Global Disability Burdens of Diabetes-Related Lower-Extremity Complications in 1990 and 2016.

abstract：OBJECTIVE:To examine if dual replacement with insulin and rhIGF-I, recombinant human insulin-like growth factor I (rhIGF-I) may be safe and result in improved metabolic control and reduced insulin usage. RESEARCH DESIGN AND METHODS:Forty-three patients with IDDM were randomized to receive a daily injection of rhIGF-I ...

journal_title：Diabetes care

authors： Quattrin T,Thrailkill K,Baker L,Litton J,Dwigun K,Rearson M,Poppenheimer M,Giltinan D,Gesundheit N,Martha P Jr

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Recent data suggest that residential environment may influence health behaviors and outcomes. We assessed whether perception of neighborhood problems was associated with diabetes behaviors and outcomes. RESEARCH DESIGN AND METHODS:This cross-sectional analysis included 7,830 diabetic adults enrolled in Trans...

journal_title：Diabetes care

authors： Gary TL,Safford MM,Gerzoff RB,Ettner SL,Karter AJ,Beckles GL,Brown AF

更新日期：2008-02-01 00:00:00

abstract：:Morphologic characteristics of insulin precipitates were examined by both scanning and transmission electron microscopy. Insulin precipitate obtained after 1 wk of in vivo storage in an implanted dog reservoir was compared with insulin precipitate produced in vitro by isoelectric precipitation, acid-freeze-heat precip...

journal_title：Diabetes care

authors： Schade DS,Eaton RP,DeLongo J,Saland LC,Ladman AJ,Carlson GA

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:Foot ulceration is a serious complication of diabetes, and new techniques that can predict wound healing may prove very helpful. We tested the ability of medical hyperspectral technology (HT), a novel diagnostic scanning technique that can quantify tissue oxy- and deoxyhemoglobin to predict diabetic foot ulce...

journal_title：Diabetes care

authors： Khaodhiar L,Dinh T,Schomacker KT,Panasyuk SV,Freeman JE,Lew R,Vo T,Panasyuk AA,Lima C,Giurini JM,Lyons TE,Veves A

更新日期：2007-04-01 00:00:00

abstract：:This study investigates and compares human insulin (recombinant DNA) and purified porcine insulin (PPI) in healthy volunteers and in type II diabetic patients, in terms of whether both these insulins were capable of influencing in a different manner pancreatic glucagon, C-peptide, and free fatty acids (FFA) concentrat...

journal_title：Diabetes care

authors： Raptis S,Hadjidakis D,Enzmann F,Raptis A,Diamantopoulos E,Rosenthal J

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:The goal of the study was to examine risk factors in the prediction of coronary heart disease (CHD) and differences in men and women in the EURODIAB Prospective Complications Study. RESEARCH DESIGN AND METHODS:Baseline risk factors and CHD at follow-up were assessed in 2,329 type 1 diabetic patients without ...

journal_title：Diabetes care

authors： Soedamah-Muthu SS,Chaturvedi N,Toeller M,Ferriss B,Reboldi P,Michel G,Manes C,Fuller JH,EURODIAB Prospective Complications Study Group.

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:This study uses novel methods to examine the frequency of diagnosis and treatment of prediabetes in real-world clinical settings using electronic health record (EHR) data. RESEARCH DESIGN AND METHODS:We identified a cohort of 358,120 adults with incident prediabetes (fasting plasma glucose [FPG] 100-125 mg/d...

journal_title：Diabetes care

authors： Schmittdiel JA,Adams SR,Segal J,Griffin MR,Roumie CL,Ohnsorg K,Grant RW,O'Connor PJ

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the prevalence of diabetes in pregnancy (gestational diabetes mellitus [GDM] and NIDDM) and to identify risk factors in the development of GDM in a native population in northwestern Ontario, Canada. RESEARCH DESIGN AND METHODS:A retrospective analysis of 1,305 singl...

journal_title：Diabetes care

authors： Harris SB,Caulfield LE,Sugamori ME,Whalen EA,Henning B

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:The risk of myocardial infarction (MI) in patients with diabetes is greater than for patients without diabetes. Consequently, prophylactic treatment is recommended for patients with diabetes and risk factors for ischemic heart disease. We aimed to estimate the risk of adverse cardiac events in patients with a...

journal_title：Diabetes care

authors： Olesen KKW,Madsen M,Egholm G,Thim T,Jensen LO,Raungaard B,Bøtker HE,Sørensen HT,Maeng M

