Abstract:
OBJECTIVE:The purpose of the 1992 Singapore National Health Survey was to determine the current distribution of major noncommunicable diseases and their risk factors, including the prevalence of diabetes and dyslipidemia, in Singapore. RESEARCH DESIGN AND METHODS:A combination of disproportionate stratified sampling and systematic sampling were used to select the sample for the survey. The final number of respondents was 3,568, giving a response rate of 72.6%. All subjects fasted for 10 h and were given a 75-g glucose load, except those known to have diabetes. Blood was taken before and 2 h after the glucose load. Diagnosis of diabetes was based on 2-h glucose alone. RESULTS:The age-standardized prevalence of diabetes in Singapore residents aged 18-69 years was 8.4%, with more than half (58.5%) previously undiagnosed. Prevalence of diabetes was high across all three ethnic groups. The prevalence of impaired glucose tolerance was 16.1%, that of hypertension was 6.5%, and 19.0% were regular smokers. The total cholesterol (mean +/- SD) of nondiabetic Singaporeans was 5.18 +/- 1.02 mmol/l; 47.9% had cholesterol > 5.2 mmol/l, while 15.4% had levels > 6.3 mmol/l. Mean LDL cholesterol was 3.31 +/- 0.89 mmol/l; HDL cholesterol was 1.30 +/- 0.32 mmol/l, and triglyceride was 1.23 +/- 0.82 mmol/l. CONCLUSIONS:Prevalence of diabetes was high across all three ethnic groups. Ethnic differences in prevalence of diabetes, insulin resistance, central obesity, hypertension, smoking, and lipid profile could explain the differential coronary heart disease rates in the three major ethnic groups in Singapore.
journal_name
Diabetes Carejournal_title
Diabetes careauthors
Tan CE,Emmanuel SC,Tan BY,Jacob Edoi
10.2337/diacare.22.2.241subject
Has Abstractpub_date
1999-02-01 00:00:00pages
241-7issue
2eissn
0149-5992issn
1935-5548journal_volume
22pub_type
杂志文章相关文献
DIABETES CARE文献大全abstract:OBJECTIVE:To compare the efficacy of the diabetic retinopathy (DR) screening with digital camera by endocrinologists with that by specialist and resident ophthalmologists in terms of sensitivity, specificity, and level of "loss of chance." RESEARCH DESIGN AND METHODS:In a cross-sectional study, 500 adult diabetic pati...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc10-1373
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility and efficacy of a fully integrated hybrid closed-loop (HCL) system (Medtronic MiniMed Inc., Northridge, CA), in day and night closed-loop control in subjects with type 1 diabetes, both in an inpatient setting and during 6 days at diabetes camp. RESEARCH DESIGN AND METHODS:The Medt...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc14-3073
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between plasma IGF-1 and interleukin-6 (IL-6) levels in Caucasian nondiabetic subjects and evaluate the association of IGF-1 and IL-6 with the cardiometabolic risk factors characterizing metabolic syndrome (MetS). RESEARCH DESIGN AND METHODS:The study group consisted of 186 Caucas...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc08-0553
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:Left ventricular remodeling occurs immediately after MI, involving structural changes in noninfarcted segment. However, the residual left ventricular pump function in NIDDM patients after acute MI has not been clarified. The purpose of this study was to evaluate the difference in the process of left ventricul...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.15.11.1522
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVE:To determine whether perceived risk and other health beliefs held by individuals at high risk for developing NIDDM predict weight loss and behavior change during a behavioral weight loss program to reduce the risk of NIDDM. RESEARCH DESIGN AND METHODS:Health beliefs and objective risk factors for diabetes we...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.20.10.1533
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of gastric emptying on postprandial insulin requirement in insulin-dependent diabetes mellitus (IDDM) patients with and without gastroparesis. RESEARCH DESIGN AND METHODS:Postprandial insulin requirement and gastric emptying were simultaneously evaluated in five IDDM patients with gast...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章
doi:10.2337/diacare.17.8.901
更新日期:1994-08-01 00:00:00
abstract::OBJECTIVE-Impaired endothelial function of resistance and conduit arteries can be detected in patients with type 1 diabetes. We studied whether a persistent improvement of endothelial function can be achieved by regular physical training. RESEARCH DESIGN AND METHODS-The study included 26 patients with type 1 diabetes ...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章
doi:10.2337/diacare.25.10.1795
