Decreased polymorphonuclear leukocyte deformability in NIDDM.

abstract：OBJECTIVE:To promote foot screening of inpatients with diabetes, we simplified sensory testing to lightly touching the tips of the first, third, and fifth toes (the Ipswich Touch Test [IpTT]). RESEARCH DESIGN AND METHODS:Respective performances of the IpTT and 10-g monofilament (MF) were compared with a vibration perc...

journal_title：Diabetes care

authors： Rayman G,Vas PR,Baker N,Taylor CG Jr,Gooday C,Alder AI,Donohoe M

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:Continuous glucose monitoring (CGM) reduces HbA1c and time spent in hypoglycemia in people with type 1 diabetes (T1D) treated with multiple daily insulin injections (MDI) when evaluated over shorter time periods. It is unclear to what extent CGM improves and helps to maintain glucose control, treatment satisf...

journal_title：Diabetes care

authors： Lind M,Ólafsdóttir AF,Hirsch IB,Bolinder J,Dahlqvist S,Pivodic A,Hellman J,Wijkman M,Schwarcz E,Albrektsson H,Heise T,Polonsky W

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To test the psychometric properties of the short form of the Chinese version Diabetes Quality of Life for Youth scale (C-DQOLY-SF). RESEARCH DESIGN AND METHODS:A 30-item C-DQOLY-SF was administered to 371 adolescents with type 1 diabetes. Exploratory and confirmatory factor analysis, correlation with HbA(1c)...

journal_title：Diabetes care

authors： Wang RH,Lo FS,Chen BH,Hsu HY,Lee YJ

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Type 2 diabetes mellitus (T2DM) is associated with dyslipidemia, but the detailed alterations in lipid species preceding the disease are largely unknown. We aimed to identify plasma lipids associated with development of T2DM and investigate their associations with lifestyle. RESEARCH DESIGN AND METHODS:At ba...

journal_title：Diabetes care

authors： Fernandez C,Surma MA,Klose C,Gerl MJ,Ottosson F,Ericson U,Oskolkov N,Ohro-Melander M,Simons K,Melander O

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:Evidence that midregional fragment of pro-A-type natriuretic peptide (MR-proANP) is a marker of mortality in patients with type 2 diabetes is limited. Therefore, we aimed to investigate the capabilities of MR-proANP in predicting mortality. We also investigated whether MR-proANP influences the relationship be...

journal_title：Diabetes care

authors： van Hateren KJ,Landman GW,Kleefstra N,Groenier KH,Struck J,Navis GJ,Bakker SJ,Houweling ST,van der Meer K,Bilo HJ

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Given the role of gut microbiota in regulating metabolism, probiotics administered during pregnancy might prevent gestational diabetes mellitus (GDM). This question has not previously been studied in high-risk overweight and obese pregnant women. We aimed to determine whether probiotics (Lactobacillus rhamnos...

journal_title：Diabetes care

authors： Callaway LK,McIntyre HD,Barrett HL,Foxcroft K,Tremellen A,Lingwood BE,Tobin JM,Wilkinson S,Kothari A,Morrison M,O'Rourke P,Pelecanos A,Dekker Nitert M

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:To develop and validate a scale for acanthosis nigricans (AN). RESEARCH DESIGN AND METHODS:Subjects were participants from the San Antonio Family Diabetes Study and the San Antonio Family Heart Study. A total of 406 subjects were independently examined for AN by at least two observers. Five locations were ex...

journal_title：Diabetes care

authors： Burke JP,Hale DE,Hazuda HP,Stern MP

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of a telephone-delivered behavioral weight loss and physical activity intervention targeting Australian primary care patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:Pragmatic randomized controlled trial of telephone counseling (n = 151) versus usual care (n = 151). Re...

journal_title：Diabetes care

authors： Eakin EG,Winkler EA,Dunstan DW,Healy GN,Owen N,Marshall AM,Graves N,Reeves MM

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Individuals with type 2 diabetes are particularly vulnerable to cardiovascular disease. Insulin resistance is a major determinant of this increased risk and is a potential therapeutic target. This study was undertaken to establish the natural biological variation of insulin resistance in individuals with type...

journal_title：Diabetes care

authors： Jayagopal V,Kilpatrick ES,Jennings PE,Hepburn DA,Atkin SL

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:The results differ concerning randomized controlled trials of the effects of metformin on blood glucose regulation and body weight. To get a systematic overview, a meta-analysis of the efficacy of metformin was performed by comparing metformin with placebo and sulfonylurea. RESEARCH DESIGN AND METHODS:All ra...

