Treatment of osteomyelitis in the diabetic foot. Contribution of conservative surgery.

Abstract:

OBJECTIVE:To compare the duration of healing of foot ulcers with osteomyelitis in diabetic patients treated by medical treatment versus medical treatment associated with conservative orthopedic surgery. RESEARCH DESIGN AND METHODS:We entered into the study 67 diabetic patients who had a foot ulcer with osteomyelitis without ischemia requiring a peripheral arterial reconstruction. Thirty-two diabetic patients were included in a first historic group from 1986 to 1993, treated by antibiotic therapy, offloading, and wound care. Thirty-two patients were included from September 1993 to March 1995, treated by the same medical treatment and conservative orthopedic surgery. RESULTS:The healing rate was 57% in the group treated by the medical treatment alone versus 78% in the surgical group (P < 0.008). The duration of healing was 462 +/- 98 days versus 181 +/- 30 days (P < 0.008). CONCLUSIONS:Conservative surgery contributes to an increase in the healing rate of foot ulcers with osteomyelitis compared with a medical treatment alone.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Ha Van G,Siney H,Danan JP,Sachon C,Grimaldi A

doi

10.2337/diacare.19.11.1257

subject

Has Abstract

pub_date

1996-11-01 00:00:00

pages

1257-60

issue

11

eissn

0149-5992

issn

1935-5548

journal_volume

19

pub_type

临床试验,杂志文章
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    abstract:OBJECTIVE:To review the published literature and perform a meta-analysis summarizing the evidence in support of an inverse association between type 1 diabetes and the atopic disorders: asthma, eczema, and allergic rhinitis in children. RESEARCH DESIGN AND METHODS:MEDLINE, Web of Science, and PubMed were searched to id...

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    authors: Cardwell CR,Shields MD,Carson DJ,Patterson CC

    更新日期:2003-09-01 00:00:00

  • Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity.

    abstract::Type 1 diabetes (T1D) and celiac disease (CeD) cluster in families and can occur in the same individual. Genetic loci have been associated with susceptibility to both diseases. Our aim was to explore the genetic differences between individuals developing both these diseases (double autoimmunity) versus those with only...

    journal_title:Diabetes care

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    doi:10.2337/dcs15-2007

    authors: Gutierrez-Achury J,Romanos J,Bakker SF,Kumar V,de Haas EC,Trynka G,Ricaño-Ponce I,Steck A,Type 1 Diabetes Genetics Consortium.,Chen WM,Onengut-Gumuscu S,Simsek S,Diabeter.,Rewers M,Mulder CJ,Liu E,Rich SS,Wijmenga C

    更新日期:2015-10-01 00:00:00

  • Detection of symptoms by adolescents and young adults with type 1 diabetes during experimental induction of mild hypoglycemia: role of hormonal and psychological variables.

    abstract:OBJECTIVE:To identify hormonal, psychological, and demographic predictors of symptom detection and accuracy of blood glucose estimation during mild hypoglycemia in adolescents and young adults with type 1 diabetes. RESEARCH DESIGN AND METHODS:During an insulin-glucose clamp study, 53 adolescents and 19 young adults es...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.25.5.852

    authors: Ryan CM,Dulay D,Suprasongsin C,Becker DJ

    更新日期:2002-05-01 00:00:00

  • Diabetes complications in youth: qualitative analysis of parents' perspectives of family learning and knowledge.

    abstract:OBJECTIVE:Youth with type 1 diabetes face long-term risks of health complications of the disease. Little is known about patients' and parents' knowledge, acquisition of information, and family communication regarding these complications. This paper reports qualitative analyses of parental focus-group discussions of thi...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc07-2349

    authors: Buckloh LM,Lochrie AS,Antal H,Milkes A,Canas JA,Hutchinson S,Wysocki T

    更新日期:2008-08-01 00:00:00

  • Relationship of retinal vascular caliber with diabetes and retinopathy: the Multi-Ethnic Study of Atherosclerosis (MESA).

    abstract:OBJECTIVE:To examine the relationship of retinal vascular caliber with diabetes, glycemia, and diabetic retinopathy. RESEARCH DESIGN AND METHODS:Population-based study using data from the Multi-Ethnic Study of Atherosclerosis (MESA), comprising 5,976 individuals (whites, blacks, Hispanics, and Chinese) residing in six...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc07-1528

    authors: Nguyen TT,Wang JJ,Sharrett AR,Islam FM,Klein R,Klein BE,Cotch MF,Wong TY

    更新日期:2008-03-01 00:00:00

  • Does glycemic control offer similar benefits among patients with diabetes in different regions of the world? Results from the ADVANCE trial.

