Assessment of diabetic retinopathy using nonmydriatic ultra-widefield scanning laser ophthalmoscopy (Optomap) compared with ETDRS 7-field stereo photography.

Abstract:

OBJECTIVE:To compare the diagnostic properties of a nonmydriatic 200° ultra-widefield scanning laser ophthalmoscope (SLO) versus mydriatic Early Treatment of Diabetic Retinopathy Study (ETDRS) 7-field photography for diabetic retinopathy (DR) screening. RESEARCH DESIGN AND METHODS:A consecutive series of 212 eyes of 141 patients with different levels of DR were examined. Grading of DR and clinically significant macular edema (CSME) from mydriatic ETDRS 7-field stereo photography was compared with grading obtained by Optomap Panoramic 200 SLO images. All SLO scans were performed through an undilated pupil, and no additional clinical information was used for evaluation of all images by the two independent, masked, expert graders. RESULTS:Twenty-two eyes from ETDRS 7-field photography and 12 eyes from Optomap were not gradable by at least one grader because of poor image quality. A total of 144 eyes were analyzed regarding DR level and 155 eyes regarding CSME. For ETDRS 7-field photography, 22 eyes (18 for grader 2) had no or mild DR (ETDRS levels ≤ 20) and 117 eyes (111 for grader 2) had no CSME. A highly substantial agreement between both Optomap DR and CSME grading and ETDRS 7-field photography existed with κ = 0.79 for DR and 0.73 for CSME for grader 1, and κ = 0.77 (DR) and 0.77 (CSME) for grader 2. CONCLUSIONS:Determination of CSME and grading of DR level from Optomap Panoramic 200 nonmydriatic images show a positive correlation with mydriatic ETDRS 7-field stereo photography. Both techniques are of sufficient quality to assess DR and CSME. Optomap Panoramic 200 images cover a larger retinal area and therefore may offer additional diagnostic properties.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Kernt M,Hadi I,Pinter F,Seidensticker F,Hirneiss C,Haritoglou C,Kampik A,Ulbig MW,Neubauer AS

doi

10.2337/dc12-0346

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

2459-63

issue

12

eissn

0149-5992

issn

1935-5548

pii

dc12-0346

journal_volume

35

pub_type

杂志文章
  • Sex hormone-binding globulin levels predict insulin sensitivity, disposition index, and cardiovascular risk during puberty.

    abstract:OBJECTIVE:Early puberty is associated with increased risk of subsequent cardiovascular disease. Low sex hormone-binding globulin (SHBG) levels are a feature of early puberty and of conditions associated with increased cardiovascular risk. The aim of the present study was to evaluate SHBG as a predictor of glucose metab...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-1618

    authors: Sørensen K,Aksglaede L,Munch-Andersen T,Aachmann-Andersen NJ,Petersen JH,Hilsted L,Helge JW,Juul A

    更新日期:2009-05-01 00:00:00

  • Influence of time of day of blood pressure-lowering treatment on cardiovascular risk in hypertensive patients with type 2 diabetes.

    abstract:OBJECTIVE:We prospectively investigated in hypertensive patients with type 2 diabetes if bedtime treatment with ≥1 hypertension medications exerts better blood pressure control and cardiovascular risk reduction than conventional therapy, in which all medications are ingested in the morning. RESEARCH DESIGN AND METHODS...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc11-0297

    authors: Hermida RC,Ayala DE,Mojón A,Fernández JR

    更新日期:2011-06-01 00:00:00

  • Glucosuria in children with diabetes: advantages of the 2-drop Clinitest method.

    abstract::In order to assess the actual and theoretical limitations of using the traditional urinary glucose determinations as an indicator of plasma glucose concentration, we have measured plasma and urine glucose concentrations in 37 children with diabetes mellitus. A constant blood withdrawal system enabled an accurate estim...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.2.4.349

    authors: Winter RJ,Traisman HS,Green OC

    更新日期:1979-07-01 00:00:00

  • Lactation Duration and Long-term Risk for Incident Type 2 Diabetes in Women With a History of Gestational Diabetes Mellitus.

