Delayed vascular reactivity to ischemia in diabetic microangiopathy.

abstract：OBJECTIVE:Survival analysis was performed on a prospectively followed cohort of patients with cystic fibrosis (CF) to determine the impact of the development of diabetes on survival. RESEARCH DESIGN AND METHODS:Clinical data were retrieved for patients diagnosed with CF-related diabetes (CFRD) at the Minnesota CF Cent...

journal_title：Diabetes care

authors： Milla CE,Billings J,Moran A

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:Little is known about the psychosocial challenges of adults living with type 1 diabetes or its impact on partner relationships. This qualitative study was undertaken to gain better understanding of these issues. RESEARCH DESIGN AND METHODS:Four focus groups were held, two with adult type 1 diabetic patients ...

journal_title：Diabetes care

authors： Trief PM,Sandberg JG,Dimmock JA,Forken PJ,Weinstock RS

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:The pharmacokinetics and glucodynamics of a new insulin analog, insulin lispro, and regular human insulin were compared and contrasted after subcutaneous administrations in femoral, deltoid, and abdominal injection sites. RESEARCH DESIGN AND METHODS:Single 0.2 U/kg doses of insulin lispro and regular insulin...

journal_title：Diabetes care

authors： ter Braak EW,Woodworth JR,Bianchi R,Cerimele B,Erkelens DW,Thijssen JH,Kurtz D

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to determine whether the haptoglobin (Hp) genotype was predictive of restenosis and major adverse cardiac events (MACEs) after percutaneous transluminal coronary angioplasty (PTCA) in individuals with diabetes. RESEARCH DESIGN AND METHODS:A consecutive series of 935 diabetic patien...

journal_title：Diabetes care

authors： Roguin A,Koch W,Kastrati A,Aronson D,Schomig A,Levy AP

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of normal aging on the protective responses against hypoglycemia, in view of the fact that type II diabetes is primarily a disease of aging, and its treatment is associated with risk of hypoglycemia with cognitive impairment. RESEARCH DESIGN AND METHODS:Plasma glucose was lowered st...

journal_title：Diabetes care

authors： Matyka K,Evans M,Lomas J,Cranston I,Macdonald I,Amiel SA

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess changes in the prevalence of preexisting diabetes (diabetes antedating pregnancy) and gestational diabetes mellitus (GDM) from 1999 through 2005. RESEARCH DESIGN AND METHODS:In this retrospective study of 175,249 women aged 13-58 years with 209,287 singleton deliveries...

journal_title：Diabetes care

authors： Lawrence JM,Contreras R,Chen W,Sacks DA

更新日期：2008-05-01 00:00:00

abstract：:OBJECTIVE The American Diabetes Association advocates insulin regimens for youth with type 1 diabetes that involve adjusting insulin dose based on carbohydrate intake and blood glucose level. Implementing these regimens requires knowledge about carbohydrate content of foods and subsequent calculations of insulin dose,...

journal_title：Diabetes care

authors： Koontz MB,Cuttler L,Palmert MR,O'Riordan M,Borawski EA,McConnell J,Kern EO

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To investigate factors related to glycemic management among members of a professional cycling team with type 1 diabetes over a 7-day Union Cycliste Internationale World Tour stage race. RESEARCH DESIGN AND METHODS:An observational evaluation of possible factors related to glycemic management and performance ...

journal_title：Diabetes care

authors： Scott SN,Christiansen MP,Fontana FY,Stettler C,Bracken RM,Hayes CA,Fisher M,Bode B,Lagrou PH,Southerland P,Riddell MC

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:This national, population-based study reports diabetes incidence based on oral glucose tolerance tests (OGTTs) and identifies risk factors for diabetes in Australians. RESEARCH DESIGN AND METHODS:The Australian Diabetes, Obesity and Lifestyle Study followed-up 5,842 participants over 5 years. Normal glycemia...

journal_title：Diabetes care

authors： Magliano DJ,Barr EL,Zimmet PZ,Cameron AJ,Dunstan DW,Colagiuri S,Jolley D,Owen N,Phillips P,Tapp RJ,Welborn TA,Shaw JE

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The objective of the present analysis was to evaluate the association of alanine aminotransferase (ALT) with directly measured insulin sensitivity (S(i)) in a large, multiethnic cohort of U.S. adults and to determine whether ALT adds to existing metabolic risk definitions in identifying subjects with insulin ...

journal_title：Diabetes care

authors： Hanley AJ,Wagenknecht LE,Festa A,D'Agostino RB Jr,Haffner SM

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Epidemiological studies and randomized clinical trials have demonstrated in various populations that resting heart rate (RHR) was an independent predictor of cardiovascular (CV) risk and all-cause mortality. However, few data specifically evaluated the relationship between RHR and long-term CV and renal compl...

