Clinical predictors of disease progression and medication initiation in untreated patients with type 2 diabetes and A1C less than 7%.

abstract：OBJECTIVE:Bariatric surgery may induce remission of type 2 diabetes in obese patients. However, estimates of remission rates reported in the literature range from 25 to 81%, contributing to the uncertainty patients and physicians both face as they assess treatment options. This analysis attempts to reconcile the seemin...

journal_title：Diabetes care

authors： Isaman DJ,Rothberg AE,Herman WH

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Cardiomyopathy is noted in up to 40% of infants of diabetic mothers, and the exact mechanisms are unknown. The aim of this study was to determine whether fetal serum markers of cardiac function differ between normal and type 1 diabetic pregnancies and to examine the relationship between these markers and feta...

journal_title：Diabetes care

authors： Russell NE,Higgins MF,Amaruso M,Foley M,McAuliffe FM

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To describe the changes in serum levels of calcitonin in liraglutide- and placebo-treated patients in the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results-A Long Term Evaluation (LEADER) trial over a 3.5-5-year period. RESEARCH DESIGN AND METHODS:Patients (n = 9,340) wi...

journal_title：Diabetes care

authors： Hegedüs L,Sherman SI,Tuttle RM,von Scholten BJ,Rasmussen S,Karsbøl JD,Daniels GH,LEADER Publication Committee on behalf of the LEADER Trial Investigators.

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes mellitus causes increased carotid intima-media thickness (IMT) in adults. We evaluated IMT in young subjects with type 1 diabetes. RESEARCH DESIGN AND METHODS:Participants with type 1 diabetes (N = 402) were matched to controls (N = 206) by age, sex, and race or ethnicity. Anthropometric and ...

journal_title：Diabetes care

authors： Urbina EM,Dabelea D,D'Agostino RB Jr,Shah AS,Dolan LM,Hamman RF,Daniels SR,Marcovina S,Wadwa RP

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To provide information about possible subclinical damage of the cochlear outer hair cells (OHCs) by means of transiently evoked otoacoustic emissions (TEOAEs) and distortion-product otoacoustic emissions (DPOAEs) in subjects with IDDM. RESEARCH DESIGN AND METHODS:TEOAEs and DPOAEs were recorded in 47 IDDM pa...

journal_title：Diabetes care

authors： Di Nardo W,Ghirlanda G,Paludetti G,Cercone S,Saponara C,Del Ninno M,Di Girolamo S,Magnani P,Di Leo MA

更新日期：1998-08-01 00:00:00

abstract：:Secondary failure to oral hypoglycemic agents (OHAs) is a possible outcome for non-insulin-dependent diabetes mellitus (NIDDM) patients and poses a serious therapeutic problem. In this study, we evaluated the effect of adding a single bedtime low-dose NPH insulin injection to the previous ineffective sulfonylurea ther...

journal_title：Diabetes care

authors： Trischitta V,Italia S,Borzi V,Tribulato A,Mazzarino S,Squatrito S,Vigneri R

更新日期：1989-09-01 00:00:00

abstract：:We describe affinity sensors for monitoring various metabolites in blood plasma by optical means. The principle of detection is similar to that used in radioimmunoassays and is based on the competitive binding of a particular metabolite and a fluorescein-labeled analogue with receptor sites specific for the metabolite...

journal_title：Diabetes care

authors： Schultz JS,Mansouri S,Goldstein IJ

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:To evaluate safety and efficacy of DiaPep277 in preserving β-cell function in type 1 diabetic patients. RESEARCH DESIGN AND METHODS:DIA-AID 1 is a multinational, phase 3, balanced-randomized, double-blind, placebo-controlled, parallel-group clinical study. Newly diagnosed patients (N = 457, aged 16-45 years)...

journal_title：Diabetes care

authors： Raz I,Ziegler AG,Linn T,Schernthaner G,Bonnici F,Distiller LA,Giordano C,Giorgino F,de Vries L,Mauricio D,Procházka V,Wainstein J,Elias D,Avron A,Tamir M,Eren R,Peled D,Dagan S,Cohen IR,Pozzilli P,DIA-AID 1 Writin

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Diabetes is a major predictor of death from heart disease and stroke; its impact on nonvascular mortality, including specific cancers, is less understood. We examined the association of diabetes with cause-specific mortality, including deaths from specific cancers. RESEARCH DESIGN AND METHODS:A prospective c...