    abstract:OBJECTIVE:We examined the association of lactation duration with incident type 2 diabetes among women with a history of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:We monitored 4,372 women with a history of GDM participating in the Nurses' Health Study II for incident type 2 diabetes over 25 years...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-2237

    authors: Ley SH,Chavarro JE,Li M,Bao W,Hinkle SN,Wander PL,Rich-Edwards J,Olsen S,Vaag A,Damm P,Grunnet LG,Mills JL,Hu FB,Zhang C

    更新日期:2020-04-01 00:00:00

  • Use of tactile techniques for self-monitoring of blood glucose in visually impaired patients with diabetes mellitus.

    abstract::Twenty-eight patients with type I diabetes mellitus, legally blind as a result of proliferative retinopathy, were recruited into a program designed to teach and evaluate tactile methods for self-monitoring of blood glucose (SMBG). Vision ranged from "blind" to "able to read large print." Techniques with wipe-off strip...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.7.4.313

    authors: Prior JC,Alojado NC,Hunt JA,Begg IS

    更新日期:1984-07-01 00:00:00

  • Randomized prospective trial of pure porcine and conventional bovine/porcine insulin.

    abstract::Use of pure porcine insulin versus partially purified insulin of bovine/porcine origin might be expected to have certain clinical benefits, e.g., a lower incidence of skin reactions, a lower insulin dosage, better diabetes regulation, and greater preservation of endogenous insulin secretion. To test this hypothesis, w...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.10.3.337

    authors: Asplin C,Raghu P,Clemons P,Lyen K,Tatpati O,McKnight B,Baker L,Guthrie R,Sperling M,Palmer J

    更新日期:1987-05-01 00:00:00

  • Fish oil and glycemic control in diabetes. A meta-analysis.

    abstract:OBJECTIVE:Hypertriglyceridemia is associated with cardiovascular disease in diabetes. Fibrates effectively lower, but do not always normalize, serum triglyceride levels. Fish oil supplements may then be added to lower serum triglyceride levels. Doubt remains whether the net effect of fish oil intake on glycemic control...

    journal_title:Diabetes care

    pub_type: 杂志文章,meta分析

    doi:10.2337/diacare.21.4.494

    authors: Friedberg CE,Janssen MJ,Heine RJ,Grobbee DE

    更新日期:1998-04-01 00:00:00

  • The Impact of Glycated Hemoglobin (HbA1c) on Cardiovascular Disease Risk: A Mendelian Randomization Study Using UK Biobank.

    abstract:OBJECTIVE:Glycated hemoglobin (HbA1c) is positively associated with cardiovascular disease (CVD), although evidence is primarily observational. Mendelian randomization studies have only examined its relation with subtypes of CVD. We examined the relation of HbA1c with CVD and its subtypes in the UK Biobank using Mendel...

    journal_title:Diabetes care

    pub_type: 杂志文章,meta分析

    doi:10.2337/dc18-0289

    authors: Au Yeung SL,Luo S,Schooling CM

    更新日期:2018-09-01 00:00:00

  • Expression of matrix metalloproteinases, cytokines, and connexins in diabetic and nondiabetic human keratinocytes before and after transplantation into an ex vivo wound-healing model.

    abstract:OBJECTIVE:Wound healing is known to require a well-organized balance of numerous factors, e.g., cytokines, matrix metalloproteinases (MMPs), and their inhibitors, as well as direct cell-cell communication (connexins). Disruption of this balance may lead to the formation of chronic wounds such as diabetic foot ulcers. T...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc07-1304

    authors: Brandner JM,Zacheja S,Houdek P,Moll I,Lobmann R

    更新日期:2008-01-01 00:00:00

  • Relationship of insulin resistance and related metabolic variables to coronary artery disease: a mathematical analysis.

    abstract:OBJECTIVE:People with diabetes have an increased risk of coronary artery disease (CAD). An unanswered question is what portion of CAD can be attributed to insulin resistance, related metabolic variables, and other known CAD risk factors. RESEARCH DESIGN AND METHODS:The Archimedes model was used to estimate the proport...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-0854

    authors: Eddy D,Schlessinger L,Kahn R,Peskin B,Schiebinger R

    更新日期:2009-02-01 00:00:00

  • Determinants of incident hyperglycemia 6 years after delivery in young rural Indian mothers: the Pune Maternal Nutrition Study (PMNS).

