Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin.

abstract：OBJECTIVE:The structural basis of normoalbuminuric renal insufficiency in patients with type 2 diabetes remains to be elucidated. We compared renal biopsy findings in patients with type 2 diabetes and estimated glomerular filtration rate (eGFR) and measured GFR of <60 mL/min/1.73 m2, associated with either normo-, micr...

journal_title：Diabetes care

authors： Ekinci EI,Jerums G,Skene A,Crammer P,Power D,Cheong KY,Panagiotopoulos S,McNeil K,Baker ST,Fioretto P,Macisaac RJ

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Early use of insulin after diagnosis of type 2 diabetes is met with resistance because of associated weight gain, hypoglycemia, and fear of decreased compliance and quality of life (QoL). RESEARCH DESIGN AND METHODS:In treatment-naive patients with newly diagnosed type 2 diabetes, insulin and metformin were ...

journal_title：Diabetes care

authors： Lingvay I,Legendre JL,Kaloyanova PF,Zhang S,Adams-Huet B,Raskin P

更新日期：2009-10-01 00:00:00

abstract：:The concept of gestational diabetes goes back at least to 1946. Over the years, sophistication has increased regarding the pathophysiology of this condition. However, there is not universal agreement on how to diagnose gestational diabetes. The most widely used diagnostic criteria in the U.S. were validated by their p...

journal_title：Diabetes care

authors： Coustan DR,Carpenter MW

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:There is a well-documented gap between diabetes care guidelines and the services received by patients in most health care settings. This report presents 12-month follow-up results from a computer-assisted, patient-centered intervention to improve the level of recommended services patients received from a vari...

journal_title：Diabetes care

authors： Glasgow RE,Nutting PA,King DK,Nelson CC,Cutter G,Gaglio B,Rahm AK,Whitesides H

更新日期：2005-01-01 00:00:00

abstract：:Because the negative consequences of new-onset diabetes mellitus after transplantation (NODAT) diminish the significant gains of kidney transplantation, it is imperative to develop clinical interventions to reduce the incidence of NODAT. In this review, we discuss whether intensive lifestyle interventions that delay o...

journal_title：Diabetes care

authors： Chakkera HA,Weil EJ,Pham PT,Pomeroy J,Knowler WC

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Preclinical data suggest that linagliptin, a dipeptidyl peptidase-4 inhibitor, may lower urinary albumin excretion. The ability of linagliptin to lower albuminuria on top of renin-angiotensin-aldosterone system (RAAS) inhibition in humans was analyzed by pooling data from four similarly designed, 24-week, ran...

journal_title：Diabetes care

authors： Groop PH,Cooper ME,Perkovic V,Emser A,Woerle HJ,von Eynatten M

更新日期：2013-11-01 00:00:00

abstract：:Intranasal glucagon can raise blood glucose levels in healthy subjects. The aims of this study were to 1) compare the hyperglycemic effect of intranasal and intramuscular glucagon in healthy subjects and type I (insulin-dependent) diabetes patients during euglycemic conditions and 2) test the efficacy of intranasal an...

journal_title：Diabetes care

authors： Pontiroli AE,Calderara A,Pajetta E,Alberetto M,Pozza G

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:The sulfonylurea (SU) glyburide may cause severe and prolonged episodes of hypoglycemia. We aimed at investigating the impact of glyburide on glucose counterregulatory hormones during stepwise hypoglycemic clamp studies. RESEARCH DESIGN AND METHODS:We performed stepwise hypoglycemic clamp studies in 16 healt...

journal_title：Diabetes care

authors： ter Braak EW,Appelman AM,van der Tweel I,Erkelens DW,van Haeften TW

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Diabetic retinopathy (DR) is a leading cause of vision loss worldwide. Screening for DR is recommended in children and adolescents, but adherence is poor. Recently, autonomous artificial intelligence (AI) systems have been developed for early detection of DR and have been included in the American Diabetes Ass...

journal_title：Diabetes care

authors： Wolf RM,Liu TYA,Thomas C,Prichett L,Zimmer Galler I,Smith K,Abramoff MD,Channa R

更新日期：2021-01-21 00:00:00

abstract：OBJECTIVE:The role of fibrosis in early progressive renal decline in type 2 diabetes is unknown. Circulating WFDC2 (WAP four-disulfide core domain protein 2) and matrix metalloproteinase 7 (MMP-7; Matrilysin) are postulated to be biomarkers of renal fibrosis. This study examined an association of circulating levels of ...

journal_title：Diabetes care

authors： Ihara K,Skupien J,Kobayashi H,Md Dom ZI,Wilson JM,O'Neil K,Badger HS,Bowsman LM,Satake E,Breyer MD,Duffin KL,Krolewski AS

