Intraperitoneal insulin delivery decreases the levels of chylomicron remnants in patients with IDDM.

abstract：OBJECTIVE:Women with breast cancer and diabetes face worse outcomes than those with breast cancer without diabetes; however, the contribution of comorbidity to these disparities remains unclear. We evaluated the impact of diabetes on receipt of cancer treatments as well as mortality while accounting for other comorbidi...

journal_title：Diabetes care

authors： Lega IC,Austin PC,Fischer HD,Fung K,Krzyzanowska MK,Amir E,Lipscombe LL

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:The pharmacokinetics and glucodynamics of a new insulin analog, insulin lispro, and regular human insulin were compared and contrasted after subcutaneous administrations in femoral, deltoid, and abdominal injection sites. RESEARCH DESIGN AND METHODS:Single 0.2 U/kg doses of insulin lispro and regular insulin...

journal_title：Diabetes care

authors： ter Braak EW,Woodworth JR,Bianchi R,Cerimele B,Erkelens DW,Thijssen JH,Kurtz D

更新日期：1996-12-01 00:00:00

abstract：:Fifty-one insulin-dependent diabetic patients, 26 children and 25 adults, participated in an open uncontrolled study of the safety and efficacy of human insulin (Novo). The patients, who had previously been treated exclusively with porcine insulin, were followed in two outpatient clinics during a 3-mo study period. Du...

journal_title：Diabetes care

authors： Lyngsøe J,Vestermark S

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:To project the number of people with diagnosed diabetes in the U.S. through 2050, accounting for changing demography and diabetes prevalence rates. RESEARCH DESIGN AND METHODS:We combined age-, sex-, and race-specific diagnosed diabetes prevalence rates-predicted from 1980-1998 trends in prevalence data from...

journal_title：Diabetes care

authors： Boyle JP,Honeycutt AA,Narayan KM,Hoerger TJ,Geiss LS,Chen H,Thompson TJ

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:To study the association between microalbuminuria and development of preeclampsia and preterm delivery in pregnant women with type 1 diabetes. RESEARCH DESIGN AND METHODS:This was a population-based prospective study in 846 normoalbuminuric or microalbuminuric women with type 1 diabetes without antihypertens...

journal_title：Diabetes care

authors： Jensen DM,Damm P,Ovesen P,Mølsted-Pedersen L,Beck-Nielsen H,Westergaard JG,Moeller M,Mathiesen ER

更新日期：2010-01-01 00:00:00

abstract：:OBJECTIVE To determine if glucose and C-peptide values obtained as part of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study could be used to estimate insulin sensitivity during late pregnancy. RESEARCH DESIGN AND METHODS A total of 78 women enrolled in the HAPO study were recruited for this ancillary study...

journal_title：Diabetes care

authors： Radaelli T,Farrell KA,Huston-Presley L,Amini SB,Kirwan JP,McIntyre HD,Catalano PM

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:We examined the joint effects of insomnia and objective short sleep duration, the combination of which is associated with higher morbidity, on diabetes risk. RESEARCH DESIGN AND METHODS:A total of 1,741 men and women randomly selected from Central Pennsylvania were studied in the sleep laboratory. Insomnia w...

journal_title：Diabetes care

authors： Vgontzas AN,Liao D,Pejovic S,Calhoun S,Karataraki M,Bixler EO

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To compare diabetes care and outcomes among Haitians, African Americans, and non-Hispanic whites. RESEARCH DESIGN AND METHODS:We analyzed data from 715 Haitian, 1,472 African American, and 466 non-Hispanic white adults with diabetes using χ² testing and multiple logistic regression. RESULTS:Haitians had a h...

journal_title：Diabetes care

authors： Vimalananda VG,Rosenzweig JL,Cabral HJ,David MM,Lasser KE

更新日期：2011-01-01 00:00:00

abstract：:The role of hyperinsulinemia in the pathogenesis of triglyceride (TG) and VLDL over-production in insulin-resistant states remains controversial. While studies in humans and animals have generally suggested that chronic hyperinsulinemia facilitates VLDL production, particularly in the presence of an abundant supply of...

journal_title：Diabetes care

authors： Lewis GF,Steiner G

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:Some evidence suggests an inverse association between type 2 diabetes and androgens in men and a positive association between type 2 diabetes and androgens in women. The purpose of this community-based study was to evaluate sex differences in the association between endogenous total and bioavailable estrogen ...

journal_title：Diabetes care

authors： Goodman-Gruen D,Barrett-Connor E

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:Available basal insulin formulations do not provide a constant and reliable 24-h insulin supply. We compared the efficacy and safety of glargine (a long-acting insulin analog) and NPH insulins in insulin-naive type 2 diabetic patients treated with oral antidiabetic agents. RESEARCH DESIGN AND METHODS:There w...

journal_title：Diabetes care

authors： Yki-Järvinen H,Dressler A,Ziemen M,HOE 901\/300s Study Group.

