Abstract:
:Given the importance of glycemic control in the development of diabetes complications, the plethora of tools now available to monitor the day-to-day trends in glycemia is remarkable. In this regard, self-monitoring of blood glucose (SMBG) has been considered a key component of patient management. Arguably, there remains almost universal agreement that SMBG should be available to all diabetic patients regardless of current treatment strategy. However, recently there have been reports that have challenged the current paradigm that all patients should use SMBG and concluded that SMBG for type 2 diabetic patients not on insulin may not be beneficial on glycemic control and must be weighed against the expense and inconvenience. In the counterpoint narrative following the contribution by Malanda et al., Drs. Polonsky and Fisher provide a compelling argument suggesting that while it is evident that implementing SMBG in unstructured ways without training patients and clinicians is likely to be a waste of resources, there are effective and powerful ways to use structured SMBG in insulin-naïve type 2 diabetic patients. -William T. Cefalu, MD Editor in Chief, Diabetes Care.
journal_name
Diabetes Carejournal_title
Diabetes careauthors
Polonsky WH,Fisher Ldoi
10.2337/dc12-0731subject
Has Abstractpub_date
2013-01-01 00:00:00pages
179-82issue
1eissn
0149-5992issn
1935-5548pii
36/1/179journal_volume
36pub_type
评论,杂志文章相关文献
DIABETES CARE文献大全abstract:OBJECTIVE:Obesity is a well-known risk factor for vitamin D deficiency. We evaluated the interrelationship between vitamin D status, body size, and glucose homeostasis, measured by HbA1c (A1C). RESEARCH DESIGN AND METHODS:Data are from the survey of the 45-year-old 1958 British birth cohort (2002-2004). Information on...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc06-0946
更新日期:2006-10-01 00:00:00
abstract::We measured plasma lipid and lipoprotein levels at baseline and at 6-mo intervals in 47 normolipidemic patients with classic insulin-dependent diabetes mellitus treated either with a conventional (n = 21) or intensive (n = 26) diabetes-treatment program. Patients were followed for a mean of 3 yr (range 1-4 yr). Intens...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.10.6.729
更新日期:1987-11-01 00:00:00
abstract:OBJECTIVE:To evaluate glycemia and metrics of glucose variability in youth with type 1 diabetes, and to assess patterns of 24-h glucose variability according to pubertal status. RESEARCH DESIGN AND METHODS:Metrics of glycemia, glucose variability, and glucose patterns were assessed by using 4 weeks of continuous gluco...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc19-0083
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To evaluate effects of vildagliptin and metformin on blood pressure (BP) and heart rate (HR) responses to intraduodenal (ID) glucose in diet-controlled type 2 diabetes. RESEARCH DESIGN AND METHODS:Study A compared vildagliptin (50 mg) and placebo, given 60 min before a 120-min ID glucose infusion at 2 or 4 k...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc16-2391
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:To describe market trends for antidiabetic drugs, focusing on newly approved drugs, concomitant use of antidiabetic drugs, and effects of safety concerns and access restrictions on thiazolidinedione use. RESEARCH DESIGN AND METHODS:Nationally projected data on antidiabetic prescriptions for adults dispensed ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc13-2289
更新日期:2014-01-01 00:00:00
abstract::In seven type II (non-insulin-dependent) diabetic patients, given either 50 g glucose or a mixed meal potentially containing 61 g glucose as starch and sucrose, the postmeal plasma glucose area integrated over 4 h was less after the mixed meal. The insulin area was considerably greater (2.1-fold). The greater increase...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.11.1.72
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:To assess performance of nonfasting tests to screen children for dysglycemia (prediabetes or diabetes). RESEARCH DESIGN AND METHODS:This was a cross-sectional study of 254 overweight or obese (BMI ≥85th percentile) children aged 10-17 years. Subjects came for two visits to a clinical research unit. For visit...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc11-0827
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:This study evaluated the ability of the Building, Relating, Assessing, and Validating Outcomes (BRAVO) risk engine to accurately project cardiovascular outcomes in three major clinical trials-BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME), C...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc20-0227
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To investigate the association between neck circumference and central obesity, overweight, and metabolic syndrome in Chinese individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 3,182 diabetic subjects (aged 20-80 years) were recruited from 15 community health centers in Beijing using a m...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc10-0798
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:Troglitazone was recently reported to specifically promote the differentiation of pre-adipocytes into adipocytes in vitro in subcutaneous fat only, indicating a relation to insulin-resistance-improving action of troglitazone. To expand on this finding, we investigated at the clinical level how long-term admin...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.22.6.908
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes and inadequate glycemic control on diet and exercise. RESEARCH DESIGN AND METHODS:In a 24-week, randomized, double-blind, placebo-controlled, parallel-group study, 1,091 patients w...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc07-0627
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:To explore the relationship between the genetic polymorphisms of PPARgamma (Pro12Ala, C1431T, and C-2821T) and the risk of ischemic stroke and to investigate whether these genetic polymorphisms of PPARgamma would modify the risk of ischemic stroke among patients with hypertension or diabetes. RESEARCH DESIGN...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc09-0717
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:Few multiple lifestyle behavior change programs have been designed to reduce the risk of coronary heart disease in postmenopausal women with type 2 diabetes. This study tested the effectiveness of the Mediterranean Lifestyle Program (MLP), a comprehensive lifestyle self-management program (Mediterranean low-s...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.26.8.2288
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:Nonalcoholic fatty liver disease is highly prevalent in obese and type 2 diabetic individuals and is strongly associated with dyslipidemia and inflammation. Weight loss and/or pharmacotherapy are commonly used to correct these abnormalities. RESEARCH DESIGN AND METHODS:We performed a 16-week intervention tri...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc09-1765
