Age at onset and the risk of proliferative retinopathy in type 1 diabetes.

Abstract:

OBJECTIVE:Age at onset of type 1 diabetes influences the risk of microvascular complications. However, the long-term risk of proliferative retinopathy within the wide spectrum of age at onset of type 1 diabetes is less well known. RESEARCH DESIGN AND METHODS:A sample of 1,117 consecutively recruited patients was drawn from the FinnDiane Study population (4,800 patients). Type 1 diabetes was defined as age at onset or=15 years (1.82 [1.40-2.36], P < 0.001). CONCLUSIONS:Age at onset significantly modifies the long-term risk of proliferative retinopathy. The highest risk is in age-at-onset group 5-14 years, whereas the lowest risk is in age-at-onset group 15-40 years.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Hietala K,Harjutsalo V,Forsblom C,Summanen P,Groop PH,FinnDiane Study Group.

doi

10.2337/dc09-2278

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

1315-9

issue

6

eissn

0149-5992

issn

1935-5548

pii

dc09-2278

journal_volume

33

pub_type

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