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the temporal patterns of cardiometabolic multimorbidity (CM) and depression in White Caucasians (WCs) and African Americans (AAs) with early-onset type 2 diabetes and their impact on long-term atherosclerotic cardiovascular disease (ASCVD). RESEARCH DESIGN AND METHODS:From U.S. electronic medical...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc20-2045
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:To evaluate glycemia and metrics of glucose variability in youth with type 1 diabetes, and to assess patterns of 24-h glucose variability according to pubertal status. RESEARCH DESIGN AND METHODS:Metrics of glycemia, glucose variability, and glucose patterns were assessed by using 4 weeks of continuous gluco...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc19-0083
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:Numerous publications have already demonstrated that diabetes is a risk factor for the development of periodontal diseases and various inflammatory lesions in the oral mucosa. A possible correlation between diabetes and oral premalignancies and tumors was examined in this study, as no literature data are avai...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.27.3.770
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:This study assessed the ability to distinguish between type 1 diabetes-affected individuals and their unaffected relatives using HLA and single nucleotide polymorphism (SNP) genotypes. RESEARCH DESIGN AND METHODS:Eight models, ranging from only the high-risk DR3/DR4 genotype to all significantly associated H...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc12-2284
更新日期:2013-09-01 00:00:00
abstract::OBJECTIVE Pharmacological profiles of biphasic insulin aspart 30/70 (BIAsp 30) once daily (OD), twice daily (b.i.d.), and three times daily (t.i.d.) were compared with other insulin regimens in two crossover glucose clamp studies of insulin-treated type 2 diabetic patients. RESEARCH DESIGNS AND METHODS Study 1 consist...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc09-0097
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:This study examined whether lipids modify the relationship between intensive glucose control (INT) and diabetic retinopathy (DR). RESEARCH DESIGN AND METHODS:The incidence and progression of DR were assessed in 858 of 1,791 participants with 7-field stereoscopic fundus photographs at baseline and 5 years lat...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc15-1897
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:Recent survey evidence suggests that sensory ataxia due to diabetic neuropathy may be a more frequent and serious problem than is commonly recognized. This view is further supported by research that confirms the major contribution of the somatosensory system to the control of posture. We therefore sought to d...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.17.12.1411
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:Patients with diabetes due to hepatocyte nuclear factor (HNF)-1alpha mutations have beta-cell deficiency, insulin sensitivity, altered proinsulin levels, and a low renal threshold for glucose. It is uncertain how many of these features precede the development of diabetes. The aim of our study was to test for ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.28.7.1751
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:The sulfonylurea (SU) glyburide may cause severe and prolonged episodes of hypoglycemia. We aimed at investigating the impact of glyburide on glucose counterregulatory hormones during stepwise hypoglycemic clamp studies. RESEARCH DESIGN AND METHODS:We performed stepwise hypoglycemic clamp studies in 16 healt...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.25.1.107
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between self-reported diabetes and the risk of breast cancer (BC) and its interaction with moderate-intensity physical activity in pre- and postmenopausal Mexican women. RESEARCH DESIGN AND METHODS:A population-based case-control study was conducted using 1,000 incident case subje...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc11-2362
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:Sustained excess BMI increases the risk of type 1 diabetes (T1D) in autoantibody-positive relatives without diabetes of patients. We tested whether elevated BMI also accelerates the progression of islet autoimmunity before T1D diagnosis. RESEARCH DESIGN AND METHODS:We studied 706 single autoantibody-positive...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc19-1167
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:To compare the diagnostic properties of a nonmydriatic 200° ultra-widefield scanning laser ophthalmoscope (SLO) versus mydriatic Early Treatment of Diabetic Retinopathy Study (ETDRS) 7-field photography for diabetic retinopathy (DR) screening. RESEARCH DESIGN AND METHODS:A consecutive series of 212 eyes of 1...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc12-0346