journal_title：Diabetes care

authors： Campbell PT,Newton CC,Patel AV,Jacobs EJ,Gapstur SM

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of IGT and diabetes and identify the occurrence of CVD and its risk factors. RESEARCH DESIGN AND METHODS:This study was a population-based, cross-sectional study of 110,660 residents, 25-74 yr of age of DaQing, Hei Long Jiang Province, China. RESULTS:Using 1985 WHO criteria, 577 ...

journal_title：Diabetes care

authors： Pan XR,Hu YH,Li GW,Liu PA,Bennett PH,Howard BV

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:Diet is the cornerstone treatment of patients with gestational diabetes mellitus (GDM), but its role in maternal and newborn outcomes has been scarcely studied. The purpose of this study was to analyze the efficacy of dietary interventions on maternal or newborn outcomes in patients with GDM. RESEARCH DESIGN...

journal_title：Diabetes care

authors： Viana LV,Gross JL,Azevedo MJ

更新日期：2014-12-01 00:00:00

abstract：:Pregnancy induces complex changes in energy metabolism, manifested clinically by insulin resistance, low fasting blood glucose levels, and proneness to ketosis. It is quite unusual for pregnant women who do not have type I diabetes to progress from ketosis to frank ketoacidosis, although this phenomenon is common in l...

journal_title：Diabetes care

authors： Bedalov A,Balasubramanyam A

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of new insulin glargine 300 units/mL (Gla-300) with glargine 100 units/mL (Gla-100) in people with type 2 diabetes on basal insulin (≥42 units/day) plus mealtime insulin. RESEARCH DESIGN AND METHODS:EDITION 1 (NCT01499082) was a 6-month, multinational, open-label, parallel-...

journal_title：Diabetes care

authors： Riddle MC,Bolli GB,Ziemen M,Muehlen-Bartmer I,Bizet F,Home PD,EDITION 1 Study Investigators.

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Individuals with type 2 diabetes have high risk of late-life cognitive impairment, yet little is known about strategies to modify risk. Targeting insulin resistance and vascular complications-both associated with cognitive decline-may be a productive approach. We investigated whether dietary fat, which modula...

journal_title：Diabetes care

authors： Devore EE,Stampfer MJ,Breteler MM,Rosner B,Kang JH,Okereke O,Hu FB,Grodstein F

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To determine the incidence of insulin-dependent diabetes mellitus (IDDM) in children aged 0-14 years in Kuwait, as part of the World Health Organization Multinational Collaborative Study (DIAMOND), and to determine if the incidence rates have increased. RESEARCH DESIGN AND METHODS:All cases of IDDM diagnosed...

journal_title：Diabetes care

authors： Shaltout AA,Qabazard MA,Abdella NA,LaPorte RE,al Arouj M,Ben Nekhi A,Moussa MA,al Khawari MA

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:Newer medications offer more options for glycemic control in type 2 diabetes. However, they come at considerable costs. We undertook a health economic analysis to better understand the value of adding two newer medications (exenatide and sitagliptin) as second-line therapy to glycemic control strategies for p...

journal_title：Diabetes care

authors： Sinha A,Rajan M,Hoerger T,Pogach L

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine whether high levels of HDL cholesterol are associated with a lower prevalence of albuminuria RESEARCH DESIGN AND METHODS:We analyzed the lipid profiles of patients with type 1 diabetes of > or = 20 years duration in 42 patients with albuminuria (28 microalbuminuri...

journal_title：Diabetes care

authors： Molitch ME,Rupp D,Carnethon M

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To investigate the influence of the insertion/deletion polymorphism of the ACE gene on the progression of early diabetic glomerulopathy in patients with and without antihypertensive treatment (AHT). RESEARCH DESIGN AND METHODS:There were 30 microalbuminuric patients with >5 years of type 1 diabetes who had r...

journal_title：Diabetes care

authors： Rudberg S,Rasmussen LM,Bangstad HJ,Osterby R

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:Previous studies have provided inconclusive results on the role of uric acid (UA) in risk prediction. Here we aimed to improve the power and precision of the predictive value of UA for the risk of decline in kidney function, cardiovascular events (CVEs), and mortality in patients with type 1 diabetes (T1D). ...

journal_title：Diabetes care

authors： Pilemann-Lyberg S,Hansen TW,Tofte N,Winther SA,Theilade S,Ahluwalia TS,Rossing P

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To determine the best autoantibody-based testing strategy for recruiting relatives for future intervention trials and to establish the role of islet cell antibodies (ICAs) within this strategy. RESEARCH DESIGN AND METHODS:ICAs, insulin autoantibodies (IAAs), GAD antibodies, and IA-2 antibodies were determine...

