Incremental value of the pancreas allograft to the survival of simultaneous pancreas-kidney transplant recipients.

abstract：OBJECTIVE:To investigate the effect of treatment with the glucagon-like peptide 1 receptor agonist exenatide on weight loss and metabolic parameters in obese nondiabetic women. RESEARCH DESIGN AND METHODS:Forty-one obese women (aged 48 ± 11 years and BMI 33.1 ± 4.1 kg/m(2)) participated in a 35-week randomized, double...

journal_title：Diabetes care

authors： Dushay J,Gao C,Gopalakrishnan GS,Crawley M,Mitten EK,Wilker E,Mullington J,Maratos-Flier E

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Age at onset of type 1 diabetes influences the risk of microvascular complications. However, the long-term risk of proliferative retinopathy within the wide spectrum of age at onset of type 1 diabetes is less well known. RESEARCH DESIGN AND METHODS:A sample of 1,117 consecutively recruited patients was drawn...

journal_title：Diabetes care

authors： Hietala K,Harjutsalo V,Forsblom C,Summanen P,Groop PH,FinnDiane Study Group.

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Serine-threonine kinase STK11 catalyzes the AMP-activated protein kinase complex. We tested the hypothesis that a gene variant in STK11 contributes to variation in insulin sensitivity and metformin efficacy. RESEARCH DESIGN AND METHODS:We studied the effects of a single nucleotide polymorphism (SNP) (rs81116...

journal_title：Diabetes care

authors： López-Bermejo A,Díaz M,Morán E,de Zegher F,Ibáñez L

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of type 2 diabetes and impaired fasting glycemia (IFG) in a tribal population of Bangladesh. RESEARCH DESIGN AND METHODS:A cluster sampling of 1,287 tribal subjects of age > or =20 years was investigated. They live in a hilly area of Khagrachari in the far northeast of Bangladesh....

journal_title：Diabetes care

authors： Abu Sayeed M,Mahtab H,Akter Khanam P,Abul Ahsan K,Banu A,Rashid AN,Azad Khan AK

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Dietary protein is an important modulator of glucose metabolism. However, studies regarding the association between dietary protein intake and gestational diabetes mellitus (GDM) risk are sparse. This study was to examine the association. RESEARCH DESIGN AND METHODS:Our study included 21,457 singleton pregna...

journal_title：Diabetes care

authors： Bao W,Bowers K,Tobias DK,Hu FB,Zhang C

更新日期：2013-07-01 00:00:00

abstract：:Limited weight loss following jejunoileal bypass in 24 diabetic persons who were still distinctly overweight five to ten months after a mean weight decrease of 78 lbs. was accompanied by a return of normal fasting glucose and insulin levels, normal insulin responses, and a decrease in glucose intolerance. The glucose ...

journal_title：Diabetes care

authors： Ahmad U,Danowski TS,Nolan S,Stephan T,Sunder JH,Bahl VK

更新日期：1978-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of a moderate dose of fish oil on glycemic control and in vivo insulin action in type 2 diabetic men with elevated plasma triacylglycerols and to determine the effect of the same treatment on gene expression of GLUT4, lipoprotein lipase (LPL), and hormone-sensitive lipase (HSL) in the a...

journal_title：Diabetes care

authors： Luo J,Rizkalla SW,Vidal H,Oppert JM,Colas C,Boussairi A,Guerre-Millo M,Chapuis AS,Chevalier A,Durand G,Slama G

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare an in vivo test of whole-body glycolysis, the deuterated-glucose disposal test (2H-GDT), with insulin sensitivity measured by the euglycemic-hyperinsulinemic glucose clamp and the steady-state plasma glucose (SSPG) test. RESEARCH DESIGN AND METHODS:The 2H-GDT consists...

journal_title：Diabetes care

authors： Beysen C,Murphy EJ,McLaughlin T,Riiff T,Lamendola C,Turner HC,Awada M,Turner SM,Reaven G,Hellerstein MK

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:In type 1 diabetes (T1D), the course of microalbuminuria is unpredictable and timing of glomerular filtration rate (GFR) loss is uncertain. Thus, there is a need to identify the risk factors associated with the development of more advanced stages of kidney disease through large, long-term systematic analysis....

journal_title：Diabetes care

authors： Perkins BA,Bebu I,de Boer IH,Molitch M,Tamborlane W,Lorenzi G,Herman W,White NH,Pop-Busui R,Paterson AD,Orchard T,Cowie C,Lachin JM,Diabetes Control and Complications Trial (DCCT)\/Epidemiology of Diabetes Interventions and Com

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:This trial compared the efficacy and safety of the first oral glucagon-like peptide 1 (GLP-1) receptor agonist, oral semaglutide, as monotherapy with placebo in patients with type 2 diabetes managed by diet and exercise alone. Two estimands addressed two efficacy-related questions: a treatment policy estimand...

journal_title：Diabetes care

authors： Aroda VR,Rosenstock J,Terauchi Y,Altuntas Y,Lalic NM,Morales Villegas EC,Jeppesen OK,Christiansen E,Hertz CL,Haluzík M,PIONEER 1 Investigators.

