Combination of insulin and metformin in the treatment of type 2 diabetes.

abstract：:This study compares the utility of nonenzymatically glycosylated serum proteins (lys-GSP) to glycosylated hemoglobins (HbA1a-c) as control indices of glucose homeostasis in patients with IDDM. The diagnostic value of lys-GSP was also examined in patients with non-insulin-dependent diabetes mellitus, in subjects with i...

journal_title：Diabetes care

authors： Schleicher ED,Gerbitz KD,Dolhofer R,Reindl E,Wieland OH,Edelmann E,Haslbeck M,Kemmler W,Walter H,Mehnert H

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:To 1) compare associations of diet-quality scores, which were inversely associated with cardiovascular disease, with incident type 2 diabetes and 2) test for differences in absolute-risk reduction across various strata. RESEARCH DESIGN AND METHODS:Men from the Health Professionals Follow-Up Study, who were i...

journal_title：Diabetes care

authors： de Koning L,Chiuve SE,Fung TT,Willett WC,Rimm EB,Hu FB

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To assess if low (1.25 mg) and/or standard (5 mg) doses of the ACE inhibitor ramipril could prevent progression of microalbuminuria (incipient diabetic nephropathy) in normotensive type 1 diabetic patients. RESEARCH DESIGN AND METHODS:This study, using a multicenter randomized placebo-controlled double-blind...

journal_title：Diabetes care

authors： O'Hare P,Bilbous R,Mitchell T,O' Callaghan CJ,Viberti GC,Ace-Inhibitor Trial to Lower Albuminuria in Normotensive Insulin-Dependent Subjects Study Group.

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:1) To examine trends in the use of diabetes medications and 2) to determine whether physicians individualize diabetes treatment as recommended by the American Diabetes Association (ADA). RESEARCH DESIGN AND METHODS:We conducted a retrospective, cross-sectional analysis of 2003-2016 National Health and Nutrit...

journal_title：Diabetes care

authors： Le P,Chaitoff A,Misra-Hebert AD,Ye W,Herman WH,Rothberg MB

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To investigate the association of folate and vitamin B12 in early pregnancy with gestational diabetes mellitus (GDM) risk. RESEARCH DESIGN AND METHODS:The data of this study were from a subcohort within the Shanghai Preconception Cohort Study. We included pregnancies with red blood cell (RBC) folate and vita...

journal_title：Diabetes care

authors： Chen X,Zhang Y,Chen H,Jiang Y,Wang Y,Wang D,Li M,Dou Y,Sun X,Huang G,Yan W

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Because quantifying glycans with complex structures is technically challenging, little is known about the association of glycosylation profiles with the renal prognosis in diabetic kidney disease (DKD). RESEARCH DESIGN AND METHODS:In 675 patients with type 2 diabetes, we assessed the baseline urinary glycan ...

journal_title：Diabetes care

authors： Mise K,Imamura M,Yamaguchi S,Teshigawara S,Tone A,Uchida HA,Eguchi J,Nakatsuka A,Ogawa D,Yoshida M,Yamada M,Shikata K,Wada J

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:This study examined associations between BMI and mortality in individuals with normoglycemia, impaired fasting glucose (IFG), newly diagnosed diabetes, and prevalent diabetes and identified BMI ranges associated with the lowest mortality in each group. RESEARCH DESIGN AND METHODS:A total of 12,815,006 adults...

journal_title：Diabetes care

authors： Lee EY,Lee YH,Yi SW,Shin SA,Yi JJ

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To examine the impact of Hurricane Katrina on the health of individuals with diabetes. RESEARCH DESIGN AND METHODS:This was an observational study in 1,795 adults with an A1C measurement 6 months before and 6-16 months after Hurricane Katrina in three health care systems: private (Tulane University Hospital ...

journal_title：Diabetes care

authors： Fonseca VA,Smith H,Kuhadiya N,Leger SM,Yau CL,Reynolds K,Shi L,McDuffie RH,Thethi T,John-Kalarickal J

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:We examined the associations of symptoms of sleep-disordered breathing (SDB), which was defined as loud snoring, stopping breathing for a while during sleep, and daytime sleepiness, and insomnia with glucose metabolism and incident type 2 diabetes in older adults. RESEARCH DESIGN AND METHODS:Between 1989 and...

journal_title：Diabetes care

authors： Strand LB,Carnethon M,Biggs ML,Djoussé L,Kaplan RC,Siscovick DS,Robbins JA,Redline S,Patel SR,Janszky I,Mukamal KJ

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To investigate whether the use of exogenous estrogen is associated with changes in the severity of diabetic retinopathy and the incidence of macular edema. RESEARCH DESIGN AND METHODS:The study design involved observation of two well-defined cohorts of women with diabetes. One group was diagnosed with diabet...

