Risk of Cardiovascular Disease and Death in Individuals With Prediabetes Defined by Different Criteria: The Whitehall II Study.

abstract：:Secondary failure to oral hypoglycemic agents (OHAs) is a possible outcome for non-insulin-dependent diabetes mellitus (NIDDM) patients and poses a serious therapeutic problem. In this study, we evaluated the effect of adding a single bedtime low-dose NPH insulin injection to the previous ineffective sulfonylurea ther...

journal_title：Diabetes care

authors： Trischitta V,Italia S,Borzi V,Tribulato A,Mazzarino S,Squatrito S,Vigneri R

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:The levels of the surrogate markers of cholesterol absorption (cholestanol and plant sterols) and synthesis (cholesterol precursors) in serum have suggested that in adult type 1 diabetes, cholesterol absorption is high and synthesis is low compared with type 2 diabetic or control subjects. Accordingly, these ...

journal_title：Diabetes care

authors： Järvisalo M,Raitakari O,Gylling H,Miettinen TA

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:Diet therapy in gestational diabetes mellitus (GDM) has focused on carbohydrate restriction but is poorly substantiated. In this pilot randomized clinical trial, we challenged the conventional low-carbohydrate/higher-fat (LC/CONV) diet, hypothesizing that a higher-complex carbohydrate/lower-fat (CHOICE) diet ...

journal_title：Diabetes care

authors： Hernandez TL,Van Pelt RE,Anderson MA,Reece MS,Reynolds RM,de la Houssaye BA,Heerwagen M,Donahoo WT,Daniels LJ,Chartier-Logan C,Janssen RC,Friedman JE,Barbour LA

更新日期：2016-01-01 00:00:00

abstract：:To investigate vascular responses in insulin-dependent diabetic patients both with and without retinopathy, we have assessed vasodilation by forearm transcutaneous pO2 measurement after 10 min of ischemia produced by a sphygmomanometer cuff. Diabetic patients with proliferative retinopathy had a delayed vasodilatory r...

journal_title：Diabetes care

authors： Haitas B,Barnes A,Shogry ME,Weindling M,Rolfe P,Turner RC

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To assess associations between dietary intake and rates of change in insulin resistance and β-cell function in Hispanic women with prior gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:Sixty-two nondiabetic Hispanic women with pregnancies complicated by GDM completed oral and intravenous glu...

journal_title：Diabetes care

authors： Chen Z,Watanabe RM,Stram DO,Buchanan TA,Xiang AH

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To provide a description of the clinical characteristics that distinguish individuals who withhold insulin for weight control from those who do not. Some individuals with insulin-dependent diabetes mellitus (IDDM) control their weight by withholding insulin and purging excessive calories. This process places ...

journal_title：Diabetes care

authors： Biggs MM,Basco MR,Patterson G,Raskin P

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:It has proved difficult to separate the role of the diabetic state as distinct from its complications in causing the elevation in erythrocyte sodium-lithium (Na-Li) countertransport activity that has been observed in diabetes. The present study sought to isolate the impact of diabetes on the countertransporte...

journal_title：Diabetes care

authors： Hardman TC,Dubrey SW,Leslie RD,Lant AF

更新日期：1996-01-01 00:00:00

abstract：:OBJECTIVE-Impaired endothelial function of resistance and conduit arteries can be detected in patients with type 1 diabetes. We studied whether a persistent improvement of endothelial function can be achieved by regular physical training. RESEARCH DESIGN AND METHODS-The study included 26 patients with type 1 diabetes ...

journal_title：Diabetes care

authors： Fuchsjäger-Mayrl G,Pleiner J,Wiesinger GF,Sieder AE,Quittan M,Nuhr MJ,Francesconi C,Seit HP,Francesconi M,Schmetterer L,Wolzt M

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:Intrauterine exposure to maternal type 1 diabetes is associated with a less favorable metabolic profile later in life. Nonalcoholic fatty liver disease is the hepatic manifestation of a cluster of metabolic abnormalities linked to insulin resistance. This study aimed to evaluate the effect of maternal pregest...

journal_title：Diabetes care

authors： Knorr S,Bytoft B,Lohse Z,Boisen AB,Clausen TD,Jensen RB,Damm P,Beck-Nielsen H,Holst JJ,Hartmann B,Møller HJ,Højlund K,Gravholt CH,Jensen DM

更新日期：2019-08-01 00:00:00

abstract：:There was a need to design a questionnaire that could accurately assess the activity patterns of Native Americans to evaluate the relationship between physical activity and diabetes. Such a questionnaire was developed and implemented into the data collection scheme of the prospective Pima Indian Study of Arizona. The ...

