Diabetes in America: epidemiology and scope of the problem.

abstract：OBJECTIVE:To investigate whether intraperitoneal insulin (IPII) decreases the levels of circulating chylomicron remnants in patients with insulin-dependent diabetes mellitus (IDDM). RESEARCH DESIGN AND METHODS:Eight nonobese, normolipidemic IDDM patients were studied twice: before (while on subcutaneous insulin) and 6...

journal_title：Diabetes care

authors： Georgopoulos A,Saudek CD

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:Limited information is available about glycemic outcomes with a closed-loop control (CLC) system compared with a predictive low-glucose suspend (PLGS) system. RESEARCH DESIGN AND METHODS:After 6 months of use of a CLC system in a randomized trial, 109 participants with type 1 diabetes (age range, 14-72 years...

journal_title：Diabetes care

authors： Brown SA,Beck RW,Raghinaru D,Buckingham BA,Laffel LM,Wadwa RP,Kudva YC,Levy CJ,Pinsker JE,Dassau E,Doyle FJ 3rd,Ambler-Osborn L,Anderson SM,Church MM,Ekhlaspour L,Forlenza GP,Levister C,Simha V,Breton MD,Kollman C,

更新日期：2020-08-01 00:00:00

abstract：:OBJECTIVE--To assess the relationship between family history and different types of obesity and change in obesity in a longitudinal population study. RESEARCH DESIGN AND METHODS--A longitudinal population study of 1462 randomly selected women (38-60 yr old) was conducted in Göteborg, Sweden, in 1968-69. The women were...

journal_title：Diabetes care

authors： Lapidus L,Bengtsson C,Lissner L,Smith U

更新日期：1992-11-01 00:00:00

abstract：:Japanese migrants and their offspring on the island of Hawaii and Japanese living in Hiroshima were examined for diabetes mellitus and its vascular complications. the same methods and investigators were used in both locations. Death certificates of Japanese and Caucasians dying on the island during the past 26 yr were...

journal_title：Diabetes care

authors： Kawate R,Yamakido M,Nishimoto Y,Bennett PH,Hamman RF,Knowler WC

更新日期：1979-03-01 00:00:00

abstract：OBJECTIVE:Given the role of gut microbiota in regulating metabolism, probiotics administered during pregnancy might prevent gestational diabetes mellitus (GDM). This question has not previously been studied in high-risk overweight and obese pregnant women. We aimed to determine whether probiotics (Lactobacillus rhamnos...

journal_title：Diabetes care

authors： Callaway LK,McIntyre HD,Barrett HL,Foxcroft K,Tremellen A,Lingwood BE,Tobin JM,Wilkinson S,Kothari A,Morrison M,O'Rourke P,Pelecanos A,Dekker Nitert M

更新日期：2019-03-01 00:00:00

abstract：:The clinical diagnosis of new-onset type 1 diabetes has, for many years, been considered relatively straightforward. Recently, however, there is increasing awareness that within this single clinical phenotype exists considerable heterogeneity: disease onset spans the complete age range; genetic susceptibility is compl...

journal_title：Diabetes care

authors： Battaglia M,Ahmed S,Anderson MS,Atkinson MA,Becker D,Bingley PJ,Bosi E,Brusko TM,DiMeglio LA,Evans-Molina C,Gitelman SE,Greenbaum CJ,Gottlieb PA,Herold KC,Hessner MJ,Knip M,Jacobsen L,Krischer JP,Long SA,Lundgren M

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:In a few previous studies, cardiovascular disease (CVD) risk factors (RFs) have been shown to predict diabetes. Our objective was to determine whether the presence of CVD RFs predict the eventual development of diabetes after controlling for known RFs, such as directly measured insulin resistance and obesity....

journal_title：Diabetes care

authors： D'Agostino RB Jr,Hamman RF,Karter AJ,Mykkanen L,Wagenknecht LE,Haffner SM,Insulin Resistance Atherosclerosis Study Investigators.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To describe the clinical and immunologic characteristics of fulminant type 1 diabetes, a novel subtype of type 1 diabetes, we conducted a nationwide survey. RESEARCH DESIGN AND METHODS:History and laboratory data, including islet-related autoantibodies, were examined in 222 patients with fulminant and nonful...

journal_title：Diabetes care

authors： Imagawa A,Hanafusa T,Uchigata Y,Kanatsuka A,Kawasaki E,Kobayashi T,Shimada A,Shimizu I,Toyoda T,Maruyama T,Makino H

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:To analyze the relationship between maternal adiponectin (mAdiponectin) and cord blood adiponectin (cbAdiponectin) multimeric forms (high molecular weight [HMW], medium molecular weight [MMW], and low molecular weight [LMW]) in a cohort of gestational diabetes mellitus (GDM) and normal glucose-tolerant (NGT) ...

journal_title：Diabetes care

authors： Ballesteros M,Simón I,Vendrell J,Ceperuelo-Mallafré V,Miralles RM,Albaiges G,Tinahones F,Megia A

