Translating lifestyle intervention to practice in obese patients with type 2 diabetes: Improving Control with Activity and Nutrition (ICAN) study.

Abstract:

OBJECTIVE:To assess the efficacy of a lifestyle intervention program that can be readily translated into clinical practice for obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:The study consisted of a 12-month randomized controlled trial of 147 health plan members with type 2 diabetes and obesity (BMI >or=27 kg/m(2)). Participants were randomized to lifestyle case management or usual care. Case management entailed individual and group education, support, and referral by registered dietitians; intervention cost was US dollars 350 per person. Individuals treated with usual care received educational material. Both groups received ongoing primary care. Outcomes were difference between groups for change in weight (kilograms), waist circumference (centimeters), HbA(1c), fasting lipid levels, use of prescription medications, and health-related quality of life. RESULTS:Case management resulted in greater weight loss (P < 0.001), reduced waist circumference (P < 0.001), reduced HbA(1c) level (P = 0.02), less use of prescription medications (P = 0.03), and improved health-related quality of life (P < 0.001) compared with usual care. The 12-month group difference in weight loss and waist circumference was 3.0 kg (95% CI -5.4 to -0.6) and -4.2 cm (-6.8 to -1.6). HbA(1c) differences were greatest at 4 months (-0.59%, P = 0.006) but not significant by 12 months (-0.19%, P = 0.45). Participants in the case management group lowered their use of medications, primarily diabetes medications, by 0.8 medications per day more than participants treated with usual care (P = 0.03). In seven of nine quality-of-life domains, the case management group improved compared with usual care (P < 0.05). CONCLUSIONS:Moderate-cost dietitian-led lifestyle case management may improve diverse health indicators among obese patients with type 2 diabetes.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Wolf AM,Conaway MR,Crowther JQ,Hazen KY,L Nadler J,Oneida B,Bovbjerg VE,Improving Control with Activity and Nutrition (ICAN) Study.

doi

10.2337/diacare.27.7.1570

subject

Has Abstract

pub_date

2004-07-01 00:00:00

pages

1570-6

issue

7

eissn

0149-5992

issn

1935-5548

pii

27/7/1570

journal_volume

27

pub_type

临床试验,杂志文章,随机对照试验
  • The long-term effects of chlorpropamide on insulin, C-peptide, and proinsulin secretion.

    abstract::It had been suggested that long-term lowering of blood glucose by sulfonylureas in non-insulin-dependent (NIDD) diabetes is not due to a sustained increase in insulin secretion. We have re-examined this question. Thirteen nonobese NIDD patients not controlled on diet alone were studied prospectively on treatment with ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.5.4.427

    authors: Elkeles RS,Heding LG,Paisey RB

    更新日期:1982-07-01 00:00:00

  • Comparison of Visidex and Chemstrip bG with Beckman Glucose Analyzer determination of blood glucose.

    abstract::Chemical test strips for estimating blood glucose have been shown to be reliable, rapid, and convenient when properly used. This study compares a new product, the Ames Visidex (Miles Laboratories, Elkhart, Indiana), and an established product, the Bio-Dynamics Chemstrip bG (Boehringer-Mannheim, Indianapolis, Indiana) ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.6.6.536

    authors: Frindik JP,Kassner DA,Pirkle DA,Kemp SF,Hoff C

    更新日期:1983-11-01 00:00:00

  • The prevalence of diabetes in a Swedish population of 280,411 inhabitants. A report from the Skaraborg Diabetes Registry.

    abstract:OBJECTIVE:To estimate the prevalence of known diabetes in a Swedish county (Skaraborg) and to evaluate capture-recapture methods for validation of the diabetes prevalence. RESEARCH DESIGN AND METHODS:Four sources were used to find known diabetic patients: 1) the Skaraborg Diabetes Registry (SDR), a case-finding invent...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.21.4.546

    authors: Berger B,Stenström G,Chang YF,Sundkvist G

    更新日期:1998-04-01 00:00:00

  • Health Care Utilization and Burden of Diabetic Ketoacidosis in the U.S. Over the Past Decade: A Nationwide Analysis.

