Prevalence of diabetes and ethnic differences in cardiovascular risk factors. The 1992 Singapore National Health Survey.

Abstract:

OBJECTIVE:The purpose of the 1992 Singapore National Health Survey was to determine the current distribution of major noncommunicable diseases and their risk factors, including the prevalence of diabetes and dyslipidemia, in Singapore. RESEARCH DESIGN AND METHODS:A combination of disproportionate stratified sampling and systematic sampling were used to select the sample for the survey. The final number of respondents was 3,568, giving a response rate of 72.6%. All subjects fasted for 10 h and were given a 75-g glucose load, except those known to have diabetes. Blood was taken before and 2 h after the glucose load. Diagnosis of diabetes was based on 2-h glucose alone. RESULTS:The age-standardized prevalence of diabetes in Singapore residents aged 18-69 years was 8.4%, with more than half (58.5%) previously undiagnosed. Prevalence of diabetes was high across all three ethnic groups. The prevalence of impaired glucose tolerance was 16.1%, that of hypertension was 6.5%, and 19.0% were regular smokers. The total cholesterol (mean +/- SD) of nondiabetic Singaporeans was 5.18 +/- 1.02 mmol/l; 47.9% had cholesterol > 5.2 mmol/l, while 15.4% had levels > 6.3 mmol/l. Mean LDL cholesterol was 3.31 +/- 0.89 mmol/l; HDL cholesterol was 1.30 +/- 0.32 mmol/l, and triglyceride was 1.23 +/- 0.82 mmol/l. CONCLUSIONS:Prevalence of diabetes was high across all three ethnic groups. Ethnic differences in prevalence of diabetes, insulin resistance, central obesity, hypertension, smoking, and lipid profile could explain the differential coronary heart disease rates in the three major ethnic groups in Singapore.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Tan CE,Emmanuel SC,Tan BY,Jacob E

doi

10.2337/diacare.22.2.241

subject

Has Abstract

pub_date

1999-02-01 00:00:00

pages

241-7

issue

2

eissn

0149-5992

issn

1935-5548

journal_volume

22

pub_type

杂志文章
  • No loss of chance of diabetic retinopathy screening by endocrinologists with a digital fundus camera.

    abstract:OBJECTIVE:To compare the efficacy of the diabetic retinopathy (DR) screening with digital camera by endocrinologists with that by specialist and resident ophthalmologists in terms of sensitivity, specificity, and level of "loss of chance." RESEARCH DESIGN AND METHODS:In a cross-sectional study, 500 adult diabetic pati...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-1373

    authors: Germain N,Galusca B,Deb-Joardar N,Millot L,Manoli P,Thuret G,Gain P,Estour B

    更新日期:2011-03-01 00:00:00

  • Day and Night Closed-Loop Control Using the Integrated Medtronic Hybrid Closed-Loop System in Type 1 Diabetes at Diabetes Camp.

    abstract:OBJECTIVE:To evaluate the feasibility and efficacy of a fully integrated hybrid closed-loop (HCL) system (Medtronic MiniMed Inc., Northridge, CA), in day and night closed-loop control in subjects with type 1 diabetes, both in an inpatient setting and during 6 days at diabetes camp. RESEARCH DESIGN AND METHODS:The Medt...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc14-3073

    authors: Ly TT,Roy A,Grosman B,Shin J,Campbell A,Monirabbasi S,Liang B,von Eyben R,Shanmugham S,Clinton P,Buckingham BA

    更新日期:2015-07-01 00:00:00

  • Reciprocal association of plasma IGF-1 and interleukin-6 levels with cardiometabolic risk factors in nondiabetic subjects.

    abstract:OBJECTIVE:To examine the relationship between plasma IGF-1 and interleukin-6 (IL-6) levels in Caucasian nondiabetic subjects and evaluate the association of IGF-1 and IL-6 with the cardiometabolic risk factors characterizing metabolic syndrome (MetS). RESEARCH DESIGN AND METHODS:The study group consisted of 186 Caucas...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-0553

    authors: Succurro E,Andreozzi F,Sciacqua A,Hribal ML,Perticone F,Sesti G

    更新日期:2008-09-01 00:00:00

  • Residual left ventricular pump function after acute myocardial infarction in NIDDM patients.