更新日期：2011-11-01 00:00:00

abstract：:This study compares the utility of nonenzymatically glycosylated serum proteins (lys-GSP) to glycosylated hemoglobins (HbA1a-c) as control indices of glucose homeostasis in patients with IDDM. The diagnostic value of lys-GSP was also examined in patients with non-insulin-dependent diabetes mellitus, in subjects with i...

journal_title：Diabetes care

authors： Schleicher ED,Gerbitz KD,Dolhofer R,Reindl E,Wieland OH,Edelmann E,Haslbeck M,Kemmler W,Walter H,Mehnert H

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:To quantify the impact of diabetes status on healthy and disabled years of life for older adults in the U.S. and provide a baseline from which to evaluate ongoing national public health efforts to prevent and control diabetes and disability. RESEARCH DESIGN AND METHODS:Adults (n = 20,008) aged 50 years and o...

journal_title：Diabetes care

authors： Bardenheier BH,Lin J,Zhuo X,Ali MK,Thompson TJ,Cheng YJ,Gregg EW

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:People with type 2 diabetes have impaired exercise responses even in the absence of cardiovascular complications. One key factor associated with the exercise intolerance is abnormally slowed oxygen uptake (VO2) kinetics during submaximal exercise. The mechanisms of this delayed adaptation during exercise are ...

journal_title：Diabetes care

authors： Bauer TA,Reusch JE,Levi M,Regensteiner JG

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:Type 2 diabetes is a heterogeneous disease in which both beta-cell dysfunction and insulin resistance are pathogenetic factors. Disproportionate hyperproinsulinemia (elevated proinsulin/insulin) is another abnormality in type 2 diabetes whose mechanism is unknown. Increased demand due to obesity and/or insuli...

journal_title：Diabetes care

authors： Røder ME,Dinesen B,Hartling SG,Houssa P,Vestergaard H,Sodoyez-Goffaux F,Binder C

更新日期：1999-04-01 00:00:00

abstract：:It would be advantageous to be able to measure glycosylated hemoglobin (GHb) from a sample of blood dried on paper and sent to the physician by the patient. Indeed, such a technique has been introduced by Isolab (Akron, OH). We tested the validity of the method to determine whether applying the blood to paper and imme...

journal_title：Diabetes care

authors： Broussolle C,Saudek CD

更新日期：1987-05-01 00:00:00

abstract：:To evaluate the importance of dialysis in the determination of glycosylated hemoglobin (HbA1), we studied blood glucose and HbA1 in 38 insulin-dependent diabetic children during a morning fast and again 6 h postprandially. We used two methods to determine glycosylated hemoglobin: (1) the conventional macrocolumn metho...

journal_title：Diabetes care

authors： Ditzel J,Kjaergaard JJ,Kawahara R,Ostergaard GZ,Mourits-Andersen T

更新日期：1981-09-01 00:00:00

abstract：OBJECTIVE:Blood pressure ranges associated with cardiovascular disease (CVD) events in advanced type 2 diabetes are not clear. Our objective was to determine whether baseline and follow-up (On-Study) systolic blood pressure (SBP), diastolic blood pressure (DBP), and SBP combined with DBP predict CVD events in the Veter...

journal_title：Diabetes care

authors： Anderson RJ,Bahn GD,Moritz TE,Kaufman D,Abraira C,Duckworth W,VADT Study Group.

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Dietary protein is an important modulator of glucose metabolism. However, studies regarding the association between dietary protein intake and gestational diabetes mellitus (GDM) risk are sparse. This study was to examine the association. RESEARCH DESIGN AND METHODS:Our study included 21,457 singleton pregna...

journal_title：Diabetes care

authors： Bao W,Bowers K,Tobias DK,Hu FB,Zhang C

更新日期：2013-07-01 00:00:00

abstract：:Urinary albumin excretion rate (radial immunodiffusion), glomerular filtration rate (GFR) (single-shot 51Cr-EDTA technique), and arterial blood pressure (BP) were measured in 12 juvenile-onset, insulin-dependent diabetic patients with persistent proteinuria (greater than 0.5 g/day) due to diabetic nephropathy. Mean ag...

journal_title：Diabetes care

authors： Parving HH,Andersen AR,Smidt UM,Friisberg B,Svendsen PA

更新日期：1981-07-01 00:00:00

abstract：:Because recent knowledge indicates that the distribution of fat deposits in men may be a better predictor of cardiovascular disease than the degree of obesity alone, some risk factors for atherosclerosis were evaluated in 51 middle-aged men with non-insulin-dependent diabetes mellitus. Abdominal adiposity (waist/hip r...

journal_title：Diabetes care

authors： Van Gaal L,Rillaerts E,Creten W,De Leeuw I

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate factors associated with depression in type 1 and type 2 diabetes and test whether these differ from factors associated with depression in the nondiabetic population. RESEARCH DESIGN AND METHODS:In an unselected population study comprising 60,869 individuals, poten...