    abstract:OBJECTIVE:To study determinants of incident hyperglycemia in rural Indian mothers 6 years after delivery. RESEARCH DESIGN AND METHODS:The Pune Maternal Nutrition Study collected information in six villages near Pune on prepregnant characteristics and nutrition, physical activity, and glucose tolerance during pregnancy...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc07-0329

    authors: Kulkarni SR,Fall CH,Joshi NV,Lubree HG,Deshpande VU,Pasarkar RV,Bhat DS,Naik SS,Yajnik CS

    更新日期:2007-10-01 00:00:00

  • The dynamics of diabetes among birth cohorts in the U.S.

    abstract::OBJECTIVE Using a nationally representative sample of the civilian noninstitutionalized U.S. population, we estimated trends in diabetes prevalence across cohorts born 1910-1989 and provide the first estimates of age-specific diabetes incidence using nationally representative, measured data. RESEARCH DESIGN AND METHOD...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc13-1982

    authors: Fishman EI,Stokes A,Preston SH

    更新日期:2014-04-01 00:00:00

  • Nonremovable, windowed, fiberglass cast boot in the treatment of diabetic plantar ulcers: efficacy, safety, and compliance.

    abstract:OBJECTIVE:To compare the efficacy, safety, and compliance of a nonremovable fiberglass cast boot and off-loading shoes in the treatment of diabetic plantar ulcers. RESEARCH DESIGN AND METHODS:Patients (n = 93) with noninfected, nonischemic plantar ulcers were included in this prospective nonrandomized study. Treatment...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章

    doi:10.2337/diacare.26.10.2848

    authors: Ha Van G,Siney H,Hartmann-Heurtier A,Jacqueminet S,Greau F,Grimaldi A

    更新日期:2003-10-01 00:00:00

  • Diabetic Neuropathy Is a Substantial Burden in People With Type 1 Diabetes and Is Strongly Associated With Socioeconomic Disadvantage: A Population-Representative Study From Scotland.

    abstract:OBJECTIVE:To assess the contemporaneous prevalence of diabetic peripheral neuropathy (DPN) in people with type 1 diabetes (T1D) in Scotland and study its cross-sectional association with risk factors and other diabetic complications. RESEARCH DESIGN AND METHODS:We analyzed data from a large representative sample of ad...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-1582

    authors: Jeyam A,McGurnaghan SJ,Blackbourn LAK,McKnight JM,Green F,Collier A,McKeigue PM,Colhoun HM,SDRNT1BIO Investigators.

    更新日期:2020-04-01 00:00:00

  • Urinary C-peptide as a measure of beta-cell function after a mixed meal in healthy subjects: comparison of four-hour urine C-peptide with serum insulin and plasma C-peptide.

    abstract::Urinary C-peptide (UCP) is a noninvasive measure of integrated insulin production, and the usefulness of 24-h collections has been previously reported. Only small numbers of subjects have been studied using shorter urine collections. To see how well 4-h urine collections for C-peptide (UCP) correlate with serum immuno...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.6.5.488

    authors: Hoogwerf BJ,Barbosa JJ,Bantle JP,Laine D,Goetz FC

    更新日期:1983-09-01 00:00:00

  • Family functioning and metabolic control of school-aged children with IDDM.

    abstract::The relationship of two aspects of family life to metabolic control were examined as part of a longitudinal study of school-aged children with newly diagnosed insulin-dependent diabetes mellitus (IDDM). Glycosylated hemoglobin level was the primary index of metabolic control; weight-adjusted insulin dosage served as a...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.12.6.409

    authors: Kovacs M,Kass RE,Schnell TM,Goldston D,Marsh J

    更新日期:1989-06-01 00:00:00

  • GLP-1 tablet in type 2 diabetes in fasting and postprandial conditions.

    abstract:OBJECTIVE:To examine the absorption of glucagon-like peptide (GLP)-1(7-36) amide from the buccal mucosa of type 2 diabetic patients. Previously, the effects of the peptide have been studied following intravenous and subcutaneous injection. Now, a mucoadhesive, biodegradable buccal GLP-1 tablet (9 mm) containing 119 nmo...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.20.12.1874

    authors: Gutniak MK,Larsson H,Sanders SW,Juneskans O,Holst JJ,Ahrén B

    更新日期:1997-12-01 00:00:00

  • Genetics and the prediction of complications in type 1 diabetes.