journal_title：Diabetes care

authors： Kriska AM,Knowler WC,LaPorte RE,Drash AL,Wing RR,Blair SN,Bennett PH,Kuller LH

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:To quantify age-related variability of insulin needs during day and night closed-loop insulin delivery. RESEARCH DESIGN AND METHODS:We retrospectively analyzed data from hybrid closed-loop studies involving young children (1-6 years old, n = 20), children (7-12 years, n = 21), adolescents (13-17 years, n = 1...

journal_title：Diabetes care

authors： Dovc K,Boughton C,Tauschmann M,Thabit H,Bally L,Allen JM,Acerini CL,Arnolds S,de Beaufort C,Bergenstal RM,Campbell F,Criego A,Dunger DB,Elleri D,Evans ML,Fröhlich-Reiterer E,Hofer S,Kapellen T,Leelarathna L,Pieber T

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To examine mortality rates and causes of death among subjects diagnosed with type 1 diabetes aged

journal_title：Diabetes care

authors： Feltbower RG,Bodansky HJ,Patterson CC,Parslow RC,Stephenson CR,Reynolds C,McKinney PA

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility that leptin levels may be predictive of the risk of ischemic heart disease (IHD) through the relationship of leptin to body fat. RESEARCH DESIGN AND METHODS:The Quebec Cardiovascular Study cohort consisted of 2,103 French-Canadian men without IHD in 1985 who were followed until...

journal_title：Diabetes care

authors： Couillard C,Lamarche B,Mauriège P,Cantin B,Dagenais GR,Moorjani S,Lupien PJ,Després JP

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To determine the occurrence of elevated fetal hemoglobin (HbF) among the diabetic population and determine the clinical situation of importance. RESEARCH DESIGN AND METHODS:A cross-sectional study was conducted. HbA1c and HbF were measured with high-performance liquid chromatography in 1,104 consecutive diab...

journal_title：Diabetes care

authors： Koskinen LK,Lahtela JT,Koivula TA

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:Direct medical cost of diabetes in the U.S. has been estimated to be 2.3 times higher relative to individuals without diabetes. This study examines trends in health care expenditures by expenditure category in U.S. adults with diabetes between 2002 and 2011. RESEARCH DESIGN AND METHODS:We analyzed 10 years o...

journal_title：Diabetes care

authors： Ozieh MN,Bishu KG,Dismuke CE,Egede LE

更新日期：2015-10-01 00:00:00

abstract：:It is now possible to virtually normalize ambient blood glucose levels in insulin-dependent diabetic women during pregnancy. Successful programs have been developed that utilize home blood glucose monitoring, physiologic delivery of insulin, and quantitation of caloric intake carefully matched to insulin dosage. The r...

journal_title：Diabetes care

authors： Jovanovic L,Peterson CM

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:To understand the interrelationship of coronary artery disease (CAD) risk factors including hyperlipidemia, hypertension, and glucose intolerance to prevent and better manage this disease. RESEARCH DESIGN AND METHODS:We performed a 100-g oral glucose tolerance test in 2,113 subjects, and we evaluated their p...

journal_title：Diabetes care

authors： Yamada N,Yoshinaga H,Sakurai N,Shimano H,Gotoda T,Ohashi Y,Yazaki Y,Kosaka K

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:No study has been conducted to evaluate the association between avascular necrosis of the femoral head and diabetes. This study's aim was to assess this issue in Taiwan. RESEARCH DESIGN AND METHODS:A population-based cohort study was performed to analyze the database of Taiwan's National Health Insurance Pro...

journal_title：Diabetes care

authors： Lai SW,Lin CL,Liao KF

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Whereas single assessments of cardiorespiratory fitness have been shown to predict lower incidence of type 2 diabetes, there are no data on long-term trends in fitness and risk. We investigated the relationship between long-term trends in fitness and the incidence of type 2 diabetes. RESEARCH DESIGN AND METH...

journal_title：Diabetes care

authors： Sawada SS,Lee IM,Naito H,Noguchi J,Tsukamoto K,Muto T,Higaki Y,Tanaka H,Blair SN

更新日期：2010-06-01 00:00:00

abstract：:We have examined insulin and glucagon degrading activities of muscle and fat tissues in 11 subjects (4 lean controls, 3 insulin-resistant obese subjects, 2 non-insulin-dependent diabetic subjects, and 2 insulin-treated diabetic subjects) and correlated degrading activity with (1) basal insulin level and (2) state of i...

