Acute effects of insulin in the control of VLDL production in humans. Implications for the insulin-resistant state.

abstract：OBJECTIVE:Therapies with metformin, sulfonylureas, or insulin improve glycemic control in the short term but do not prevent progressive islet beta-cell failure or long-term deterioration in glycemia. Our goal was to evaluate, in patients recently diagnosed with type 2 diabetes (<3 years), the long-term efficacy of mono...

journal_title：Diabetes care

authors： Viberti G,Kahn SE,Greene DA,Herman WH,Zinman B,Holman RR,Haffner SM,Levy D,Lachin JM,Berry RA,Heise MA,Jones NP,Freed MI

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To determine the short-term muscular endurance and working capacity of leg muscles in long-term IDDM patients in relation to neuropathic complications, muscle strength, and metabolic control. RESEARCH DESIGN AND METHODS:The muscular endurance of extensors and flexors at the ankle and knee was assessed in 44 ...

journal_title：Diabetes care

authors： Andersen H

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:Participants in ADVANCE were drawn from many countries. We examined whether the effects of intensive glycemic control on major outcomes in ADVANCE differ between participants from Asia, established market economies (EMEs), and eastern Europe. RESEARCH DESIGN AND METHODS:ADVANCE was a clinical trial of 11,140...

journal_title：Diabetes care

authors： Woodward M,Patel A,Zoungas S,Liu L,Pan C,Poulter N,Januszewicz A,Tandon N,Joshi P,Heller S,Neal B,Chalmers J

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Patients with diabetes have a higher case fatality rate in myocardial infarction (MI) or stroke than those without diabetes: that is, MI and stroke are more often fatal if diabetes is present. We investigated whether the risk of MI or stroke being fatal in type 2 diabetes can be estimated using information av...

journal_title：Diabetes care

authors： Stevens RJ,Coleman RL,Adler AI,Stratton IM,Matthews DR,Holman RR

更新日期：2004-01-01 00:00:00

abstract：:OBJECTIVE We examine barriers to receiving recommended eye care among people aged ≥40 years with diagnosed diabetes. RESEARCH DESIGN AND METHODS We analyzed 2006-2010 Behavioral Risk Factor Surveillance System data from 22 states (n = 27,699). Respondents who had not sought eye care in the preceding 12 months were ask...

journal_title：Diabetes care

authors： Chou CF,Sherrod CE,Zhang X,Barker LE,Bullard KM,Crews JE,Saaddine JB

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To establish the statistical significance of observed variations over the last decade in the incidence of insulin-dependent diabetes mellitus (IDDM) in the 0- to 19-yr-old age-group and to determine whether incidence has increased in Canterbury, New Zealand. RESEARCH DESIGN AND METHODS:The Canterbury, New Z...

journal_title：Diabetes care

authors： Scott RS,Brown LJ,Darlow BA,Forbes LV,Moore MP

更新日期：1992-07-01 00:00:00

abstract：:A semiclosed loop, bedside insulin infusion system using a simple basal infusion algorithm consisting of a linear transition between two insulin delivery rates as blood glucose (BG) increases has been developed. A theoretical study using computer simulation has now been undertaken to examine the effect of BG sampling ...

journal_title：Diabetes care

authors： Furler SM,Kraegen EW,Smallwood RH,Chisholm DJ

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:To determine whether macronutrient intake differs by awareness of glycemic status among people with diabetes and prediabetes. RESEARCH DESIGN AND METHODS:We used 24-h dietary recall and other data from 3,725 nonpregnant adults with diabetes or prediabetes aged ≥20 years from the morning fasting sample of the...

journal_title：Diabetes care

authors： Bardenheier BH,Cogswell ME,Gregg EW,Williams DE,Zhang Z,Geiss LS

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To determine maternal parameters with the strongest influence on fetal growth in different periods of pregnancies complicated by an abnormal glucose tolerance test (GTT). RESEARCH DESIGN AND METHODS:Retrospective study of 368 women with gestational diabetes mellitus (GDM; > or = 2 abnormal GTT values, n = 28...

journal_title：Diabetes care

authors： Schaefer-Graf UM,Kjos SL,Kilavuz O,Plagemann A,Brauer M,Dudenhausen JW,Vetter K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To investigate the metabolic effects of metformin, as compared with placebo, in type 2 diabetic patients intensively treated with insulin. RESEARCH DESIGN AND METHODS:Metformin improves glycemic control in poorly controlled type 2 diabetic patients. Its effect in type 2 diabetic patients who are intensively ...

