Abstract:
OBJECTIVE:Assessing updated incidence of type 1 diabetes in 0- to 14-year-old children in Liguria, a Northwest region of Italy. RESEARCH DESIGN AND METHODS:Incident cases were recorded prospectively from 1989 to 1998. Incidence rates (IRs) were standardized to the 1999 world population using the direct method. The independent effect of sex, age, residence, and calendar year was estimated with Poisson regression model. The degree of ascertainment was calculated in accordance to capture/recapture method. RESULTS:During 10 full calendar years, 219 new cases of type 1 diabetes in children were diagnosed in Liguria. The standardized IR over the 10-year period was 12.56 cases per 100,000 per year (95% CI 11.0-14.3). The sex-specific IR among men and women was 14.15 and 10.88, respectively. The age-specific IR was higher in the 10- to 14-year-old age-group (15.01/100,000) than in 0- to 4-year-old age-group (9.01/100,000) and in the 5- to 9-year-old age-group (13.03/100,000). CONCLUSIONS:The IR of type 1 diabetes in Liguria is among the highest in Southern Europe and approaches IRs of Northern European countries. In particular it is much higher than those reported in the surrounding Italian regions except for Sardinia. Therefore, the geographical distribution of type 1 diabetes does not seem to reflect the simple North-South gradient reported in several previous works.
journal_name
Diabetes Carejournal_title
Diabetes careauthors
Cotellessa M,Barbieri P,Mazzella M,Bonassi S,Minicucci L,Lorini Rdoi
10.2337/diacare.26.6.1786subject
Has Abstractpub_date
2003-06-01 00:00:00pages
1786-9issue
6eissn
0149-5992issn
1935-5548journal_volume
26pub_type
杂志文章相关文献
DIABETES CARE文献大全abstract:OBJECTIVE:No study has reported global disability burden estimates for individual diabetes-related lower-extremity complications (DRLECs). The Global Burden of Disease (GBD) study presents a robust opportunity to address this gap. RESEARCH DESIGN AND METHODS:GBD 2016 data, including prevalence and years lived with dis...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc19-1614
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:In patients with type 2 diabetes, microalbuminuria is associated with an increase in predominantly cardiovascular mortality. Considerable interindividual variability in the rate of progression of microalbuminuria exists. The prognostic significance of rate of progression of microalbuminuria with regard to car...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.24.12.2097
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVE:To review the published literature and perform a meta-analysis summarizing the evidence in support of an inverse association between type 1 diabetes and the atopic disorders: asthma, eczema, and allergic rhinitis in children. RESEARCH DESIGN AND METHODS:MEDLINE, Web of Science, and PubMed were searched to id...
journal_title:Diabetes care
pub_type: 杂志文章,meta分析
doi:10.2337/diacare.26.9.2568
更新日期:2003-09-01 00:00:00
abstract::OBJECTIVE--To determine and compare the abilities of various anthropometric measurements to predict the development of non-insulin-dependent diabetes mellitus (NIDDM) in Pima Indian men and women. RESEARCH DESIGN AND METHODS--A total of 290 male and 443 female Pima Indians were followed for up to 6 years for the devel...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.18.4.435
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:The present study was designed to assess the effect of magnesium plus zinc, vitamins C plus E, and a combination of these micronutrients on nephropathy indexes in type 2 diabetic patients. RESEARCH DESIGN AND METHODS:In a randomized, double-blind, placebo-controlled clinical trial, 69 type 2 diabetic patient...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/diacare.28.10.2458
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To examine by meta-analysis the relationship between cardiovascular autonomic neuropathy (CAN) and risk of mortality in individuals with diabetes. RESEARCH DESIGN AND METHODS:We searched Medline for English-language articles published from 1966 to 2001. Fifteen studies having a baseline assessment of cardiov...
