Costs and consequences associated with newer medications for glycemic control in type 2 diabetes.

abstract：OBJECTIVE:We investigated the efficacy and safety of the sodium glucose cotransporter 2 inhibitor, empagliflozin, added to multiple daily injections of insulin (MDI insulin) in obese patients with type 2 diabetes mellitus (T2DM). RESEARCH DESIGN AND METHODS:Patients inadequately controlled on MDI insulin ± metformin (...

journal_title：Diabetes care

authors： Rosenstock J,Jelaska A,Frappin G,Salsali A,Kim G,Woerle HJ,Broedl UC,EMPA-REG MDI Trial Investigators.

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To assess the performance of the Micral-Test II immunologic test strip for the detection of microalbuminuria, a multicenter evaluation in eight European study sites was performed. RESEARCH DESIGN AND METHODS:Using both the Micral-Test II test strip and the routine method for the determination of albumin conc...

journal_title：Diabetes care

authors： Mogensen CE,Viberti GC,Peheim E,Kutter D,Hasslacher C,Hofmann W,Renner R,Bojestig M,Poulsen PL,Scott G,Thoma J,Kuefer J,Nilsson B,Gambke B,Mueller P,Steinbiss J,Willamowski KD

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the association between foot ulcers (DFU) and lower-extremity amputation (LEA) and chronic kidney disease (CKD) in patients with diabetes. RESARCH DESIGN AND METHODS: This was a retrospective cohort study of individuals enrolled between 2002 and 2006 who were aged >...

journal_title：Diabetes care

authors： Margolis DJ,Hofstad O,Feldman HI

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:The Hawaii IDDM Registry was created to determine the incidence rate of IDDM among children aged < 15 years of Oahu between 1980 and 1990. Because of the multiracial population living in Hawaii, it is an ideal state in which to study the effect of migration on IDDM incidence. RESEARCH DESIGN AND METHODS:Data...

journal_title：Diabetes care

authors： Patrick SL,Kadohiro JK,Waxman SH,Curb JD,Orchard TJ,Dorman JS,Kuller LH,LaPorte RE

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:A1C is associated with diabetes complications but does not reflect glycemic variability (GV), which may worsen outcomes by inducing inflammation, oxidative stress, and cardiac arrhythmias. We tested whether a glucagon-like peptide 1 agonist-based regimen can reduce GV and cardiometabolic risk markers while ma...

journal_title：Diabetes care

authors： FLAT-SUGAR Trial Investigators.

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To characterize metabolic effects of troglitazone in type 2 diabetic, obese, and lean subjects, and examine the effects of troglitazone 2-3 weeks after discontinuation. RESEARCH DESIGN AND METHODS:Nine type 2 diabetic, nine obese, and nine lean subjects underwent baseline metabolic studies including an 8-h m...

journal_title：Diabetes care

authors： Frias JP,Yu JG,Kruszynska YT,Olefsky JM

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:In adults with diabetes, in vivo platelet activation is a marker for atherosclerosis and cardiovascular disease (CVD). This pilot study investigated whether adolescents with diabetes had evidence of increased in vivo platelet activation. RESEARCH DESIGN AND METHODS:In vivo platelet activation was compared in...

journal_title：Diabetes care

authors： Israels SJ,McNicol A,Dean HJ,Cognasse F,Sellers EA

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Identifying maturity-onset diabetes of the young (MODY) in pediatric populations close to diabetes diagnosis is difficult. Misdiagnosis and unnecessary insulin treatment are common. We aimed to identify the discriminatory clinical features at diabetes diagnosis of patients with glucokinase (GCK), hepatocyte n...

journal_title：Diabetes care

authors： Carlsson A,Shepherd M,Ellard S,Weedon M,Lernmark Å,Forsander G,Colclough K,Brahimi Q,Valtonen-Andre C,Ivarsson SA,Elding Larsson H,Samuelsson U,Örtqvist E,Groop L,Ludvigsson J,Marcus C,Hattersley AT

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:In children with type 1 diabetes (T1D), severe hypoglycemia (SH) is associated with poorer cognition, but the association of SH with cognitive function in late life is unknown. Given the increasing life expectancy in people with T1D, understanding the role of SH in brain health is crucial. RESEARCH DESIGN AN...

journal_title：Diabetes care

authors： Lacy ME,Gilsanz P,Eng C,Beeri MS,Karter AJ,Whitmer RA

更新日期：2020-03-01 00:00:00

abstract：:Twenty-nine diabetic renal failure patients suffered a psychosocial crisis at the time when chronic dialysis or renal transplantation was required. These patients could be classified into groups as to the impact of the crisis in terms of participation in life-support therapy. Group 1 consisted of potentially lethal me...

