Metformin and exercise in type 2 diabetes: examining treatment modality interactions.

abstract：OBJECTIVE:The study aim was to determine if multisystemic therapy (MST), an intensive home-based psychotherapy, could reduce hospital admissions for diabetic ketoacidosis (DKA) in youth with poorly controlled type 1 diabetes over 24 months. Potential cost savings from reductions in admissions were also evaluated. RESE...

journal_title：Diabetes care

authors： Ellis D,Naar-King S,Templin T,Frey M,Cunningham P,Sheidow A,Cakan N,Idalski A

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:There is substantial evidence that glucose intolerance is associated with an increased risk of cardiovascular disease. However, it is not well established whether plasma glucose is independently related to atherosclerosis when glucose tolerance is normal and, if so, to which stage of the complex atherosclerot...

journal_title：Diabetes care

authors： Bonora E,Kiechl S,Willeit J,Oberhollenzer F,Egger G,Bonadonna R,Muggeo M

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To estimate the within-person variability (SDi) for the overnight urinary albumin excretion rate (AER) in diabetic patients with persistent microalbuminuria. RESEARCH DESIGN AND METHODS:Thirteen normotensive diabetic patients in stable medical control, with normal renal function and without any associated ca...

journal_title：Diabetes care

authors： Phillipou G,Phillips PJ

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:Ethnic differences in type 2 diabetes risk between South Asians and white Europeans originate before adult life and are not fully explained by higher adiposity levels in South Asians. Although metabolic sensitivity to adiposity may differ between ethnic groups, this has been little studied in childhood. We ha...

journal_title：Diabetes care

authors： Nightingale CM,Rudnicka AR,Owen CG,Wells JC,Sattar N,Cook DG,Whincup PH

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to identify predictors of the onset of disturbed eating behavior (DEB) in adolescent girls with type 1 diabetes. RESEARCH DESIGN AND METHODS:In this prospective study, participants completed the Children's Eating Disorder Examination interview and self-report measures at baselin...

journal_title：Diabetes care

authors： Olmsted MP,Colton PA,Daneman D,Rydall AC,Rodin GM

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To study the metabolic effect and the variability of the effect elicited by inhalation of 87.2 U insulin powder combined with an absorption enhancer. The metabolic effect was compared with that of 10.2 U regular insulin injected subcutaneously and of 5.5 U regular insulin given intravenously RESEARCH DESIGN ...

journal_title：Diabetes care

authors： Heinemann L,Klappoth W,Rave K,Hompesch B,Linkeschowa R,Heise T

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To investigate whether the presence of antibody markers at diagnosis could help predict the rapid decrease in residual beta-cell function noted in some, but not all, patients with recent-onset type 1 diabetes. RESEARCH DESIGN AND METHODS:We measured random C-peptide levels (radioimmunoassay); islet cell cyto...

journal_title：Diabetes care

authors： Decochez K,Keymeulen B,Somers G,Dorchy H,De Leeuw IH,Mathieu C,Rottiers R,Winnock F,ver Elst K,Weets I,Kaufman L,Pipeleers DG,Gorus FK,Belgian Diabetes Registry.

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Left ventricular diastolic dysfunction (LVDD) is considered to be common in patients with type 2 diabetes mellitus (T2DM), but information on its progression over time is lacking. We studied the longitudinal development of left ventricular diastolic function (LVDF) and myocardial blood flow reserve in patient...

journal_title：Diabetes care

authors： Venskutonyte L,Jarnert C,Rydén L,Kjellström B

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To determine whether diabetes risk is influenced by which parent (a parental history of diabetes is a well-documented risk factor for NIDDM) is reported to have diabetes. RESEARCH DESIGN AND METHODS:We compared the prevalence of NIDDM and IGT for 4914 subjects according to their parental history of diabetes ...

journal_title：Diabetes care

authors： Mitchell BD,Valdez R,Hazuda HP,Haffner SM,Monterrosa A,Stern MP

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence and clinical associations of impaired awareness of hypoglycemia in a population-based sample of children and adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS:A validated questionnaire was administered to 656 patients with type 1 diabetes over a 6-month period to deter...

journal_title：Diabetes care

authors： Ly TT,Gallego PH,Davis EA,Jones TW

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:In view of the previously described anti-inflammatory effects of insulin, we investigated the potential suppressive effect of insulin on plasma concentrations and expression of the chemokines, monocyte chemoattractant protein-1 (MCP-1) and regulated on activation normal T-cell expressed and secreted (RANTES) ...

journal_title：Diabetes care

authors： Ghanim H,Korzeniewski K,Sia CL,Abuaysheh S,Lohano T,Chaudhuri A,Dandona P