journal_title：Diabetes care

authors： Klein BE,Klein R,Moss SE

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To longitudinally characterize changes in insulin sensitivity in obese women during and after pregnancy. RESEARCH DESIGN AND METHODS:Six glucose-tolerant obese women underwent a 4-h euglycemic-hyperinsulinemic (500-600 pmol/l) clamping during the second (22.5 +/- 2 weeks [mean +/- SD]) and third trimester (3...

journal_title：Diabetes care

authors： Sivan E,Chen X,Homko CJ,Reece EA,Boden G

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:Given the transient nature of exercise-induced improvements in insulin sensitivity, it has been speculated that daily exercise is preferred to maximize the benefits of exercise for glycemic control. The current study investigates the impact of daily exercise versus exercise performed every other day on glycem...

journal_title：Diabetes care

authors： van Dijk JW,Tummers K,Stehouwer CD,Hartgens F,van Loon LJ

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:In this prospective, randomized, open trial, we compared the efficacy and safety of aspart insulin given subcutaneously at different time intervals to a standard low-dose intravenous (IV) infusion protocol of regular insulin in patients with uncomplicated diabetic ketoacidosis (DKA). RESEARCH DESIGN AND METH...

journal_title：Diabetes care

authors： Umpierrez GE,Cuervo R,Karabell A,Latif K,Freire AX,Kitabchi AE

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To determine the association between serum 25-hydroxyvitamin D (25OHD) and diabetes risk and whether it varies by ethnicity. RESEARCH DESIGN AND METHODS:We performed an analysis of data from participants who attended the morning examination of the Third National Health and Nutrition Examination Survey (1988-...

journal_title：Diabetes care

authors： Scragg R,Sowers M,Bell C,Third National Health and Nutrition Examination Survey.

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Foot ulceration is a serious complication of diabetes, and new techniques that can predict wound healing may prove very helpful. We tested the ability of medical hyperspectral technology (HT), a novel diagnostic scanning technique that can quantify tissue oxy- and deoxyhemoglobin to predict diabetic foot ulce...

journal_title：Diabetes care

authors： Khaodhiar L,Dinh T,Schomacker KT,Panasyuk SV,Freeman JE,Lew R,Vo T,Panasyuk AA,Lima C,Giurini JM,Lyons TE,Veves A

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA). RESEARCH DESIGN AND METHODS:The CGMS enabled recording of subcutaneous g...

journal_title：Diabetes care

authors： Kessler L,Passemard R,Oberholzer J,Benhamou PY,Bucher P,Toso C,Meyer P,Penfornis A,Badet L,Wolf P,Colin C,Morel P,Pinget M,GRAGIL Group.

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Recent studies have drawn attention to the adverse effects of ambient air pollutants such as particulate matter 2.5 (PM2.5) on human health. We evaluated the association between PM2.5 exposure and diabetes prevalence in the U.S. and explored factors that may influence this relationship. RESEARCH DESIGN AND M...

journal_title：Diabetes care

authors： Pearson JF,Bachireddy C,Shyamprasad S,Goldfine AB,Brownstein JS

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:There is suggestive evidence linking hypoglycemia with cardiovascular disease, but few data have been collected in a community-based setting. Information is lacking on individual cardiovascular outcomes and cause-specific mortality. RESEARCH DESIGN AND METHODS:We conducted a prospective cohort analysis of 1,...

journal_title：Diabetes care

authors： Lee AK,Warren B,Lee CJ,McEvoy JW,Matsushita K,Huang ES,Sharrett AR,Coresh J,Selvin E

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Monozygotic twins are usually discordant (only one twin affected) for type 1 diabetes. Discordance for disease between such twins implies a role for nongenetically determined factors but could also be influenced by a decreased load of diabetes susceptibility genes. The aim of this study was to determine wheth...

journal_title：Diabetes care

authors： Metcalfe KA,Hitman GA,Rowe RE,Hawa M,Huang X,Stewart T,Leslie RD

更新日期：2001-05-01 00:00:00

abstract：:OBJECTIVE We tested whether average monthly glycemic burden (AMGB), a marker of hyperglycemia that is a function of the extent and duration that A1C exceeded 7%, indicated greater risk of cardiovascular disease (CVD) than traditional A1C measures. RESEARCH DESIGN AND METHODS Using a case-control design, we studied 2,4...

journal_title：Diabetes care

authors： Nichols GA,Rosales AG,Perrin NA,Fortmann SP

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Insulin analogs are increasingly used in patients with type 2 diabetes. We compared the effect of basal, biphasic, prandial, and basal-bolus insulin regimens with insulin analogs to reach the hemoglobin A(1c) (HbA(1c)) target of <7% in people with type 2 diabetes. RESEARCH DESIGN AND METHODS:We conducted an ...

