developing hyperglycemia. RESEARCH DESIGN AND METHODS:We evaluated th...

journal_title：Diabetes care

authors： Cnop M,Vidal J,Hull RL,Utzschneider KM,Carr DB,Schraw T,Scherer PE,Boyko EJ,Fujimoto WY,Kahn SE

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To assess the effects of empagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, on broad biological systems through proteomics. RESEARCH DESIGN AND METHODS:Aptamer-based proteomics was used to quantify 3,713 proteins in 144 paired plasma samples obtained from 72 participants across the ...

journal_title：Diabetes care

authors： Ferrannini E,Murthy AC,Lee YH,Muscelli E,Weiss S,Ostroff RM,Sattar N,Williams SA,Ganz P

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To examine if dual replacement with insulin and rhIGF-I, recombinant human insulin-like growth factor I (rhIGF-I) may be safe and result in improved metabolic control and reduced insulin usage. RESEARCH DESIGN AND METHODS:Forty-three patients with IDDM were randomized to receive a daily injection of rhIGF-I ...

journal_title：Diabetes care

authors： Quattrin T,Thrailkill K,Baker L,Litton J,Dwigun K,Rearson M,Poppenheimer M,Giltinan D,Gesundheit N,Martha P Jr

更新日期：1997-03-01 00:00:00