Reduced heart rate variability among youth with type 1 diabetes: the SEARCH CVD study.

abstract：OBJECTIVE:To characterize immune checkpoint inhibitor-associated diabetes mellitus (ICI-DM) in a single-institution case series. RESEARCH DESIGN AND METHODS:Retrospective chart review of 18 patients with new-onset ICI-DM following anti-programmed cell death protein 1 (PD-1)/anti-programmed cell death protein ligand 1 ...

journal_title：Diabetes care

authors： Byun DJ,Braunstein R,Flynn J,Zheng J,Lefkowitz RA,Kanbour S,Girotra M

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of clinically obtainable improvements in metabolic control in patients with type 1 diabetes on biochemical cardiovascular risk factors. RESEARCH DESIGN AND METHODS:Blood and 24-h urinary samples were obtained from 49 patients with type 1 diabetes before and after a run-in period and af...

journal_title：Diabetes care

authors： Djurhuus MS,Henriksen JE,Klitgaard NA,Blaabjerg O,Thye-Rønn P,Altura BM,Altura BT,Beck-Nielsen H

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:To determine whether food insecurity--the inability to reliably afford safe and nutritious food--is associated with poor glycemic control and whether this association is mediated by difficulty following a healthy diet, diabetes self-efficacy, or emotional distress related to diabetes. RESEARCH DESIGN AND MET...

journal_title：Diabetes care

authors： Seligman HK,Jacobs EA,López A,Tschann J,Fernandez A

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Women with breast cancer and diabetes face worse outcomes than those with breast cancer without diabetes; however, the contribution of comorbidity to these disparities remains unclear. We evaluated the impact of diabetes on receipt of cancer treatments as well as mortality while accounting for other comorbidi...

journal_title：Diabetes care

authors： Lega IC,Austin PC,Fischer HD,Fung K,Krzyzanowska MK,Amir E,Lipscombe LL

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:In children with type 1 diabetes (T1D), severe hypoglycemia (SH) is associated with poorer cognition, but the association of SH with cognitive function in late life is unknown. Given the increasing life expectancy in people with T1D, understanding the role of SH in brain health is crucial. RESEARCH DESIGN AN...

journal_title：Diabetes care

authors： Lacy ME,Gilsanz P,Eng C,Beeri MS,Karter AJ,Whitmer RA

更新日期：2020-03-01 00:00:00

abstract：:One-third of men with obesity or type 2 diabetes have subnormal free testosterone concentrations. The lower free testosterone concentrations are observed in obese men at all ages, including adolescents at completion of puberty. The gonadotropin concentrations in these males are inappropriately normal; thus, these pati...

journal_title：Diabetes care

authors： Dhindsa S,Ghanim H,Batra M,Dandona P

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:The prevalence of systemic hypertension is increased in patients with diabetes. In this prospective, randomized, crossover clinical trial, we assessed antihypertensive effects of chronic intermittent intravenous insulin therapy (CIIIT) on insulin-dependent diabetes mellitus (IDDM) subjects with hypertension a...

journal_title：Diabetes care

authors： Aoki TT,Grecu EO,Prendergast JJ,Arcangeli MA,Meisenheimer R

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:We sought to compare perceived barriers to diabetes care between people with diabetes and different health professional groups. RESEARCH DESIGN AND METHODS:This was a cross-sectional, postal, open-questionnaire survey conducted in the Waikato district, New Zealand. A total of 3,890 individuals with diabetes ...

journal_title：Diabetes care

authors： Simmons D,Lillis S,Swan J,Haar J

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:The provariant of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor (PPAR)gamma has been identified as a risk allele for type 2 diabetes. The purpose of the present study was to reveal a significant association with pre-diabetic phenotypes in nondiabetic individuals based on a systematic...

journal_title：Diabetes care

authors： Tönjes A,Scholz M,Loeffler M,Stumvoll M

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To report U.S. national population-based rates and trends in diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) among adults, in both the emergency department (ED) and inpatient settings. RESEARCH DESIGN AND METHODS:We analyzed data from 1 January 2006 through 30 September 2015 from the N...

journal_title：Diabetes care

authors： Benoit SR,Hora I,Pasquel FJ,Gregg EW,Albright AL,Imperatore G

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:Many studies have shown that diabetes increases the risk of cardiovascular disease (CVD) in women to a greater extent than in men. One explanation could be that diabetes has more adverse effects on CVD risk factors in women than in men. We compared diabetes-associated differences in CVD risk factors in men an...