    abstract:OBJECTIVE:Diabetes is one of the most common chronic diseases and a leading cause of morbidity and mortality in the U.S. Although our ability to treat diabetes and its associated complications has significantly improved, presentation with uncontrolled diabetes leading to ketoacidosis remains a significant problem. RES...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc17-1379

    authors: Desai D,Mehta D,Mathias P,Menon G,Schubart UK

    更新日期:2018-08-01 00:00:00

  • Differences in the prevalence of diabetes and impaired glucose tolerance according to maternal or paternal history of diabetes.

    abstract:OBJECTIVE:To determine whether diabetes risk is influenced by which parent (a parental history of diabetes is a well-documented risk factor for NIDDM) is reported to have diabetes. RESEARCH DESIGN AND METHODS:We compared the prevalence of NIDDM and IGT for 4914 subjects according to their parental history of diabetes ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.16.9.1262

    authors: Mitchell BD,Valdez R,Hazuda HP,Haffner SM,Monterrosa A,Stern MP

    更新日期:1993-09-01 00:00:00

  • Diabetes care in health maintenance organizations.

    abstract::An increasing amount of health care today is directed to the amelioration of chronic diseases for which there are no cures. Technological advances and the aging of the population have increased the costs of that care. In an attempt to control costs and increase the efficiency of health care, it is being increasingly d...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:10.2337/diacare.15.1.s44

    authors: Geffner DL

    更新日期:1992-03-01 00:00:00

  • Ethnic and racial differences in diabetes care: The Insulin Resistance Atherosclerosis Study.

    abstract:OBJECTIVE:Diabetes and its complications disproportionately affect African Americans and Hispanics. Complications could be prevented with appropriate medical care. We compared five processes of care and three outcomes of care among African Americans, Hispanics, and non-Hispanic whites. RESEARCH DESIGN AND METHODS:We u...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/diacare.26.4.1040

    authors: Bonds DE,Zaccaro DJ,Karter AJ,Selby JV,Saad M,Goff DC Jr

    更新日期:2003-04-01 00:00:00

  • Acquired Generalized Lipodystrophy: A New Cause of Anti-PD-1 Immune-Related Diabetes.

    abstract:OBJECTIVE:Anti-programmed cell death-1 (anti-PD-1) antibodies have revolutionized advanced cancer therapy. Anti-PD-1 therapy is responsible for immune-related adverse events, with frequent endocrine manifestations, including acute-onset type 1 diabetes. Acquired generalized lipodystrophy (AGL) is a rare disease, believ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc18-2535

    authors: Jehl A,Cugnet-Anceau C,Vigouroux C,Legeay AL,Dalle S,Harou O,Marchand L,Lascols O,Caussy C,Thivolet C,Laville M,Disse E

    更新日期:2019-10-01 00:00:00

  • Treatment with the human once-weekly glucagon-like peptide-1 analog taspoglutide in combination with metformin improves glycemic control and lowers body weight in patients with type 2 diabetes inadequately controlled with metformin alone: a double-blind p

    abstract:OBJECTIVE:To evaluate the efficacy and safety of taspoglutide (R1583/BIM51077), a human once-weekly glucagon-like peptide-1 analog, in patients with type 2 diabetes inadequately controlled with metformin. RESEARCH DESIGN AND METHODS:Type 2 diabetic (n = 306) patients who failed to obtain glycemic control (A1C 7-9.5%) ...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc08-1961

    authors: Nauck MA,Ratner RE,Kapitza C,Berria R,Boldrin M,Balena R

    更新日期:2009-07-01 00:00:00

  • Lifestyle intervention for prevention of type 2 diabetes in primary health care: one-year follow-up of the Finnish National Diabetes Prevention Program (FIN-D2D).

    abstract:OBJECTIVE:To investigate 1-year outcomes of a national diabetes prevention program in Finland. RESEARCH DESIGN AND METHODS:Altogether 10,149 individuals at high risk for diabetes were identified with the Finnish Diabetes Risk Score (FINDRISC; scoring ≥15 points), by a history of impaired fasting glucose (IFG) or impai...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-0410

    authors: Saaristo T,Moilanen L,Korpi-Hyövälti E,Vanhala M,Saltevo J,Niskanen L,Jokelainen J,Peltonen M,Oksa H,Tuomilehto J,Uusitupa M,Keinänen-Kiukaanniemi S