journal_title：Diabetes care

authors： Miot A,Ragot S,Hammi W,Saulnier PJ,Sosner P,Piguel X,Torremocha F,Marechaud R,Hadjadj S

更新日期：2012-10-01 00:00:00

abstract：:Thirty-eight non-insulin-dependent diabetic patients within 130% of desirable body weight were given a 100-g oral glucose tolerance test (OGTT) at diagnosis and after at least 1 mo of dietary treatment with energy and carbohydrate restriction. Thirteen "responders" showed an improvement in fasting blood glucose, gluco...

journal_title：Diabetes care

authors： Sönksen PH,Lowy C,Perkins JR,Lim HS

更新日期：1984-05-01 00:00:00

abstract：OBJECTIVE:To investigate relationships between baseline factors and treatment-associated efficacy changes in type 2 diabetes. RESEARCH DESIGN:AND METHODS Multivariable analyses of treatment response in 1,229 type 2 diabetic patients with hypercholesterolemia who received ezetimibe/simvastatin or atorvastatin in a rand...

journal_title：Diabetes care

authors： Goldberg RB,Guyton JR,Mazzone T,Weinstock RS,Polis AB,Tipping D,Tomassini JE,Tershakovec AM

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:This study compared heart rate variability (HRV) parameters in youth with and without type 1 diabetes and explored potential contributors of altered HRV. RESEARCH DESIGN AND METHODS:HRV parameters were measured among 354 youth with type 1 diabetes (mean age 18.8 years, diabetes duration 9.8 years, and mean A...

journal_title：Diabetes care

authors： Jaiswal M,Urbina EM,Wadwa RP,Talton JW,D'Agostino RB Jr,Hamman RF,Fingerlin TE,Daniels S,Marcovina SM,Dolan LM,Dabelea D

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:We aimed to determine optimal blood pressure (BP) thresholds for minimizing coronary artery disease (CAD) risk in people with childhood-onset type 1 diabetes. RESEARCH DESIGN AND METHODS:The Pittsburgh Epidemiology of Diabetes Complications (EDC) Study participants without known CAD at baseline (n = 605) wer...

journal_title：Diabetes care

authors： Guo J,Brooks MM,Muldoon MF,Naimi AI,Orchard TJ,Costacou T

更新日期：2019-09-01 00:00:00

abstract：:Type II diabetic subjects were given 50 g protein, 50 g glucose, or 50 g glucose with 50 g protein as a single meal in random sequence. The plasma glucose and insulin response was determined over the subsequent 5 h. The plasma glucose area above the baseline following a glucose meal was reduced 34% when protein was gi...

journal_title：Diabetes care

authors： Nuttall FQ,Mooradian AD,Gannon MC,Billington C,Krezowski P

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:To provide reliable data on the incidence of insulin-dependent diabetes mellitus (IDDM) in children (< 15 years of age) in Avellaneda, Argentina. RESEARCH DESIGN AND METHODS:A registry was established in Avellaneda, Argentina. The first registry was started in 1989, retrospective data collection was updated ...

journal_title：Diabetes care

authors： Sereday MS,Martí ML,Damiano MM,Moser ME

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of treatment with the glucagon-like peptide 1 receptor agonist exenatide on weight loss and metabolic parameters in obese nondiabetic women. RESEARCH DESIGN AND METHODS:Forty-one obese women (aged 48 ± 11 years and BMI 33.1 ± 4.1 kg/m(2)) participated in a 35-week randomized, double...

journal_title：Diabetes care

authors： Dushay J,Gao C,Gopalakrishnan GS,Crawley M,Mitten EK,Wilker E,Mullington J,Maratos-Flier E

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To investigate the association of metabolic and lifestyle factors with possible diabetic polyneuropathy (DPN) and neuropathic pain in patients with early type 2 diabetes. RESEARCH DESIGN AND METHODS:We thoroughly characterized 6,726 patients with recently diagnosed diabetes. After a median of 2.8 years, we s...

journal_title：Diabetes care

authors： Christensen DH,Knudsen ST,Gylfadottir SS,Christensen LB,Nielsen JS,Beck-Nielsen H,Sørensen HT,Andersen H,Callaghan BC,Feldman EL,Finnerup NB,Jensen TS,Thomsen RW

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of ginseng on newly diagnosed non-insulin-dependent diabetes mellitus (NIDDM) patients. RESEARCH DESIGN AND METHODS:In this double-blind placebo-controlled study, 36 NIDDM patients were treated for 8 weeks with ginseng (100 or 200 mg) or placebo. Efficacy was evaluated with psychoph...

