Randomized prospective trial of pure porcine and conventional bovine/porcine insulin.

abstract：OBJECTIVE:We conducted a nested case-control investigation to examine whether elevated baseline concentrations of cystatin C predicted progression from normoglycemia to pre-diabetes over 6 years of follow-up from the Western New York Health Study. RESEARCH DESIGN AND METHODS:In 2002-2004, 1,455 participants from the W...

journal_title：Diabetes care

authors： Donahue RP,Stranges S,Rejman K,Rafalson LB,Dmochowski J,Trevisan M

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:There is enough evidence that physical activity is an effective therapeutic tool in the management of type 2 diabetes. The present study was designed to validate a counseling strategy that could be used by physicians in their daily outpatient practice to promote the adoption and maintenance of physical activi...

journal_title：Diabetes care

authors： Di Loreto C,Fanelli C,Lucidi P,Murdolo G,De Cicco A,Parlanti N,Santeusanio F,Brunetti P,De Feo P

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To report U.S. national population-based rates and trends in diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) among adults, in both the emergency department (ED) and inpatient settings. RESEARCH DESIGN AND METHODS:We analyzed data from 1 January 2006 through 30 September 2015 from the N...

journal_title：Diabetes care

authors： Benoit SR,Hora I,Pasquel FJ,Gregg EW,Albright AL,Imperatore G

更新日期：2020-05-01 00:00:00

abstract：:The availability of insulin analogs has offered insulin replacement strategies that are proposed to more closely mimic normal human physiology. Specifically, there are a considerable number of reports demonstrating that prandial insulin analogs (lispro, aspart, glulisine) have pharmacokinetic and pharmacodynamic profi...

journal_title：Diabetes care

authors： Davidson MB

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To compare the effect of morning and bedtime NPH insulin combined with daytime sulfonylurea on glycemic control in non-insulin-dependent diabetes mellitus (NIDDM) patients no longer responding to treatment with sulfonylureas alone. RESEARCH DESIGN AND METHODS:Twenty-four NIDDM patients who fulfilled these cr...

journal_title：Diabetes care

authors： Groop LC,Widén E,Ekstrand A,Saloranta C,Franssila-Kallunki A,Schalin-Jäntti C,Eriksson JG

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:To estimate the within-person variability (SDi) for the overnight urinary albumin excretion rate (AER) in diabetic patients with persistent microalbuminuria. RESEARCH DESIGN AND METHODS:Thirteen normotensive diabetic patients in stable medical control, with normal renal function and without any associated ca...

journal_title：Diabetes care

authors： Phillipou G,Phillips PJ

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:Age, diabetes, and elevated inflammatory markers independently increase the risk of functional decline. We examined the effect of C-reactive protein (CRP) and interleukin-6 (IL-6) on the incident mobility limitation in older adults with and without diabetes. RESEARCH DESIGN AND METHODS:We analyzed data from ...

journal_title：Diabetes care

authors： Figaro MK,Kritchevsky SB,Resnick HE,Shorr RI,Butler J,Shintani A,Penninx BW,Simonsick EM,Goodpaster BH,Newman AB,Schwartz AV,Harris TB

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To assess the 12- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 versus placebo in patients with type 2 diabetes continuing metformin treatment. RESEARCH DESIGN AND METHODS:We conducted a 12-week, randomized, double-blind, placebo-controlled trial in 107 patients with type 2 diabetes wi...

journal_title：Diabetes care

authors： Ahrén B,Gomis R,Standl E,Mills D,Schweizer A

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:This study examined associations between BMI and mortality in individuals with normoglycemia, impaired fasting glucose (IFG), newly diagnosed diabetes, and prevalent diabetes and identified BMI ranges associated with the lowest mortality in each group. RESEARCH DESIGN AND METHODS:A total of 12,815,006 adults...

journal_title：Diabetes care

authors： Lee EY,Lee YH,Yi SW,Shin SA,Yi JJ

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Because readily available glycemic indicators are needed to guide clinical decision-making for intensification of diabetes therapy, our goals were to define the relationship between casual postprandial plasma glucose (cPPG) levels and HbA(1c) in patients with type 2 diabetes and to determine the predictive ch...

journal_title：Diabetes care

authors： El-Kebbi IM,Ziemer DC,Cook CB,Gallina DL,Barnes CS,Phillips LS

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Age at onset of type 1 diabetes influences the risk of microvascular complications. However, the long-term risk of proliferative retinopathy within the wide spectrum of age at onset of type 1 diabetes is less well known. RESEARCH DESIGN AND METHODS:A sample of 1,117 consecutively recruited patients was drawn...

journal_title：Diabetes care

authors： Hietala K,Harjutsalo V,Forsblom C,Summanen P,Groop PH,FinnDiane Study Group.

