PCSK7 genotype modifies effect of a weight-loss diet on 2-year changes of insulin resistance: the POUNDS LOST trial.

abstract：OBJECTIVE:To quantify age-related variability of insulin needs during day and night closed-loop insulin delivery. RESEARCH DESIGN AND METHODS:We retrospectively analyzed data from hybrid closed-loop studies involving young children (1-6 years old, n = 20), children (7-12 years, n = 21), adolescents (13-17 years, n = 1...

journal_title：Diabetes care

authors： Dovc K,Boughton C,Tauschmann M,Thabit H,Bally L,Allen JM,Acerini CL,Arnolds S,de Beaufort C,Bergenstal RM,Campbell F,Criego A,Dunger DB,Elleri D,Evans ML,Fröhlich-Reiterer E,Hofer S,Kapellen T,Leelarathna L,Pieber T

更新日期：2019-07-01 00:00:00

abstract：:This paper describes systematic studies on the absorption kinetics of exogenous insulin from its subcutaneous tissue depot in 52 male nonobese volunteers (age 20-30 yr). Five experimental protocols were used: effect of changing injection site, effect of temperature change and local massage, effect of aprotinin and hum...

journal_title：Diabetes care

authors： Berger M,Cüppers HJ,Hegner H,Jörgens V,Berchtold P

更新日期：1982-03-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to compare clinical and biomechanical characteristics of balance in diabetic polyneuropathic elderly patients and normal age-matched subjects. RESEARCH DESIGN AND METHODS:Fifteen elderly with distal neuropathy (DNP) and 15 healthy age-matched subjects were evaluated with the b...

journal_title：Diabetes care

authors： Corriveau H,Prince F,Hébert R,Raîche M,Tessier D,Maheux P,Ardilouze JL

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Determine the efficacy of a home-based walking intervention to improve walking ability and quality of life in people with diabetes and peripheral arterial disease (PAD). RESEARCH DESIGN AND METHODS:We conducted a randomized, controlled, single-blind trial within university-affiliated clinics in our local com...

journal_title：Diabetes care

authors： Collins TC,Lunos S,Carlson T,Henderson K,Lightbourne M,Nelson B,Hodges JS

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Insulin pump therapy (continuous subcutaneous insulin infusion [CSII]) and multiple daily injections (MDIs) with insulin glargine as basal insulin and mealtime insulin lispro have not been prospectively compared in people naïve to either regimen in a multicenter study. We aimed to help close that deficiency. ...

journal_title：Diabetes care

authors： Bolli GB,Kerr D,Thomas R,Torlone E,Sola-Gazagnes A,Vitacolonna E,Selam JL,Home PD

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of glyburide versus metformin and their combination for the treatment of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:In this prospective randomized controlled study, we randomly assigned patients with GDM at 13-33 weeks gestation and whose blood glucose...

journal_title：Diabetes care

authors： Nachum Z,Zafran N,Salim R,Hissin N,Hasanein J,Gam Ze Letova Y,Suleiman A,Yefet E

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To study how type 2 diabetes adversely affects brain volumes, changes in volume, and cognitive function. RESEARCH DESIGN AND METHODS:Regional brain volumes and ischemic lesion volumes in 1,366 women, aged 72-89 years, were measured with structural brain magnetic resonance imaging (MRI). Repeat scans were col...

journal_title：Diabetes care

authors： Espeland MA,Bryan RN,Goveas JS,Robinson JG,Siddiqui MS,Liu S,Hogan PE,Casanova R,Coker LH,Yaffe K,Masaki K,Rossom R,Resnick SM,WHIMS-MRI Study Group.

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Failure to meet goals for glycemic control in primary care settings may be due in part to lack of information critical to guide intensification of therapy. Our objective is to determine whether rapid-turnaround A1c availability would improve intensification of diabetes therapy and reduce A1c levels in patient...

journal_title：Diabetes care

authors： Miller CD,Barnes CS,Phillips LS,Ziemer DC,Gallina DL,Cook CB,Maryman SD,El-Kebbi IM

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship of central fat distribution with gestational glucose tolerance during the usual time for screening gestational diabetes. RESEARCH DESIGN AND METHODS:This cross-sectional study investigated 1,113 consecutive women, > or = 20 years old, pregnant for approximately 21 to 28 weeks, wi...

journal_title：Diabetes care

authors： Branchtein L,Schmidt MI,Mengue SS,Reichelt AJ,Matos MC,Duncan BB

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To assess associations between dietary intake and rates of change in insulin resistance and β-cell function in Hispanic women with prior gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:Sixty-two nondiabetic Hispanic women with pregnancies complicated by GDM completed oral and intravenous glu...