journal_title：Diabetes care

authors： Howard BV,Cowan LD,Go O,Welty TK,Robbins DC,Lee ET

更新日期：1998-08-01 00:00:00

abstract：:This paper provides some historical aspects on the research and development of Humulin (rDNA origin), the first human health-care product derived from rDNA technology more than a decade ago. Also referred to as biosynthetic human insulin, Humulin is currently produced via the human proinsulin route, using an Escherich...

journal_title：Diabetes care

authors： Chance RE,Frank BH

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between the C242T polymorphism of the p22 phox gene, an essential component of NAD(P)H oxidase in the vasculature, with intima-media thickness (IMT) of the carotid artery and risk factors for atherosclerosis in type 2 diabetic subjects. RESEARCH DESIGN AND METHODS:C242T polymorphi...

journal_title：Diabetes care

authors： Hayaishi-Okano R,Yamasaki Y,Kajimoto Y,Sakamoto K,Ohtoshi K,Katakami N,Kawamori D,Miyatsuka T,Hatazaki M,Hazama Y,Hori M

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:This study evaluated the feasibility, safety, and efficacy of day-and-night hybrid closed-loop insulin delivery in adolescents with type 1 diabetes under free-living conditions. RESEARCH DESIGN AND METHODS:In an open-label randomized crossover study, 12 suboptimally controlled adolescents on insulin pump the...

journal_title：Diabetes care

authors： Tauschmann M,Allen JM,Wilinska ME,Thabit H,Acerini CL,Dunger DB,Hovorka R

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Roux-en-Y gastric bypass (RYGB) ameliorates type 2 diabetes in severely obese patients through mechanisms beyond just weight loss, and it may benefit less obese diabetic patients. We determined the long-term impact of RYGB on patients with diabetes and only class I obesity. RESEARCH DESIGN AND METHODS:Sixty-...

journal_title：Diabetes care

authors： Cohen RV,Pinheiro JC,Schiavon CA,Salles JE,Wajchenberg BL,Cummings DE

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To determine the proportion of patients with gestational diabetes mellitus (GDM) who have serological characteristics typical of IDDM. RESEARCH DESIGN AND METHODS:Islet cell antibodies (ICAs), insulin autoantibodies (IAAs), GAD65, and IA-2 antibodies were measured in 145 pregnant women with GDM, 33 with impa...

journal_title：Diabetes care

authors： Dozio N,Beretta A,Belloni C,Castiglioni M,Rosa S,Bosi E,Bonifacio E

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:In this prospective, randomized, open trial, we compared the efficacy and safety of aspart insulin given subcutaneously at different time intervals to a standard low-dose intravenous (IV) infusion protocol of regular insulin in patients with uncomplicated diabetic ketoacidosis (DKA). RESEARCH DESIGN AND METH...

journal_title：Diabetes care

authors： Umpierrez GE,Cuervo R,Karabell A,Latif K,Freire AX,Kitabchi AE

更新日期：2004-08-01 00:00:00

abstract：:Thirty-eight non-insulin-dependent diabetic patients within 130% of desirable body weight were given a 100-g oral glucose tolerance test (OGTT) at diagnosis and after at least 1 mo of dietary treatment with energy and carbohydrate restriction. Thirteen "responders" showed an improvement in fasting blood glucose, gluco...

journal_title：Diabetes care

authors： Sönksen PH,Lowy C,Perkins JR,Lim HS

更新日期：1984-05-01 00:00:00

abstract：OBJECTIVE:Reductions in heart attack and stroke hospitalizations are well documented in the U.S. population with diabetes. We extended trend analyses to other cardiovascular disease (CVD) conditions, including stroke by type, and used four additional years of data. RESEARCH DESIGN AND METHODS:Using 1998-2014 National ...

journal_title：Diabetes care

authors： Burrows NR,Li Y,Gregg EW,Geiss LS

更新日期：2018-02-01 00:00:00

abstract：:A preliminary study was performed to estimate the effect of biosynthetic human insulin (BHI) produced by the Eli Lilly Company in comparison with purified pork insulin (PPI) from the same manufacturer. Immunologic studies were done using an intradermal skin test with both insulins and in vitro studies binding with ser...

journal_title：Diabetes care

authors： Federlin K,Laube H,Velcovsky HG

更新日期：1981-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of metformin on glycemic control, insulin resistance, and risk factors for cardiovascular disease in NIDDM subjects from two ethnic groups (Caucasian and Asian) with different risks of cardiovascular disease. RESEARCH DESIGN AND METHODS:A total of 27 subjects with NIDDM (17 Caucasi...