journal_title:Diabetes care
pub_type: 杂志文章,meta分析
doi:10.2337/diacare.26.6.1895
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To evaluate whether homeostasis model assessment-estimated insulin resistance (HOMA-IR) is an independent predictor of cardiovascular disease (CVD) in type 2 diabetes. RESEARCH DESIGN AND METHODS:Conventional CVD risk factors (sex, age, smoking, plasma lipids, blood pressure, and metabolic control) and insul...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究
doi:10.2337/diacare.25.7.1135
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:Obesity and type 2 diabetes mellitus (T2DM) are associated with altered food-related neuronal functions. Besides weight loss, substantial improvement of glucose metabolism in patients with T2DM can be achieved by bariatric surgery. We aimed to target the neuronal and behavioral correlates of improved glycemic...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc16-0094
更新日期:2016-08-01 00:00:00
abstract::This study compares the utility of nonenzymatically glycosylated serum proteins (lys-GSP) to glycosylated hemoglobins (HbA1a-c) as control indices of glucose homeostasis in patients with IDDM. The diagnostic value of lys-GSP was also examined in patients with non-insulin-dependent diabetes mellitus, in subjects with i...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.7.6.548
更新日期:1984-11-01 00:00:00
abstract:OBJECTIVE:This study compared diabetes Treatment As Usual (TAU) with Pathways To Change (PTC), an intervention developed from the Transtheoretical Model of Change (TTM), to determine whether the PTC intervention would result in greater readiness to change, greater increases in self-care, and improved diabetes control. ...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.26.3.732
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:Long-term implications of childhood obesity and BMI change over the life course for risk of type 2 diabetes remain uncertain. The objective was to establish whether there are effects on adult glucose metabolism of 1) sensitive periods of BMI gain or 2) long duration of overweight and obesity. RESEARCH DESIGN...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc10-1482
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To characterize the insulin sensitivity of overweight and obese 5- to 10-year-old (Tanner stage 1-3) African-American children screened for participation in a diabetes prevention study and to identify the association of insulin sensitivity with obesity, hyperlipidemia, and hypertension. RESEARCH DESIGN AND M...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.24.8.1359
更新日期:2001-08-01 00:00:00
abstract::This review summarizes Session IV: Therapeutic Interventions of the Fourth International Gestational Diabetes Workshop and suggests intervention protocols based on the presentations at this meeting and the literature. The opinions of the six presenters and their interpretation of the review of the literature in their ...
journal_title:Diabetes care
pub_type: 杂志文章,评审
doi:
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVE:The impact of major affective disorders on the effectiveness of diabetes prevention programs at promoting health behaviors has not been established. We investigated whether depression modifies the effectiveness of two pragmatic diabetes prevention programs at promoting increased physical activity. RESEARCH D...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc19-0400
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:Our objective was to analyze the prevalence, incidence, and mortality of diabetes in a population of 280,539 inhabitants. RESEARCH DESIGN AND METHODS:The incidence, prevalence, and deaths from diabetes at all ages of a population have been prospectively followed in the county of Skaraborg, Sweden, since 1991...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.22.5.773
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:Left ventricular remodeling occurs immediately after MI, involving structural changes in noninfarcted segment. However, the residual left ventricular pump function in NIDDM patients after acute MI has not been clarified. The purpose of this study was to evaluate the difference in the process of left ventricul...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.15.11.1522
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVE:In patients with type 2 diabetes and cardiovascular diseases (CVDs), intensive treatment with insulin and/or sulfonylurea (SU) may be associated with excessive increased risk of hypoglycemic episodes. To evaluate the risk of critical arrhythmias related to glycemic variability, we carried out an observational...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc13-0600
更新日期:2014-02-01 00:00:00
abstract::High-density lipoprotein (HDL) cholesterol is known to be low in patients with diabetes mellitus. Low HDL levels are correlated with premature cardiovascular mortality in several major epidemiologic studies and many investigators believe increases in HDL cholesterol may reduce the risk of coronary heart disease. We ev...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.8.4.343