    abstract:OBJECTIVE:Participants in ADVANCE were drawn from many countries. We examined whether the effects of intensive glycemic control on major outcomes in ADVANCE differ between participants from Asia, established market economies (EMEs), and eastern Europe. RESEARCH DESIGN AND METHODS:ADVANCE was a clinical trial of 11,140...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc11-0755

    authors: Woodward M,Patel A,Zoungas S,Liu L,Pan C,Poulter N,Januszewicz A,Tandon N,Joshi P,Heller S,Neal B,Chalmers J

    更新日期:2011-12-01 00:00:00

  • Importance of timing of preprandial subcutaneous insulin administration in the management of diabetes mellitus.

    abstract::Since little is known regarding the appropriate time for preprandial insulin administration, we compared the effects of 30-min subcutaneous insulin infusions started 60 min, 30 min, and immediately before meal ingestion on postprandial plasma glucose and insulin profiles in eight subjects with insulin-dependent diabet...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.6.4.374

    authors: Dimitriadis GD,Gerich JE

    更新日期:1983-07-01 00:00:00

  • Cellular ions in NIDDM: relation of calcium to hyperglycemia and cardiac mass.

    abstract:OBJECTIVE:To investigate the role of hyperglycemia in mediating the clinical association of NIDDM with hypertension and left ventricular dysfunction and hypertrophy. RESEARCH DESIGN AND METHODS:Since hyperglycemia elevates cytosolic free calcium (Cai) both in myocardial and vascular smooth muscle cells, we utilized nu...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.19.12.1393

    authors: Barbagallo M,Gupta RK,Resnick LM

    更新日期:1996-12-01 00:00:00

  • Longitudinal study of carbohydrate metabolism in healthy obese pregnant women.

    abstract:OBJECTIVE:To longitudinally characterize changes in insulin sensitivity in obese women during and after pregnancy. RESEARCH DESIGN AND METHODS:Six glucose-tolerant obese women underwent a 4-h euglycemic-hyperinsulinemic (500-600 pmol/l) clamping during the second (22.5 +/- 2 weeks [mean +/- SD]) and third trimester (3...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.9.1470

    authors: Sivan E,Chen X,Homko CJ,Reece EA,Boden G

    更新日期:1997-09-01 00:00:00

  • Decreased skin wrinkling in diabetes mellitus.

    abstract::Skin wrinkling, which may be dependent on peripheral autonomic innervation, was assessed in 100 normal and 42 diabetic subjects using a temperature-controlled water bath with immersion of the hands for 30 min. Markedly decreased skin wrinkling was observed in diabetic subjects and in manual workers, but did not correl...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.7.3.224

    authors: Clark CV,Pentland B,Ewing DJ,Clarke BF

    更新日期:1984-05-01 00:00:00

  • Dual hormonal replacement with insulin and recombinant human insulin-like growth factor I in IDDM. Effects on glycemic control, IGF-I levels, and safety profile.

    abstract:OBJECTIVE:To examine if dual replacement with insulin and rhIGF-I, recombinant human insulin-like growth factor I (rhIGF-I) may be safe and result in improved metabolic control and reduced insulin usage. RESEARCH DESIGN AND METHODS:Forty-three patients with IDDM were randomized to receive a daily injection of rhIGF-I ...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.2337/diacare.20.3.374

    authors: Quattrin T,Thrailkill K,Baker L,Litton J,Dwigun K,Rearson M,Poppenheimer M,Giltinan D,Gesundheit N,Martha P Jr

    更新日期:1997-03-01 00:00:00

  • Diet-quality scores and the risk of type 2 diabetes in men.

    abstract:OBJECTIVE:To 1) compare associations of diet-quality scores, which were inversely associated with cardiovascular disease, with incident type 2 diabetes and 2) test for differences in absolute-risk reduction across various strata. RESEARCH DESIGN AND METHODS:Men from the Health Professionals Follow-Up Study, who were i...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-2352

    authors: de Koning L,Chiuve SE,Fung TT,Willett WC,Rimm EB,Hu FB

    更新日期:2011-05-01 00:00:00

  • Pancreas transplantation improves vascular disease in patients with type 1 diabetes.

    abstract:OBJECTIVE:Pancreas transplantation (PTX) normalizes glucose and improves microvascular complications, but its impact on macrovascular disease is still debated. RESEARCH DESIGN AND METHODS:Carotid intima-media thickness (IMT), shown to correlate with cardiovascular disease (CVD) risk and events, was determined prospect...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.27.7.1706

    authors: Larsen JL,Colling CW,Ratanasuwan T,Burkman TW,Lynch TG,Erickson JM,Lyden ER,Lane JT,Mack-Shipman LR