    abstract:OBJECTIVE:Left ventricular remodeling occurs immediately after MI, involving structural changes in noninfarcted segment. However, the residual left ventricular pump function in NIDDM patients after acute MI has not been clarified. The purpose of this study was to evaluate the difference in the process of left ventricul...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.15.11.1522

    authors: Iwasaka T,Takahashi N,Nakamura S,Sugiura T,Tarumi N,Kimura Y,Okubo N,Taniguchi H,Matsui Y,Inada M

    更新日期:1992-11-01 00:00:00

  • The effects of health beliefs on weight loss in individuals at high risk for NIDDM.

    abstract:OBJECTIVE:To determine whether perceived risk and other health beliefs held by individuals at high risk for developing NIDDM predict weight loss and behavior change during a behavioral weight loss program to reduce the risk of NIDDM. RESEARCH DESIGN AND METHODS:Health beliefs and objective risk factors for diabetes we...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.10.1533

    authors: Polley BA,Jakicic JM,Venditti EM,Barr S,Wing RR

    更新日期:1997-10-01 00:00:00

  • Altered postprandial insulin requirement in IDDM patients with gastroparesis.

    abstract:OBJECTIVE:To evaluate the effect of gastric emptying on postprandial insulin requirement in insulin-dependent diabetes mellitus (IDDM) patients with and without gastroparesis. RESEARCH DESIGN AND METHODS:Postprandial insulin requirement and gastric emptying were simultaneously evaluated in five IDDM patients with gast...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章

    doi:10.2337/diacare.17.8.901

    authors: Ishii M,Nakamura T,Kasai F,Onuma T,Baba T,Takebe K

    更新日期:1994-08-01 00:00:00

  • Exercise training improves vascular endothelial function in patients with type 1 diabetes.

    abstract::OBJECTIVE-Impaired endothelial function of resistance and conduit arteries can be detected in patients with type 1 diabetes. We studied whether a persistent improvement of endothelial function can be achieved by regular physical training. RESEARCH DESIGN AND METHODS-The study included 26 patients with type 1 diabetes ...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章

    doi:10.2337/diacare.25.10.1795

    authors: Fuchsjäger-Mayrl G,Pleiner J,Wiesinger GF,Sieder AE,Quittan M,Nuhr MJ,Francesconi C,Seit HP,Francesconi M,Schmetterer L,Wolzt M

    更新日期:2002-10-01 00:00:00

  • Association of Cardiometabolic Multimorbidity and Depression With Cardiovascular Events in Early-Onset Adult Type 2 Diabetes: A Multiethnic Study in the U.S.

    abstract:OBJECTIVE:To evaluate the temporal patterns of cardiometabolic multimorbidity (CM) and depression in White Caucasians (WCs) and African Americans (AAs) with early-onset type 2 diabetes and their impact on long-term atherosclerotic cardiovascular disease (ASCVD). RESEARCH DESIGN AND METHODS:From U.S. electronic medical...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc20-2045

    authors: Dibato JE,Montvida O,Zaccardi F,Sargeant JA,Davies MJ,Khunti K,Paul SK

    更新日期:2021-01-01 00:00:00

  • Distinct Patterns of Daily Glucose Variability by Pubertal Status in Youth With Type 1 Diabetes.

    abstract:OBJECTIVE:To evaluate glycemia and metrics of glucose variability in youth with type 1 diabetes, and to assess patterns of 24-h glucose variability according to pubertal status. RESEARCH DESIGN AND METHODS:Metrics of glycemia, glucose variability, and glucose patterns were assessed by using 4 weeks of continuous gluco...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-0083

    authors: Zhu J,Volkening LK,Laffel LM

    更新日期:2020-01-01 00:00:00

  • Diabetes and oral tumors in Hungary: epidemiological correlations.

    abstract:OBJECTIVE:Numerous publications have already demonstrated that diabetes is a risk factor for the development of periodontal diseases and various inflammatory lesions in the oral mucosa. A possible correlation between diabetes and oral premalignancies and tumors was examined in this study, as no literature data are avai...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.27.3.770

    authors: Ujpál M,Matos O,Bíbok G,Somogyi A,Szabó G,Suba Z

    更新日期:2004-03-01 00:00:00

  • Receiver operating characteristic analysis of HLA, CTLA4, and insulin genotypes for type 1 diabetes.

