Effect of diabetes on renal medullary oxygenation during water diuresis.

abstract：OBJECTIVE:Newer medications offer more options for glycemic control in type 2 diabetes. However, they come at considerable costs. We undertook a health economic analysis to better understand the value of adding two newer medications (exenatide and sitagliptin) as second-line therapy to glycemic control strategies for p...

journal_title：Diabetes care

authors： Sinha A,Rajan M,Hoerger T,Pogach L

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the role of metabolic control in the progression of diabetic retinopathy during pregnancy. RESEARCH DESIGN AND METHODS:We conducted a prospective cohort study of 155 diabetic women in the Diabetes in Early Pregnancy Study followed from the periconceptional period to 1 month postpartum. Fundus pho...

journal_title：Diabetes care

authors： Chew EY,Mills JL,Metzger BE,Remaley NA,Jovanovic-Peterson L,Knopp RH,Conley M,Rand L,Simpson JL,Holmes LB

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:The racial impact on graft outcome is not well defined in diabetic recipients. The purpose of this study is to analyze our experience with kidney-alone (A) and kidney-pancreas (KP) transplantation in type 1 diabetic recipients and evaluate the impact of racial disparity on outcome. RESEARCH DESIGN AND METHOD...

journal_title：Diabetes care

authors： Douzdjian V,Bhaskar SS,Baliga PK,Gugliuzza KK,Rajagopalan PR

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVE:To investigate the association between vitamin D status, assessed by plasma 25-hydroxyvitamin D, and risk of incident diabetes. RESEARCH DESIGN AND METHODS:Prospective observational study with a mean follow-up of 2.7 years in the Diabetes Prevention Program (DPP), a multicenter trial comparing different stra...

journal_title：Diabetes care

authors： Pittas AG,Nelson J,Mitri J,Hillmann W,Garganta C,Nathan DM,Hu FB,Dawson-Hughes B,Diabetes Prevention Program Research Group.

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of a lifestyle intervention program that can be readily translated into clinical practice for obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:The study consisted of a 12-month randomized controlled trial of 147 health plan members with type 2 diabetes and obesity (BMI ...

journal_title：Diabetes care

authors： Wolf AM,Conaway MR,Crowther JQ,Hazen KY,L Nadler J,Oneida B,Bovbjerg VE,Improving Control with Activity and Nutrition (ICAN) Study.

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To explore the nature of functional impairment in older people with diabetes. RESEARCH DESIGN AND METHODS:A population-based case-control study with detailed assessment of diabetes and functional status was undertaken. RESULTS:Altogether, 403 case subjects and 403 matched control subjects were studied (medi...

journal_title：Diabetes care

authors： Sinclair AJ,Conroy SP,Bayer AJ

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Few multiple lifestyle behavior change programs have been designed to reduce the risk of coronary heart disease in postmenopausal women with type 2 diabetes. This study tested the effectiveness of the Mediterranean Lifestyle Program (MLP), a comprehensive lifestyle self-management program (Mediterranean low-s...

journal_title：Diabetes care

authors： Toobert DJ,Glasgow RE,Strycker LA,Barrera M Jr,Radcliffe JL,Wander RC,Bagdade JD

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:To determine whether reducing triglyceride concentrations in humans reduces serum insulin levels and consider the implications of this for the insulin resistance of hypertriglyceridemia. RESEARCH DESIGN AND METHODS:Insulin and glucose levels were determined during an oral glucose tolerance test (OGTT) in 14 ...

journal_title：Diabetes care

authors： Steiner G

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVE:We have demonstrated high heritability of insulin secretion measured as acute insulin response to glucose times insulin sensitivity (disposition index). Furthermore, we showed that obese normoglycemic family members of a type 2 diabetic proband failed to compensate for the insulin resistance of obesity by inc...

journal_title：Diabetes care

authors： Elbein SC,Sun J,Scroggin E,Teng K,Hasstedt SJ

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:Antioxidant trials have not demonstrated efficacy in slowing cardiovascular disease but could not rule out benefit for specific patient subgroups. Antioxidant therapy reduces LDL oxidizability in haptoglobin 1 allele homozygotes (Hp 1-1), but not in individuals with the haptoglobin 2 allele (Hp 2-1 or Hp 2-2)...