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Adopt a multidisciplinary approach to evaluate a virtually supervised home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes. RESEARCH DESIGN AND METHODS:Eleven individuals with type 1 diabetes (seven women; age 30 ± 3 years; [Formula: see text] 2.5 ± 0.2 L/min; du...

journal_title：Diabetes care

authors： Scott SN,Shepherd SO,Andrews RC,Narendran P,Purewal TS,Kinnafick F,Cuthbertson DJ,Atkinson-Goulding S,Noon T,Wagenmakers AJM,Cocks M

更新日期：2019-12-01 00:00:00

abstract：:OBJECTIVE We evaluated relationships of oral glucose tolerance testing (OGTT)-derived measures of insulin sensitivity and pancreatic β-cell function with indices of diabetes complications in a cross-sectional study of patients with type 2 diabetes who are free of overt cardiovascular or renal disease. RESEARCH DESIGN ...

journal_title：Diabetes care

authors： Mulvey CK,McNeill AM,Girman CJ,Churchill TW,Terembula K,Ferguson JF,Shah R,Mehta NN,Qasim AN,Rickels MR,Reilly MP

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To assess the mechanistic effects of the glucagon-like peptide 1 (GLP-1) receptor agonist liraglutide and the dipeptidyl peptidase 4 (DPP-4) inhibitor sitagliptin on (exocrine) pancreatic physiology and morphology. RESEARCH DESIGN AND METHODS:For this randomized, double-blind, parallel-group trial, 55 patien...

journal_title：Diabetes care

authors： Smits MM,Tonneijck L,Muskiet MH,Kramer MH,Pieters-van den Bos IC,Vendrik KE,Hoekstra T,Bruno MJ,Diamant M,van Raalte DH,Cahen DL

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the effect of 24 weeks of treatment with 45 mg/day pioglitazone on peripheral skin blood flow (SkBF) and skin nitric oxide (NO) production in vivo in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:This was a randomized, parallel, cross-over, double-blind...

journal_title：Diabetes care

authors： Vinik AI,Ullal J,Parson HK,Barlow PM,Casellini CM

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To determine the rheological properties of polymorphonuclear leukocytes (PMN) from non-insulin-dependent diabetes mellitus (NIDDM) patients. RESEARCH DESIGN AND METHODS:The deformability of PMN from 33 NIDDM subjects, 13 with impaired glucose tolerance (IGT), and 22 with normal glucose tolerance (NGT) was st...

journal_title：Diabetes care

authors： Pécsvarády Z,Fisher TC,Darwin CH,Fabók A,Maqueda TS,Saad MF,Meiselman HJ

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To test whether diabetic polyneuropathies (DPNs), retinopathy, or nephropathy is more prevalent in subjects with impaired glycemia (IG) (abnormality of impaired fasting glucose [IFG], impaired glucose tolerance [IGT], or impaired HbA(1c) [IA1C]) than in healthy subjects (non-IG). RESEARCH DESIGN AND METHODS:...

journal_title：Diabetes care

authors： Dyck PJ,Clark VM,Overland CJ,Davies JL,Pach JM,Dyck PJ,Klein CJ,Rizza RA,Melton LJ 3rd,Carter RE,Klein R,Litchy WJ

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:The monosaccharides resulting from the digestion of ingested carbohydrates are glucose, fructose, and galactose. Of these three monosaccharides, only ingested glucose resulted in a large increase in the plasma glucose concentration. Fructose (Metabolism 41:510-517, 1992) and galactose (Metabolism 42:1560-1567...

journal_title：Diabetes care

authors： Gannon MC,Nuttall FQ,Westphal SA,Fang S,Ercan-Fang N

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:We investigated the natural history of glucokinase (GCK)-related maturity-onset diabetes of the young type 2 (MODY2), notably the factors associated with deterioration of hyperglycemia over time. RESEARCH DESIGN AND METHODS:We report an 11-year follow-up of glucose tolerance and indexes of insulin secretion ...

journal_title：Diabetes care

authors： Martin D,Bellanné-Chantelot C,Deschamps I,Froguel P,Robert JJ,Velho G

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between subclinical cardiac dysfunction and aerobic exercise capacity (peak VO2) in adults with type 2 diabetes (T2D), a group at high risk of developing heart failure. RESEARCH DESIGN AND METHODS:Cross-sectional study. We prospectively enrolled a multiethnic cohort of asymptomatic...