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Early use of insulin after diagnosis of type 2 diabetes is met with resistance because of associated weight gain, hypoglycemia, and fear of decreased compliance and quality of life (QoL). RESEARCH DESIGN AND METHODS:In treatment-naive patients with newly diagnosed type 2 diabetes, insulin and metformin were ...

journal_title：Diabetes care

authors： Lingvay I,Legendre JL,Kaloyanova PF,Zhang S,Adams-Huet B,Raskin P

更新日期：2009-10-01 00:00:00

abstract：:Thirty-eight non-insulin-dependent diabetic patients within 130% of desirable body weight were given a 100-g oral glucose tolerance test (OGTT) at diagnosis and after at least 1 mo of dietary treatment with energy and carbohydrate restriction. Thirteen "responders" showed an improvement in fasting blood glucose, gluco...

journal_title：Diabetes care

authors： Sönksen PH,Lowy C,Perkins JR,Lim HS

更新日期：1984-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of lixisenatide versus placebo on glycemic control in older patients with type 2 diabetes uncontrolled on their current antidiabetic treatment. RESEARCH DESIGN AND METHODS:In this phase III, double-blind, randomized, placebo-controlled, two-arm, parallel-group, multicenter...

journal_title：Diabetes care

authors： Meneilly GS,Roy-Duval C,Alawi H,Dailey G,Bellido D,Trescoli C,Manrique Hurtado H,Guo H,Pilorget V,Perfetti R,Simpson H,GetGoal-O Trial Investigators.

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA). RESEARCH DESIGN AND METHODS:The CGMS enabled recording of subcutaneous g...

journal_title：Diabetes care

authors： Kessler L,Passemard R,Oberholzer J,Benhamou PY,Bucher P,Toso C,Meyer P,Penfornis A,Badet L,Wolf P,Colin C,Morel P,Pinget M,GRAGIL Group.

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To determine whether, after adjustment for glycemia and other selected covariates, hemoglobin A1c (HbA1c) differed among adults from six Hispanic/Latino heritage groups (Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American) and between Hispanic/Latino and non-Hispanic white adults wit...

journal_title：Diabetes care

authors： Avilés-Santa ML,Hsu LL,Arredondo M,Menke A,Werner E,Thyagarajan B,Heiss G,Teng Y,Schneiderman N,Giachello AL,Gallo LC,Talavera GA,Cowie CC

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:Recently, the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research Trial demonstrated that treatment with the angiotensin receptor blocker (ARB) valsartan for 5 years resulted in a relative reduction of 14% in the incidence of type 2 diabetes in subjects with impaired glucose metabolism (...

journal_title：Diabetes care

authors： van der Zijl NJ,Moors CC,Goossens GH,Hermans MM,Blaak EE,Diamant M

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To compare a simple meal plan emphasizing healthy food choices with a traditional exchange-based meal plan in reducing HbA(1c) levels in urban African Americans with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 648 patients with type 2 diabetes were randomized to receive instruction in either a he...

journal_title：Diabetes care

authors： Ziemer DC,Berkowitz KJ,Panayioto RM,El-Kebbi IM,Musey VC,Anderson LA,Wanko NS,Fowke ML,Brazier CW,Dunbar VG,Slocum W,Bacha GM,Gallina DL,Cook CB,Phillips LS

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:Some children with type 1 diabetes may be at risk of cognitive impairments, but mechanisms of this effect have not been confirmed. The objective of this study was to determine whether severe hypoglycemia (SH) in children with type 1 diabetes is associated with cognitive decline over 18 months. RESEARCH DESIG...

journal_title：Diabetes care

authors： Wysocki T,Harris MA,Mauras N,Fox L,Taylor A,Jackson SC,White NH

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To investigate whether the use of exogenous estrogen is associated with changes in the severity of diabetic retinopathy and the incidence of macular edema. RESEARCH DESIGN AND METHODS:The study design involved observation of two well-defined cohorts of women with diabetes. One group was diagnosed with diabet...

journal_title：Diabetes care

authors： Klein BE,Klein R,Moss SE

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To characterize immune checkpoint inhibitor-associated diabetes mellitus (ICI-DM) in a single-institution case series. RESEARCH DESIGN AND METHODS:Retrospective chart review of 18 patients with new-onset ICI-DM following anti-programmed cell death protein 1 (PD-1)/anti-programmed cell death protein ligand 1 ...

journal_title：Diabetes care

authors： Byun DJ,Braunstein R,Flynn J,Zheng J,Lefkowitz RA,Kanbour S,Girotra M

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:We investigated the efficacy and safety of the sodium glucose cotransporter 2 inhibitor, empagliflozin, added to multiple daily injections of insulin (MDI insulin) in obese patients with type 2 diabetes mellitus (T2DM). RESEARCH DESIGN AND METHODS:Patients inadequately controlled on MDI insulin ± metformin (...

journal_title：Diabetes care

authors： Rosenstock J,Jelaska A,Frappin G,Salsali A,Kim G,Woerle HJ,Broedl UC,EMPA-REG MDI Trial Investigators.