journal_title：Diabetes care

authors： Levy AP,Friedenberg P,Lotan R,Ouyang P,Tripputi M,Higginson L,Cobb FR,Tardif JC,Bittner V,Howard BV

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:Patients with diabetes due to hepatocyte nuclear factor (HNF)-1alpha mutations have beta-cell deficiency, insulin sensitivity, altered proinsulin levels, and a low renal threshold for glucose. It is uncertain how many of these features precede the development of diabetes. The aim of our study was to test for ...

journal_title：Diabetes care

authors： Stride A,Ellard S,Clark P,Shakespeare L,Salzmann M,Shepherd M,Hattersley AT

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence of NIDDM and IGT in the urban and rural areas in southern India. RESEARCH DESIGN AND METHODS:Two populations of the same ethnic background, but different socioeconomic background were chosen for this study. Nine-hundred urban people and 1038 rural subjects were studied. Fasting and...

journal_title：Diabetes care

authors： Ramachandran A,Snehalatha C,Dharmaraj D,Viswanathan M

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:To determine if differing beliefs about high blood glucose exist and are associated with blood glucose control among rural African-Americans. RESEARCH DESIGN AND METHODS:A community-based sample of rural African-Americans completed a survey, and a subsample underwent a subsequent screening that included gluc...

journal_title：Diabetes care

authors： Schorling JB,Saunders JT

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:No study has reported global disability burden estimates for individual diabetes-related lower-extremity complications (DRLECs). The Global Burden of Disease (GBD) study presents a robust opportunity to address this gap. RESEARCH DESIGN AND METHODS:GBD 2016 data, including prevalence and years lived with dis...

journal_title：Diabetes care

authors： Zhang Y,Lazzarini PA,McPhail SM,van Netten JJ,Armstrong DG,Pacella RE

更新日期：2020-05-01 00:00:00

abstract：:Specialists in childhood diabetes in North America were queried about the need for residential facilities for their patients with recurrent hospitalizations and school deficits due to family coping problems. Of 132 respondents, 115 indicated a need for 5-12% of their patients, a total of 530, close to the estimate of ...

journal_title：Diabetes care

authors： Rosenbloom AL

更新日期：1982-09-01 00:00:00

abstract：OBJECTIVE:We assessed the association between different blood lipid measures and risk of fatal/nonfatal coronary heart disease (CHD). RESEARCH DESIGN AND METHODS:We conducted an observational study of patients with type 2 diabetes from the Swedish National Diabetes Register. Baseline LDL cholesterol, non-HDL cholester...

journal_title：Diabetes care

authors： Eliasson B,Cederholm J,Eeg-Olofsson K,Svensson AM,Zethelius B,Gudbjörnsdottir S,National Diabetes Register.

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Diabetes eliminates the protective effect of female sex on the risk of coronary heart disease (CHD). We assessed sex differences in the treatment of CHD risk factors among patients with diabetes. RESEARCH DESIGN AND METHODS:A cross-sectional analysis included 3,849 patients with diabetes treated in five acad...

journal_title：Diabetes care

authors： Wexler DJ,Grant RW,Meigs JB,Nathan DM,Cagliero E

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:The incidence rate of childhood type 1 diabetes is thought to be increasing; however, Danish studies have not confirmed this. Using a national diabetes register initiated in 1996 and two previous regional incidence studies, we studied the age-specific incidence of type 1 diabetes over 30 years. Here, we descr...

journal_title：Diabetes care

authors： Svensson J,Carstensen B,Mølbak A,Christau B,Mortensen HB,Nerup J,Borch-Johnsen K

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To investigate whether the fall in soluble L-selectin (sL-selectin) level constitutes a marker for myocardial ischemia. RESEARCH DESIGN AND METHODS:The levels of soluble forms of adhesion molecules, i.e., intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), E-selectin (sE...

journal_title：Diabetes care

authors： Albertini JP,Valensi P,Lormeau B,Vaysse J,Attali JR,Gattegno L

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Elevated heart rate has been predictive of cardiovascular disease and has been proposed as a global index of the autonomic nervous system influence on the heart. Hyperinsulinism has been shown to trigger sympathetic activity experimentally; however, the clinical and epidemiological data on the association of ...