    abstract:OBJECTIVE:Epidemiological evidence suggests that genetic factors can affect the course of type 1 diabetes complications produced by long-lasting hyperglycemia. In this review, the current strategies applicable to identifying these genetic factors are examined, as are recent findings on the genetics of diabetic nephropa...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:

    authors: Marre M

    更新日期:1999-03-01 00:00:00

  • Diastolic dysfunction in normotensive men with well-controlled type 2 diabetes: importance of maneuvers in echocardiographic screening for preclinical diabetic cardiomyopathy.

    abstract:OBJECTIVE:Because a pseudonormal pattern of ventricular filling has never been considered in studies that reported a prevalence of left ventricular diastolic dysfunction (LVDD) between 20 and 40%, our aim was to more completely evaluate the prevalence of LVDD in subjects with diabetes. RESEARCH DESIGN AND METHODS:We s...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.24.1.5

    authors: Poirier P,Bogaty P,Garneau C,Marois L,Dumesnil JG

    更新日期:2001-01-01 00:00:00

  • Is "sugar" the same as diabetes? A community-based study among rural African-Americans.

    abstract:OBJECTIVE:To determine if differing beliefs about high blood glucose exist and are associated with blood glucose control among rural African-Americans. RESEARCH DESIGN AND METHODS:A community-based sample of rural African-Americans completed a survey, and a subsample underwent a subsequent screening that included gluc...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.23.3.330

    authors: Schorling JB,Saunders JT

    更新日期:2000-03-01 00:00:00

  • Diabetes mellitus and its vascular complications in Japanese migrants on the Island of Hawaii.

    abstract::Japanese migrants and their offspring on the island of Hawaii and Japanese living in Hiroshima were examined for diabetes mellitus and its vascular complications. the same methods and investigators were used in both locations. Death certificates of Japanese and Caucasians dying on the island during the past 26 yr were...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.2.2.161

    authors: Kawate R,Yamakido M,Nishimoto Y,Bennett PH,Hamman RF,Knowler WC

    更新日期:1979-03-01 00:00:00

  • Clinical trials of cyclosporin in IDDM.

    abstract::The results of uncontrolled trials in immunomodulation of insulin-dependent diabetes mellitus (IDDM) led to randomized controlled trials in Canada and Europe. In the Canadian open study, the rate of clinical remissions (target control of glycemia maintained with less than or equal to 0.15 U.kg-1.day-1 insulin) was une...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章

    doi:

    authors: Dupré J,Stiller CR,Gent M,Donner A,von Graffenried B,Heinrichs D,Jenner M,Keown P,Mahon J,Martell R

    更新日期:1988-11-01 00:00:00

  • Excess BMI in Childhood: A Modifiable Risk Factor for Type 1 Diabetes Development?

    abstract:OBJECTIVE:We aimed to determine the effect of elevated BMI over time on the progression to type 1 diabetes in youth. RESEARCH DESIGN AND METHODS:We studied 1,117 children in the TrialNet Pathway to Prevention cohort (autoantibody-positive relatives of patients with type 1 diabetes). Longitudinally accumulated BMI abov...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc16-2331

    authors: Ferrara CT,Geyer SM,Liu YF,Evans-Molina C,Libman IM,Besser R,Becker DJ,Rodriguez H,Moran A,Gitelman SE,Redondo MJ,Type 1 Diabetes TrialNet Study Group.

    更新日期:2017-05-01 00:00:00

  • Diabetes in a Large Dementia Cohort: Clinical Characteristics and Treatment From the Swedish Dementia Registry.

    abstract:OBJECTIVE:We aimed to investigate the differences in clinical characteristics and pharmacological treatment associated with the presence of diabetes in a large cohort of patients with dementia. RESEARCH DESIGN AND METHODS:A cross-sectional registry-based study was conducted using data from the Swedish Dementia Registr...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc16-2516

    authors: Secnik J,Cermakova P,Fereshtehnejad SM,Dannberg P,Johnell K,Fastbom J,Winblad B,Eriksdotter M,Religa D