更新日期：2020-11-01 00:00:00

abstract：:This study investigates and compares human insulin (recombinant DNA) and purified porcine insulin (PPI) in healthy volunteers and in type II diabetic patients, in terms of whether both these insulins were capable of influencing in a different manner pancreatic glucagon, C-peptide, and free fatty acids (FFA) concentrat...

journal_title：Diabetes care

authors： Raptis S,Hadjidakis D,Enzmann F,Raptis A,Diamantopoulos E,Rosenthal J

更新日期：1982-11-01 00:00:00

abstract：:The effects of intravenous administration of potassium phosphate in the treatment of diabetic ketoacidosis were studied in nine children, ages 9 9/12 to 17 10/12 yr. During phosphate infusion (20--40 meq/L of fluid), all children maintained normal serum concentrations of phosphorus. Transient hypocalcemia occurred in ...

journal_title：Diabetes care

authors： Zipf WB,Bacon GE,Spencer ML,Kelch RP,Hopwood NJ,Hawker CD

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To compare lifestyle factors, cardiovascular risk factors, and coronary artery calcium (CAC) and abdominal aortic calcium (AAC) levels in Hispanic and non-Hispanic white (NHW) individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS:We recently demonstrated in a small group of nonreferred, healthy, nond...

journal_title：Diabetes care

authors： Reaven PD,Sacks J,Investigators for the Veterans Affairs Cooperative Study of Glycemic Control and Complications in Diabetes Mellitus Type 2.

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Few multiple lifestyle behavior change programs have been designed to reduce the risk of coronary heart disease in postmenopausal women with type 2 diabetes. This study tested the effectiveness of the Mediterranean Lifestyle Program (MLP), a comprehensive lifestyle self-management program (Mediterranean low-s...

journal_title：Diabetes care

authors： Toobert DJ,Glasgow RE,Strycker LA,Barrera M Jr,Radcliffe JL,Wander RC,Bagdade JD

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the frequency of sympathetic versus parasympathetic neuropathy among type 1 and type 2 diabetic patients. RESEARCH DESIGN AND METHODS:There were 43 patients with type 1 and 17 with type 2 diabetes who were investigated. Sympathetic nerve function was assessed by measurem...

journal_title：Diabetes care

authors： Freccero C,Svensson H,Bornmyr S,Wollmer P,Sundkvist G

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:It is still controversial whether sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) are equally effective in patients with diabetes. In these patients, multiple individual variables may be responsible for neointimal hyperplasia, thus making difficult the comparison of the two drug-eluting stent...

journal_title：Diabetes care

authors： Tomai F,Reimers B,De Luca L,Galassi AR,Gaspardone A,Ghini AS,Ferrero V,Favero L,Gioffrè G,Prati F,Tamburino C,Ribichini F

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:High birth weight is a risk factor for neonatal complications. It is not known if the risk differs with body proportionality. The primary aim of this study was to determine the risk of adverse pregnancy outcome in relation to body proportionality in large-for-gestational-age (LGA) infants stratified by matern...

journal_title：Diabetes care

authors： Persson M,Fadl H,Hanson U,Pasupathy D

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To examine glycemic control for the prevention of retinopathy in early diagnosed Japanese NIDDM patients. RESEARCH DESIGN AND METHODS:There were 137 patients with NIDDM but without retinopathy who first visited our facility from 1983-1985. Their age at diagnosis ranged from 30-65 years, with a disease durati...

journal_title：Diabetes care

authors： Nakagami T,Kawahara R,Hori S,Omori Y

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:We investigated whether islet autoantibody profile, HLA-DQ genotype, and age influenced a 20-year progression to diabetes from first autoantibody positivity (autoAb+) in first-degree relatives of patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Persistently islet autoAb+ siblings and offspring (n =...

journal_title：Diabetes care

authors： Gorus FK,Balti EV,Messaaoui A,Demeester S,Van Dalem A,Costa O,Dorchy H,Mathieu C,Van Gaal L,Keymeulen B,Pipeleers DG,Weets I,Belgian Diabetes Registry.

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To measure well-being and treatment satisfaction and their correlates in older people with diabetes. RESEARCH DESIGN AND METHODS:A postal survey was conducted of 1,000 diabetic patients aged > or = 60 years, representing 56% of the resident older diabetic population in an inner-city health district with a la...

journal_title：Diabetes care

authors： Petterson T,Lee P,Hollis S,Young B,Newton P,Dornan T

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:Prevalence and prognostic impact of cardiovascular disease differ between patients with or without diabetes. We aimed to explore differences in the prevalence and prognosis of myocardial ischemia by automated quantification of total perfusion deficit (TPD) among patients with and without diabetes. RESEARCH D...