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of diabetes in Tohono O'odham pregnancies, and to assess the efficacy of early prenatal diabetes screening in populations with high rates of diabetes. RESEARCH DESIGN AND METHODS:All Tohono O'odham women receiving prenatal care at the Sells Service Unit who delivered a viable baby...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.16.1.318
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:To identify factors related to lipid testing among patients with diabetes who receive diabetes care from primary care physicians. RESEARCH DESIGN AND METHODS:North Carolina Medicare claims were used to identify individuals with diabetes who received diabetes care from primary care physicians. Lipid testing w...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.26.5.1369
更新日期:2003-05-01 00:00:00
abstract::Two-thirds of all deaths in developed countries are caused by the major noncommunicable diseases, e.g., cardiovascular disease, cancer, and non-insulin-dependent diabetes mellitus (NIDDM). There is increasing evidence that these diseases are a consequence of life-style change, and they have a number of risk factors in...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.11.3.258
更新日期:1988-03-01 00:00:00
abstract:OBJECTIVE:In a previous study, we found observational evidence of improvement in beta-cell function when rosiglitazone was added to a failing oral antihyperglycemic regimen consisting of sulfonylureas and metformin. To confirm our previous observations, we designed and performed a prospective, randomized, and controlle...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.27.11.2585
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:Maturity-onset diabetes of the young (MODY) due to variants in HNF1A is the most common type of monogenic diabetes. Frequent misdiagnosis results in missed opportunity to use sulfonylureas as first-line treatment. A nongenetic biomarker could improve selection of subjects for genetic testing and increase diag...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc18-0422
更新日期:2019-01-01 00:00:00
abstract::This review summarizes Session IV: Therapeutic Interventions of the Fourth International Gestational Diabetes Workshop and suggests intervention protocols based on the presentations at this meeting and the literature. The opinions of the six presenters and their interpretation of the review of the literature in their ...
journal_title:Diabetes care
pub_type: 杂志文章,评审
doi:
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVE:We aimed to investigate the differences in clinical characteristics and pharmacological treatment associated with the presence of diabetes in a large cohort of patients with dementia. RESEARCH DESIGN AND METHODS:A cross-sectional registry-based study was conducted using data from the Swedish Dementia Registr...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc16-2516
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To determine whether diabetes risk is influenced by which parent (a parental history of diabetes is a well-documented risk factor for NIDDM) is reported to have diabetes. RESEARCH DESIGN AND METHODS:We compared the prevalence of NIDDM and IGT for 4914 subjects according to their parental history of diabetes ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.16.9.1262
更新日期:1993-09-01 00:00:00
abstract:OBJECTIVE:Evidence that midregional fragment of pro-A-type natriuretic peptide (MR-proANP) is a marker of mortality in patients with type 2 diabetes is limited. Therefore, we aimed to investigate the capabilities of MR-proANP in predicting mortality. We also investigated whether MR-proANP influences the relationship be...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc12-0428
更新日期:2013-05-01 00:00:00
abstract::To examine the clinical role of BAYm 1099, 15 diet-treated non-insulin-dependent diabetic (NIDDM) subjects were randomized to start drug (50 mg 3 times/day) or placebo after a 4-wk run-in period in a double-blind crossover study. Treatment periods (4 wk) were separated by a 2-wk washout period. During the last week of...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2337/diacare.11.4.337
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:We assessed the extent to which both standard and alternative indexes from 2-h oral glucose tolerance testing predict type 1 diabetes and whether oral glucose tolerance tests (OGTTs) predict type 1 diabetes in individuals with normal glucose tolerance. RESEARCH DESIGN AND METHODS:The prediction of type 1 dia...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究
doi:10.2337/dc06-1615
更新日期:2007-01-01 00:00:00