journal_title：Diabetes care

authors： Engum A,Mykletun A,Midthjell K,Holen A,Dahl AA

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:We investigated the effect of glimepiride, a third-generation sulfonylurea hypoglycemic agent, on insulin resistance in elderly patients with type 2 diabetes, in connection with plasma adiponectin and 8-epi-prostagrandin F2alpha (8-epi-PGF2alpha), an oxidative stress marker. RESEARCH DESIGN AND METHODS:A tot...

journal_title：Diabetes care

authors： Tsunekawa T,Hayashi T,Suzuki Y,Matsui-Hirai H,Kano H,Fukatsu A,Nomura N,Miyazaki A,Iguchi A

更新日期：2003-02-01 00:00:00

abstract：:Many of the family psychosocial variables significantly related to child abuse are also significantly related to insulin-dependent diabetes mellitus (IDDM) control. These variables are reviewed, and an increased child abuse risk factor for children with IDDM is discussed. Behavioral indicators of families experiencing...

journal_title：Diabetes care

authors： Horan PF,Gwynn C,Renzi D

更新日期：1986-05-01 00:00:00

abstract：OBJECTIVE:Diabetes has been associated with chronic neurodegeneration. We performed a systematic review and meta-analysis to assess the relationship between pre-existing diabetes and Parkinson's disease (PD). RESEARCH DESIGN AND METHODS:Original articles in English published up to 10 May 2011 were searched for in elec...

journal_title：Diabetes care

authors： Cereda E,Barichella M,Pedrolli C,Klersy C,Cassani E,Caccialanza R,Pezzoli G

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:This national, population-based study reports diabetes incidence based on oral glucose tolerance tests (OGTTs) and identifies risk factors for diabetes in Australians. RESEARCH DESIGN AND METHODS:The Australian Diabetes, Obesity and Lifestyle Study followed-up 5,842 participants over 5 years. Normal glycemia...

journal_title：Diabetes care

authors： Magliano DJ,Barr EL,Zimmet PZ,Cameron AJ,Dunstan DW,Colagiuri S,Jolley D,Owen N,Phillips P,Tapp RJ,Welborn TA,Shaw JE

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:To compare fenofibric acid (FA) + statin to respective monotherapies on the prevalence of metabolic syndrome and its diagnostic components in patients with mixed dyslipidemia. RESEARCH DESIGN AND METHODS:Post hoc analysis of over 2,000 metabolic syndrome patients administered either FA + low- or moderate-dos...

journal_title：Diabetes care

authors： Bays HE,Roth EM,McKenney JM,Kelly MT,Thakker KM,Setze CM,Obermeyer K,Sleep DJ

更新日期：2010-09-01 00:00:00

abstract：:The concept of gestational diabetes goes back at least to 1946. Over the years, sophistication has increased regarding the pathophysiology of this condition. However, there is not universal agreement on how to diagnose gestational diabetes. The most widely used diagnostic criteria in the U.S. were validated by their p...

journal_title：Diabetes care

authors： Coustan DR,Carpenter MW

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:Malabsorptive bariatric surgery (biliopancreatic diversion and biliointestinal bypass [BIBP]) reduces serum cholesterol levels more than restrictive surgery (adjustable gastric banding [AGB]), and this is thought to be due to greater weight loss. Our aim was to evaluate the changes of cholesterol metabolism i...

journal_title：Diabetes care

authors： Benetti A,Del Puppo M,Crosignani A,Veronelli A,Masci E,Frigè F,Micheletto G,Panizzo V,Pontiroli AE

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Several meta-analyses of observational studies suggested that metformin use reduces cancer risk in type 2 diabetes. However, this result was not confirmed by the few available randomized controlled trials (RCTs), and many observational studies on metformin and cancer were potentially afflicted with time-relat...

journal_title：Diabetes care

authors： Kowall B,Rathmann W,Kostev K

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of topical human recombinant basic fibroblast growth factor (bFGF) on the healing of diabetic neurotrophic foot ulcers. RESEARCH DESIGN AND METHODS:Seventeen diabetic patients suffering from chronic neuropathic ulcer of the plantar surface of the foot entered a pilot, random...

journal_title：Diabetes care

authors： Richard JL,Parer-Richard C,Daures JP,Clouet S,Vannereau D,Bringer J,Rodier M,Jacob C,Comte-Bardonnet M

更新日期：1995-01-01 00:00:00

abstract：:In this study, 18 type I (insulin-dependent) diabetic subjects aged 22-35 yr (mean age 29.3) and within 10 yr of diagnosis (mean 7.7) performed a battery of cognitive and psychomotor tasks under conditions of hypoglycemia (50 mg/dl), normoglycemia (100 mg/dl), and hyperglycemia (300 mg/dl). Blood glucose levels during...

journal_title：Diabetes care

authors： Hoffman RG,Speelman DJ,Hinnen DA,Conley KL,Guthrie RA,Knapp RK

更新日期：1989-03-01 00:00:00