Head-to-head comparison of sirolimus- and paclitaxel-eluting stent in the same diabetic patient with multiple coronary artery lesions: a prospective, randomized, multicenter study.

Abstract:

OBJECTIVE:It is still controversial whether sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) are equally effective in patients with diabetes. In these patients, multiple individual variables may be responsible for neointimal hyperplasia, thus making difficult the comparison of the two drug-eluting stents (DES). RESEARCH DESIGN AND METHODS:We designed a prospective, randomized study to compare the efficacy in prevention of restenosis of SES and PES, both implanted in the same diabetic patient with multiple de novo coronary artery lesions undergoing elective percutaneous coronary intervention. We enrolled 60 patients with diabetes with at least two significant de novo angiographic stenoses in different coronary segments. The primary end point was in-stent late luminal loss (LLL) at 8-month angiographic follow-up. RESULTS:A total of 120 lesions were successfully treated with the randomly assigned DES (SES, n = 60; PES, n = 60). In-stent LLL was lower in the SES than in the PES group (0.26 +/- 0.4 vs. 0.50 +/- 0.6 mm; P = 0.01). Coronary lesions treated with SES presented a reduced in-stent LLL in 40 (68%) patients, while PES resulted in a lower in-stent LLL in 19 (32%) patients (P = 0.0002). At multivariable analysis, the type of DES implanted was the only independent predictor of in-stent LLL (odds ratio 2.3 [95% CI 1.1-5.0]; P = 0.03). CONCLUSIONS:SES directly compared with PES in the same diabetic patient is associated with a decrease in the extent of in-stent LLL at 8 months, suggesting a reduced risk of restenosis.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Tomai F,Reimers B,De Luca L,Galassi AR,Gaspardone A,Ghini AS,Ferrero V,Favero L,Gioffrè G,Prati F,Tamburino C,Ribichini F

doi

10.2337/dc07-1377

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

15-9

issue

1

eissn

0149-5992

issn

1935-5548

pii

dc07-1377

journal_volume

31

pub_type

杂志文章,多中心研究,随机对照试验
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    abstract:OBJECTIVE:Observational studies have associated metformin use with a decreased risk of lung cancer incidence in patients with type 2 diabetes, but the studies had important methodological shortcomings. The objective of this study was to determine whether metformin use is associated with a decreased risk of lung cancer ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-0740

    authors: Smiechowski BB,Azoulay L,Yin H,Pollak MN,Suissa S

    更新日期:2013-01-01 00:00:00

  • Association of elevated serum ferritin levels and the risk of gestational diabetes mellitus in pregnant women: The Camden study.

    abstract::OBJECTIVE- We examined the influence of a moderately elevated serum ferritin level at entry to care on the risk of gestational diabetes mellitus (GDM) and a possible mechanism (increased iron stores versus inflammation). RESEARCH DESIGN AND METHODS- In a prospective observational study with 1,456 healthy pregnant wome...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.2951077

    authors: Chen X,Scholl TO,Stein TP

    更新日期:2006-05-01 00:00:00

  • Acute effects of insulin in the control of VLDL production in humans. Implications for the insulin-resistant state.

    abstract::The role of hyperinsulinemia in the pathogenesis of triglyceride (TG) and VLDL over-production in insulin-resistant states remains controversial. While studies in humans and animals have generally suggested that chronic hyperinsulinemia facilitates VLDL production, particularly in the presence of an abundant supply of...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:10.2337/diacare.19.4.390

    authors: Lewis GF,Steiner G

    更新日期:1996-04-01 00:00:00

  • The use of insulin pumps with meal bolus alarms in children with type 1 diabetes to improve glycemic control.

    abstract:OBJECTIVE:The aim of this study was to determine whether the use of meal bolus alarms would result in fewer missed meal boluses per week in youth with type 1 diabetes using continuous subcutaneous insulin infusion (CSII) therapy. RESEARCH DESIGN AND METHODS:This was a randomized trial of 48 youth using CSII, who were ...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/diacare.2951012

    authors: Chase HP,Horner B,McFann K,Yetzer H,Gaston J,Banion C,Fiallo-Scharer R,Slover R,Klingensmith G