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Many studies have shown that diabetes increases the risk of cardiovascular disease (CVD) in women to a greater extent than in men. One explanation could be that diabetes has more adverse effects on CVD risk factors in women than in men. We compared diabetes-associated differences in CVD risk factors in men an...

journal_title：Diabetes care

authors： Howard BV,Cowan LD,Go O,Welty TK,Robbins DC,Lee ET

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:Women exhibit exaggerated renal hemodynamic responses to hyperglycemia, which may promote kidney disease progression. Our aim was to determine if increased nitric oxide generation by l-arginine infusion would reverse this deleterious response to clamped hyperglycemia in women with type 1 diabetes mellitus. R...

journal_title：Diabetes care

authors： Cherney DZ,Scholey JW,Sochett EB

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine patient-reported outcomes in a controlled trial of a multifaceted provider-level intervention to improve quality of care for rural patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:We conducted a before/after intervention study with concurrent controls in two rur...

journal_title：Diabetes care

authors： Maddigan SL,Majumdar SR,Guirguis LM,Lewanczuk RZ,Lee TK,Toth EL,Johnson JA

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:Molecular defects of hepatocyte nuclear factor 1B (HNF1B) are associated with a multiorgan disease, including diabetes (maturity-onset diabetes of the young 5) and kidney abnormalities. The HNF1B syndrome is related to HNF1B mutations or to a 17q12 deletion spanning 15 genes, including HNF1B. Here, we describ...

journal_title：Diabetes care

authors： Dubois-Laforgue D,Cornu E,Saint-Martin C,Coste J,Bellanné-Chantelot C,Timsit J,Monogenic Diabetes Study Group of the Société Francophone du Diabète.

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Assessing updated incidence of type 1 diabetes in 0- to 14-year-old children in Liguria, a Northwest region of Italy. RESEARCH DESIGN AND METHODS:Incident cases were recorded prospectively from 1989 to 1998. Incidence rates (IRs) were standardized to the 1999 world population using the direct method. The ind...

journal_title：Diabetes care

authors： Cotellessa M,Barbieri P,Mazzella M,Bonassi S,Minicucci L,Lorini R

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To evaluate and validate appropriate premeal insulin dose reductions for postprandial exercises of different intensities and durations to minimize the risk of exercise-induced hypoglycemia in type 1 diabetic subjects. RESEARCH DESIGN AND METHODS:Eight male type 1 diabetic patients on a basal-bolus insulin re...

journal_title：Diabetes care

authors： Rabasa-Lhoret R,Bourque J,Ducros F,Chiasson JL

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:To assess the dose-ranging efficacy and safety of LX4211, a dual inhibitor of sodium-glucose cotransporter (SGLT) 1 and SGLT2, in type 2 diabetes. RESEARCH DESIGN AND METHODS:Type 2 diabetic patients inadequately controlled on metformin were randomly assigned to 75 mg once daily, 200 mg once daily, 200 mg tw...

journal_title：Diabetes care

authors： Rosenstock J,Cefalu WT,Lapuerta P,Zambrowicz B,Ogbaa I,Banks P,Sands A

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:Recent studies show the importance of controlling blood glucose variability in relationship to both reducing hypoglycemia and attenuating the risk for cardiovascular and behavioral complications due to hyperglycemia. It is therefore important to design variability measures that are equally predictive of low a...

journal_title：Diabetes care

authors： Kovatchev BP,Otto E,Cox D,Gonder-Frederick L,Clarke W

更新日期：2006-11-01 00:00:00

abstract：:OBJECTIVE Using the clamp technique, youths with a clinical diagnosis of type 2 diabetes (CDx-type 2 diabetes) and positive pancreatic autoantibodies (Ab(+)) were shown to have severe impairment in insulin secretion and less insulin resistance than their peers with negative antibodies (Ab(-)). In this study, we invest...

journal_title：Diabetes care

authors： Tfayli H,Bacha F,Gungor N,Arslanian S

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:The goal was to assess the 1-year efficacy and safety of the addition of pioglitazone or metformin to existing sulfonylurea (SU) therapy in patients with inadequately controlled type 2 diabetes. RESEARCH DESIGN AND METHODS:In this multicenter, double-blind study, patients were randomized to receive either pi...

journal_title：Diabetes care

authors： Hanefeld M,Brunetti P,Schernthaner GH,Matthews DR,Charbonnel BH,QUARTET Study Group.