journal_title：Diabetes care

authors： Wulffelé MG,Kooy A,Lehert P,Bets D,Ogterop JC,Borger van der Burg B,Donker AJ,Stehouwer CD

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of flexible intensive insulin therapy (FIIT) and an automated bolus calculator (ABC) in a Danish type 1 diabetes population treated with multiple daily injections. Furthermore, to test the feasibility of teaching FIIT in a 3-h structured course. RESEARCH DESIGN AND METHODS:The Bolus...

journal_title：Diabetes care

authors： Schmidt S,Meldgaard M,Serifovski N,Storm C,Christensen TM,Gade-Rasmussen B,Nørgaard K

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To determine if baseline subgroups in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial can be identified for whom intensive compared with standard glycemia treatment had different effects on all-cause mortality. RESEARCH DESIGN AND METHODS:Exploratory post hoc intention-to-treat compariso...

journal_title：Diabetes care

authors： Calles-Escandón J,Lovato LC,Simons-Morton DG,Kendall DM,Pop-Busui R,Cohen RM,Bonds DE,Fonseca VA,Ismail-Beigi F,Banerji MA,Failor A,Hamilton B

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a high-protein (HP) diet compared with a low-protein (LP) diet on weight loss, resting energy expenditure (REE), and the thermic effect of food (TEF) in subjects with type 2 diabetes during moderate energy restriction. RESEARCH DESIGN AND METHODS:In this study, 26 obese subjects wi...

journal_title：Diabetes care

authors： Luscombe ND,Clifton PM,Noakes M,Parker B,Wittert G

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To compare the weight losses of black and white patients with NIDDM treated in a year-long behavioral weight loss program. RESEARCH DESIGN AND METHODS:Subjects were randomly assigned to a behavioral program that either used a low-calorie diet throughout or included two 12-week periods of a very-low calorie d...

journal_title：Diabetes care

authors： Wing RR,Anglin K

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To quantify the incremental survival benefit of the pancreas allograft in simultaneous pancreas-kidney (SPK) transplant recipients. RESEARCH DESIGN AND METHODS:Data from the national transplant database from 2000 to 2007 were analyzed. SPK recipients who had functioning allografts to 1-year post transplant (...

journal_title：Diabetes care

authors： Salvalaggio PR,Dzebisashvili N,Pinsky B,Schnitzler MA,Burroughs TE,Graff R,Axelrod DA,Brennan DC,Lentine KL

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To describe the impact of abdominal obesity and hepatic insulin resistance on phase-specific glycemic responses in older women. RESEARCH DESIGN AND METHODS:We studied 23 healthy older women (60-88 years old). Abdominal obesity was defined by an abdominal circumference > or =95 cm. Plasma glucose and insulin ...

journal_title：Diabetes care

authors： DiPietro L,Dziura J,Yeckel CW

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Despite being a safe, effective therapy for lowering cardiovascular risk, only 20% of diabetic patients were using aspirin in the early 1990s. This study examines current physician practices and the use of aspirin therapy by individuals with diabetes. RESEARCH DESIGN AND METHODS:A random sample of diabetic p...

journal_title：Diabetes care

authors： Krein SL,Vijan S,Pogach LM,Hogan MM,Kerr EA

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:Gestational diabetes mellitus (GDM) is an increasingly prevalent risk factor for the development of type 2 diabetes in the mother and is responsible for morbidity in the child. To better identify women at risk of developing GDM we examined sociodemographic correlates and changes in the prevalence of GDM among...

journal_title：Diabetes care

authors： Anna V,van der Ploeg HP,Cheung NW,Huxley RR,Bauman AE

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:The objectives of this study were to compare early predictive marker of the metabolic syndrome with proopiomelanocortin (POMC) methylation status and to determine the association among birth weight, ponderal index, and cord blood methylation status. RESEARCH DESIGN AND METHODS:We collected pregnancy outcome ...

journal_title：Diabetes care

authors： Yoo JY,Lee S,Lee HA,Park H,Park YJ,Ha EH,Kim YJ

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Improved appetite control, possibly mediated by exaggerated gut peptide responses to eating, may contribute to weight loss after Roux-en-Y gastric bypass (RYGB). This study compared brain responses to food ingestion between post-RYGB (RYGB), normal weight (NW), and obese (Ob) unoperated subjects and explored ...