更新日期：2010-05-01 00:00:00

abstract：:This commentary/review briefly considers the diverse criteria recommended for classification of overweight infants. Macrosomia continues to be a vexing problem for both obstetricians and pediatricians. Among the various techniques possible for use in assessing body composition, none are more practical than body weight...

journal_title：Diabetes care

authors： Schwartz R,Teramo KA

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To compare a simple meal plan emphasizing healthy food choices with a traditional exchange-based meal plan in reducing HbA(1c) levels in urban African Americans with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 648 patients with type 2 diabetes were randomized to receive instruction in either a he...

journal_title：Diabetes care

authors： Ziemer DC,Berkowitz KJ,Panayioto RM,El-Kebbi IM,Musey VC,Anderson LA,Wanko NS,Fowke ML,Brazier CW,Dunbar VG,Slocum W,Bacha GM,Gallina DL,Cook CB,Phillips LS

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:Uncertainty remains regarding the predictive value of various glycemic measures as they relate to the risk of diabetes and its complications. Using the cutoffs recommended by the American Diabetes Association's 2010 criteria, we determined the associations of fasting plasma glucose (FPG), 2-h postload glucose...

journal_title：Diabetes care

authors： Lu J,He J,Li M,Tang X,Hu R,Shi L,Su Q,Peng K,Xu M,Xu Y,Chen Y,Yu X,Yan L,Wang T,Zhao Z,Qin G,Wan Q,Chen G,Dai M,Zhang D,Gao Z,Wang G,Shen F,Luo Z,Qin Y,Chen L,Huo Y,Li Q,Ye Z,Zhang Y,Du R,Che

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To describe an etiologic approach to classification of diabetes types in youth based on the 1997 American Diabetes Association (ADA) framework, using data from the SEARCH for Diabetes in Youth Study. RESEARCH DESIGN AND METHODS:SEARCH conducted a comprehensive assessment of 2,291 subjects aged <20 years with...

journal_title：Diabetes care

authors： Dabelea D,Pihoker C,Talton JW,D'Agostino RB Jr,Fujimoto W,Klingensmith GJ,Lawrence JM,Linder B,Marcovina SM,Mayer-Davis EJ,Imperatore G,Dolan LM,SEARCH for Diabetes in Youth Study.

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:The objective of this analysis was to evaluate the impact of several classes of oral antihyperglycemic therapy relative to sulfonylurea monotherapy on all-cause mortality among a cohort of patients with diabetes from the Veterans Health Administration (VHA). RESEARCH DESIGN AND METHODS:A retrospective cohort...

journal_title：Diabetes care

authors： Kahler KH,Rajan M,Rhoads GG,Safford MM,Demissie K,Lu SE,Pogach LM

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Statins may reduce the risk of diabetic polyneuropathy (DPN) as a result of lipid-lowering and anti-inflammatory effects, but statins have also been associated with neurotoxicity. We examined whether statin therapy affects the risk of DPN. RESEARCH DESIGN AND METHODS:We identified all Danish patients with in...

journal_title：Diabetes care

authors： Kristensen FP,Christensen DH,Callaghan BC,Kahlert J,Knudsen ST,Sindrup SH,Feldman EL,Østergaard L,Andersen H,Jensen TS,Sørensen HT,Thomsen RW

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:The sulfonylurea (SU) glyburide may cause severe and prolonged episodes of hypoglycemia. We aimed at investigating the impact of glyburide on glucose counterregulatory hormones during stepwise hypoglycemic clamp studies. RESEARCH DESIGN AND METHODS:We performed stepwise hypoglycemic clamp studies in 16 healt...

journal_title：Diabetes care

authors： ter Braak EW,Appelman AM,van der Tweel I,Erkelens DW,van Haeften TW

更新日期：2002-01-01 00:00:00

abstract：:Coronary heart disease is the leading cause of death among patients with non-insulin-dependent diabetes mellitus (NIDDM). NIDDM patients have a high frequency of dyslipidemia, which along with obesity, hypertension, and hyperglycemia may contribute significantly to accelerated coronary atherosclerosis. Because risk fa...

journal_title：Diabetes care

authors： Garg A,Grundy SM

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVE:High plasma adiponectin is associated with reduced risk of type 2 diabetes, probably a consequence of its insulin-sensitizing properties. In vivo data in rodents suggest that the insulin-sensitization responsible for improvement of glycemia occurs in muscle and liver. Whereas associations of plasma adiponecti...

journal_title：Diabetes care

authors： Stefan N,Stumvoll M,Vozarova B,Weyer C,Funahashi T,Matsuzawa Y,Bogardus C,Tataranni PA

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:Subjects with type 1 diabetes are at high risk for many long-term complications, including early mortality and coronary artery disease (CAD). Few data are available on which to base goal levels for two major risk factors, namely blood pressure and lipid/lipoproteins. The objective of this study was to determi...

journal_title：Diabetes care

authors： Orchard TJ,Forrest KY,Kuller LH,Becker DJ,Pittsburgh Epidemiology of Diabetes Complications Study.

