Differences in glucose tolerance between fixed-dose antihypertensive drug combinations in people with metabolic syndrome.

abstract：OBJECTIVE:Altered immune reactivity precedes and accompanies type 1 and type 2 diabetes. We hypothesized that the metabolic phenotype relates to the systemic cellular immune status. RESEARCH DESIGN AND METHODS:A total of 194 metabolically well-controlled patients with type 1 diabetes (n = 62, mean diabetes duration 1....

journal_title：Diabetes care

authors： Menart-Houtermans B,Rütter R,Nowotny B,Rosenbauer J,Koliaki C,Kahl S,Simon MC,Szendroedi J,Schloot NC,Roden M,German Diabetes Study Group.

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To describe the association between Bacille Calmette-Guérin (BCG) vaccination and IDDM development in two different case-control series (A and B) in Montreal. RESEARCH DESIGN AND METHODS:Case-control series A comprised 93 IDDM cases and 2,903 control subjects who participated in a community-based tuberculin ...

journal_title：Diabetes care

authors： Parent ME,Siemiatycki J,Menzies R,Fritschi L,Colle E

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:We examined the effects of metformin on diabetes prevention and the subgroups that benefited most over 15 years in the Diabetes Prevention Program (DPP) and its follow-up, the Diabetes Prevention Program Outcomes Study (DPPOS). RESEARCH DESIGN AND METHODS:During the DPP (1996-2001), adults at high risk of de...

journal_title：Diabetes care

authors： Diabetes Prevention Program Research Group.

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Mortality from acute diabetes-related events is greatly raised in young adults with type 1 diabetes. Psychosocial and socioeconomic risk factors are examined for deaths from acute events separately from deaths due to other causes. RESEARCH DESIGN AND METHODS:This study had a nested case-control design. The c...

journal_title：Diabetes care

authors： Laing SP,Jones ME,Swerdlow AJ,Burden AC,Gatling W

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To assess the mechanistic effects of the glucagon-like peptide 1 (GLP-1) receptor agonist liraglutide and the dipeptidyl peptidase 4 (DPP-4) inhibitor sitagliptin on (exocrine) pancreatic physiology and morphology. RESEARCH DESIGN AND METHODS:For this randomized, double-blind, parallel-group trial, 55 patien...

journal_title：Diabetes care

authors： Smits MM,Tonneijck L,Muskiet MH,Kramer MH,Pieters-van den Bos IC,Vendrik KE,Hoekstra T,Bruno MJ,Diamant M,van Raalte DH,Cahen DL

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To determine maternal parameters with the strongest influence on fetal growth in different periods of pregnancies complicated by an abnormal glucose tolerance test (GTT). RESEARCH DESIGN AND METHODS:Retrospective study of 368 women with gestational diabetes mellitus (GDM; > or = 2 abnormal GTT values, n = 28...

journal_title：Diabetes care

authors： Schaefer-Graf UM,Kjos SL,Kilavuz O,Plagemann A,Brauer M,Dudenhausen JW,Vetter K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Although the Diabetes Prevention Program (DPP) and the Finnish Diabetes Prevention Study (FDPS) demonstrated that weight loss from lifestyle change reduces type 2 diabetes incidence in patients with prediabetes, the translation into community settings has been difficult. The objective of this study is to repo...

journal_title：Diabetes care

authors： Katula JA,Vitolins MZ,Rosenberger EL,Blackwell CS,Morgan TM,Lawlor MS,Goff DC Jr

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of two doses of once-weekly dulaglutide, a glucagon-like peptide 1 receptor agonist, to sitagliptin in uncontrolled, metformin-treated patients with type 2 diabetes. The primary objective was to compare (for noninferiority and then superiority) dulaglutide 1.5 mg versus sita...

journal_title：Diabetes care

authors： Nauck M,Weinstock RS,Umpierrez GE,Guerci B,Skrivanek Z,Milicevic Z

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:This study evaluated the ability of the Building, Relating, Assessing, and Validating Outcomes (BRAVO) risk engine to accurately project cardiovascular outcomes in three major clinical trials-BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME), C...

journal_title：Diabetes care

authors： Shao H,Shi L,Fonseca VA

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:To investigate whether microalbuminuria is associated with markers of the acute-phase response in NIDDM and whether there are ethnic differences in this association among the three main racial groups in Malaysia. RESEARCH DESIGN AND METHODS:NIDDM patients of Chinese, Indian, and Malay origin attending a diab...