journal_title：Diabetes care

authors： D'Elia JA,Piening S,Kaldany A,Malarick C,Unger K,Ice S,Anderson RB,Miller DG,Lundin AP

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:Screening involves the presumptive identification of asymptomatic individuals at increased risk for unrecognized disease. We examined changes in screening practices for prediabetes and diabetes since January 2010, when HbA1c was first recommended as an option for screening and diagnosis. RESEARCH DESIGN AND ...

journal_title：Diabetes care

authors： Evron JM,Herman WH,McEwen LN

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Thiazolidinediones (TZDs) and metformin are insulin-sensitizing antihyperglycemic agents with reported benefits on atherosclerosis. Despite extensive use in patients with diabetes and cardiovascular disease, there is a paucity of outcomes data with metformin and none yet with TZDs. We sought to determine the ...

journal_title：Diabetes care

authors： Inzucchi SE,Masoudi FA,Wang Y,Kosiborod M,Foody JM,Setaro JF,Havranek EP,Krumholz HM

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:This study examined whether lipids modify the relationship between intensive glucose control (INT) and diabetic retinopathy (DR). RESEARCH DESIGN AND METHODS:The incidence and progression of DR were assessed in 858 of 1,791 participants with 7-field stereoscopic fundus photographs at baseline and 5 years lat...

journal_title：Diabetes care

authors： Azad N,Bahn GD,Emanuele NV,Agrawal L,Ge L,Reda D,Klein R,Reaven PD,Hayward R,VADT Study Group.

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To test whether diabetic polyneuropathies (DPNs), retinopathy, or nephropathy is more prevalent in subjects with impaired glycemia (IG) (abnormality of impaired fasting glucose [IFG], impaired glucose tolerance [IGT], or impaired HbA(1c) [IA1C]) than in healthy subjects (non-IG). RESEARCH DESIGN AND METHODS:...

journal_title：Diabetes care

authors： Dyck PJ,Clark VM,Overland CJ,Davies JL,Pach JM,Dyck PJ,Klein CJ,Rizza RA,Melton LJ 3rd,Carter RE,Klein R,Litchy WJ

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:Our aim was to analyze the performance of two scores developed for predicting diabetes in nontransplant populations for identifying kidney transplant recipients with a higher new-onset diabetes mellitus after transplantation (NODAT) risk beyond the first year after transplantation. RESEARCH DESIGN AND METHOD...

journal_title：Diabetes care

authors： Rodrigo E,Santos L,Piñera C,Millán JC,Quintela ME,Toyos C,Allende N,Gómez-Alamillo C,Arias M

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:While there is growing evidence on the effectiveness of structured care for diabetic patients in trial settings, standard population level evaluations may misestimate intervention benefits due to patient selection. In order to account for potential biases in measuring intervention benefits, we tested the impa...

journal_title：Diabetes care

authors： Chevreul K,Brunn M,Cadier B,Nolte E,Durand-Zaleski I

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Preanalytical processing of blood samples can affect plasma glucose measurement because ongoing glycolysis by cells prior to centrifugation can lower its concentration. In June 2017, ACT Pathology changed the processing of oral glucose tolerance test (OGTT) blood samples for pregnant women from a delayed to a...

journal_title：Diabetes care

authors： Potter JM,Hickman PE,Oakman C,Woods C,Nolan CJ

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the temporal patterns of cardiometabolic multimorbidity (CM) and depression in White Caucasians (WCs) and African Americans (AAs) with early-onset type 2 diabetes and their impact on long-term atherosclerotic cardiovascular disease (ASCVD). RESEARCH DESIGN AND METHODS:From U.S. electronic medical...

journal_title：Diabetes care

authors： Dibato JE,Montvida O,Zaccardi F,Sargeant JA,Davies MJ,Khunti K,Paul SK

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Individuals with impaired glucose tolerance (IGT) are at high risk for developing type 2 diabetes mellitus (T2DM). We examined which characteristics at baseline predicted the development of T2DM versus maintenance of IGT or conversion to normal glucose tolerance. RESEARCH DESIGN AND METHODS:We studied 228 su...

journal_title：Diabetes care

authors： Defronzo RA,Tripathy D,Schwenke DC,Banerji M,Bray GA,Buchanan TA,Clement SC,Henry RR,Kitabchi AE,Mudaliar S,Ratner RE,Stentz FB,Musi N,Reaven PD,Gastaldelli A,ACT NOW Study.