    更新日期:2017-09-01 00:00:00

  • Replacement of Red and Processed Meat With Other Food Sources of Protein and the Risk of Type 2 Diabetes in European Populations: The EPIC-InterAct Study.

    abstract:OBJECTIVE:There is sparse evidence for the association of suitable food substitutions for red and processed meat on the risk of type 2 diabetes. We modeled the association between replacing red and processed meat with other protein sources and the risk of type 2 diabetes and estimated its population impact. RESEARCH D...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc20-1038

    authors: Ibsen DB,Steur M,Imamura F,Overvad K,Schulze MB,Bendinelli B,Guevara M,Agudo A,Amiano P,Aune D,Barricarte A,Ericson U,Fagherazzi G,Franks PW,Freisling H,Quiros JR,Grioni S,Heath AK,Huybrechts I,Katze V,Laouali N,

    更新日期:2020-11-01 00:00:00

  • Diabetes complications and mortality among Alaska Natives: 8 years of observation.

    abstract:OBJECTIVE:To determine the prevalence and incidence of diabetes in Alaska Natives and the incidence of cerebrovascular accidents (stroke), myocardial infarction (MI), end-stage renal disease (ESRD), lower-extremity amputations (LEA), and mortality over a 6- to 8-year period. RESEARCH DESIGN AND METHODS:The data derive...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.3.314

    authors: Schraer CD,Adler AI,Mayer AM,Halderson KR,Trimble BA

    更新日期:1997-03-01 00:00:00

  • Elevation of N-(carboxymethyl)valine residue in hemoglobin of diabetic patients. Its role in the development of diabetic nephropathy.

    abstract:OBJECTIVE:Advanced glycation end products (AGEs) are a risk factor for diabetic complications. We have developed an assay method for N-(carboxymethyl)valine (CMV) of the hemoglobin (CMV-Hb), which is an AGE generated from HbA1c. Herein we describe the clinical utility of CMV-Hb measurement for the diagnosis of diabetic...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.24.5.891

    authors: Uchimura T,Nakano K,Hashiguchi T,Iwamoto H,Miura K,Yoshimura Y,Hanyu N,Hirata K,Imakuma M,Motomiya Y,Maruyama I

    更新日期:2001-05-01 00:00:00

  • Smoking and mortality among women with type 2 diabetes: The Nurses' Health Study cohort.

    abstract:OBJECTIVE:To assess the relationship between cigarette smoking and mortality among women with type 2 diabetes in the Nurses' Health Study cohort. RESEARCH DESIGN AND METHODS:The Nurses' Health Study, a prospective cohort of U.S. female registered nurses, included 7,401 women with type 2 diabetes diagnosed at baseline ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.24.12.2043

    authors: Al-Delaimy WK,Willett WC,Manson JE,Speizer FE,Hu FB

    更新日期:2001-12-01 00:00:00

  • Accuracy and Longevity of an Implantable Continuous Glucose Sensor in the PRECISE Study: A 180-Day, Prospective, Multicenter, Pivotal Trial.

    abstract:OBJECTIVE:It is known that continuous glucose monitoring (CGM) systems can lower mean glucose compared with episodic self-monitoring of blood glucose. Implantable CGM systems may provide additional benefits. RESEARCH DESIGN AND METHODS:We studied the Eversense (Senseonics Inc.) implantable CGM sensor in 71 participant...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.2337/dc16-1525

    authors: Kropff J,Choudhary P,Neupane S,Barnard K,Bain SC,Kapitza C,Forst T,Link M,Dehennis A,DeVries JH

    更新日期:2017-01-01 00:00:00

  • Cerebral and ophthalmic artery hemodynamic responses in diabetes mellitus.

    abstract:OBJECTIVE:To address whether hemodynamic responses in the cerebral arteries and OAs may be altered in patients with diabetic retinopathy. We used TCD to evaluate the effects of changes in BP, posture, and exercise on MCA and OA blood flow velocities. RESEARCH DESIGN AND METHODS:We evaluated 13 patients with BDR, 19 wi...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.16.2.476

    authors: Albert SG,Gomez CR,Russell S,Chaitman BR,Bernbaum M,Kong BA

    更新日期:1993-02-01 00:00:00