journal_title：Diabetes care

authors： Giugliano D,Maiorino MI,Bellastella G,Chiodini P,Ceriello A,Esposito K

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To compare the diagnostic properties of a nonmydriatic 200° ultra-widefield scanning laser ophthalmoscope (SLO) versus mydriatic Early Treatment of Diabetic Retinopathy Study (ETDRS) 7-field photography for diabetic retinopathy (DR) screening. RESEARCH DESIGN AND METHODS:A consecutive series of 212 eyes of 1...

journal_title：Diabetes care

authors： Kernt M,Hadi I,Pinter F,Seidensticker F,Hirneiss C,Haritoglou C,Kampik A,Ulbig MW,Neubauer AS

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Plasma leptin, an important signal for the regulation of energy stores, is known to be influenced by many hormonal factors, but may also be affected by behavioral and environmental factors. The purpose of this study was to investigate the impact of lifestyle (diet composition, level of physical activity) on p...

journal_title：Diabetes care

authors： Fox C,Esparza J,Nicolson M,Bennett PH,Schulz LO,Valencia ME,Ravussin E

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To investigate the triglyceride-glucose (TyG) index association with coronary artery calcification (CAC) progression in adult Koreans. RESEARCH DESIGN AND METHODS:Various cardiovascular risk factors and anthropometric profiles were assessed in 1,175 subjects who previously had a CAC evaluation at least twice...

journal_title：Diabetes care

authors： Park K,Ahn CW,Lee SB,Kang S,Nam JS,Lee BK,Kim JH,Park JS

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes has been associated with factors related to welfare and social class. During the past decade, Lithuania has experienced a transition period, leading to dramatic changes in the socioeconomic structure of the society. RESEARCH DESIGN AND METHODS:Incidence in the group aged 0-39 years by urban-r...

journal_title：Diabetes care

authors： Pundziute-Lyckå A,Urbonaite B,Ostrauskas R,Zalinkevicius R,Dahlquist GG

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Gestational diabetes mellitus (GDM) is an increasingly prevalent risk factor for the development of type 2 diabetes in the mother and is responsible for morbidity in the child. To better identify women at risk of developing GDM we examined sociodemographic correlates and changes in the prevalence of GDM among...

journal_title：Diabetes care

authors： Anna V,van der Ploeg HP,Cheung NW,Huxley RR,Bauman AE

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To investigate 1-year outcomes of a national diabetes prevention program in Finland. RESEARCH DESIGN AND METHODS:Altogether 10,149 individuals at high risk for diabetes were identified with the Finnish Diabetes Risk Score (FINDRISC; scoring ≥15 points), by a history of impaired fasting glucose (IFG) or impai...

journal_title：Diabetes care

authors： Saaristo T,Moilanen L,Korpi-Hyövälti E,Vanhala M,Saltevo J,Niskanen L,Jokelainen J,Peltonen M,Oksa H,Tuomilehto J,Uusitupa M,Keinänen-Kiukaanniemi S

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Prior studies have supported that waist circumference correlates better with visceral adipose tissue and is a better predictor of cardiovascular disease than are BMI and waist-to-hip ratio. In this study, we reexamine the role of waist size on the risk of hypertension and type 2 diabetes in African-origin pop...

journal_title：Diabetes care

authors： Okosun IS,Cooper RS,Rotimi CN,Osotimehin B,Forrester T

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To assess effectiveness of inpatient hybrid closed-loop control (HCLC) followed by outpatient sensor-augmented pump (SAP) therapy initiated within 7 days of diagnosis of type 1 diabetes on the preservation of β-cell function at 1 year. RESEARCH DESIGN AND METHODS:Sixty-eight individuals (mean age 13.3 ± 5.7 ...

journal_title：Diabetes care

authors： Buckingham B,Beck RW,Ruedy KJ,Cheng P,Kollman C,Weinzimer SA,DiMeglio LA,Bremer AA,Slover R,Tamborlane WV,Diabetes Research in Children Network (DirecNet) Study Group.,Type 1 Diabetes TrialNet Study Group.

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:Reports of amputations associated with sodium-glucose cotransporter 2 (SGLT2) inhibitors have been inconsistent. We aimed to compare the risk of below-knee amputation with SGLT2 inhibitors versus dipeptidyl peptidase 4 (DPP-4) inhibitors among patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:This m...

journal_title：Diabetes care

authors： Yu OHY,Dell'Aniello S,Shah BR,Brunetti VC,Daigle JM,Fralick M,Douros A,Hu N,Alessi-Severini S,Fisher A,Bugden SC,Ronksley PE,Filion KB,Ernst P,Lix LM,Canadian Network for Observational Drug Effect Studies (CNODES) Investiga

更新日期：2020-10-01 00:00:00