journal_title：Diabetes care

authors： Bingley PJ,Williams AJ,Gale EA

更新日期：1999-11-01 00:00:00

abstract：:A case-control study examining the 1-yr motor vehicle accident experiences of 158 insulin-dependent diabetes mellitus (IDDM) cases and 158 nondiabetic siblings was undertaken to evaluate the risk of motor vehicle accidents among drivers with IDDM. In multivariate analyses the overall accident risk of the cases and con...

journal_title：Diabetes care

authors： Songer TJ,LaPorte RE,Dorman JS,Orchard TJ,Cruickshanks KJ,Becker DJ,Drash AL

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of glyburide versus metformin and their combination for the treatment of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:In this prospective randomized controlled study, we randomly assigned patients with GDM at 13-33 weeks gestation and whose blood glucose...

journal_title：Diabetes care

authors： Nachum Z,Zafran N,Salim R,Hissin N,Hasanein J,Gam Ze Letova Y,Suleiman A,Yefet E

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To compare pharmacokinetics (PK) and pharmacodynamics (PD) of insulin glargine in type 2 diabetes mellitus (T2DM) after evening versus morning administration. RESEARCH DESIGN AND METHODS:Ten T2DM insulin-treated persons were studied during 24-h euglycemic glucose clamp, after glargine injection (0.4 units/kg...

journal_title：Diabetes care

authors： Porcellati F,Lucidi P,Cioli P,Candeloro P,Marinelli Andreoli A,Marzotti S,Ambrogi M,Bolli GB,Fanelli CG

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To determine 1) whether participants in the Spanish Diabetes Self-Management Program (SDSMP), when compared at 6 months to randomized control subjects, would demonstrate improvements in health status, health behaviors, and self-efficacy; and 2) whether SDSMP participants receiving monthly automated telephone ...

journal_title：Diabetes care

authors： Lorig K,Ritter PL,Villa F,Piette JD

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between metformin use and anemia risk in type 2 diabetes, and the time-course for this, in a randomized controlled trial (RCT) and real-world population data. RESEARCH DESIGN AND METHODS:Anemia was defined as a hemoglobin measure of <11 g/dL. In the RCTs A Diabetes Outcome Progres...

journal_title：Diabetes care

authors： Donnelly LA,Dennis JM,Coleman RL,Sattar N,Hattersley AT,Holman RR,Pearson ER

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To study the effect of vitamin E supplementation on platelet hyperaggregability in type 1 diabetic patients. RESEARCH DESIGN AND METHODS:Written informed consent according to the Institutional Review Board on Human Experimentation guidelines was obtained from diabetic patients (n = 29) and their age-matched ...

journal_title：Diabetes care

authors： Jain SK,Krueger KS,McVie R,Jaramillo JJ,Palmer M,Smith T

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:Platelet hyperfunction is a typical feature of the prothrombotic state that frequently complicates the natural history of diabetes. In uremia, a bleeding diathesis is present, which principally involves the primary phase of hemostasis. Thus, in patients with uremia of diabetic origin, the infrequent coexisten...

journal_title：Diabetes care

authors： Vicari AM,Taglietti MV,Pellegatta F,Spotti D,Melandri M,Galli L,Ronchi P,Folli F

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence of diabetes and prediabetes and the associated risk factors in two Asian Indian populations living in different environments. RESEARCH DESIGN AND METHODS:We performed cross-sectional analyses, using representative samples of 2,305 Asian Indians aged 40-84 years living in Chennai, Ind...

journal_title：Diabetes care

authors： Gujral UP,Narayan KM,Pradeepa RG,Deepa M,Ali MK,Anjana RM,Kandula NR,Mohan V,Kanaya AM

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To describe the association between Bacille Calmette-Guérin (BCG) vaccination and IDDM development in two different case-control series (A and B) in Montreal. RESEARCH DESIGN AND METHODS:Case-control series A comprised 93 IDDM cases and 2,903 control subjects who participated in a community-based tuberculin ...

journal_title：Diabetes care

authors： Parent ME,Siemiatycki J,Menzies R,Fritschi L,Colle E

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To provide evidence-based options on how to intensify basal insulin, we explored head-to-head prandial interventions in overweight patients with type 2 diabetes inadequately controlled on basal insulin glargine with or without 1-3 oral antidiabetic agents (OADs). RESEARCH DESIGN AND METHODS:Patients were ran...

journal_title：Diabetes care

authors： Rosenstock J,Guerci B,Hanefeld M,Gentile S,Aronson R,Tinahones FJ,Roy-Duval C,Souhami E,Wardecki M,Ye J,Perfetti R,Heller S,GetGoal Duo-2 Trial Investigators.

更新日期：2016-08-01 00:00:00