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:After a 6-week placebo baseline period, 102 hypertensive NIDDM patients were ...

journal_title：Diabetes care

authors： Chan JC,Nicholls MG,Cheung CK,Law LK,Swaminathan R,Cockram CS

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of taspoglutide (R1583/BIM51077), a human once-weekly glucagon-like peptide-1 analog, in patients with type 2 diabetes inadequately controlled with metformin. RESEARCH DESIGN AND METHODS:Type 2 diabetic (n = 306) patients who failed to obtain glycemic control (A1C 7-9.5%) ...

journal_title：Diabetes care

authors： Nauck MA,Ratner RE,Kapitza C,Berria R,Boldrin M,Balena R

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:Blood pressure ranges associated with cardiovascular disease (CVD) events in advanced type 2 diabetes are not clear. Our objective was to determine whether baseline and follow-up (On-Study) systolic blood pressure (SBP), diastolic blood pressure (DBP), and SBP combined with DBP predict CVD events in the Veter...

journal_title：Diabetes care

authors： Anderson RJ,Bahn GD,Moritz TE,Kaufman D,Abraira C,Duckworth W,VADT Study Group.

更新日期：2011-01-01 00:00:00

abstract：:Sixty-two subjects having either insulin-dependent or non-insulin-dependent diabetes completed a randomized, double-blind study comparing effects of aspartame or a placebo on blood glucose control. Twenty-nine subjects consumed 2.7 g aspartame per day for 18 wk, given as aspartame-containing capsules with meals, while...

journal_title：Diabetes care

authors： Nehrling JK,Kobe P,McLane MP,Olson RE,Kamath S,Horwitz DL

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:Some evidence suggests an inverse association between type 2 diabetes and androgens in men and a positive association between type 2 diabetes and androgens in women. The purpose of this community-based study was to evaluate sex differences in the association between endogenous total and bioavailable estrogen ...

journal_title：Diabetes care

authors： Goodman-Gruen D,Barrett-Connor E

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:To study the effect of water diuresis on renal medullary and cortical oxygenation in patients with diabetes using blood oxygenation level--dependent magnetic resonance imaging (BOLD MRI). RESEARCH DESIGN AND METHODS:Nine mild diabetic subjects (48 +/- 2.7 years of age, six women) and nine nondiabetic subjec...

journal_title：Diabetes care

authors： Epstein FH,Veves A,Prasad PV

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:In 2010, the American Diabetes Association (ADA) added hemoglobin A1c (A1C) to the guidelines for diagnosing type 2 diabetes. However, existing models for predicting diabetes risk were developed prior to the widespread adoption of A1C. Thus, it remains unknown how well existing diabetes risk prediction models...

journal_title：Diabetes care

authors： Lacy ME,Wellenius GA,Carnethon MR,Loucks EB,Carson AP,Luo X,Kiefe CI,Gjelsvik A,Gunderson EP,Eaton CB,Wu WC

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:Observational studies have associated metformin use with a decreased risk of lung cancer incidence in patients with type 2 diabetes, but the studies had important methodological shortcomings. The objective of this study was to determine whether metformin use is associated with a decreased risk of lung cancer ...

journal_title：Diabetes care

authors： Smiechowski BB,Azoulay L,Yin H,Pollak MN,Suissa S

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To review the current knowledge about nonpharmacologic approaches in the prevention and early treatment of type 2 diabetes. RESEARCH DESIGN AND METHODS:This study reviewed the research reports dealing with nonpharmacologic interventions aimed at preventing type 2 diabetes with early lifestyle interventions. ...

journal_title：Diabetes care

authors： Tuomilehto J

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate alcohol consumption in relation to the incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS:The study population consisted of 22778 twins of the Finnish Twin Cohort. This cohort was compiled in 1975 and includes all same-sexed twins born in Finland before 1958. I...

journal_title：Diabetes care

authors： Carlsson S,Hammar N,Grill V,Kaprio J

更新日期：2003-10-01 00:00:00