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of clinically obtainable improvements in metabolic control in patients with type 1 diabetes on biochemical cardiovascular risk factors. RESEARCH DESIGN AND METHODS:Blood and 24-h urinary samples were obtained from 49 patients with type 1 diabetes before and after a run-in period and af...

journal_title：Diabetes care

authors： Djurhuus MS,Henriksen JE,Klitgaard NA,Blaabjerg O,Thye-Rønn P,Altura BM,Altura BT,Beck-Nielsen H

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:To determine the impact of changes to treatment on the incidence of severe hypoglycemia and its risk factors in a large population-based cohort of children with type 1 diabetes. RESEARCH DESIGN AND METHODS:The cohort consisted of 1,335 children (age at entry 9.5 +/- 4.3 years [mean +/- SD], range 0-18), yiel...

journal_title：Diabetes care

authors： Bulsara MK,Holman CD,Davis EA,Jones TW

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:The current standard for hospital glucose management is point-of-care (POC) testing. We conducted a randomized controlled trial of real-time continuous glucose monitoring (RT-CGM) compared with POC in a non-intensive care unit (ICU) hospital setting. RESEARCH DESIGN AND METHODS:A total of 110 adults with typ...

journal_title：Diabetes care

authors： Fortmann AL,Spierling Bagsic SR,Talavera L,Garcia IM,Sandoval H,Hottinger A,Philis-Tsimikas A

更新日期：2020-11-01 00:00:00

abstract：:Glycated hemoglobin targets have been given in guidelines for the last three decades, mostly without change at around 6.5-7.0% (47-53 mmol/mol). Personalization of such targets has also long been advocated, but often with little and inappropriate guidance. More recently some have suggested higher targets might be indi...

journal_title：Diabetes care

authors： Home P

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Whether hyperglycemia in utero less than overt diabetes is associated with altered childhood glucose metabolism is unknown. We examined associations of gestational diabetes mellitus (GDM) not confounded by treatment with childhood glycemia in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) cohort. RES...

journal_title：Diabetes care

authors： Lowe WL Jr,Scholtens DM,Kuang A,Linder B,Lawrence JM,Lebenthal Y,McCance D,Hamilton J,Nodzenski M,Talbot O,Brickman WJ,Clayton P,Ma RC,Tam WH,Dyer AR,Catalano PM,Lowe LP,Metzger BE,HAPO Follow-up Study Cooperative Res

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:Prior studies have supported that waist circumference correlates better with visceral adipose tissue and is a better predictor of cardiovascular disease than are BMI and waist-to-hip ratio. In this study, we reexamine the role of waist size on the risk of hypertension and type 2 diabetes in African-origin pop...

journal_title：Diabetes care

authors： Okosun IS,Cooper RS,Rotimi CN,Osotimehin B,Forrester T

更新日期：1998-11-01 00:00:00

abstract：:The goal of this study was to investigate whether treatment with bezafibrate improves glucose tolerance in non-insulin-dependent diabetes mellitus (NIDDM). The study included 37 NIDDM patients with HbA1 concentrations greater than 8.5% and normal kidney and liver function who were being treated with diet alone or diet...

journal_title：Diabetes care

authors： Jones IR,Swai A,Taylor R,Miller M,Laker MF,Alberti KG

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:Whereas single assessments of cardiorespiratory fitness have been shown to predict lower incidence of type 2 diabetes, there are no data on long-term trends in fitness and risk. We investigated the relationship between long-term trends in fitness and the incidence of type 2 diabetes. RESEARCH DESIGN AND METH...

journal_title：Diabetes care

authors： Sawada SS,Lee IM,Naito H,Noguchi J,Tsukamoto K,Muto T,Higaki Y,Tanaka H,Blair SN

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To investigate the association between neck circumference and central obesity, overweight, and metabolic syndrome in Chinese individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 3,182 diabetic subjects (aged 20-80 years) were recruited from 15 community health centers in Beijing using a m...

journal_title：Diabetes care

authors： Yang GR,Yuan SY,Fu HJ,Wan G,Zhu LX,Bu XL,Zhang JD,Du XP,Li YL,Ji Y,Gu XN,Li Y,Beijing Community Diabetes Study Group.

