当前位置： SCI文献检索 > DIABETES CARE期刊下所有文献 > Association between fine particulate matter and diabetes prevalence in the U.S.

Association between fine particulate matter and diabetes prevalence in the U.S.

Abstract：

OBJECTIVE:Recent studies have drawn attention to the adverse effects of ambient air pollutants such as particulate matter 2.5 (PM2.5) on human health. We evaluated the association between PM2.5 exposure and diabetes prevalence in the U.S. and explored factors that may influence this relationship. RESEARCH DESIGN AND METHODS:The relationship between PM2.5 levels and diagnosed diabetes prevalence in the U.S. was assessed by multivariate regression models at the county level using data obtained from both the Centers for Disease Control and Prevention (CDC) and U.S. Environmental Protection Agency (EPA) for years 2004 and 2005. Covariates including obesity rates, population density, ethnicity, income, education, and health insurance were collected from the U.S. Census Bureau and the CDC. RESULTS:Diabetes prevalence increases with increasing PM2.5 concentrations, with a 1% increase in diabetes prevalence seen with a 10 μg/m(3) increase in PM2.5 exposure (2004: β = 0.77 [95% CI 0.39-1.25], P < 0.001; 2005: β = 0.81 [0.48-1.07], P < 0.001). This finding was confirmed for each study year in both univariate and multivariate models. The relationship remained consistent and significant when different estimates of PM2.5 exposure were used. Even for counties within guidelines for EPA PM2.5 exposure limits, those with the highest exposure showed a >20% increase in diabetes prevalence compared with that for those with the lowest levels of PM2.5, an association that persisted after controlling for diabetes risk factors. CONCLUSIONS:Our results suggest PM2.5 may contribute to increased diabetes prevalence in the adult U.S. population. These findings add to the growing evidence that air pollution is a risk factor for diabetes.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Pearson JF,Bachireddy C,Shyamprasad S,Goldfine AB,Brownstein JS

doi

10.2337/dc10-0698

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

2196-201

issue

10

eissn

0149-5992

issn

1935-5548

pii

dc10-0698

journal_volume

33

pub_type

杂志文章

相关文献

DIABETES CARE文献大全