journal_title：Diabetes care

authors： Chen Z,Watanabe RM,Stram DO,Buchanan TA,Xiang AH

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:The purpose of the 1992 Singapore National Health Survey was to determine the current distribution of major noncommunicable diseases and their risk factors, including the prevalence of diabetes and dyslipidemia, in Singapore. RESEARCH DESIGN AND METHODS:A combination of disproportionate stratified sampling a...

journal_title：Diabetes care

authors： Tan CE,Emmanuel SC,Tan BY,Jacob E

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:Dietary fiber has recently received recognition for reducing the risk of developing diabetes and heart disease. The implication is that it may have therapeutic benefit in prediabetic metabolic conditions. To test this hypothesis, we investigated the effect of supplementing a high-carbohydrate diet with fiber ...

journal_title：Diabetes care

authors： Vuksan V,Sievenpiper JL,Owen R,Swilley JA,Spadafora P,Jenkins DJ,Vidgen E,Brighenti F,Josse RG,Leiter LA,Xu Z,Novokmet R

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:The effects of longitudinal changes in the visceral fat area (VFA), and other anthropometric indices, on the risk factors of metabolic syndrome were not studied. We calculated the changes in metabolic risk factors in relation to changes in certain anthropometric indices in a large-scale study of Japanese men....

journal_title：Diabetes care

authors： Matsushita Y,Nakagawa T,Yamamoto S,Takahashi Y,Yokoyama T,Mizoue T,Noda M

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:Because readily available glycemic indicators are needed to guide clinical decision-making for intensification of diabetes therapy, our goals were to define the relationship between casual postprandial plasma glucose (cPPG) levels and HbA(1c) in patients with type 2 diabetes and to determine the predictive ch...

journal_title：Diabetes care

authors： El-Kebbi IM,Ziemer DC,Cook CB,Gallina DL,Barnes CS,Phillips LS

更新日期：2004-02-01 00:00:00

abstract：:The goal of this research was to quantify the relationships between patient survival and a set of explanatory variables in a randomly selected sample of community-based patients with non-insulin-dependent diabetes mellitus (NIDDM). The sample included 343 patients with NIDDM initially entered into the study in 1981-19...

journal_title：Diabetes care

authors： Davis WK,Hess GE,Hiss RG

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVE:The study aim was to determine if multisystemic therapy (MST), an intensive home-based psychotherapy, could reduce hospital admissions for diabetic ketoacidosis (DKA) in youth with poorly controlled type 1 diabetes over 24 months. Potential cost savings from reductions in admissions were also evaluated. RESE...

journal_title：Diabetes care

authors： Ellis D,Naar-King S,Templin T,Frey M,Cunningham P,Sheidow A,Cakan N,Idalski A

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:The current standard for hospital glucose management is point-of-care (POC) testing. We conducted a randomized controlled trial of real-time continuous glucose monitoring (RT-CGM) compared with POC in a non-intensive care unit (ICU) hospital setting. RESEARCH DESIGN AND METHODS:A total of 110 adults with typ...

journal_title：Diabetes care

authors： Fortmann AL,Spierling Bagsic SR,Talavera L,Garcia IM,Sandoval H,Hottinger A,Philis-Tsimikas A

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To examine the hypothesis that hyperinsulinemia among relatives of NIDDM probands will increase the prevalence of DLPs, we measured insulin levels and examined the frequency of DLPs among NIDDM pedigree members. RESEARCH DESIGN AND METHODS:We performed 2-h 75-g OGTTs and measured lipid and insulin levels of ...

journal_title：Diabetes care

authors： Schumacher MC,Maxwell TM,Wu LL,Hunt SC,Williams RR,Elbein SC

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:To compare diabetes care and outcomes among Haitians, African Americans, and non-Hispanic whites. RESEARCH DESIGN AND METHODS:We analyzed data from 715 Haitian, 1,472 African American, and 466 non-Hispanic white adults with diabetes using χ² testing and multiple logistic regression. RESULTS:Haitians had a h...

journal_title：Diabetes care

authors： Vimalananda VG,Rosenzweig JL,Cabral HJ,David MM,Lasser KE

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To investigate the triglyceride-glucose (TyG) index association with coronary artery calcification (CAC) progression in adult Koreans. RESEARCH DESIGN AND METHODS:Various cardiovascular risk factors and anthropometric profiles were assessed in 1,175 subjects who previously had a CAC evaluation at least twice...