    更新日期:2010-10-01 00:00:00

  • Predictors of Quality of Life and Other Patient-Reported Outcomes in the PANORAMA Multinational Study of People With Type 2 Diabetes.

    abstract:OBJECTIVE:PANORAMA, a nine-country cross-sectional type 2 diabetes study, investigated factors associated with quality of life (QoL), health status, and other patient-reported outcome measures (PROMs). RESEARCH DESIGN AND METHODS:Patients were randomly or consecutively selected from primary/secondary care. PROMs inclu...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/dc16-2655

    authors: Bradley C,Eschwège E,de Pablos-Velasco P,Parhofer KG,Simon D,Vandenberghe H,Gönder-Frederick L

    更新日期:2018-02-01 00:00:00

  • Dyslipidemias among normoglycemic members of familial NIDDM pedigrees.

    abstract:OBJECTIVE:To examine the hypothesis that hyperinsulinemia among relatives of NIDDM probands will increase the prevalence of DLPs, we measured insulin levels and examined the frequency of DLPs among NIDDM pedigree members. RESEARCH DESIGN AND METHODS:We performed 2-h 75-g OGTTs and measured lipid and insulin levels of ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.15.10.1285

    authors: Schumacher MC,Maxwell TM,Wu LL,Hunt SC,Williams RR,Elbein SC

    更新日期:1992-10-01 00:00:00

  • Severe hypoglycemia and cognitive decline in older people with type 2 diabetes: the Edinburgh type 2 diabetes study.

    abstract:OBJECTIVE:People with type 2 diabetes are at increased risk of age-related cognitive decline and dementia. Hypoglycemia is a candidate risk factor, but the direction of association between episodes of severe hypoglycemia and cognitive decline in type 2 diabetes remains uncertain. RESEARCH DESIGN AND METHODS:In the Edi...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc13-1384

    authors: Feinkohl I,Aung PP,Keller M,Robertson CM,Morling JR,McLachlan S,Deary IJ,Frier BM,Strachan MW,Price JF,Edinburgh Type 2 Diabetes Study (ET2DS) Investigators.

    更新日期:2014-02-01 00:00:00

  • Self-monitored blood glucose: the essential biofeedback signal in the diabetic patient's effort to achieve normoglycemia.

    abstract::Seventeen pregnant diabetic women participated in a special outpatient program during which they learned to self-monitor blood glucose (BG) and to vary insulin dosage on the basis of the results. The Ames Eyetone reflectance meter and the Boehringer Reflomat were used for BG analysis. BG was self-monitored at least tw...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.3.1.163

    authors: Irsigler K,Bali-Taubald C

    更新日期:1980-01-01 00:00:00

  • Changes in triglyceride levels over time and risk of type 2 diabetes in young men.

    abstract:OBJECTIVE:The association between changes in triglyceride concentrations over time and diabetes is unknown. We assessed whether two triglyceride determinations obtained 5 years apart can predict incident type 2 diabetes. RESEARCH DESIGN AND METHODS:Triglyceride levels at baseline (time 1) and 5 years later (time 2), f...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-0825

    authors: Tirosh A,Shai I,Bitzur R,Kochba I,Tekes-Manova D,Israeli E,Shochat T,Rudich A

    更新日期:2008-10-01 00:00:00

  • Alcohol and the NIDDM patient.

    abstract::Historically, alcohol use by the diabetic patient has been controversial. Recent studies in the general population have shown an improvement in mortality with moderate alcohol intake (one to three drinks per day). This improved mortality is greatest in those individuals who have a higher risk of ischemic heart disease...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:10.2337/diacare.19.5.509

    authors: Bell DS

    更新日期:1996-05-01 00:00:00

  • Asymptomatic bacteriuria and hemoglobin A1.