    更新日期:2006-05-01 00:00:00

  • The dynamics of diabetes among birth cohorts in the U.S.

    abstract::OBJECTIVE Using a nationally representative sample of the civilian noninstitutionalized U.S. population, we estimated trends in diabetes prevalence across cohorts born 1910-1989 and provide the first estimates of age-specific diabetes incidence using nationally representative, measured data. RESEARCH DESIGN AND METHOD...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc13-1982

    authors: Fishman EI,Stokes A,Preston SH

    更新日期:2014-04-01 00:00:00

  • Asian Americans: diabetes prevalence across U.S. and World Health Organization weight classifications.

    abstract:OBJECTIVE:To compare diabetes prevalence among Asian Americans by World Health Organization and U.S. BMI classifications. RESEARCH DESIGN AND METHODS:Data on Asian American adults (n = 7,414) from the National Health Interview Survey for 1997-2005 were analyzed. Diabetes prevalence was estimated across weight and ethn...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-0573

    authors: Oza-Frank R,Ali MK,Vaccarino V,Narayan KM

    更新日期:2009-09-01 00:00:00

  • Long-term metabolic and immunological follow-up of nonimmunosuppressed patients with type 1 diabetes treated with microencapsulated islet allografts: four cases.

    abstract:OBJECTIVE:To assess long-term metabolic and immunological follow-up of microencapsulated human islet allografts in nonimmunosuppressed patients with type 1 diabetes (T1DM). RESEARCH DESIGN AND METHODS:Four nonimmunosuppressed patients, with long-standing T1DM, received intraperitoneal transplant (TX) of microencapsula...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc11-0731

    authors: Basta G,Montanucci P,Luca G,Boselli C,Noya G,Barbaro B,Qi M,Kinzer KP,Oberholzer J,Calafiore R

    更新日期:2011-11-01 00:00:00

  • Pioglitazone treatment improves nitrosative stress in type 2 diabetes.

    abstract:OBJECTIVE:The purpose of this study was to determine the effect of 24 weeks of treatment with 45 mg/day pioglitazone on peripheral skin blood flow (SkBF) and skin nitric oxide (NO) production in vivo in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:This was a randomized, parallel, cross-over, double-blind...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/diacare.29.04.06.dc05-0517

    authors: Vinik AI,Ullal J,Parson HK,Barlow PM,Casellini CM

    更新日期:2006-04-01 00:00:00

  • Is pancreatic diabetes (type 3c diabetes) underdiagnosed and misdiagnosed?

    abstract::Exocrine pancreatic insufficiency is frequently associated with diabetes, with high prevalence in both insulin-dependent or insulin-independent patients. Exocrine pancreatic failure has often been perceived as a complication of diabetes. In contrast, recent clinical observations lead to the notion that nonendocrine pa...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:10.2337/dc08-s244

    authors: Hardt PD,Brendel MD,Kloer HU,Bretzel RG

    更新日期:2008-02-01 00:00:00

  • Rarefaction of the peripheral nerve network in diabetic patients is associated with a pronounced reduction of terminal Schwann cells.

    abstract:OBJECTIVE:Peripheral neuropathy is the most frequent neurological complication in diabetic patients. The diagnosis is established by both clinical neurological examination and demonstration of reduced epidermal nerve fibers in skin biopsies (1). Whereas the decrease of free nerve endings has been extensively studied in...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc07-1832

    authors: Reinisch CM,Traxler H,Piringer S,Tangl S,Nader A,Tschachler E

    更新日期:2008-06-01 00:00:00

  • Randomized prospective trial of pure porcine and conventional bovine/porcine insulin.

    abstract::Use of pure porcine insulin versus partially purified insulin of bovine/porcine origin might be expected to have certain clinical benefits, e.g., a lower incidence of skin reactions, a lower insulin dosage, better diabetes regulation, and greater preservation of endogenous insulin secretion. To test this hypothesis, w...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.10.3.337

    authors: Asplin C,Raghu P,Clemons P,Lyen K,Tatpati O,McKnight B,Baker L,Guthrie R,Sperling M,Palmer J