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:Individuals with type 2 diabetes have high risk of late-life cognitive impairment, yet little is known about strategies to modify risk. Targeting insulin resistance and vascular complications-both associated with cognitive decline-may be a productive approach. We investigated whether dietary fat, which modula...

journal_title：Diabetes care

authors： Devore EE,Stampfer MJ,Breteler MM,Rosner B,Kang JH,Okereke O,Hu FB,Grodstein F

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To describe market trends for antidiabetic drugs, focusing on newly approved drugs, concomitant use of antidiabetic drugs, and effects of safety concerns and access restrictions on thiazolidinedione use. RESEARCH DESIGN AND METHODS:Nationally projected data on antidiabetic prescriptions for adults dispensed ...

journal_title：Diabetes care

authors： Hampp C,Borders-Hemphill V,Moeny DG,Wysowski DK

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:We sought to examine the mechanisms by which the addition of glargine insulin or rosiglitazone improves glycemic control in type 2 diabetic subjects poorly controlled on maximally effective doses of metformin plus sulfonylurea. RESEARCH DESIGN AND METHODS:Subjects (aged 47 +/- 11 years, BMI 31 +/- 5 kg/m(2),...

journal_title：Diabetes care

authors： Triplitt C,Glass L,Miyazaki Y,Wajcberg E,Gastaldelli A,De Filippis E,Cersosimo E,DeFronzo RA

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to compare clinical and biomechanical characteristics of balance in diabetic polyneuropathic elderly patients and normal age-matched subjects. RESEARCH DESIGN AND METHODS:Fifteen elderly with distal neuropathy (DNP) and 15 healthy age-matched subjects were evaluated with the b...

journal_title：Diabetes care

authors： Corriveau H,Prince F,Hébert R,Raîche M,Tessier D,Maheux P,Ardilouze JL

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:In this prospective, randomized, open trial, we compared the efficacy and safety of aspart insulin given subcutaneously at different time intervals to a standard low-dose intravenous (IV) infusion protocol of regular insulin in patients with uncomplicated diabetic ketoacidosis (DKA). RESEARCH DESIGN AND METH...

journal_title：Diabetes care

authors： Umpierrez GE,Cuervo R,Karabell A,Latif K,Freire AX,Kitabchi AE

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the accuracy of the UK Prospective Diabetes Study Outcomes Model (UKPDS-OM) in predicting clinical outcomes during the UKPDS posttrial monitoring (PTM) period. RESEARCH DESIGN AND METHODS:At trial end in 1997, the 4,031 surviving UKPDS patients, of the 5,102 originally enrolled in the study, retu...

journal_title：Diabetes care

authors： Leal J,Hayes AJ,Gray AM,Holman RR,Clarke PM

更新日期：2013-06-01 00:00:00

abstract：:The clinical diagnosis of new-onset type 1 diabetes has, for many years, been considered relatively straightforward. Recently, however, there is increasing awareness that within this single clinical phenotype exists considerable heterogeneity: disease onset spans the complete age range; genetic susceptibility is compl...

journal_title：Diabetes care

authors： Battaglia M,Ahmed S,Anderson MS,Atkinson MA,Becker D,Bingley PJ,Bosi E,Brusko TM,DiMeglio LA,Evans-Molina C,Gitelman SE,Greenbaum CJ,Gottlieb PA,Herold KC,Hessner MJ,Knip M,Jacobsen L,Krischer JP,Long SA,Lundgren M

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare different outcome measures in the audit of management of diabetic foot ulcers RESEARCH DESIGN AND METHODS:Data collected prospectively in a consecutive cohort of patients referred to a specialist multidisciplinary foot care clinic between 1 January 2000 and 31 Decembe...

journal_title：Diabetes care

authors： Jeffcoate WJ,Chipchase SY,Ince P,Game FL

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess racial/ethnic variation in access to health care, use of particular health care services, presence of cardiovascular risk factors, and perceptions of health and impairment among women at risk for type 2 diabetes because of their histories of gestational diabetes mellitu...

journal_title：Diabetes care

authors： Kim C,Sinco B,Kieffer EA

更新日期：2007-06-01 00:00:00