    abstract::We measured hemoglobin A1 (HbA1) and performed clean-catch urine cultures in 752 patients (411 men and 341 women) with non-insulin-dependent diabetes mellitus (NIDDM) attending an outpatient diabetes clinic. Prevalence of bacteriuria was significantly greater in diabetic women than in controls (9.1 vs. 5.0%, P less th...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.9.5.518

    authors: Schmitt JK,Fawcett CJ,Gullickson G

    更新日期:1986-09-01 00:00:00

  • Diabetes nutrition and complications trial (DNCT): food intake and targets of diabetes treatment in a sample of Spanish people with diabetes. Diabetes and Nutrition Study Group of the Spanish Diabetes Association (GSEDNu).

    abstract:OBJECTIVE:To know the nutritional pattern of people with diabetes in Spain and that pattern's relationship with targets of metabolic control. RESEARCH DESIGN AND METHODS:The Diabetes Nutrition and Complications Trial (DNCT) is a prospective multicenter study designed to determine the nutritional behavior of diabetic p...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/diacare.20.7.1078

    authors:

    更新日期:1997-07-01 00:00:00

  • Life years lost and lifetime health care expenditures associated with diabetes in the U.S., National Health Interview Survey, 1997-2000.

    abstract:OBJECTIVE:This study analyzed the lifetime health care expenditures and life years lost associated with diabetes in the U.S. RESEARCH DESIGN AND METHODS:Data from the National Health Interview Survey (NHIS), the Medical Expenditure Panel Survey from 1997 to 2000, and the NHIS Linked Mortality Public-use Files with a m...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc14-1453

    authors: Leung MY,Pollack LM,Colditz GA,Chang SH

    更新日期:2015-03-01 00:00:00

  • Racial/ethnic disparities in the prevalence of gestational diabetes mellitus by BMI.

    abstract:OBJECTIVE:To examine whether the association between gestational diabetes mellitus (GDM) and BMI category varies by racial/ethnic group. RESEARCH DESIGN AND METHODS:In a cohort of 123,040 women without recognized pregravid diabetes who delivered babies between 1995 and 2006 at Kaiser Permanente of Northern California,...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc11-2267

    authors: Hedderson M,Ehrlich S,Sridhar S,Darbinian J,Moore S,Ferrara A

    更新日期:2012-07-01 00:00:00

  • Role of common sequence variants in insulin secretion in familial type 2 diabetic kindreds: the sulfonylurea receptor, glucokinase, and hepatocyte nuclear factor 1alpha genes.

    abstract:OBJECTIVE:We have demonstrated high heritability of insulin secretion measured as acute insulin response to glucose times insulin sensitivity (disposition index). Furthermore, we showed that obese normoglycemic family members of a type 2 diabetic proband failed to compensate for the insulin resistance of obesity by inc...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.24.3.472

    authors: Elbein SC,Sun J,Scroggin E,Teng K,Hasstedt SJ

    更新日期:2001-03-01 00:00:00

  • Effect of rimonabant on glycemic control in insulin-treated type 2 diabetes: the ARPEGGIO trial.

    abstract::OBJECTIVE To examine the efficacy and safety of rimonabant, a selective cannabinoid receptor type-1 antagonist, in patients with type 2 diabetes receiving insulin monotherapy. RESEARCH DESIGN AND METHODS Patients (n = 368; A1C > or =7%) were randomized to 20 mg/day rimonabant or placebo in this 48-week, double-blind, ...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc09-0455

    authors: Hollander PA,Amod A,Litwak LE,Chaudhari U,ARPEGGIO Study Group.

    更新日期:2010-03-01 00:00:00

  • Effect of topical basic fibroblast growth factor on the healing of chronic diabetic neuropathic ulcer of the foot. A pilot, randomized, double-blind, placebo-controlled study.

    abstract:OBJECTIVE:To assess the efficacy and safety of topical human recombinant basic fibroblast growth factor (bFGF) on the healing of diabetic neurotrophic foot ulcers. RESEARCH DESIGN AND METHODS:Seventeen diabetic patients suffering from chronic neuropathic ulcer of the plantar surface of the foot entered a pilot, random...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.18.1.64

    authors: Richard JL,Parer-Richard C,Daures JP,Clouet S,Vannereau D,Bringer J,Rodier M,Jacob C,Comte-Bardonnet M