journal_title：Diabetes care

authors： Johansen K

更新日期：1999-01-01 00:00:00

abstract：:Considerable attention has been focused on the importance of physical activity in improving the diabetic state in obese, non-insulin-dependent diabetic patients. Because this patient population tends to be sedentary, this challenge requires an active effort involving the patient and health-care providers. The latter m...

journal_title：Diabetes care

authors： Beeken RK

更新日期：1980-09-01 00:00:00

abstract：:This study investigates and compares human insulin (recombinant DNA) and purified porcine insulin (PPI) in healthy volunteers and in type II diabetic patients, in terms of whether both these insulins were capable of influencing in a different manner pancreatic glucagon, C-peptide, and free fatty acids (FFA) concentrat...

journal_title：Diabetes care

authors： Raptis S,Hadjidakis D,Enzmann F,Raptis A,Diamantopoulos E,Rosenthal J

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:This study assessed the ability to distinguish between type 1 diabetes-affected individuals and their unaffected relatives using HLA and single nucleotide polymorphism (SNP) genotypes. RESEARCH DESIGN AND METHODS:Eight models, ranging from only the high-risk DR3/DR4 genotype to all significantly associated H...

journal_title：Diabetes care

authors： Valdes AM,Varney MD,Erlich HA,Noble JA

更新日期：2013-09-01 00:00:00

abstract：:We measured plasma lipid and lipoprotein levels at baseline and at 6-mo intervals in 47 normolipidemic patients with classic insulin-dependent diabetes mellitus treated either with a conventional (n = 21) or intensive (n = 26) diabetes-treatment program. Patients were followed for a mean of 3 yr (range 1-4 yr). Intens...

journal_title：Diabetes care

authors： Rosenstock J,Strowig S,Cercone S,Raskin P

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and relative risk of type 2 diabetes defined by the newly proposed HbA(1c) diagnostic criteria in groups categorized by different baseline HbA(1c) levels. RESEARCH DESIGN AND METHODS:Using data from the European Prospective Investigation of Cancer (EPIC)-Norfolk cohort with repeat H...

journal_title：Diabetes care

authors： Chamnan P,Simmons RK,Forouhi NG,Luben RN,Khaw KT,Wareham NJ,Griffin SJ

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate the rate of progression of nonalbuminuric chronic kidney disease (CKD) to end-stage kidney disease (ESKD) or death or major cardiovascular events (MACE) compared with albuminuric and nonalbuminuric phenotypes. RESEARCH DESIGN AND METHODS:We included 10,185 participants with type 2 dia...

journal_title：Diabetes care

authors： Buyadaa O,Magliano DJ,Salim A,Koye DN,Shaw JE

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Uncertainty remains regarding the predictive value of various glycemic measures as they relate to the risk of diabetes and its complications. Using the cutoffs recommended by the American Diabetes Association's 2010 criteria, we determined the associations of fasting plasma glucose (FPG), 2-h postload glucose...

journal_title：Diabetes care

authors： Lu J,He J,Li M,Tang X,Hu R,Shi L,Su Q,Peng K,Xu M,Xu Y,Chen Y,Yu X,Yan L,Wang T,Zhao Z,Qin G,Wan Q,Chen G,Dai M,Zhang D,Gao Z,Wang G,Shen F,Luo Z,Qin Y,Chen L,Huo Y,Li Q,Ye Z,Zhang Y,Du R,Che

更新日期：2019-08-01 00:00:00

abstract：:OBJECTIVE We tested whether average monthly glycemic burden (AMGB), a marker of hyperglycemia that is a function of the extent and duration that A1C exceeded 7%, indicated greater risk of cardiovascular disease (CVD) than traditional A1C measures. RESEARCH DESIGN AND METHODS Using a case-control design, we studied 2,4...

journal_title：Diabetes care

authors： Nichols GA,Rosales AG,Perrin NA,Fortmann SP

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To determine maternal parameters with the strongest influence on fetal growth in different periods of pregnancies complicated by an abnormal glucose tolerance test (GTT). RESEARCH DESIGN AND METHODS:Retrospective study of 368 women with gestational diabetes mellitus (GDM; > or = 2 abnormal GTT values, n = 28...

journal_title：Diabetes care

authors： Schaefer-Graf UM,Kjos SL,Kilavuz O,Plagemann A,Brauer M,Dudenhausen JW,Vetter K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To determine whether skin intrinsic fluorescence (SIF) was associated with autonomic neuropathy and confirmed distal symmetrical polyneuropathy (CDSP) in 111 individuals with type 1 diabetes (mean age 49 years, mean diabetes duration 40 years). RESEARCH DESIGN AND METHODS:SIF was measured using the SCOUT DM ...