    更新日期:2004-07-01 00:00:00

  • Clinical usefulness of different lipid measures for prediction of coronary heart disease in type 2 diabetes: a report from the Swedish National Diabetes Register.

    abstract:OBJECTIVE:We assessed the association between different blood lipid measures and risk of fatal/nonfatal coronary heart disease (CHD). RESEARCH DESIGN AND METHODS:We conducted an observational study of patients with type 2 diabetes from the Swedish National Diabetes Register. Baseline LDL cholesterol, non-HDL cholester...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc11-0209

    authors: Eliasson B,Cederholm J,Eeg-Olofsson K,Svensson AM,Zethelius B,Gudbjörnsdottir S,National Diabetes Register.

    更新日期:2011-09-01 00:00:00

  • Optimal insulin delivery for the pregnant diabetic patient.

    abstract::It is now possible to virtually normalize ambient blood glucose levels in insulin-dependent diabetic women during pregnancy. Successful programs have been developed that utilize home blood glucose monitoring, physiologic delivery of insulin, and quantitation of caloric intake carefully matched to insulin dosage. The r...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:

    authors: Jovanovic L,Peterson CM

    更新日期:1982-05-01 00:00:00

  • Subclinical and clinical eating disorders in IDDM negatively affect metabolic control.

    abstract:OBJECTIVE:To characterize the relationship of subclinical and clinical eating disorders to HbA1c values in women with IDDM. RESEARCH DESIGN AND METHODS:Ninety women with IDDM (18-46 years of age) were recruited from diabetes clinics throughout Connecticut and Massachusetts. Subjects were categorized into one of three ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.2.182

    authors: Affenito SG,Backstrand JR,Welch GW,Lammi-Keefe CJ,Rodriguez NR,Adams CH

    更新日期:1997-02-01 00:00:00

  • Eating fish and risk of type 2 diabetes: A population-based, prospective follow-up study.

    abstract:OBJECTIVE:To investigate the relation between total fish, type of fish (lean and fatty), and eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) intake and risk of type 2 diabetes in a population-based cohort. RESEARCH DESIGN AND METHODS:The analysis included 4,472 Dutch participants aged >or=55 years without d...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-1042

    authors: van Woudenbergh GJ,van Ballegooijen AJ,Kuijsten A,Sijbrands EJ,van Rooij FJ,Geleijnse JM,Hofman A,Witteman JC,Feskens EJ

    更新日期:2009-11-01 00:00:00

  • Trends in health care expenditure in U.S. adults with diabetes: 2002-2011.

    abstract:OBJECTIVE:Direct medical cost of diabetes in the U.S. has been estimated to be 2.3 times higher relative to individuals without diabetes. This study examines trends in health care expenditures by expenditure category in U.S. adults with diabetes between 2002 and 2011. RESEARCH DESIGN AND METHODS:We analyzed 10 years o...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc15-0369

    authors: Ozieh MN,Bishu KG,Dismuke CE,Egede LE

    更新日期:2015-10-01 00:00:00

  • Association between renal failure and foot ulcer or lower-extremity amputation in patients with diabetes.

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    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/dc07-2244

    authors: Margolis DJ,Hofstad O,Feldman HI

    更新日期:2008-07-01 00:00:00

  • Prevalence and correlates of depressive symptoms among rural older African Americans, Native Americans, and whites with diabetes.

    abstract:OBJECTIVE:Depression is associated with morbidity, mortality, and decreased quality of life and is a well-established complication among people with diabetes. Little is known about the prevalence and correlates of depressive symptoms among older adults living in rural communities, particularly among ethnic minority gro...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.28.4.823

    authors: Bell RA,Smith SL,Arcury TA,Snively BM,Stafford JM,Quandt SA

    更新日期:2005-04-01 00:00:00

  • Predictors of Quality of Life and Other Patient-Reported Outcomes in the PANORAMA Multinational Study of People With Type 2 Diabetes.

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    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

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    authors: Bradley C,Eschwège E,de Pablos-Velasco P,Parhofer KG,Simon D,Vandenberghe H,Gönder-Frederick L

    更新日期:2018-02-01 00:00:00

  • Mortality and morbidity associated with body weight in people with IDDM. The WHO Multinational Study of Vascular Disease in Diabetes.