journal_title：Diabetes care

authors： Festa A,D'Agostino R Jr,Hales CN,Mykkänen L,Haffner SM

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:We compared the risk of cardiovascular disease (CVD) and all-cause mortality in subgroups of prediabetes defined by fasting plasma glucose (FPG), 2-h plasma glucose (2hPG), or HbA1c. RESEARCH DESIGN AND METHODS:In the Whitehall II cohort, 5,427 participants aged 50-79 years and without diabetes were followed...

journal_title：Diabetes care

authors： Vistisen D,Witte DR,Brunner EJ,Kivimäki M,Tabák A,Jørgensen ME,Færch K

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of female sexual dysfunction (FSD) in diabetic and nondiabetic Jordanian women. RESEARCH DESIGN AND METHODS:Data were collected from 1,137 married women using the Arabic translation of the Female Sexual Function Index questionnaire. RESULTS:Prevalence of sexual dysfunction in diab...

journal_title：Diabetes care

authors： Abu Ali RM,Al Hajeri RM,Khader YS,Shegem NS,Ajlouni KM

更新日期：2008-08-01 00:00:00

abstract：:OBJECTIVE The American Diabetes Association advocates insulin regimens for youth with type 1 diabetes that involve adjusting insulin dose based on carbohydrate intake and blood glucose level. Implementing these regimens requires knowledge about carbohydrate content of foods and subsequent calculations of insulin dose,...

journal_title：Diabetes care

authors： Koontz MB,Cuttler L,Palmert MR,O'Riordan M,Borawski EA,McConnell J,Kern EO

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between plasma IGF-1 and interleukin-6 (IL-6) levels in Caucasian nondiabetic subjects and evaluate the association of IGF-1 and IL-6 with the cardiometabolic risk factors characterizing metabolic syndrome (MetS). RESEARCH DESIGN AND METHODS:The study group consisted of 186 Caucas...

journal_title：Diabetes care

authors： Succurro E,Andreozzi F,Sciacqua A,Hribal ML,Perticone F,Sesti G

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Epidemiological evidence suggests that genetic factors can affect the course of type 1 diabetes complications produced by long-lasting hyperglycemia. In this review, the current strategies applicable to identifying these genetic factors are examined, as are recent findings on the genetics of diabetic nephropa...

journal_title：Diabetes care

authors： Marre M

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between the use of ACE inhibitors and hospital admission for severe hypoglycemia and to explore the effects of potential confounding variables on this relationship. RESEARCH DESIGN AND METHODS:The association between the use of ACE inhibitors and the incidence of hypoglycemia is c...

journal_title：Diabetes care

authors： Morris AD,Boyle DI,McMahon AD,Pearce H,Evans JM,Newton RW,Jung RT,MacDonald TM

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:The purpose of the 1992 Singapore National Health Survey was to determine the current distribution of major noncommunicable diseases and their risk factors, including the prevalence of diabetes and dyslipidemia, in Singapore. RESEARCH DESIGN AND METHODS:A combination of disproportionate stratified sampling a...

journal_title：Diabetes care

authors： Tan CE,Emmanuel SC,Tan BY,Jacob E

更新日期：1999-02-01 00:00:00

abstract：:The concept of gestational diabetes goes back at least to 1946. Over the years, sophistication has increased regarding the pathophysiology of this condition. However, there is not universal agreement on how to diagnose gestational diabetes. The most widely used diagnostic criteria in the U.S. were validated by their p...

journal_title：Diabetes care

authors： Coustan DR,Carpenter MW

更新日期：1998-08-01 00:00:00

abstract：:Core Outcome Sets (COS) contain an agreed minimum set of outcomes to be measured and reported in all studies in a specific area, with the objective of standardizing outcome reporting. COS may minimize research waste by identifying outcomes important to key stakeholders, allowing for improved evidence synthesis, and fa...

journal_title：Diabetes care

authors： Egan AM,Bogdanet D,Biesty L,Kgosidialwa O,McDonagh C,O'Shea C,O'Shea PM,Devane D,Dunne FP,INSPIRED research group.

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:A1C is associated with diabetes complications but does not reflect glycemic variability (GV), which may worsen outcomes by inducing inflammation, oxidative stress, and cardiac arrhythmias. We tested whether a glucagon-like peptide 1 agonist-based regimen can reduce GV and cardiometabolic risk markers while ma...

journal_title：Diabetes care

authors： FLAT-SUGAR Trial Investigators.

更新日期：2016-06-01 00:00:00