journal_title：Diabetes care

authors： Islam N,Kazmi F,Chusney GD,Mattock MB,Zaini A,Pickup JC

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:To compare blood glucose control and incidence of nocturnal hypoglycemia in adolescents with type 1 diabetes on multiple injection regimens managed with either an insulin analog combination or NPH insulin plus regular human insulin. RESEARCH DESIGN AND METHODS:In a randomized cross-over study, 28 adolescents...

journal_title：Diabetes care

authors： Murphy NP,Keane SM,Ong KK,Ford-Adams M,Edge JA,Acerini CL,Dunger DB

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:This study examined whether lipids modify the relationship between intensive glucose control (INT) and diabetic retinopathy (DR). RESEARCH DESIGN AND METHODS:The incidence and progression of DR were assessed in 858 of 1,791 participants with 7-field stereoscopic fundus photographs at baseline and 5 years lat...

journal_title：Diabetes care

authors： Azad N,Bahn GD,Emanuele NV,Agrawal L,Ge L,Reda D,Klein R,Reaven PD,Hayward R,VADT Study Group.

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Physical activity is integral to the management of type 2 diabetes. Unfortunately, the majority of adults with type 2 diabetes do not regularly engage in physical activity. The purpose of this study was to assess physical activity behavior and its correlates (i.e., physical activity knowledge, barriers, and p...

journal_title：Diabetes care

authors： Hays LM,Clark DO

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:The performance of glycated hemoglobin (HbA1c) and fasting plasma glucose (FPG) was compared in screening for diabetes by an oral glucose tolerance test (OGTT) in patients undergoing coronary angiography (CAG). RESEARCH DESIGN AND METHODS:Patients without known diabetes admitted for CAG were eligible. OGTT a...

journal_title：Diabetes care

authors： Wang JS,Lee IT,Lee WJ,Lin SY,Fu CP,Ting CT,Lee WL,Liang KW,Sheu WH

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The use of thiazolidinedione (TZD) derivatives is associated with fluid retention, especially when combined with insulin. Because TZDs improve the metabolic effect of insulin, they may also reverse the blunted vascular response to insulin. We hypothesize that improvement of the action of insulin on vascular t...

journal_title：Diabetes care

authors： Rennings AJ,Smits P,Stewart MW,Tack CJ

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate alcohol consumption in relation to the incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS:The study population consisted of 22778 twins of the Finnish Twin Cohort. This cohort was compiled in 1975 and includes all same-sexed twins born in Finland before 1958. I...

journal_title：Diabetes care

authors： Carlsson S,Hammar N,Grill V,Kaprio J

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Obesity is associated with alterations in corticolimbic-striatal brain regions involved in food motivation and reward. Stress and the presence of food cues may each motivate eating and engage corticolimibic-striatal neurocircuitry. It is unknown how these factors interact to influence brain responses and whet...

journal_title：Diabetes care

authors： Jastreboff AM,Sinha R,Lacadie C,Small DM,Sherwin RS,Potenza MN

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To examine the effect of pioglitazone on myocardial insulin sensitivity and left ventricular (LV) function in patients with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS:Twelve subjects with T2D and 12 with normal glucose tolerance received a euglycemic insulin clamp. Myocardial glucose uptake (MGU) and...

journal_title：Diabetes care

authors： Clarke GD,Solis-Herrera C,Molina-Wilkins M,Martinez S,Merovci A,Cersosimo E,Chilton RJ,Iozzo P,Gastaldelli A,Abdul-Ghani M,DeFronzo RA

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To examine the impact of Hurricane Katrina on the health of individuals with diabetes. RESEARCH DESIGN AND METHODS:This was an observational study in 1,795 adults with an A1C measurement 6 months before and 6-16 months after Hurricane Katrina in three health care systems: private (Tulane University Hospital ...

journal_title：Diabetes care

authors： Fonseca VA,Smith H,Kuhadiya N,Leger SM,Yau CL,Reynolds K,Shi L,McDuffie RH,Thethi T,John-Kalarickal J

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Diabetes is associated with oxidative stress and increased mortality, but a possible correlation between leukocyte-endothelium interactions, oxidative stress, and silent myocardial ischemia (SMI) is yet to be confirmed. RESEARCH DESIGN AND METHODS:Mitochondrial dysfunction and interactions between leukocytes...

