The epidemiology of diabetes in pregnant Native Canadians. A risk profile.

abstract：OBJECTIVE:To assess the effects of empagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, on broad biological systems through proteomics. RESEARCH DESIGN AND METHODS:Aptamer-based proteomics was used to quantify 3,713 proteins in 144 paired plasma samples obtained from 72 participants across the ...

journal_title：Diabetes care

authors： Ferrannini E,Murthy AC,Lee YH,Muscelli E,Weiss S,Ostroff RM,Sattar N,Williams SA,Ganz P

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Independent association of chronic kidney disease (CKD) and proliferative diabetic retinopathy (PDR) with cardiovascular disease (CVD) has not been established. In the Joslin 50-Year Medalist study, characterizing individuals with type 1 diabetes for 50 years or more, we examined the associations of CKD and P...

journal_title：Diabetes care

authors： Gordin D,Harjutsalo V,Tinsley L,Fickweiler W,Sun JK,Forsblom C,Amenta PS,Pober D,D'Eon S,Khatri M,Stillman IE,Groop PH,Keenan HA,King GL

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:It is known that continuous glucose monitoring (CGM) systems can lower mean glucose compared with episodic self-monitoring of blood glucose. Implantable CGM systems may provide additional benefits. RESEARCH DESIGN AND METHODS:We studied the Eversense (Senseonics Inc.) implantable CGM sensor in 71 participant...

journal_title：Diabetes care

authors： Kropff J,Choudhary P,Neupane S,Barnard K,Bain SC,Kapitza C,Forst T,Link M,Dehennis A,DeVries JH

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:The impact of major affective disorders on the effectiveness of diabetes prevention programs at promoting health behaviors has not been established. We investigated whether depression modifies the effectiveness of two pragmatic diabetes prevention programs at promoting increased physical activity. RESEARCH D...

journal_title：Diabetes care

authors： Yates T,Gray LJ,Henson J,Edwardson CL,Khunti K,Davies MJ

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:There is enough evidence that physical activity is an effective therapeutic tool in the management of type 2 diabetes. The present study was designed to validate a counseling strategy that could be used by physicians in their daily outpatient practice to promote the adoption and maintenance of physical activi...

journal_title：Diabetes care

authors： Di Loreto C,Fanelli C,Lucidi P,Murdolo G,De Cicco A,Parlanti N,Santeusanio F,Brunetti P,De Feo P

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To evaluate whether there is a difference in the association between nonalcoholic fatty liver disease (NAFLD) and incident diabetes based on the presence of impaired fasting glucose. RESEARCH DESIGN AND METHODS:A total of 7,849 individuals (5,409 men and 2,440 women) without diabetes, who underwent comprehen...

journal_title：Diabetes care

authors： Bae JC,Rhee EJ,Lee WY,Park SE,Park CY,Oh KW,Park SW,Kim SW

更新日期：2011-03-01 00:00:00

abstract：:Historically, alcohol use by the diabetic patient has been controversial. Recent studies in the general population have shown an improvement in mortality with moderate alcohol intake (one to three drinks per day). This improved mortality is greatest in those individuals who have a higher risk of ischemic heart disease...

journal_title：Diabetes care

authors： Bell DS

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:We examined the association between high blood pressure and incident type 2 diabetes in African Americans and whites aged 35-54 years at baseline. RESEARCH DESIGN AND METHODS:We combined data from the Atherosclerosis Risk in Communities (ARIC) study, the Coronary Artery Risk Development in Young Adults (CARD...

journal_title：Diabetes care

authors： Wei GS,Coady SA,Goff DC Jr,Brancati FL,Levy D,Selvin E,Vasan RS,Fox CS

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:We sought to examine the mechanisms by which the addition of glargine insulin or rosiglitazone improves glycemic control in type 2 diabetic subjects poorly controlled on maximally effective doses of metformin plus sulfonylurea. RESEARCH DESIGN AND METHODS:Subjects (aged 47 +/- 11 years, BMI 31 +/- 5 kg/m(2),...

journal_title：Diabetes care

authors： Triplitt C,Glass L,Miyazaki Y,Wajcberg E,Gastaldelli A,De Filippis E,Cersosimo E,DeFronzo RA

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To examine the contribution of nerve-axon reflex-related vasodilation to total acetylcholine-induced vasodilation in the skin of normal and diabetic subjects. RESEARCH DESIGN AND METHODS:The skin microcirculation was evaluated at the forearm level in 69 healthy subjects and 42 nonneuropathic diabetic patient...