    abstract:OBJECTIVE:This study assessed the ability to distinguish between type 1 diabetes-affected individuals and their unaffected relatives using HLA and single nucleotide polymorphism (SNP) genotypes. RESEARCH DESIGN AND METHODS:Eight models, ranging from only the high-risk DR3/DR4 genotype to all significantly associated H...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc12-2284

    authors: Valdes AM,Varney MD,Erlich HA,Noble JA

    更新日期:2013-09-01 00:00:00

  • Biphasic insulin aspart 30/70: pharmacokinetics and pharmacodynamics compared with once-daily biphasic human insulin and Basal-bolus therapy.

    abstract::OBJECTIVE Pharmacological profiles of biphasic insulin aspart 30/70 (BIAsp 30) once daily (OD), twice daily (b.i.d.), and three times daily (t.i.d.) were compared with other insulin regimens in two crossover glucose clamp studies of insulin-treated type 2 diabetic patients. RESEARCH DESIGNS AND METHODS Study 1 consist...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-0097

    authors: Heise T,Heinemann L,Hövelmann U,Brauns B,Nosek L,Haahr HL,Olsen KJ

    更新日期:2009-08-01 00:00:00

  • Association of Blood Glucose Control and Lipids With Diabetic Retinopathy in the Veterans Affairs Diabetes Trial (VADT).

    abstract:OBJECTIVE:This study examined whether lipids modify the relationship between intensive glucose control (INT) and diabetic retinopathy (DR). RESEARCH DESIGN AND METHODS:The incidence and progression of DR were assessed in 858 of 1,791 participants with 7-field stereoscopic fundus photographs at baseline and 5 years lat...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc15-1897

    authors: Azad N,Bahn GD,Emanuele NV,Agrawal L,Ge L,Reda D,Klein R,Reaven PD,Hayward R,VADT Study Group.

    更新日期:2016-05-01 00:00:00

  • Postural instability in patients with diabetic sensory neuropathy.

    abstract:OBJECTIVE:Recent survey evidence suggests that sensory ataxia due to diabetic neuropathy may be a more frequent and serious problem than is commonly recognized. This view is further supported by research that confirms the major contribution of the somatosensory system to the control of posture. We therefore sought to d...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.17.12.1411

    authors: Simoneau GG,Ulbrecht JS,Derr JA,Becker MB,Cavanagh PR

    更新日期:1994-12-01 00:00:00

  • Beta-cell dysfunction, insulin sensitivity, and glycosuria precede diabetes in hepatocyte nuclear factor-1alpha mutation carriers.

    abstract:OBJECTIVE:Patients with diabetes due to hepatocyte nuclear factor (HNF)-1alpha mutations have beta-cell deficiency, insulin sensitivity, altered proinsulin levels, and a low renal threshold for glucose. It is uncertain how many of these features precede the development of diabetes. The aim of our study was to test for ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.28.7.1751

    authors: Stride A,Ellard S,Clark P,Shakespeare L,Salzmann M,Shepherd M,Hattersley AT

    更新日期:2005-07-01 00:00:00

  • The sulfonylurea glyburide induces impairment of glucagon and growth hormone responses during mild insulin-induced hypoglycemia.

    abstract:OBJECTIVE:The sulfonylurea (SU) glyburide may cause severe and prolonged episodes of hypoglycemia. We aimed at investigating the impact of glyburide on glucose counterregulatory hormones during stepwise hypoglycemic clamp studies. RESEARCH DESIGN AND METHODS:We performed stepwise hypoglycemic clamp studies in 16 healt...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.25.1.107

    authors: ter Braak EW,Appelman AM,van der Tweel I,Erkelens DW,van Haeften TW

    更新日期:2002-01-01 00:00:00

  • Moderate-intensity physical activity ameliorates the breast cancer risk in diabetic women.

    abstract:OBJECTIVE:To evaluate the association between self-reported diabetes and the risk of breast cancer (BC) and its interaction with moderate-intensity physical activity in pre- and postmenopausal Mexican women. RESEARCH DESIGN AND METHODS:A population-based case-control study was conducted using 1,000 incident case subje...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc11-2362

    authors: Torres-Mejía G,Angeles-Llerenas A,Ortega-Olvera C,Lazcano-Ponce E,Ziv E,Pulido-Rodríguez J,García-Solis Mde J,Murillo-Zamora E,Vázquez-Lara J,Romieu I