journal_title：Diabetes care

authors： Park K,Ahn CW,Lee SB,Kang S,Nam JS,Lee BK,Kim JH,Park JS

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:This study assessed the ability to distinguish between type 1 diabetes-affected individuals and their unaffected relatives using HLA and single nucleotide polymorphism (SNP) genotypes. RESEARCH DESIGN AND METHODS:Eight models, ranging from only the high-risk DR3/DR4 genotype to all significantly associated H...

journal_title：Diabetes care

authors： Valdes AM,Varney MD,Erlich HA,Noble JA

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:We sought to test the hypothesis that a fixed-dose combination of trandolapril/verapamil-SR (T/V) is superior to a fixed-dose combination of losartan/hydrochlorothiazide (L/H) on glucose tolerance in hypertensive patients with impaired glucose tolerance (IGT). RESEARCH DESIGN AND METHODS:A prospective, rando...

journal_title：Diabetes care

authors： Bakris G,Molitch M,Hewkin A,Kipnes M,Sarafidis P,Fakouhi K,Bacher P,Sowers J,STAR Investigators.

更新日期：2006-12-01 00:00:00

abstract：:In search of possible interactions between plastic tubings used for insulin-pump treatment and commercial regular insulin preparations, various catheter sets made from polyvinyl chloride (PVC), polyethylene (PE), and nylon plastics were perfused at 30 degrees C in a laboratory setting for up to 72 h. The perfused insu...

journal_title：Diabetes care

authors： Chantelau E,Lange G,Gasthaus M,Boxberger M,Berger M

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:People with type 2 diabetes have impaired exercise responses even in the absence of cardiovascular complications. One key factor associated with the exercise intolerance is abnormally slowed oxygen uptake (VO2) kinetics during submaximal exercise. The mechanisms of this delayed adaptation during exercise are ...

journal_title：Diabetes care

authors： Bauer TA,Reusch JE,Levi M,Regensteiner JG

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between the use of ACE inhibitors and hospital admission for severe hypoglycemia and to explore the effects of potential confounding variables on this relationship. RESEARCH DESIGN AND METHODS:The association between the use of ACE inhibitors and the incidence of hypoglycemia is c...

journal_title：Diabetes care

authors： Morris AD,Boyle DI,McMahon AD,Pearce H,Evans JM,Newton RW,Jung RT,MacDonald TM

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:Adverse microbial exposures might contribute to diabetogenesis. We hypothesized that clinical periodontal disease (a manifestation of microbial exposures in dysbiotic biofilms) would be related to insulin resistance among diabetes-free participants. The roles of inflammatory mediation and effect modification ...

journal_title：Diabetes care

authors： Demmer RT,Squillaro A,Papapanou PN,Rosenbaum M,Friedewald WT,Jacobs DR Jr,Desvarieux M

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Lifestyle interventions slow development of type 2 diabetes by half, but the impact of health payer reimbursement for delivery of intervention programs is not well known. We evaluated net commercial health payer expenditures when offering reimbursement for access to YMCA's Diabetes Prevention Program (YDPP) i...

journal_title：Diabetes care

authors： Ackermann RT,Kang R,Cooper AJ,Liss DT,Holmes AM,Moran M,Saha C

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To examine psychometric properties of the Self-Care Inventory-revised (SCI-R), a self-report measure of perceived adherence to diabetes self-care recommendations, among adults with diabetes. RESEARCH DESIGN AND METHODS:We used three data sets of adult type 1 and type 2 diabetic patients to examine psychometr...

journal_title：Diabetes care

authors： Weinger K,Butler HA,Welch GW,La Greca AM

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To determine the role of height and glycosylated hemoglobin in abnormal nerve conduction in pediatric patients with insulin-dependent (type I) diabetes mellitus. RESEARCH DESIGN AND METHODS:Sixty-six pediatric patients (aged 6.3-18.2 yr) with a duration of diabetes from 4 to 8.5 yr but free of clinical neuro...

journal_title：Diabetes care

authors： Duck SC,Wei FF,Parke J,Swick HM

更新日期：1991-05-01 00:00:00

abstract：:The relationship of two aspects of family life to metabolic control were examined as part of a longitudinal study of school-aged children with newly diagnosed insulin-dependent diabetes mellitus (IDDM). Glycosylated hemoglobin level was the primary index of metabolic control; weight-adjusted insulin dosage served as a...

journal_title：Diabetes care

authors： Kovacs M,Kass RE,Schnell TM,Goldston D,Marsh J

更新日期：1989-06-01 00:00:00