更新日期:1985-07-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of female sexual dysfunction (FSD) in diabetic and nondiabetic Jordanian women. RESEARCH DESIGN AND METHODS:Data were collected from 1,137 married women using the Arabic translation of the Female Sexual Function Index questionnaire. RESULTS:Prevalence of sexual dysfunction in diab...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc08-0081
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:We assessed whether type 2 diabetes is associated with renal cell carcinoma (RCC), independent of key potential confounders, in two large prospective cohorts with biennially updated covariate data. RESEARCH DESIGN AND METHODS:A total of 117,570 women from the Nurses' Health Study (NHS) and 48,866 men from th...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc17-2518
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to examine the associations between the severity of hepatic steatosis and dyslipidemia in type 2 diabetes, including circulating apolipoprotein B100 (apoB) concentrations and lipoprotein particle size and numbers. RESEARCH DESIGN AND METHODS:Computed tomography imaging was use...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc06-0455
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:To investigate whether the use of exogenous estrogen is associated with changes in the severity of diabetic retinopathy and the incidence of macular edema. RESEARCH DESIGN AND METHODS:The study design involved observation of two well-defined cohorts of women with diabetes. One group was diagnosed with diabet...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.22.12.1984
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To determine the occurrence of elevated fetal hemoglobin (HbF) among the diabetic population and determine the clinical situation of importance. RESEARCH DESIGN AND METHODS:A cross-sectional study was conducted. HbA1c and HbF were measured with high-performance liquid chromatography in 1,104 consecutive diab...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章
doi:10.2337/diacare.17.8.828
更新日期:1994-08-01 00:00:00
abstract:OBJECTIVE:To assess the success and baseline predictors of maintaining glycemic control for up to 5 years of therapy using basal insulin glargine or standard glycemic care in people with dysglycemia treated with zero or one oral glucose-lowering agents. RESEARCH DESIGN AND METHODS:Data from 12,537 participants in the ...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc12-2238
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:Several meta-analyses of observational studies suggested that metformin use reduces cancer risk in type 2 diabetes. However, this result was not confirmed by the few available randomized controlled trials (RCTs), and many observational studies on metformin and cancer were potentially afflicted with time-relat...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc14-0977
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To determine the incidence of insulin-dependent diabetes mellitus (IDDM) in children aged 0-14 years in Kuwait, as part of the World Health Organization Multinational Collaborative Study (DIAMOND), and to determine if the incidence rates have increased. RESEARCH DESIGN AND METHODS:All cases of IDDM diagnosed...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.18.7.923
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:Newer medications offer more options for glycemic control in type 2 diabetes. However, they come at considerable costs. We undertook a health economic analysis to better understand the value of adding two newer medications (exenatide and sitagliptin) as second-line therapy to glycemic control strategies for p...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc09-1488
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:To examine patients' views of the acceptability of and satisfaction with telephone care center support provided to improve blood glucose control in type 2 diabetes. RESEARCH DESIGN AND METHODS:The Pro-Active Call-Center Treatment Support (PACCTS) Trial randomized patients from 47 general practices in a depri...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.28.2.283
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:Hypertriglyceridemia is associated with cardiovascular disease in diabetes. Fibrates effectively lower, but do not always normalize, serum triglyceride levels. Fish oil supplements may then be added to lower serum triglyceride levels. Doubt remains whether the net effect of fish oil intake on glycemic control...
journal_title:Diabetes care
pub_type: 杂志文章,meta分析
doi:10.2337/diacare.21.4.494
更新日期:1998-04-01 00:00:00
abstract:OBJECTIVE:To create a simple prediction rule that could perform as well as the 2-h postchallenge plasma glucose (PCPG) test to predict those at risk for diabetes. We created a prediction rule in one sample and prospectively validated it for incident diabetes in a separate cohort. RESEARCH DESIGN AND METHODS:A cross-se...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.28.2.404
更新日期:2005-02-01 00:00:00