    更新日期:2012-12-01 00:00:00

  • Excess BMI Accelerates Islet Autoimmunity in Older Children and Adolescents.

    abstract:OBJECTIVE:Sustained excess BMI increases the risk of type 1 diabetes (T1D) in autoantibody-positive relatives without diabetes of patients. We tested whether elevated BMI also accelerates the progression of islet autoimmunity before T1D diagnosis. RESEARCH DESIGN AND METHODS:We studied 706 single autoantibody-positive...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-1167

    authors: Ferrara-Cook C,Geyer SM,Evans-Molina C,Libman IM,Becker DJ,Gitelman SE,Redondo MJ,Type 1 Diabetes TrialNet Study Group.

    更新日期:2020-03-01 00:00:00

  • Assessment of diabetic retinopathy using nonmydriatic ultra-widefield scanning laser ophthalmoscopy (Optomap) compared with ETDRS 7-field stereo photography.

    abstract:OBJECTIVE:To compare the diagnostic properties of a nonmydriatic 200° ultra-widefield scanning laser ophthalmoscope (SLO) versus mydriatic Early Treatment of Diabetic Retinopathy Study (ETDRS) 7-field photography for diabetic retinopathy (DR) screening. RESEARCH DESIGN AND METHODS:A consecutive series of 212 eyes of 1...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-0346

    authors: Kernt M,Hadi I,Pinter F,Seidensticker F,Hirneiss C,Haritoglou C,Kampik A,Ulbig MW,Neubauer AS

    更新日期:2012-12-01 00:00:00

  • Diabetes mellitus in Tohon O'odham pregnancies.

    abstract:OBJECTIVE:To determine the prevalence of diabetes in Tohono O'odham pregnancies, and to assess the efficacy of early prenatal diabetes screening in populations with high rates of diabetes. RESEARCH DESIGN AND METHODS:All Tohono O'odham women receiving prenatal care at the Sells Service Unit who delivered a viable baby...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.16.1.318

    authors: Livingston RC,Bachman-Carter K,Frank C,Mason WB

    更新日期:1993-01-01 00:00:00

  • Lipid testing among patients with diabetes who receive diabetes care from primary care physicians.

    abstract:OBJECTIVE:To identify factors related to lipid testing among patients with diabetes who receive diabetes care from primary care physicians. RESEARCH DESIGN AND METHODS:North Carolina Medicare claims were used to identify individuals with diabetes who received diabetes care from primary care physicians. Lipid testing w...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.26.5.1369

    authors: Massing MW,Henley NS,Carter-Edwards L,Schenck AP,Simpson RJ Jr

    更新日期:2003-05-01 00:00:00

  • Primary prevention of diabetes mellitus.

    abstract::Two-thirds of all deaths in developed countries are caused by the major noncommunicable diseases, e.g., cardiovascular disease, cancer, and non-insulin-dependent diabetes mellitus (NIDDM). There is increasing evidence that these diseases are a consequence of life-style change, and they have a number of risk factors in...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.11.3.258

    authors: Zimmet PZ

    更新日期:1988-03-01 00:00:00

  • Effect of rosiglitazone versus insulin on the pancreatic beta-cell function of subjects with type 2 diabetes.

    abstract:OBJECTIVE:In a previous study, we found observational evidence of improvement in beta-cell function when rosiglitazone was added to a failing oral antihyperglycemic regimen consisting of sulfonylureas and metformin. To confirm our previous observations, we designed and performed a prospective, randomized, and controlle...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.27.11.2585

    authors: Ovalle F,Bell DS

    更新日期:2004-11-01 00:00:00

  • Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes.

    abstract:OBJECTIVE:Maturity-onset diabetes of the young (MODY) due to variants in HNF1A is the most common type of monogenic diabetes. Frequent misdiagnosis results in missed opportunity to use sulfonylureas as first-line treatment. A nongenetic biomarker could improve selection of subjects for genetic testing and increase diag...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc18-0422

    authors: Juszczak A,Pavić T,Vučković F,Bennett AJ,Shah N,Pape Medvidović E,Groves CJ,Šekerija M,Chandler K,Burrows C,Rojnić Putarek N,Vučić Lovrenčić M,Ćuća Knežević J,James TJ,Gloyn AL,Lauc G,McCarthy MI,Owen KR,Gornik O