    更新日期:1987-05-01 00:00:00

  • Translating the chronic care model into the community: results from a randomized controlled trial of a multifaceted diabetes care intervention.

    abstract:OBJECTIVE:To determine whether using the chronic care model (CCM) in an underserved community leads to improved clinical and behavioral outcomes for people with diabetes. RESEARCH DESIGN AND METHODS:This multilevel, cluster-design, randomized controlled trial examined the effectiveness of a CCM-based intervention in a...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/diacare.29.04.06.dc05-1785

    authors: Piatt GA,Orchard TJ,Emerson S,Simmons D,Songer TJ,Brooks MM,Korytkowski M,Siminerio LM,Ahmad U,Zgibor JC

    更新日期:2006-04-01 00:00:00

  • Collaborative care management of major depression among low-income, predominantly Hispanic subjects with diabetes: a randomized controlled trial.

    abstract:OBJECTIVE:To determine whether evidence-based socioculturally adapted collaborative depression care improves receipt of depression care and depression and diabetes outcomes in low-income Hispanic subjects. RESEARCH DESIGN AND METHODS:This was a randomized controlled trial of 387 diabetic patients (96.5% Hispanic) with...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc09-1711

    authors: Ell K,Katon W,Xie B,Lee PJ,Kapetanovic S,Guterman J,Chou CP

    更新日期:2010-04-01 00:00:00

  • One-year glycemic control with a sulfonylurea plus pioglitazone versus a sulfonylurea plus metformin in patients with type 2 diabetes.

    abstract:OBJECTIVE:The goal was to assess the 1-year efficacy and safety of the addition of pioglitazone or metformin to existing sulfonylurea (SU) therapy in patients with inadequately controlled type 2 diabetes. RESEARCH DESIGN AND METHODS:In this multicenter, double-blind study, patients were randomized to receive either pi...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.2337/diacare.27.1.141

    authors: Hanefeld M,Brunetti P,Schernthaner GH,Matthews DR,Charbonnel BH,QUARTET Study Group.

    更新日期:2004-01-01 00:00:00

  • Autonomic nervous dysfunction in essential hypertension.

    abstract::Borderline hypertension, a condition in which the blood pressure oscillates between normal and high values, is a predictor of future more severe hypertension. Pathophysiologically, borderline hypertension is different from established hypertension. A large proportion of such patients have elevated cardiac output and a...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:10.2337/diacare.14.3.249

    authors: Julius S

    更新日期:1991-03-01 00:00:00

  • Glyburide Versus Metformin and Their Combination for the Treatment of Gestational Diabetes Mellitus: A Randomized Controlled Study.

    abstract:OBJECTIVE:To compare the efficacy and safety of glyburide versus metformin and their combination for the treatment of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:In this prospective randomized controlled study, we randomly assigned patients with GDM at 13-33 weeks gestation and whose blood glucose...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc16-2307

    authors: Nachum Z,Zafran N,Salim R,Hissin N,Hasanein J,Gam Ze Letova Y,Suleiman A,Yefet E

    更新日期:2017-03-01 00:00:00

  • Randomized trial of behavioral family systems therapy for diabetes: maintenance of effects on diabetes outcomes in adolescents.

    abstract:OBJECTIVE:Studies showing that family communication and conflict resolution are critical to effective management of type 1 diabetes in adolescents have stimulated interest in evaluating psychological treatments targeting these processes. Previous trials have shown that Behavioral Family Systems Therapy (BFST) improved ...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc06-1613

    authors: Wysocki T,Harris MA,Buckloh LM,Mertlich D,Lochrie AS,Mauras N,White NH

    更新日期:2007-03-01 00:00:00

  • Implementing a state-based cardiovascular disease and diabetes prevention program.

    abstract:OBJECTIVE:To evaluate weight loss and cardiometabolic risk reduction achieved through an adapted Diabetes Prevention Program intervention among adults at high risk for cardiovascular disease (CVD) and diabetes. RESEARCH DESIGN AND METHODS:Eight health care facilities implemented a group-based lifestyle intervention be...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-0862

    authors: Vanderwood KK,Hall TO,Harwell TS,Butcher MK,Helgerson SD,Montana Cardiovascular Disease and Diabetes Prevention Program Workgroup.