    更新日期:1995-01-01 00:00:00

  • Pulse pressure and prediction of incident foot ulcers in type 2 diabetes.

    abstract:OBJECTIVE:To assess the relevance of pulse pressure as a predictor of foot ulcers in type 2 diabetic subjects. RESEARCH DESIGN AND METHODS:A cohort study was performed on a consecutive series of 1,945 type 2 diabetic outpatients without a foot ulcer at baseline. Incident foot ulcers were identified through the regiona...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-1679

    authors: Monami M,Vivarelli M,Desideri CM,Colombi C,Marchionni N,Mannucci E

    更新日期:2009-05-01 00:00:00

  • Adult respiratory distress syndrome complicating severely uncontrolled diabetes mellitus: report of nine cases and a review of the literature.

    abstract::We report the occurrence of the adult respiratory distress syndrome (ARDS) in association with uncontrolled diabetes in nine patients. In reviewing the literature we found nine similar cases reported in little over a decade. In most cases no condition known to precipitate ARDS was discovered. The evidence suggests tha...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.5.6.574

    authors: Carroll P,Matz R

    更新日期:1982-11-01 00:00:00

  • Higher levels of HDL cholesterol are associated with a decreased likelihood of albuminuria in patients with long-standing type 1 diabetes.

    abstract:OBJECTIVE:The objective of this study was to determine whether high levels of HDL cholesterol are associated with a lower prevalence of albuminuria RESEARCH DESIGN AND METHODS:We analyzed the lipid profiles of patients with type 1 diabetes of > or = 20 years duration in 42 patients with albuminuria (28 microalbuminuri...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.29.01.06.dc05-1583

    authors: Molitch ME,Rupp D,Carnethon M

    更新日期:2006-01-01 00:00:00

  • Vibratory and cooling detection thresholds compared with other tests in diagnosing and staging diabetic neuropathy.

    abstract::Increasingly more tests are being used to detect and characterize diabetic polyneuropathy, but their value in setting minimal criteria for the diagnosis of neuropathy and for staging severity remains inadequately studied. In 180 diabetics, we compared the percentage of patients with test abnormalities and associations...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.10.4.432

    authors: Dyck PJ,Bushek W,Spring EM,Karnes JL,Litchy WJ,O'Brien PC,Service FJ

    更新日期:1987-07-01 00:00:00

  • Readability of self-care instructional pamphlets for diabetic patients.

    abstract::The readability of written instructional materials for diabetic patients is an important consideration in their use. We assessed the readability of six commonly used patient teaching guides on diabetic self-care. In addition, two pamphlets developed by our program for diabetic patients with fifth to tenth grade readin...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.4.6.627

    authors: Leichter SB,Nieman JA,Moore RW,Collins P,Rhodes A

    更新日期:1981-11-01 00:00:00

  • Effect of automated bio-behavioral feedback on the control of type 1 diabetes.

    abstract:OBJECTIVE:To test the effect of an automated system providing real-time estimates of HbA(1c), glucose variability, and risk for hypoglycemia. RESEARCH DESIGN AND METHODS:For 1 year, 120 adults with type 1 diabetes (69 female/51 male, age = 39.1 [14.3] years, duration of diabetes 20.3 [12.9] years, HbA(1c) = 8.0 [1.5])...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc10-1366

    authors: Kovatchev BP,Mendosa P,Anderson S,Hawley JS,Ritterband LM,Gonder-Frederick L

    更新日期:2011-02-01 00:00:00

  • Increased insulin action and clearance in hyperthyroid newly diagnosed IDDM patient. Restoration to normal with antithyroid treatment.

    abstract::In a patient with hyperthyroidism and newly diagnosed insulin-dependent diabetes mellitus (IDDM), insulin action and clearance were studied before the initiation of antithyroid treatment and at 3-mo intervals for 1 yr thereafter. The sequential euglycemic clamp technique (5 mM) was used with insulin infusion rates of ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.12.5.319

    authors: Nijs HG,Radder JK,Frölich M,Krans HM

    更新日期:1989-05-01 00:00:00