journal_title：Diabetes care

authors： Hunt KF,Dunn JT,le Roux CW,Reed LJ,Marsden PK,Patel AG,Amiel SA

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To investigate whether the risk for autoimmune diabetes in adults differs between socioeconomic groups and to compare such risk with that for type 2 diabetes. RESEARCH DESIGN AND METHODS:The inhabitants of the Norwegian county of Nord-Trøndelag were investigated by questionnaires and clinical examinations on...

journal_title：Diabetes care

authors： Olsson L,Ahlbom A,Grill V,Midthjell K,Carlsson S

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Because quantifying glycans with complex structures is technically challenging, little is known about the association of glycosylation profiles with the renal prognosis in diabetic kidney disease (DKD). RESEARCH DESIGN AND METHODS:In 675 patients with type 2 diabetes, we assessed the baseline urinary glycan ...

journal_title：Diabetes care

authors： Mise K,Imamura M,Yamaguchi S,Teshigawara S,Tone A,Uchida HA,Eguchi J,Nakatsuka A,Ogawa D,Yoshida M,Yamada M,Shikata K,Wada J

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To investigate whether self-rated health profiles compiled using the EuroQol group's visual analog scale (EQ VAS) are independent predictors of vascular events and major complications in people with type 2 diabetes after controlling for standard clinical risk factors. RESEARCH DESIGN AND METHODS:The study is...

journal_title：Diabetes care

authors： Hayes AJ,Clarke PM,Glasziou PG,Simes RJ,Drury PL,Keech AC

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine whether the use of meal bolus alarms would result in fewer missed meal boluses per week in youth with type 1 diabetes using continuous subcutaneous insulin infusion (CSII) therapy. RESEARCH DESIGN AND METHODS:This was a randomized trial of 48 youth using CSII, who were ...

journal_title：Diabetes care

authors： Chase HP,Horner B,McFann K,Yetzer H,Gaston J,Banion C,Fiallo-Scharer R,Slover R,Klingensmith G

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:Maturity-onset diabetes of the young (MODY) due to variants in HNF1A is the most common type of monogenic diabetes. Frequent misdiagnosis results in missed opportunity to use sulfonylureas as first-line treatment. A nongenetic biomarker could improve selection of subjects for genetic testing and increase diag...

journal_title：Diabetes care

authors： Juszczak A,Pavić T,Vučković F,Bennett AJ,Shah N,Pape Medvidović E,Groves CJ,Šekerija M,Chandler K,Burrows C,Rojnić Putarek N,Vučić Lovrenčić M,Ćuća Knežević J,James TJ,Gloyn AL,Lauc G,McCarthy MI,Owen KR,Gornik O

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Several methods have been proposed to evaluate insulin sensitivity from the data obtained from the oral glucose tolerance test (OGTT). However, the validity of these indices has not been rigorously evaluated by comparing them with the direct measurement of insulin sensitivity obtained with the euglycemic insu...

journal_title：Diabetes care

authors： Matsuda M,DeFronzo RA

更新日期：1999-09-01 00:00:00

abstract：:Diabetes is more common in older adults, has a high prevalence in long-term care (LTC) facilities, and is associated with significant disease burden and higher cost. The heterogeneity of this population with regard to comorbidities and overall health status is critical to establishing personalized goals and treatments...

journal_title：Diabetes care

authors： Munshi MN,Florez H,Huang ES,Kalyani RR,Mupanomunda M,Pandya N,Swift CS,Taveira TH,Haas LB

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:Little is known about the psychosocial challenges of adults living with type 1 diabetes or its impact on partner relationships. This qualitative study was undertaken to gain better understanding of these issues. RESEARCH DESIGN AND METHODS:Four focus groups were held, two with adult type 1 diabetic patients ...

journal_title：Diabetes care

authors： Trief PM,Sandberg JG,Dimmock JA,Forken PJ,Weinstock RS

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:In a few previous studies, cardiovascular disease (CVD) risk factors (RFs) have been shown to predict diabetes. Our objective was to determine whether the presence of CVD RFs predict the eventual development of diabetes after controlling for known RFs, such as directly measured insulin resistance and obesity....

journal_title：Diabetes care

authors： D'Agostino RB Jr,Hamman RF,Karter AJ,Mykkanen L,Wagenknecht LE,Haffner SM,Insulin Resistance Atherosclerosis Study Investigators.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Global usage of bariatric surgery has been dictated for the past quarter century by National Institutes of Health recommendations restricting these operations to individuals with a BMI ≥35 kg/m(2). Strong evidence now demonstrates that bariatric procedures markedly improve or cause remission of type 2 diabete...

journal_title：Diabetes care

authors： Cummings DE,Cohen RV

更新日期：2016-06-01 00:00:00