journal_title：Diabetes care

authors： Gulsin GS,Henson J,Brady EM,Sargeant JA,Wilmot EG,Athithan L,Htike ZZ,Marsh AM,Biglands JD,Kellman P,Khunti K,Webb D,Davies MJ,Yates T,McCann GP

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Pediatric type 2 diabetes prevalence is increasing, with β-cell dysfunction key in its pathogenesis. The RISE Pediatric Medication Study compared two approaches-glargine followed by metformin and metformin alone-in preserving or improving β-cell function in youth with impaired glucose tolerance (IGT) or recen...

journal_title：Diabetes care

authors： RISE Consortium.

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Neonatal diabetes is a heterogeneous group of disorders with diabetes manifestation in the first 6 months of life. The most common etiology in permanent neonatal diabetes is mutations of the ATP-sensitive K(+) channel subunits; in transient neonatal diabetes, chromosome 6q24 abnormalities are the most common ...

journal_title：Diabetes care

authors： Staník J,Lethby M,Flanagan SE,Gasperíková D,Milosovicová B,Lever M,Bullman H,Zubcevic L,Hattersley AT,Ellard S,Ashcroft FM,Klimes I

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Emerging epidemiological evidence suggests that higher magnesium intake may reduce diabetes incidence. We aimed to examine the association between magnesium intake and risk of type 2 diabetes by conducting a meta-analysis of prospective cohort studies. RESEARCH DESIGN AND METHODS:We conducted a PubMed databa...

journal_title：Diabetes care

authors： Dong JY,Xun P,He K,Qin LQ

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Studies comparing the incidence of blindness in persons with and without diabetes are scarce worldwide. In Germany, a decline in the incidence of blindness was found during the 1990s. The aim of this study was to analyze the recent time trend. RESEARCH DESIGN AND METHODS:Data were based on administrative fil...

journal_title：Diabetes care

authors： Claessen H,Kvitkina T,Narres M,Trautner C,Zöllner I,Bertram B,Icks A

更新日期：2018-03-01 00:00:00

abstract：:There was a need to design a questionnaire that could accurately assess the activity patterns of Native Americans to evaluate the relationship between physical activity and diabetes. Such a questionnaire was developed and implemented into the data collection scheme of the prospective Pima Indian Study of Arizona. The ...

journal_title：Diabetes care

authors： Kriska AM,Knowler WC,LaPorte RE,Drash AL,Wing RR,Blair SN,Bennett PH,Kuller LH

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:To determine whether evidence-based socioculturally adapted collaborative depression care improves receipt of depression care and depression and diabetes outcomes in low-income Hispanic subjects. RESEARCH DESIGN AND METHODS:This was a randomized controlled trial of 387 diabetic patients (96.5% Hispanic) with...

journal_title：Diabetes care

authors： Ell K,Katon W,Xie B,Lee PJ,Kapetanovic S,Guterman J,Chou CP

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:Many patients with early diabetes remain untreated. Our objectives were to identify clinical predictors of 1) worsening glycemic control and 2) medical treatment initiation in response to worsening glycemic control among patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:We identified 5,804 type 2 di...

journal_title：Diabetes care

authors： Pani LN,Nathan DM,Grant RW

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To estimate the incidence of type 2 diabetes in children <17 years of age and to investigate the relationship of diabetes with increasing childhood obesity in the U.K. and the Republic of Ireland (ROI). RESEARCH DESIGN AND METHODS:Active monthly reporting of cases by consultant pediatricians occurred through...

journal_title：Diabetes care

authors： Haines L,Wan KC,Lynn R,Barrett TG,Shield JP

更新日期：2007-05-01 00:00:00

abstract：:Due to the inherent pharmacokinetic properties of available insulins, normoglycemia is rarely, if ever, achieved in insulin-dependent diabetic patients without compromising their quality of life. Subcutaneous insulin absorption is influenced by many factors, among which the associated state of insulin (hexameric) in p...

journal_title：Diabetes care

authors： Brange J,Owens DR,Kang S,Vølund A

更新日期：1990-09-01 00:00:00

abstract：:Patients with diabetes mellitus may have any one of several forms of hypertension. These include essential hypertension, systolic hypertension of three varieties, the hypertension associated with diabetic nephropathy ("diabetic hypertension"), and the hypertension associated with neuropathy (supine hypertension with o...

journal_title：Diabetes care

authors： Christlieb AR

更新日期：1982-01-01 00:00:00