    更新日期:2010-12-01 00:00:00

  • Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention Trial-Type 1.

    abstract:OBJECTIVE:There is little information regarding the pattern of metabolic deterioration before the onset of type 1 diabetes. The goal of this study was to utilize data from the Diabetes Prevention Trial-Type 1 (DPT-1) to obtain a picture of the metabolic progression to type 1 diabetes over a period of approximately 2.5 ...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/diacare.29.03.06.dc05-1006

    authors: Sosenko JM,Palmer JP,Greenbaum CJ,Mahon J,Cowie C,Krischer JP,Chase HP,White NH,Buckingham B,Herold KC,Cuthbertson D,Skyler JS

    更新日期:2006-03-01 00:00:00

  • Severe Hypoglycemia and Cognitive Function in Older Adults With Type 1 Diabetes: The Study of Longevity in Diabetes (SOLID).

    abstract:OBJECTIVE:In children with type 1 diabetes (T1D), severe hypoglycemia (SH) is associated with poorer cognition, but the association of SH with cognitive function in late life is unknown. Given the increasing life expectancy in people with T1D, understanding the role of SH in brain health is crucial. RESEARCH DESIGN AN...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-0906

    authors: Lacy ME,Gilsanz P,Eng C,Beeri MS,Karter AJ,Whitmer RA

    更新日期:2020-03-01 00:00:00

  • Pubertal growth in IDDM is determined by HbA1c levels, sex, and bone age.

    abstract:OBJECTIVE:In cross-sectional studies of subjects with IDDM, the relationship between suboptimal pubertal growth, glycemic control, and abnormal insulin-like growth factor I (IGF-I) levels has proved difficult to define. The objective of this study was to examine these relationships in a longitudinal prospective study. ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.21.5.831

    authors: Ahmed ML,Connors MH,Drayer NM,Jones JS,Dunger DB

    更新日期:1998-05-01 00:00:00

  • Metabolic Syndrome Components Are Associated With Symptomatic Polyneuropathy Independent of Glycemic Status.

    abstract:OBJECTIVE:Previous studies demonstrate that the metabolic syndrome is associated with distal symmetric polyneuropathy (DSP). We aimed to determine the magnitude of this effect and the precise components involved. RESEARCH DESIGN AND METHODS:We determined the symptomatic DSP prevalence in the Health, Aging, and Body Co...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc16-0081

    authors: Callaghan BC,Xia R,Banerjee M,de Rekeneire N,Harris TB,Newman AB,Satterfield S,Schwartz AV,Vinik AI,Feldman EL,Strotmeyer ES,Health ABC Study.

    更新日期:2016-05-01 00:00:00

  • Linagliptin lowers albuminuria on top of recommended standard treatment in patients with type 2 diabetes and renal dysfunction.

    abstract:OBJECTIVE:Preclinical data suggest that linagliptin, a dipeptidyl peptidase-4 inhibitor, may lower urinary albumin excretion. The ability of linagliptin to lower albuminuria on top of renin-angiotensin-aldosterone system (RAAS) inhibition in humans was analyzed by pooling data from four similarly designed, 24-week, ran...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc13-0323

    authors: Groop PH,Cooper ME,Perkovic V,Emser A,Woerle HJ,von Eynatten M

    更新日期:2013-11-01 00:00:00

  • Acute pancreatitis in type 2 diabetes treated with exenatide or sitagliptin: a retrospective observational pharmacy claims analysis.