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:N-acetylglucosamine/galactosamine (GlycA) and sialic acid (GlycB) moieties of glycosylated serum proteins are nonspecific measures of inflammation, but conclusive data on their relationship with insulin resistance or insulin secretion are missing. Therefore, we aimed to examine the relation of GlycA, GlycB, a...

journal_title：Diabetes care

authors： Lorenzo C,Festa A,Hanley AJ,Rewers MJ,Escalante A,Haffner SM

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of systemic hyperbaric oxygen therapy (s HBOT) in addition to a comprehensive protocol in decreasing major amputation rate in diabetic patients hospitalized for severe foot ulcer. RESEARCH DESIGN AND METHODS:From August 1993 to August 1995, 70 diabetic subjects were consecutivel...

journal_title：Diabetes care

authors： Faglia E,Favales F,Aldeghi A,Calia P,Quarantiello A,Oriani G,Michael M,Campagnoli P,Morabito A

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy, safety, and compliance of a nonremovable fiberglass cast boot and off-loading shoes in the treatment of diabetic plantar ulcers. RESEARCH DESIGN AND METHODS:Patients (n = 93) with noninfected, nonischemic plantar ulcers were included in this prospective nonrandomized study. Treatment...

journal_title：Diabetes care

authors： Ha Van G,Siney H,Hartmann-Heurtier A,Jacqueminet S,Greau F,Grimaldi A

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To determine whether food insecurity--the inability to reliably afford safe and nutritious food--is associated with poor glycemic control and whether this association is mediated by difficulty following a healthy diet, diabetes self-efficacy, or emotional distress related to diabetes. RESEARCH DESIGN AND MET...

journal_title：Diabetes care

authors： Seligman HK,Jacobs EA,López A,Tschann J,Fernandez A

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:To quantify age-related variability of insulin needs during day and night closed-loop insulin delivery. RESEARCH DESIGN AND METHODS:We retrospectively analyzed data from hybrid closed-loop studies involving young children (1-6 years old, n = 20), children (7-12 years, n = 21), adolescents (13-17 years, n = 1...

journal_title：Diabetes care

authors： Dovc K,Boughton C,Tauschmann M,Thabit H,Bally L,Allen JM,Acerini CL,Arnolds S,de Beaufort C,Bergenstal RM,Campbell F,Criego A,Dunger DB,Elleri D,Evans ML,Fröhlich-Reiterer E,Hofer S,Kapellen T,Leelarathna L,Pieber T

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To determine whether perceived risk and other health beliefs held by individuals at high risk for developing NIDDM predict weight loss and behavior change during a behavioral weight loss program to reduce the risk of NIDDM. RESEARCH DESIGN AND METHODS:Health beliefs and objective risk factors for diabetes we...

journal_title：Diabetes care

authors： Polley BA,Jakicic JM,Venditti EM,Barr S,Wing RR

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:To assess the relevance of pulse pressure as a predictor of foot ulcers in type 2 diabetic subjects. RESEARCH DESIGN AND METHODS:A cohort study was performed on a consecutive series of 1,945 type 2 diabetic outpatients without a foot ulcer at baseline. Incident foot ulcers were identified through the regiona...

journal_title：Diabetes care

authors： Monami M,Vivarelli M,Desideri CM,Colombi C,Marchionni N,Mannucci E

更新日期：2009-05-01 00:00:00

abstract：:The results of uncontrolled trials in immunomodulation of insulin-dependent diabetes mellitus (IDDM) led to randomized controlled trials in Canada and Europe. In the Canadian open study, the rate of clinical remissions (target control of glycemia maintained with less than or equal to 0.15 U.kg-1.day-1 insulin) was une...

journal_title：Diabetes care

authors： Dupré J,Stiller CR,Gent M,Donner A,von Graffenried B,Heinrichs D,Jenner M,Keown P,Mahon J,Martell R

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVE:Subjects with type 1 diabetes are at high risk for many long-term complications, including early mortality and coronary artery disease (CAD). Few data are available on which to base goal levels for two major risk factors, namely blood pressure and lipid/lipoproteins. The objective of this study was to determi...

journal_title：Diabetes care

authors： Orchard TJ,Forrest KY,Kuller LH,Becker DJ,Pittsburgh Epidemiology of Diabetes Complications Study.

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:In the French Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort, cross-sectional analyses have shown that a higher consumption of dairy products and calcium are associated with a lower prevalence of the metabolic syndrome (MetS). We assess the influence of dairy products on...

journal_title：Diabetes care

authors： Fumeron F,Lamri A,Abi Khalil C,Jaziri R,Porchay-Baldérelli I,Lantieri O,Vol S,Balkau B,Marre M,Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Study Group.

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess racial/ethnic variation in access to health care, use of particular health care services, presence of cardiovascular risk factors, and perceptions of health and impairment among women at risk for type 2 diabetes because of their histories of gestational diabetes mellitu...

journal_title：Diabetes care

authors： Kim C,Sinco B,Kieffer EA

更新日期：2007-06-01 00:00:00