journal_title：Diabetes care

authors： Han D,Rozanski A,Gransar H,Sharir T,Einstein AJ,Fish MB,Ruddy TD,Kaufmann PA,Sinusas AJ,Miller EJ,Bateman TM,Dorbala S,Di Carli M,Liang JX,Hu LH,Germano G,Dey D,Berman DS,Slomka PJ

更新日期：2020-02-01 00:00:00

abstract：:In children with insulin-dependent diabetes mellitus (IDDM), deterioration in metabolic control frequently occurs during early adolescence. To prevent this predictable increase in blood glucose levels, we randomly assigned young adolescents with IDDM to an intervention based on problem solving with self-monitoring of ...

journal_title：Diabetes care

authors： Anderson BJ,Wolf FM,Burkhart MT,Cornell RG,Bacon GE

更新日期：1989-03-01 00:00:00

abstract：:The consensus algorithm for the medical management of type 2 diabetes was published in August 2006 with the expectation that it would be updated, based on the availability of new interventions and new evidence to establish their clinical role. The authors continue to endorse the principles used to develop the algorith...

journal_title：Diabetes care

authors： Nathan DM,Buse JB,Davidson MB,Ferrannini E,Holman RR,Sherwin R,Zinman B,American Diabetes Association.,European Association for Study of Diabetes.

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:Previous studies demonstrate that the metabolic syndrome is associated with distal symmetric polyneuropathy (DSP). We aimed to determine the magnitude of this effect and the precise components involved. RESEARCH DESIGN AND METHODS:We determined the symptomatic DSP prevalence in the Health, Aging, and Body Co...

journal_title：Diabetes care

authors： Callaghan BC,Xia R,Banerjee M,de Rekeneire N,Harris TB,Newman AB,Satterfield S,Schwartz AV,Vinik AI,Feldman EL,Strotmeyer ES,Health ABC Study.

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To examine the absorption of glucagon-like peptide (GLP)-1(7-36) amide from the buccal mucosa of type 2 diabetic patients. Previously, the effects of the peptide have been studied following intravenous and subcutaneous injection. Now, a mucoadhesive, biodegradable buccal GLP-1 tablet (9 mm) containing 119 nmo...

journal_title：Diabetes care

authors： Gutniak MK,Larsson H,Sanders SW,Juneskans O,Holst JJ,Ahrén B

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To determine the incidence of insulin-dependent diabetes mellitus (IDDM) in children aged 0-14 years in Kuwait, as part of the World Health Organization Multinational Collaborative Study (DIAMOND), and to determine if the incidence rates have increased. RESEARCH DESIGN AND METHODS:All cases of IDDM diagnosed...

journal_title：Diabetes care

authors： Shaltout AA,Qabazard MA,Abdella NA,LaPorte RE,al Arouj M,Ben Nekhi A,Moussa MA,al Khawari MA

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:To characterize the insulin sensitivity of overweight and obese 5- to 10-year-old (Tanner stage 1-3) African-American children screened for participation in a diabetes prevention study and to identify the association of insulin sensitivity with obesity, hyperlipidemia, and hypertension. RESEARCH DESIGN AND M...

journal_title：Diabetes care

authors： Young-Hyman D,Schlundt DG,Herman L,De Luca F,Counts D

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:We previously showed that in patients with diabetes mellitus, glycated hemoglobin (HbA1c) monitoring outside international guidance on testing frequency is widespread. Here we examined the relationship between testing frequency and diabetes control to test the hypothesis that retest interval is linked to chan...

journal_title：Diabetes care

authors： Driskell OJ,Holland D,Waldron JL,Ford C,Scargill JJ,Heald A,Tran M,Hanna FW,Jones PW,Pemberton RJ,Fryer AA

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Inflammatory activity is increased in type 1 diabetes and may predispose to vascular disease. Its origin is not clear. We therefore investigated determinants of inflammation in type 1 diabetes. RESEARCH DESIGN AND METHODS:We performed a nested case-control study from the EURODIAB Prospective Complications St...

journal_title：Diabetes care

authors： Schram MT,Chaturvedi N,Schalkwijk C,Giorgino F,Ebeling P,Fuller JH,Stehouwer CD,EURODIAB Prospective Complications Study.

更新日期：2003-07-01 00:00:00

abstract：:OBJECTIVE Pharmacological profiles of biphasic insulin aspart 30/70 (BIAsp 30) once daily (OD), twice daily (b.i.d.), and three times daily (t.i.d.) were compared with other insulin regimens in two crossover glucose clamp studies of insulin-treated type 2 diabetic patients. RESEARCH DESIGNS AND METHODS Study 1 consist...

journal_title：Diabetes care

authors： Heise T,Heinemann L,Hövelmann U,Brauns B,Nosek L,Haahr HL,Olsen KJ

更新日期：2009-08-01 00:00:00