journal_title：Diabetes care

authors： Conway BN,Aroda VR,Maynard JD,Matter N,Fernandez S,Ratner RE,Orchard TJ

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To explore the nature of functional impairment in older people with diabetes. RESEARCH DESIGN AND METHODS:A population-based case-control study with detailed assessment of diabetes and functional status was undertaken. RESULTS:Altogether, 403 case subjects and 403 matched control subjects were studied (medi...

journal_title：Diabetes care

authors： Sinclair AJ,Conroy SP,Bayer AJ

更新日期：2008-02-01 00:00:00

abstract：:It would be advantageous to be able to measure glycosylated hemoglobin (GHb) from a sample of blood dried on paper and sent to the physician by the patient. Indeed, such a technique has been introduced by Isolab (Akron, OH). We tested the validity of the method to determine whether applying the blood to paper and imme...

journal_title：Diabetes care

authors： Broussolle C,Saudek CD

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:To understand why low-fat high-carbohydrate (CHO) diets lead to higher fasting and postprandial concentrations of triglyceride (TG)-rich lipoproteins in patients with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:Patients with NIDDM were placed randomly on diets containing eith...

journal_title：Diabetes care

authors： Chen YD,Coulston AM,Zhou MY,Hollenbeck CB,Reaven GM

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:To assess the level of serum lipoprotein(a) [Lp(a)] in nonobese and obese NIDDM subjects with android body distribution. RESEARCH DESIGN AND METHODS:Serum Lp(a) levels were measured in 30 long-standing NIDDM patients (duration of diabetes 12.5 +/- 3 years, mean +/- SD), with 15 of the patients being obese of...

journal_title：Diabetes care

authors： Wassef N,Sidhom G,Zakareya el-K,Mohamed el-K

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:In type 1 diabetes (T1D), the course of microalbuminuria is unpredictable and timing of glomerular filtration rate (GFR) loss is uncertain. Thus, there is a need to identify the risk factors associated with the development of more advanced stages of kidney disease through large, long-term systematic analysis....

journal_title：Diabetes care

authors： Perkins BA,Bebu I,de Boer IH,Molitch M,Tamborlane W,Lorenzi G,Herman W,White NH,Pop-Busui R,Paterson AD,Orchard T,Cowie C,Lachin JM,Diabetes Control and Complications Trial (DCCT)\/Epidemiology of Diabetes Interventions and Com

更新日期：2019-05-01 00:00:00

abstract：:Epidemiological studies performed over the past 40 years have shown that the prevalence of diagnosed diabetes has increased dramatically in the U.S. and that a substantial proportion of the population has undiagnosed diabetes, impaired fasting glucose, and impaired glucose tolerance. Diabetes is most prevalent in mino...

journal_title：Diabetes care

authors： Harris MI

更新日期：1998-12-01 00:00:00

abstract：:Since little is known regarding the appropriate time for preprandial insulin administration, we compared the effects of 30-min subcutaneous insulin infusions started 60 min, 30 min, and immediately before meal ingestion on postprandial plasma glucose and insulin profiles in eight subjects with insulin-dependent diabet...

journal_title：Diabetes care

authors： Dimitriadis GD,Gerich JE

更新日期：1983-07-01 00:00:00

abstract：OBJECTIVE:To create a simple prediction rule that could perform as well as the 2-h postchallenge plasma glucose (PCPG) test to predict those at risk for diabetes. We created a prediction rule in one sample and prospectively validated it for incident diabetes in a separate cohort. RESEARCH DESIGN AND METHODS:A cross-se...

journal_title：Diabetes care

authors： Kanaya AM,Wassel Fyr CL,de Rekeneire N,Shorr RI,Schwartz AV,Goodpaster BH,Newman AB,Harris T,Barrett-Connor E

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:Reduced heart rate variability (HRV) and increased heart rate (HR) have been associated with cardiovascular mortality. Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) increase HR, and studies have suggested that they may reduce HRV. We examined the effect of the GLP-1 RA liraglutide on HRV and diurnal v...

journal_title：Diabetes care

authors： Kumarathurai P,Anholm C,Larsen BS,Olsen RH,Madsbad S,Kristiansen O,Nielsen OW,Haugaard SB,Sajadieh A

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Cardiomyopathy is noted in up to 40% of infants of diabetic mothers, and the exact mechanisms are unknown. The aim of this study was to determine whether fetal serum markers of cardiac function differ between normal and type 1 diabetic pregnancies and to examine the relationship between these markers and feta...

journal_title：Diabetes care

authors： Russell NE,Higgins MF,Amaruso M,Foley M,McAuliffe FM

更新日期：2009-11-01 00:00:00