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:Dietary fiber has recently received recognition for reducing the risk of developing diabetes and heart disease. The implication is that it may have therapeutic benefit in prediabetic metabolic conditions. To test this hypothesis, we investigated the effect of supplementing a high-carbohydrate diet with fiber ...

journal_title：Diabetes care

authors： Vuksan V,Sievenpiper JL,Owen R,Swilley JA,Spadafora P,Jenkins DJ,Vidgen E,Brighenti F,Josse RG,Leiter LA,Xu Z,Novokmet R

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To study the effect of birth weight on risk of type 2 diabetes in the schoolchildren in Taiwan. RESEARCH DESIGN AND METHODS:From 1992 to 1997, all schoolchildren aged 6-18 years were screened for diabetes in Taiwan Province. This cohort consisted of 1,966 patients with diabetes and 1,780 randomly selected su...

journal_title：Diabetes care

authors： Wei JN,Sung FC,Li CY,Chang CH,Lin RS,Lin CC,Chiang CC,Chuang LM

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To determine the effects of oxygen therapy in myocardial infarction (MI) patients with and without diabetes. RESEARCH DESIGN AND METHODS:In the Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction (DETO2X-AMI) trial, 6,629 normoxemic patients with suspected MI were randomized to oxyge...

journal_title：Diabetes care

authors： Nyström T,James SK,Lindahl B,Östlund O,Erlinge D,Herlitz J,Omerovic E,Mellbin L,Alfredsson J,Fröbert O,Jernberg T,Hofmann R,DETO2X-SWEDEHEART Investigators.

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To determine, after 1 yr of follow-up in type II diabetes patients, whether a statistically and clinically significant difference can be achieved in HbA1c between a standard therapy group and an intensively treated group, while maintaining HbA1c levels in both groups within ranges acceptable in regular commun...

journal_title：Diabetes care

authors： Abraira C,Emanuele N,Colwell J,Henderson W,Comstock J,Levin S,Nuttall F,Sawin C

更新日期：1992-11-01 00:00:00

abstract：:Type II diabetic subjects were given 50 g protein, 50 g glucose, or 50 g glucose with 50 g protein as a single meal in random sequence. The plasma glucose and insulin response was determined over the subsequent 5 h. The plasma glucose area above the baseline following a glucose meal was reduced 34% when protein was gi...

journal_title：Diabetes care

authors： Nuttall FQ,Mooradian AD,Gannon MC,Billington C,Krezowski P

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:Proteoglycan metabolism is altered in diabetic patients. The xylosyltransferases (XTs) are the initial and rate-limiting enzymes in the biosynthesis of the glycosaminoglycan chains in proteoglycans. Here, we analyzed whether the changed proteoglycan metabolism leads to altered serum XT levels in diabetic pati...

journal_title：Diabetes care

authors： Götting C,Kuhn J,Kleesiek K

更新日期：2008-10-01 00:00:00

abstract：:Of the 30,300 mothers who attended consecutively at the antenatal clinic during an 11-yr period, 3063 mothers screened positive using clinical criteria for potential diabetes in pregnancy. These 3063 mothers had a glucose tolerance test (GTT), of which 661 were judged abnormal. At different times an oral GTT, cortison...

journal_title：Diabetes care

authors： Hadden DR

更新日期：1980-05-01 00:00:00

abstract：OBJECTIVE:Recent studies have drawn attention to the adverse effects of ambient air pollutants such as particulate matter 2.5 (PM2.5) on human health. We evaluated the association between PM2.5 exposure and diabetes prevalence in the U.S. and explored factors that may influence this relationship. RESEARCH DESIGN AND M...

journal_title：Diabetes care

authors： Pearson JF,Bachireddy C,Shyamprasad S,Goldfine AB,Brownstein JS

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Mortality from acute diabetes-related events is greatly raised in young adults with type 1 diabetes. Psychosocial and socioeconomic risk factors are examined for deaths from acute events separately from deaths due to other causes. RESEARCH DESIGN AND METHODS:This study had a nested case-control design. The c...

journal_title：Diabetes care

authors： Laing SP,Jones ME,Swerdlow AJ,Burden AC,Gatling W

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To compare the diagnostic accuracy and time expenditure of screening models based on glycated hemoglobin (HbA(1c)) level and psychometric measures for mood disorder (MD) among children with type 1 diabetes. RESEARCH DESIGN AND METHODS:With semistructured clinical interviews (Schedule for Affective Disorders ...

journal_title：Diabetes care

authors： Butwicka A,Fendler W,Zalepa A,Szadkowska A,Mianowska B,Gmitrowicz A,Młynarski W

更新日期：2012-11-01 00:00:00