journal_title：Diabetes care

authors： Hernandez-Mijares A,Rocha M,Rovira-Llopis S,Bañuls C,Bellod L,de Pablo C,Alvarez A,Roldan-Torres I,Sola-Izquierdo E,Victor VM

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To determine whether women with pregestational diabetes obtained long-term benefits from an intensive diabetes management program during pregnancy. RESEARCH DESIGN AND METHODS:Women with pregestational diabetes who had attended an intensive diabetes management program in pregnancy between 1991 and 1999 were ...

journal_title：Diabetes care

authors： Feig DS,Cleave B,Tomlinson G

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Psychophysical methods in patients with diabetes mellitus reveal deficits of central or foveal vision. Our aim was to evaluate the contrast-sensitivity thresholds in 24 insulin-dependent (type I) diabetic patients with a short disease duration and without retinopathy, taking into account metabolic control. R...

journal_title：Diabetes care

authors： Di Leo MA,Caputo S,Falsini B,Porciatti V,Minnella A,Greco AV,Ghirlanda G

更新日期：1992-05-01 00:00:00

abstract：:To investigate vascular responses in insulin-dependent diabetic patients both with and without retinopathy, we have assessed vasodilation by forearm transcutaneous pO2 measurement after 10 min of ischemia produced by a sphygmomanometer cuff. Diabetic patients with proliferative retinopathy had a delayed vasodilatory r...

journal_title：Diabetes care

authors： Haitas B,Barnes A,Shogry ME,Weindling M,Rolfe P,Turner RC

更新日期：1984-01-01 00:00:00

abstract：:In a 10-yr prospective population study 406 subjects who were 70 yr old received an oral glucose tolerance test. Of these subjects 169 were retested at 80. Three sets of diagnostic criteria were evaluated, of which the WHO criteria are recommended for screening studies in this age group. The prevalences of diabetes me...

journal_title：Diabetes care

authors： Agner E,Thorsteinsson B,Eriksen M

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:To study the influence of position changes on 24-h ambulatory blood pressure (ABP) in normotensive or mildly hypertensive normoalbuminuric patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:A cross-sectional evaluation of patients was staged according to the duration of diabetes (DD) and the presence...

journal_title：Diabetes care

authors： Benhamou PY,Mouret S,Quesada JL,Boizel R,Baguet JP,Halimi S,Mallion JM

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:In a few previous studies, cardiovascular disease (CVD) risk factors (RFs) have been shown to predict diabetes. Our objective was to determine whether the presence of CVD RFs predict the eventual development of diabetes after controlling for known RFs, such as directly measured insulin resistance and obesity....

journal_title：Diabetes care

authors： D'Agostino RB Jr,Hamman RF,Karter AJ,Mykkanen L,Wagenknecht LE,Haffner SM,Insulin Resistance Atherosclerosis Study Investigators.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:This study compares the time-action profile of inhaled insulin (INH; Exubera) with that of subcutaneously injected insulin lispro (ILP) or regular human insulin (RHI) in healthy volunteers. RESEARCH DESIGN AND METHODS:In this open-label, randomized, three-way, crossover study, 17 healthy male volunteers were...

journal_title：Diabetes care

authors： Rave K,Bott S,Heinemann L,Sha S,Becker RH,Willavize SA,Heise T

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To assess the association of 1-h plasma glucose (1hPG) and inflammation with normal glucose tolerance (NGT) and pre-diabetes. RESEARCH DESIGN AND METHODS:A cohort of 1,062 subjects was enrolled. After oral glucose load (oral glucose tolerance test), we compared subjects with NGT and pre-diabetes above and be...

journal_title：Diabetes care

authors： Bardini G,Dicembrini I,Cresci B,Rotella CM

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To 1) compare associations of diet-quality scores, which were inversely associated with cardiovascular disease, with incident type 2 diabetes and 2) test for differences in absolute-risk reduction across various strata. RESEARCH DESIGN AND METHODS:Men from the Health Professionals Follow-Up Study, who were i...

journal_title：Diabetes care

authors： de Koning L,Chiuve SE,Fung TT,Willett WC,Rimm EB,Hu FB

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To evaluate statin use in the U.S. before and after the 2015 American Diabetes Association position statement, which expanded statin therapy recommendations to include all adults 40-75 years old with diabetes. RESEARCH DESIGN AND METHODS:The National Health and Nutrition Examination Survey (NHANES) was used ...

journal_title：Diabetes care

authors： Leino AD,Dorsch MP,Lester CA

更新日期：2020-12-01 00:00:00