journal_title：Diabetes care

authors： Kitabchi AE,Stentz FB,Cole C,Duckworth WC

更新日期：1979-09-01 00:00:00

abstract：OBJECTIVE:Differences in risk of erectile dysfunction (ED) by characteristics of diabetes among older men are not well understood. We examined the association of type and duration of diabetes with erectile function in men >50 years of age in a large prospective cohort study. RESEARCH DESIGN AND METHODS:Subjects includ...

journal_title：Diabetes care

authors： Bacon CG,Hu FB,Giovannucci E,Glasser DB,Mittleman MA,Rimm EB

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To investigate the association of carotid atherosclerosis and serum lipoprotein(a) [Lp(a)] concentrations in subjects with NIDDM. RESEARCH DESIGN AND METHODS:We measured carotid intima-media thickness (IMT) and Lp(a) concentrations in 117 NIDDM subjects. Subjects were divided into tertiles according to IMT v...

journal_title：Diabetes care

authors： Yamamoto M,Egusa G,Yamakido M

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:Type 2 diabetes is frequently complicated with atherogenic dyslipidemia. This study aimed to evaluate the efficacy and safety of pemafibrate (K-877) in patients with type 2 diabetes comorbid with hypertriglyceridemia. RESEARCH DESIGN AND METHODS:Patients were randomly assigned to three groups and received pl...

journal_title：Diabetes care

authors： Araki E,Yamashita S,Arai H,Yokote K,Satoh J,Inoguchi T,Nakamura J,Maegawa H,Yoshioka N,Tanizawa Y,Watada H,Suganami H,Ishibashi S

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To evaluate temporal trends in rates of initial lower extremity amputation (ILEA) among patients with diabetes in the Veterans Health Administration (VHA). RESEARCH DESIGN AND METHODS:Retrospective administrative data analysis of VHA clinic users with diabetes in fiscal years (FY) 2000 to 2004 (1 October 199...

journal_title：Diabetes care

authors： Tseng CL,Rajan M,Miller DR,Lafrance JP,Pogach L

更新日期：2011-05-01 00:00:00

abstract：:Significant data suggest that overt hyperglycemia, either observed with or without a prior diagnosis of diabetes, contributes to an increase in mortality and morbidity in hospitalized patients. In this regard, goal-directed insulin therapy has remained as the standard of care for achieving and maintaining glycemic con...

journal_title：Diabetes care

authors： Schwartz S,DeFronzo RA

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the presence and correlates of clinically relevant cognitive impairment in middle-aged adults with childhood-onset type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS:During 2010-2013, 97 adults diagnosed with T1D and aged <18 years (age and duration 49 ± 7 and 41 ± 6 ...

journal_title：Diabetes care

authors： Nunley KA,Rosano C,Ryan CM,Jennings JR,Aizenstein HJ,Zgibor JC,Costacou T,Boudreau RM,Miller R,Orchard TJ,Saxton JA

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:The recommendations for dietary fats in patients with type 2 diabetes are based largely on the impact of fatty acids on fasting serum lipid and glucose concentrations. How fatty acids affect postprandial insulin, glucose, and triglyceride concentrations, however, remains unclear. The objective of this study w...

journal_title：Diabetes care

authors： Shah M,Adams-Huet B,Brinkley L,Grundy SM,Garg A

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of hypoglycemia in patients with type I diabetes and impaired awareness of hypoglycemia by prospective assessment. RESEARCH DESIGN AND METHODS:A prospective study was undertaken for 12 months in 60 patients with type I diabetes: 29 had impaired awareness of hypoglycemia and 31 reta...

journal_title：Diabetes care

authors： Gold AE,MacLeod KM,Frier BM

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:Diabetes is associated with oxidative stress and increased mortality, but a possible correlation between leukocyte-endothelium interactions, oxidative stress, and silent myocardial ischemia (SMI) is yet to be confirmed. RESEARCH DESIGN AND METHODS:Mitochondrial dysfunction and interactions between leukocytes...

journal_title：Diabetes care

authors： Hernandez-Mijares A,Rocha M,Rovira-Llopis S,Bañuls C,Bellod L,de Pablo C,Alvarez A,Roldan-Torres I,Sola-Izquierdo E,Victor VM

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To compare the health service utilization and long-term outcomes of acute myocardial infarction (AMI) patients with and without diabetes in Ontario. RESEARCH DESIGN AND METHODS:We examined 25,697 patients from Ontario (6,052 and 19,645 patients with and without diabetes, respectively) who were hospitalized b...

journal_title：Diabetes care

authors： Alter DA,Khaykin Y,Austin PC,Tu JV,Hux JE

更新日期：2003-05-01 00:00:00