更新日期:2010-05-01 00:00:00
abstract::Epidemiological studies performed over the past 40 years have shown that the prevalence of diagnosed diabetes has increased dramatically in the U.S. and that a substantial proportion of the population has undiagnosed diabetes, impaired fasting glucose, and impaired glucose tolerance. Diabetes is most prevalent in mino...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.21.3.c11
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVE:People with diabetes have an increased risk of coronary artery disease (CAD). An unanswered question is what portion of CAD can be attributed to insulin resistance, related metabolic variables, and other known CAD risk factors. RESEARCH DESIGN AND METHODS:The Archimedes model was used to estimate the proport...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc08-0854
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence and clinical associations of impaired awareness of hypoglycemia in a population-based sample of children and adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS:A validated questionnaire was administered to 656 patients with type 1 diabetes over a 6-month period to deter...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc09-0541
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To describe the clinical experience and the pharmacokinetics of U-500 regular insulin in severely insulin-resistant obese type 2 diabetic patients. RESEARCH DESIGN AND METHODS:Patients requiring >200 units of insulin with A1C levels >8.0% were switched to U-500 regular insulin. For the pharmacokinetic study,...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc09-1490
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To provide reliable data on the incidence of insulin-dependent diabetes mellitus (IDDM) in children (< 15 years of age) in Avellaneda, Argentina. RESEARCH DESIGN AND METHODS:A registry was established in Avellaneda, Argentina. The first registry was started in 1989, retrospective data collection was updated ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.17.9.1022
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to examine medication adherence and other self-management practices as potential determinants of higher glycemic risk among black relative to white patients. RESEARCH DESIGN AND METHODS:We used a retrospective, longitudinal repeated-measures design to model the contribution of m...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究
doi:10.2337/dc07-1924
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:We sought to determine whether an oral disposition index (DI(O)) predicts the development of diabetes over a 10-year period. First, we assessed the validity of the DI(O) by demonstrating that a hyperbolic relationship exists between oral indexes of insulin sensitivity and beta-cell function. RESEARCH DESIGN ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc08-1478
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:Poorer glycemic control in type 1 diabetes may alter N-glycosylation patterns on circulating glycoproteins, and these alterations may be linked with diabetic kidney disease (DKD). We investigated associations between N-glycans and glycemic control and renal function in type 1 diabetes. RESEARCH DESIGN AND ME...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc17-1042
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To evaluate whether homeostasis model assessment-estimated insulin resistance (HOMA-IR) is an independent predictor of cardiovascular disease (CVD) in type 2 diabetes. RESEARCH DESIGN AND METHODS:Conventional CVD risk factors (sex, age, smoking, plasma lipids, blood pressure, and metabolic control) and insul...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究
doi:10.2337/diacare.25.7.1135
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:Dietary fiber has recently received recognition for reducing the risk of developing diabetes and heart disease. The implication is that it may have therapeutic benefit in prediabetic metabolic conditions. To test this hypothesis, we investigated the effect of supplementing a high-carbohydrate diet with fiber ...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.2337/diacare.23.1.9
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of trans fatty acids (TFAs) on type 2 diabetes mellitus (DM) by specific TFA subtype or method of assessment. RESEARCH DESIGN AND METHODS:In the Cardiovascular Health Study, plasma phospholipid trans (t)-16:1n9, t-18:1, and cis (c)/t-, t/c-, and t/t-18:2 were measured in blood draw...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2337/dc14-2101
更新日期:2015-06-01 00:00:00
abstract::To assess the possible value of the use of high-purity pork insulin (HPPI) in the United States, the serum insulin (I), pancreatic polypeptide (PP), glucagon (G), and somatostatin (SRIF) antibody binding characteristics have been determined in 90 conventional insulin-treated diabetic subjects and related to their degr...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.4.3.337
更新日期:1981-05-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of diabetes and impaired glucose tolerance (IGT) in the adult population of Rio de Janeiro, a two-stage cross-sectional survey was carried out in a random sample of 2,051 individuals aged 30-69 years from Rio de Janeiro city in Brazil. RESEARCH DESIGN AND METHODS:Subjects were first ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.19.6.663
更新日期:1996-06-01 00:00:00
abstract::Metformin is and has been considered as first-line therapy for type 2 diabetes for over a quarter of a century. Like other biguanides, metformin can cause a lactic acidosis that is exceptionally rare but fatal. The likelihood of metformin-associated lactic acidosis is substantially higher in patients with kidney impai...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc15-2534
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:Hyperinsulinemic euglycemia, or insulin resistance syndrome (IRS), is associated with increased morbidity and mortality. Although thought to be associated with proinflammatory states, little work has been done in this area. Here, we determined the impact of IRS on functional, biochemical, metabolic, and infla...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc07-0649
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:It is still controversial whether sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) are equally effective in patients with diabetes. In these patients, multiple individual variables may be responsible for neointimal hyperplasia, thus making difficult the comparison of the two drug-eluting stent...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2337/dc07-1377
更新日期:2008-01-01 00:00:00