    更新日期:2019-01-01 00:00:00

  • American Diabetes Association's Fourth International Workshop-Conference on Gestational Diabetes Mellitus: summary and discussion. Therapeutic interventions.

    abstract::This review summarizes Session IV: Therapeutic Interventions of the Fourth International Gestational Diabetes Workshop and suggests intervention protocols based on the presentations at this meeting and the literature. The opinions of the six presenters and their interpretation of the review of the literature in their ...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:

    authors: Jovanovic L

    更新日期:1998-08-01 00:00:00

  • Diabetes in a Large Dementia Cohort: Clinical Characteristics and Treatment From the Swedish Dementia Registry.

    abstract:OBJECTIVE:We aimed to investigate the differences in clinical characteristics and pharmacological treatment associated with the presence of diabetes in a large cohort of patients with dementia. RESEARCH DESIGN AND METHODS:A cross-sectional registry-based study was conducted using data from the Swedish Dementia Registr...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc16-2516

    authors: Secnik J,Cermakova P,Fereshtehnejad SM,Dannberg P,Johnell K,Fastbom J,Winblad B,Eriksdotter M,Religa D

    更新日期:2017-09-01 00:00:00

  • Differences in the prevalence of diabetes and impaired glucose tolerance according to maternal or paternal history of diabetes.

    abstract:OBJECTIVE:To determine whether diabetes risk is influenced by which parent (a parental history of diabetes is a well-documented risk factor for NIDDM) is reported to have diabetes. RESEARCH DESIGN AND METHODS:We compared the prevalence of NIDDM and IGT for 4914 subjects according to their parental history of diabetes ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.16.9.1262

    authors: Mitchell BD,Valdez R,Hazuda HP,Haffner SM,Monterrosa A,Stern MP

    更新日期:1993-09-01 00:00:00

  • The midregional fragment of pro-A-type natriuretic peptide, blood pressure, and mortality in a prospective cohort study of patients with type 2 diabetes (ZODIAC-25).

    abstract:OBJECTIVE:Evidence that midregional fragment of pro-A-type natriuretic peptide (MR-proANP) is a marker of mortality in patients with type 2 diabetes is limited. Therefore, we aimed to investigate the capabilities of MR-proANP in predicting mortality. We also investigated whether MR-proANP influences the relationship be...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-0428

    authors: van Hateren KJ,Landman GW,Kleefstra N,Groenier KH,Struck J,Navis GJ,Bakker SJ,Houweling ST,van der Meer K,Bilo HJ

    更新日期:2013-05-01 00:00:00

  • Effects of BAYm 1099, new alpha-glucosidase inhibitor, on acute metabolic responses and metabolic control in NIDDM over 1 mo.

    abstract::To examine the clinical role of BAYm 1099, 15 diet-treated non-insulin-dependent diabetic (NIDDM) subjects were randomized to start drug (50 mg 3 times/day) or placebo after a 4-wk run-in period in a double-blind crossover study. Treatment periods (4 wk) were separated by a 2-wk washout period. During the last week of...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.11.4.337

    authors: Samad AH,Ty Willing TS,Alberti KG,Taylor R

    更新日期:1988-04-01 00:00:00

  • Increasing the accuracy of oral glucose tolerance testing and extending its application to individuals with normal glucose tolerance for the prediction of type 1 diabetes: the Diabetes Prevention Trial-Type 1.

    abstract:OBJECTIVE:We assessed the extent to which both standard and alternative indexes from 2-h oral glucose tolerance testing predict type 1 diabetes and whether oral glucose tolerance tests (OGTTs) predict type 1 diabetes in individuals with normal glucose tolerance. RESEARCH DESIGN AND METHODS:The prediction of type 1 dia...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/dc06-1615

    authors: Sosenko JM,Palmer JP,Greenbaum CJ,Mahon J,Cowie C,Krischer JP,Chase HP,White NH,Buckingham B,Herold KC,Cuthbertson D,Skyler JS,Diabetes Prevention Trial-Type 1 Study Group.

    更新日期:2007-01-01 00:00:00