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between the use of ACE inhibitors and hospital admission for severe hypoglycemia and to explore the effects of potential confounding variables on this relationship. RESEARCH DESIGN AND METHODS:The association between the use of ACE inhibitors and the incidence of hypoglycemia is c...

journal_title：Diabetes care

authors： Morris AD,Boyle DI,McMahon AD,Pearce H,Evans JM,Newton RW,Jung RT,MacDonald TM

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:Physical activity is integral to the management of type 2 diabetes. Unfortunately, the majority of adults with type 2 diabetes do not regularly engage in physical activity. The purpose of this study was to assess physical activity behavior and its correlates (i.e., physical activity knowledge, barriers, and p...

journal_title：Diabetes care

authors： Hays LM,Clark DO

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:To assess the impact of hyperglycemia in different age-groups of patients with acute myocardial infarction (AMI). RESEARCH DESIGN AND METHODS:A total of 2,027 patients with AMI were categorized into one of five age-groups: <50 years (n = 301), ≥50 and <60 (n = 477), ≥60 and <70 (n = 545), ≥70 and <80 (n = 49...

journal_title：Diabetes care

authors： Nicolau JC,Serrano CV Jr,Giraldez RR,Baracioli LM,Moreira HG,Lima F,Franken M,Kalil R,Ramires JA,Giugliano RP

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To evaluate safety and efficacy of DiaPep277 in preserving β-cell function in type 1 diabetic patients. RESEARCH DESIGN AND METHODS:DIA-AID 1 is a multinational, phase 3, balanced-randomized, double-blind, placebo-controlled, parallel-group clinical study. Newly diagnosed patients (N = 457, aged 16-45 years)...

journal_title：Diabetes care

authors： Raz I,Ziegler AG,Linn T,Schernthaner G,Bonnici F,Distiller LA,Giordano C,Giorgino F,de Vries L,Mauricio D,Procházka V,Wainstein J,Elias D,Avron A,Tamir M,Eren R,Peled D,Dagan S,Cohen IR,Pozzilli P,DIA-AID 1 Writin

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Little evidence exists regarding long-term diet quality and the risk of type 2 diabetes among Asian populations, who have undergone a nutrition transition and a diabetes epidemic. RESEARCH DESIGN AND METHODS:A total of 117,919 Chinese men and women, 40-74 years old, free of diabetes, cardiovascular disease, ...

journal_title：Diabetes care

authors： Yu D,Zheng W,Cai H,Xiang YB,Li H,Gao YT,Shu XO

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To determine whether diabetes risk is influenced by which parent (a parental history of diabetes is a well-documented risk factor for NIDDM) is reported to have diabetes. RESEARCH DESIGN AND METHODS:We compared the prevalence of NIDDM and IGT for 4914 subjects according to their parental history of diabetes ...

journal_title：Diabetes care

authors： Mitchell BD,Valdez R,Hazuda HP,Haffner SM,Monterrosa A,Stern MP

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:The levels of the surrogate markers of cholesterol absorption (cholestanol and plant sterols) and synthesis (cholesterol precursors) in serum have suggested that in adult type 1 diabetes, cholesterol absorption is high and synthesis is low compared with type 2 diabetic or control subjects. Accordingly, these ...

journal_title：Diabetes care

authors： Järvisalo M,Raitakari O,Gylling H,Miettinen TA

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:Wound healing is known to require a well-organized balance of numerous factors, e.g., cytokines, matrix metalloproteinases (MMPs), and their inhibitors, as well as direct cell-cell communication (connexins). Disruption of this balance may lead to the formation of chronic wounds such as diabetic foot ulcers. T...

journal_title：Diabetes care

authors： Brandner JM,Zacheja S,Houdek P,Moll I,Lobmann R

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the association between foot ulcers (DFU) and lower-extremity amputation (LEA) and chronic kidney disease (CKD) in patients with diabetes. RESARCH DESIGN AND METHODS: This was a retrospective cohort study of individuals enrolled between 2002 and 2006 who were aged >...

journal_title：Diabetes care

authors： Margolis DJ,Hofstad O,Feldman HI

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To compare the duration of healing of foot ulcers with osteomyelitis in diabetic patients treated by medical treatment versus medical treatment associated with conservative orthopedic surgery. RESEARCH DESIGN AND METHODS:We entered into the study 67 diabetic patients who had a foot ulcer with osteomyelitis w...

journal_title：Diabetes care

authors： Ha Van G,Siney H,Danan JP,Sachon C,Grimaldi A

更新日期：1996-11-01 00:00:00