journal_title：Diabetes care

authors： Hamdy O,Abou-Elenin K,LoGerfo FW,Horton ES,Veves A

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:With increasing life expectancy in the U.S., it is important to know whether a longer life expectancy means a longer healthy life span or a prolonged period of later-life morbidity. This study examines changes in lifetime without diabetes, a leading cause of morbidity in later life. RESEARCH DESIGN AND METHO...

journal_title：Diabetes care

authors： Cunningham SA,Riosmena F,Wang J,Boyle JP,Rolka DB,Geiss LS

更新日期：2011-10-01 00:00:00

abstract：:In a patient with hyperthyroidism and newly diagnosed insulin-dependent diabetes mellitus (IDDM), insulin action and clearance were studied before the initiation of antithyroid treatment and at 3-mo intervals for 1 yr thereafter. The sequential euglycemic clamp technique (5 mM) was used with insulin infusion rates of ...

journal_title：Diabetes care

authors： Nijs HG,Radder JK,Frölich M,Krans HM

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:Raloxifene hydrochloride is a selective estrogen receptor modulator that to date has not been shown to cause hypertriglyceridemia in normal, diabetic, or hypertriglyceridemic women. This study was designed to assess the effect of raloxifene on serum triglycerides in postmenopausal women who have a history of ...

journal_title：Diabetes care

authors： Carr MC,Knopp RH,Brunzell JD,Wheeler BS,Zhu X,Lakshmanan M,Rosen AS,Anderson PW

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:Hypoxia plays a major pathogenic role in diabetic nephropathy (DN). We have investigated in this study the effect of hypoxia-inducible factor 1 α subunit (HIF1A) genetic polymorphisms on the development of DN. RESEARCH DESIGN AND METHODS:In 1,165 American type 1 diabetic patients with and without DN selected...

journal_title：Diabetes care

authors： Gu HF,Zheng X,Abu Seman N,Gu T,Botusan IR,Sunkari VG,Lokman EF,Brismar K,Catrina SB

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:We investigated the efficacy and safety of the sodium glucose cotransporter 2 inhibitor, empagliflozin, added to multiple daily injections of insulin (MDI insulin) in obese patients with type 2 diabetes mellitus (T2DM). RESEARCH DESIGN AND METHODS:Patients inadequately controlled on MDI insulin ± metformin (...

journal_title：Diabetes care

authors： Rosenstock J,Jelaska A,Frappin G,Salsali A,Kim G,Woerle HJ,Broedl UC,EMPA-REG MDI Trial Investigators.

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Acarbose inhibits alpha-glucosidases of the small intestine and thus delays glucose release from complex carbohydrates. Therefore, its efficacy and acceptability as a first-line drug in non-insulin-dependent diabetes mellitus (NIDDM) insufficiently treated with diet alone was tested in a randomized double-bli...

journal_title：Diabetes care

authors： Hanefeld M,Fischer S,Schulze J,Spengler M,Wargenau M,Schollberg K,Fücker K

更新日期：1991-08-01 00:00:00

abstract：:Intranasal glucagon can raise blood glucose levels in healthy subjects. The aims of this study were to 1) compare the hyperglycemic effect of intranasal and intramuscular glucagon in healthy subjects and type I (insulin-dependent) diabetes patients during euglycemic conditions and 2) test the efficacy of intranasal an...

journal_title：Diabetes care

authors： Pontiroli AE,Calderara A,Pajetta E,Alberetto M,Pozza G

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:To determine the effect of metformin on the acute metabolic response to submaximal exercise, the effect of exercise on plasma metformin concentrations, and the interaction between metformin and exercise on the subsequent response to a standardized meal. RESEARCH DESIGN AND METHODS:Ten participants with type ...

journal_title：Diabetes care

authors： Boulé NG,Robert C,Bell GJ,Johnson ST,Bell RC,Lewanczuk RZ,Gabr RQ,Brocks DR

更新日期：2011-07-01 00:00:00

abstract：:The issue of statin-associated cognitive impairment has been a hot topic among both patients and health care providers, especially since the U.S. Food and Drug Administration (FDA) issued a statement regarding rare postmarketing reports of ill-defined cognitive impairment associated with statin use. This statement was...

journal_title：Diabetes care

authors： Bitzur R

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To test the conclusion that there is no association between multiple episodes of severe hypoglycemia and cognitive decrements by reanalyzing the data from the Diabetes Control and Complications Trial (DCCT) with psychometrically validated cognitive factors and to conduct a novel analysis of the association be...

journal_title：Diabetes care

authors： Austin EJ,Deary IJ

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To examine the safety and efficacy of dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, added on to pioglitazone in type 2 diabetes inadequately controlled on pioglitazone. RESEARCH DESIGN AND METHODS:Treatment-naive patients or those receiving metformin, sulfonylurea, or thiazolidinedione entered a...