journal_title：Diabetes care

authors： Nagi DK,Yudkin JS

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:Age, diabetes, and elevated inflammatory markers independently increase the risk of functional decline. We examined the effect of C-reactive protein (CRP) and interleukin-6 (IL-6) on the incident mobility limitation in older adults with and without diabetes. RESEARCH DESIGN AND METHODS:We analyzed data from ...

journal_title：Diabetes care

authors： Figaro MK,Kritchevsky SB,Resnick HE,Shorr RI,Butler J,Shintani A,Penninx BW,Simonsick EM,Goodpaster BH,Newman AB,Schwartz AV,Harris TB

更新日期：2006-09-01 00:00:00

abstract：:Because of concerns about safety and expense associated with continuous subcutaneous insulin infusion (CSII), all people who had used CSII as of July 1982 were identified. Annual follow-up has resulted in data for up to 61 mo. Of the 92 nonpregnant registrees, 31 were less than 20 yr old, 36 were 20-29, and 25 were 30...

journal_title：Diabetes care

authors： Deeb LC,Williams PE

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:Exercise tolerance in patients with diabetes is frequently impaired due to noncardiac disease such as claudication and polyneuropathy. This study assesses the prognostic value of dobutamine stress myocardial perfusion imaging in patients with diabetes. RESEARCH DESIGN AND METHODS:A total of 207 consecutive d...

journal_title：Diabetes care

authors： Schinkel AF,Elhendy A,van Domburg RT,Bax JJ,Vourvouri EC,Sozzi FB,Valkema R,Roelandt JR,Poldermans D

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:We examined the effect of intrauterine diabetes exposure (IDE) on the incidence of diabetic end-stage renal disease (ESRD) in Pima Indians with type 2 diabetes. RESEARCH DESIGN AND METHODS:Individuals were followed from their first diabetic examination until December 2006, death, ESRD, or age of 45 years. R...

journal_title：Diabetes care

authors： Pavkov ME,Hanson RL,Knowler WC,Sievers ML,Bennett PH,Nelson RG

更新日期：2010-11-01 00:00:00

abstract：:This study examined the effect of age on the posthepatic delivery of oral glucose (PHDG) during steady-state conditions. We used an intravenous-oral modification of the euglycemic insulin-clamp technique to assess PHDG in six men aged 24-39 yr (young) and eight men aged 65-83 yr (old). Each subject underwent two studi...

journal_title：Diabetes care

authors： Tonino RP,Minaker KL,Rowe JW

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:The ability of the Adult Treatment Panel III (ATP III) criteria of metabolic syndrome to identify insulin-resistant subjects at increased cardiovascular risk is suboptimal, especially in the absence of obesity and diabetes. Nonalcoholic fatty liver disease (NAFLD) is associated with insulin resistance and is ...

journal_title：Diabetes care

authors： Musso G,Gambino R,Bo S,Uberti B,Biroli G,Pagano G,Cassader M

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:A common variant rs236918 in the PCSK7 gene has the strongest association with iron homeostasis and is related to insulin resistance. Dietary carbohydrate (CHO) modulates the genetic effect on insulin resistance. We examined whether 2-year weight-loss diets modify the effect of PCSK7 genetic variants on chang...

journal_title：Diabetes care

authors： Huang T,Huang J,Qi Q,Li Y,Bray GA,Rood J,Sacks FM,Qi L

更新日期：2015-03-01 00:00:00

abstract：:OBJECTIVE The American Diabetes Association advocates insulin regimens for youth with type 1 diabetes that involve adjusting insulin dose based on carbohydrate intake and blood glucose level. Implementing these regimens requires knowledge about carbohydrate content of foods and subsequent calculations of insulin dose,...

journal_title：Diabetes care

authors： Koontz MB,Cuttler L,Palmert MR,O'Riordan M,Borawski EA,McConnell J,Kern EO

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To determine whether the association between depressive symptoms and glycemic control is mediated by blood glucose monitoring (BGM). RESEARCH DESIGN AND METHODS:A total of 276 adolescents with type 1 diabetes (mean age +/- SD, 15.6 +/- 1.4 years) completed a measure of depressive symptoms. Sociodemographic a...

journal_title：Diabetes care

authors： McGrady ME,Laffel L,Drotar D,Repaske D,Hood KK

更新日期：2009-05-01 00:00:00