journal_title：Diabetes care

authors： Sotaniemi EA,Haapakoski E,Rautio A

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:We wanted to determine whether obesity, abdominal fat distribution, and physical inactivity act similarly and independently as risk factors for noninsulin-dependent diabetes mellitus (NIDDM) and impaired glucose tolerance (IGT) in Hindu and Muslim Asian Indians, African-origin Creoles, and Chinese Mauritians....

journal_title：Diabetes care

authors： Dowse GK,Zimmet PZ,Gareeboo H,George K,Alberti MM,Tuomilehto J,Finch CF,Chitson P,Tulsidas H

更新日期：1991-04-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence of beta-cell autoantigen-reactive peripheral T-cells in type 1 diabetes, we developed an immunoglobulin-free enzyme-linked immunospot (ELISPOT) assay and assessed its usefulness for diagnosing this disease. RESEARCH DESIGN AND METHODS:Cellular immune responses to beta -cell auto...

journal_title：Diabetes care

authors： Kotani R,Nagata M,Moriyama H,Nakayama M,Yamada K,Chowdhury SA,Chakrabarty S,Jin Z,Yasuda H,Yokono K

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:Raloxifene hydrochloride is a selective estrogen receptor modulator that to date has not been shown to cause hypertriglyceridemia in normal, diabetic, or hypertriglyceridemic women. This study was designed to assess the effect of raloxifene on serum triglycerides in postmenopausal women who have a history of ...

journal_title：Diabetes care

authors： Carr MC,Knopp RH,Brunzell JD,Wheeler BS,Zhu X,Lakshmanan M,Rosen AS,Anderson PW

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To describe the methods used to implement intensive and conventional therapies in the Diabetes Control and Complications Trial (DCCT) and the metabolic results that occurred with the different treatment regimens. RESEARCH DESIGN AND METHODS:The DCCT was a controlled clinical trial that demonstrated the benef...

journal_title：Diabetes care

authors：

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVE:Delayed gastric emptying and/or gastrointestinal symptoms occur in 30-50% of diabetic patients. Known contributing factors are autonomic neuropathy and acute hyperglycemia, but the role of gastric autoimmunity has never been investigated, although 15-20% of type 1 diabetic patients exhibit parietal cell antib...

journal_title：Diabetes care

authors： De Block CE,De Leeuw IH,Pelckmans PA,Callens D,Máday E,Van Gaal LF

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:This study examined the prognostic significance of diabetes and microvascular complications in patients with heart failure with preserved ejection fraction (HFpEF). RESEARCH DESIGN AND METHODS:This analysis included 3,385 patients (mean age 69 ± 9.6 years; 49% male; 89% white) with HFpEF from the Treatment o...

journal_title：Diabetes care

authors： Sandesara PB,O'Neal WT,Kelli HM,Samman-Tahhan A,Hammadah M,Quyyumi AA,Sperling LS

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To examine the hypothesis that hyperinsulinemia among relatives of NIDDM probands will increase the prevalence of DLPs, we measured insulin levels and examined the frequency of DLPs among NIDDM pedigree members. RESEARCH DESIGN AND METHODS:We performed 2-h 75-g OGTTs and measured lipid and insulin levels of ...

journal_title：Diabetes care

authors： Schumacher MC,Maxwell TM,Wu LL,Hunt SC,Williams RR,Elbein SC

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the hospital care rendered to hyperglycemic individuals who did not have a diagnosis of diabetes before admission. RESEARCH DESIGN AND METHODS:A total of 1,034 consecutively hospitalized adult patients at a 750-bed inner-city teaching hospital were evaluated. Patients with one or more plasma gluc...

journal_title：Diabetes care

authors： Levetan CS,Passaro M,Jablonski K,Kass M,Ratner RE

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:Blood pressure ranges associated with cardiovascular disease (CVD) events in advanced type 2 diabetes are not clear. Our objective was to determine whether baseline and follow-up (On-Study) systolic blood pressure (SBP), diastolic blood pressure (DBP), and SBP combined with DBP predict CVD events in the Veter...

journal_title：Diabetes care

authors： Anderson RJ,Bahn GD,Moritz TE,Kaufman D,Abraira C,Duckworth W,VADT Study Group.

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To study the influence of position changes on 24-h ambulatory blood pressure (ABP) in normotensive or mildly hypertensive normoalbuminuric patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:A cross-sectional evaluation of patients was staged according to the duration of diabetes (DD) and the presence...

journal_title：Diabetes care

authors： Benhamou PY,Mouret S,Quesada JL,Boizel R,Baguet JP,Halimi S,Mallion JM

更新日期：2001-09-01 00:00:00