journal_title：Diabetes care

authors： Rosenstock J,Vico M,Wei L,Salsali A,List JF

更新日期：2012-07-01 00:00:00

abstract：:We examined the relationship between the thickness of the quadriceps muscle capillary basement membrane and diabetic retinopathy. Basement membrane thickness was measured in two groups of patients with long-standing type II diabetes mellitus. One group of patients (N = 13) had no evidence of diabetic retinopathy on fl...

journal_title：Diabetes care

authors： Klein RF,Feingold KR,Morgan C,Stern WH,Siperstein MD

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVE:1) To examine trends in the use of diabetes medications and 2) to determine whether physicians individualize diabetes treatment as recommended by the American Diabetes Association (ADA). RESEARCH DESIGN AND METHODS:We conducted a retrospective, cross-sectional analysis of 2003-2016 National Health and Nutrit...

journal_title：Diabetes care

authors： Le P,Chaitoff A,Misra-Hebert AD,Ye W,Herman WH,Rothberg MB

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To assess random venous blood glucose (RBG) measurement at antenatal booking to detect "overt diabetes in pregnancy" (ODIP). RESEARCH DESIGN AND METHODS:A retrospective analysis of regional hospital obstetric data from 2004-2008 was performed. Universal RBG screening was included at booking. Oral glucose tol...

journal_title：Diabetes care

authors： Church D,Halsall D,Meek C,Parker RA,Murphy HR,Simmons D

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:The objective of the study was to assess the efficacy and safety of repaglinide compared with placebo in the treatment of patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:This was a phase II multicenter, double-blind, placebo-controlled, randomized, dose-adjustment and maintenance trial. After scre...

journal_title：Diabetes care

authors： Goldberg RB,Einhorn D,Lucas CP,Rendell MS,Damsbo P,Huang WC,Strange P,Brodows RG

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:Prevalence and prognostic impact of cardiovascular disease differ between patients with or without diabetes. We aimed to explore differences in the prevalence and prognosis of myocardial ischemia by automated quantification of total perfusion deficit (TPD) among patients with and without diabetes. RESEARCH D...

journal_title：Diabetes care

authors： Han D,Rozanski A,Gransar H,Sharir T,Einstein AJ,Fish MB,Ruddy TD,Kaufmann PA,Sinusas AJ,Miller EJ,Bateman TM,Dorbala S,Di Carli M,Liang JX,Hu LH,Germano G,Dey D,Berman DS,Slomka PJ

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to examine the associations between the severity of hepatic steatosis and dyslipidemia in type 2 diabetes, including circulating apolipoprotein B100 (apoB) concentrations and lipoprotein particle size and numbers. RESEARCH DESIGN AND METHODS:Computed tomography imaging was use...

journal_title：Diabetes care

authors： Toledo FG,Sniderman AD,Kelley DE

更新日期：2006-08-01 00:00:00

abstract：:Japanese migrants and their offspring on the island of Hawaii and Japanese living in Hiroshima were examined for diabetes mellitus and its vascular complications. the same methods and investigators were used in both locations. Death certificates of Japanese and Caucasians dying on the island during the past 26 yr were...

journal_title：Diabetes care

authors： Kawate R,Yamakido M,Nishimoto Y,Bennett PH,Hamman RF,Knowler WC

更新日期：1979-03-01 00:00:00

abstract：OBJECTIVE:To investigate ethnic differences in adiponectin and leptin concentration and to determine whether these adipokines and a high-glycemic index diet account for ethnic variation in insulin resistance. RESEARCH DESIGN AND METHODS:In 1,176 South Asian, Chinese, Aboriginal, and European Canadians, fasting blood s...

journal_title：Diabetes care

authors： Mente A,Razak F,Blankenberg S,Vuksan V,Davis AD,Miller R,Teo K,Gerstein H,Sharma AM,Yusuf S,Anand SS,Study of the Health Assessment And Risk Evaluation.,Study of the Health Assessment And Risk Evaluation in Aboriginal Peoples Inv

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:To assess performance of nonfasting tests to screen children for dysglycemia (prediabetes or diabetes). RESEARCH DESIGN AND METHODS:This was a cross-sectional study of 254 overweight or obese (BMI ≥85th percentile) children aged 10-17 years. Subjects came for two visits to a clinical research unit. For visit...

journal_title：Diabetes care

authors： Lee JM,Gebremariam A,Wu EL,LaRose J,Gurney JG

更新日期：2011-12-01 00:00:00