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    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/diacare.18.6.761

    authors: Chaturvedi N,Stevens LK,Fuller JH

    更新日期:1995-06-01 00:00:00

  • Use of tactile techniques for self-monitoring of blood glucose in visually impaired patients with diabetes mellitus.

    abstract::Twenty-eight patients with type I diabetes mellitus, legally blind as a result of proliferative retinopathy, were recruited into a program designed to teach and evaluate tactile methods for self-monitoring of blood glucose (SMBG). Vision ranged from "blind" to "able to read large print." Techniques with wipe-off strip...

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    pub_type: 杂志文章

    doi:10.2337/diacare.7.4.313

    authors: Prior JC,Alojado NC,Hunt JA,Begg IS

    更新日期:1984-07-01 00:00:00

  • Development of questionnaire to examine relationship of physical activity and diabetes in Pima Indians.

    abstract::There was a need to design a questionnaire that could accurately assess the activity patterns of Native Americans to evaluate the relationship between physical activity and diabetes. Such a questionnaire was developed and implemented into the data collection scheme of the prospective Pima Indian Study of Arizona. The ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.13.4.401

    authors: Kriska AM,Knowler WC,LaPorte RE,Drash AL,Wing RR,Blair SN,Bennett PH,Kuller LH

    更新日期:1990-04-01 00:00:00

  • Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S.

    abstract:OBJECTIVE:The International Diabetes Federation (IDF) has proposed a new definition of the metabolic syndrome that emphasizes central adiposity as determined by ethnic group-specific thresholds of waist circumference. The objective of this study was to estimate the prevalence of this syndrome using the IDF definition a...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.28.11.2745

    authors: Ford ES

    更新日期:2005-11-01 00:00:00

  • Initiating insulin as part of the Treating To Target in Type 2 Diabetes (4-T) trial: an interview study of patients' and health professionals' experiences.

    abstract:OBJECTIVE:To explore patients' and health professionals' experiences of initiating insulin as part of the Treating To Target in Type 2 Diabetes (4-T) randomized controlled trial. RESEARCH DESIGN AND METHODS:Interviews were conducted with 45 trial participants and 21 health professionals and thematically analyzed. RES...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc10-0494

    authors: Jenkins N,Hallowell N,Farmer AJ,Holman RR,Lawton J

    更新日期:2010-10-01 00:00:00

  • Translating lifestyle intervention to practice in obese patients with type 2 diabetes: Improving Control with Activity and Nutrition (ICAN) study.

    abstract:OBJECTIVE:To assess the efficacy of a lifestyle intervention program that can be readily translated into clinical practice for obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:The study consisted of a 12-month randomized controlled trial of 147 health plan members with type 2 diabetes and obesity (BMI ...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.27.7.1570

    authors: Wolf AM,Conaway MR,Crowther JQ,Hazen KY,L Nadler J,Oneida B,Bovbjerg VE,Improving Control with Activity and Nutrition (ICAN) Study.

    更新日期:2004-07-01 00:00:00

  • The epidemiology of diabetes in pregnant Native Canadians. A risk profile.

    abstract:OBJECTIVE:The purpose of this study was to determine the prevalence of diabetes in pregnancy (gestational diabetes mellitus [GDM] and NIDDM) and to identify risk factors in the development of GDM in a native population in northwestern Ontario, Canada. RESEARCH DESIGN AND METHODS:A retrospective analysis of 1,305 singl...

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    pub_type: 杂志文章

    doi:10.2337/diacare.20.9.1422

    authors: Harris SB,Caulfield LE,Sugamori ME,Whalen EA,Henning B

    更新日期:1997-09-01 00:00:00

  • Novel Protein Glycan-Derived Markers of Systemic Inflammation and C-Reactive Protein in Relation to Glycemia, Insulin Resistance, and Insulin Secretion.

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    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc16-1569

    authors: Lorenzo C,Festa A,Hanley AJ,Rewers MJ,Escalante A,Haffner SM

    更新日期:2017-03-01 00:00:00

  • Insulin-resistant diabetes with insulin receptor autoantibodies in a male patient without acanghosis nigricans.

    abstract::A 51-yr-old, nonobese, male patient presented with hyperglycemia and a recent 40-pound weight loss. Severe insulin resistance was documented in studies in which high amounts of insulin were infused using the Biostator GCIIS. Diabetic control was finally achieved with subcutaneous injections of 470 U of insulin per day...

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    doi:10.2337/diacare.2.3.275

    authors: Baldwin D Jr,Winston E,Hoshizaki RJ,Garland JT,Baldwin D Sr,Holcomb HH,Flier JS,Rubenstein A

    更新日期:1979-05-01 00:00:00