    abstract:OBJECTIVE:Cases of acute pancreatitis have been reported in association with exenatide, sitagliptin, and type 2 diabetes without use of these medications. It remains unknown whether exenatide or sitagliptin increase the risk of acute pancreatitis. RESEARCH DESIGN AND METHODS:A retrospective cohort study of a large med...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-0482

    authors: Garg R,Chen W,Pendergrass M

    更新日期:2010-11-01 00:00:00

  • Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial.

    abstract:OBJECTIVE:We evaluated whether the increasing number of genetic loci for coronary artery disease (CAD) identified in the general population could be used to predict the risk of major CAD events (MCE) among participants with type 2 diabetes at high cardiovascular risk. RESEARCH DESIGN AND METHODS:A weighted genetic ris...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc18-0709

    authors: Morieri ML,Gao H,Pigeyre M,Shah HS,Sjaarda J,Mendonca C,Hastings T,Buranasupkajorn P,Motsinger-Reif AA,Rotroff DM,Sigal RJ,Marcovina SM,Kraft P,Buse JB,Wagner MJ,Gerstein HC,Mychaleckyj JC,Parè G,Doria A

    更新日期:2018-11-01 00:00:00

  • Use of an islet cell antibody assay to identify type 1 diabetic patients with rapid decrease in C-peptide levels after clinical onset. Belgian Diabetes Registry.

    abstract:OBJECTIVE:To investigate whether the presence of antibody markers at diagnosis could help predict the rapid decrease in residual beta-cell function noted in some, but not all, patients with recent-onset type 1 diabetes. RESEARCH DESIGN AND METHODS:We measured random C-peptide levels (radioimmunoassay); islet cell cyto...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/diacare.23.8.1072

    authors: Decochez K,Keymeulen B,Somers G,Dorchy H,De Leeuw IH,Mathieu C,Rottiers R,Winnock F,ver Elst K,Weets I,Kaufman L,Pipeleers DG,Gorus FK,Belgian Diabetes Registry.

    更新日期:2000-08-01 00:00:00

  • Community screening for diabetes. Low detection rate in a low-risk population.

    abstract:OBJECTIVE:To evaluate glucose-based community screening for diabetes with regard to detection rate. RESEARCH DESIGN AND METHODS:A retrospective analysis of a community-screening questionnaire data base that included a screening for blood glucose. Referred subjects had fasting glucose levels > 6.4 mM (115 mg/dl) or pos...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.17.5.363

    authors: Newman WP,Nelson R,Scheer K

    更新日期:1994-05-01 00:00:00

  • Enhancing blood glucose awareness in adolescents and young adults with IDDM.

    abstract:OBJECTIVE:To determine the effectiveness of an intervention program designed to improve blood glucose awareness. RESEARCH DESIGN AND METHODS:Eight young-adult outpatients (mean age 22 yr) and six adolescent inpatients (mean age 14.5 yr) with insulin-dependent diabetes mellitus participated in the intervention program....

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.14.1.1

    authors: Nurick MA,Johnson SB

    更新日期:1991-01-01 00:00:00

  • A 16-week comparison of the novel insulin analog insulin glargine (HOE 901) and NPH human insulin used with insulin lispro in patients with type 1 diabetes.

    abstract:OBJECTIVE:To determine the safety and efficacy of the long-acting insulin analog, insulin glargine, as a component of basal bolus therapy in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Patients with type 1 diabetes receiving basal-bolus insulin treatment with NPH human insulin and insulin lispro were ra...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.2337/diacare.23.11.1666

    authors: Raskin P,Klaff L,Bergenstal R,Hallé JP,Donley D,Mecca T

    更新日期:2000-11-01 00:00:00

  • Incomplete elimination of the ABBOS epitope of bovine serum albumin under simulated gastrointestinal conditions of infants.

    abstract:OBJECTIVE:Because the bovine serum albumin residues 126-144 (ABBOS) have been reported to be responsible for the autoimmune reaction directed against pancreatic islet cells, it was our aim to study the potential survival of the ABBOS epitope during digestion in the gastrointestinal tract. RESEARCH DESIGN AND METHODS:E...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.5.875

    authors: Alting AC,Meijer RJ,van Beresteijn EC

    更新日期:1997-05-01 00:00:00