Concordance for type 1 diabetes in identical twins is affected by insulin genotype.

abstract：OBJECTIVE:The objective of this study was to evaluate the short-term impact of a 7-h type 2 diabetes continuing medical education (CME) program. Outcomes included a measure of health care providers' diabetes knowledge and the Diabetes Attitude Scale (DAS), a validated measure of attitudes toward diabetes. RESEARCH DES...

journal_title：Diabetes care

authors： Sharp LK,Lipsky MS

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:The association between changes in triglyceride concentrations over time and diabetes is unknown. We assessed whether two triglyceride determinations obtained 5 years apart can predict incident type 2 diabetes. RESEARCH DESIGN AND METHODS:Triglyceride levels at baseline (time 1) and 5 years later (time 2), f...

journal_title：Diabetes care

authors： Tirosh A,Shai I,Bitzur R,Kochba I,Tekes-Manova D,Israeli E,Shochat T,Rudich A

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and relative risk of type 2 diabetes defined by the newly proposed HbA(1c) diagnostic criteria in groups categorized by different baseline HbA(1c) levels. RESEARCH DESIGN AND METHODS:Using data from the European Prospective Investigation of Cancer (EPIC)-Norfolk cohort with repeat H...

journal_title：Diabetes care

authors： Chamnan P,Simmons RK,Forouhi NG,Luben RN,Khaw KT,Wareham NJ,Griffin SJ

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the accuracy of the UK Prospective Diabetes Study Outcomes Model (UKPDS-OM) in predicting clinical outcomes during the UKPDS posttrial monitoring (PTM) period. RESEARCH DESIGN AND METHODS:At trial end in 1997, the 4,031 surviving UKPDS patients, of the 5,102 originally enrolled in the study, retu...

journal_title：Diabetes care

authors： Leal J,Hayes AJ,Gray AM,Holman RR,Clarke PM

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Patients with diabetes due to hepatocyte nuclear factor (HNF)-1alpha mutations have beta-cell deficiency, insulin sensitivity, altered proinsulin levels, and a low renal threshold for glucose. It is uncertain how many of these features precede the development of diabetes. The aim of our study was to test for ...

journal_title：Diabetes care

authors： Stride A,Ellard S,Clark P,Shakespeare L,Salzmann M,Shepherd M,Hattersley AT

更新日期：2005-07-01 00:00:00

abstract：:A major problem in replacing insulin in type I diabetes mellitus is that currently no depot preparation exists that is capable of mimicking the background insulin secretion of the healthy pancreas. Because all of the currently available intermediate- or long-acting insulin preparations have a peaked-action profile, ex...

journal_title：Diabetes care

authors： Bolli GB,Perriello G,Fanelli CG,De Feo P

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:To explore the possible link between diabetic nephropathy and the enhanced activity of the polyol pathway, known to occur in IDDM subjects. RESEARCH DESIGN AND METHODS:We studied the effects of the aldose reductase inhibitor tolrestat (200 mg/day) on urinary albumin excretion rate and glomerular filtration r...

journal_title：Diabetes care

authors： Passariello N,Sepe J,Marrazzo G,De Cicco A,Peluso A,Pisano MC,Sgambato S,Tesauro P,D'Onofrio F

更新日期：1993-05-01 00:00:00

abstract：:Enzymatic electrodes are described for the specific and sensitive determination of glucose in blood. The probes are based on the conversion of B-D-glucose by glucose oxidase chemically attached to the surface of a Pt electrode. The peroxide liberated is sensed by measurement of the current generated at +0.7 volts vs. ...

journal_title：Diabetes care

authors： Guilbault GG

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:To evaluate statin use in the U.S. before and after the 2015 American Diabetes Association position statement, which expanded statin therapy recommendations to include all adults 40-75 years old with diabetes. RESEARCH DESIGN AND METHODS:The National Health and Nutrition Examination Survey (NHANES) was used ...

journal_title：Diabetes care

authors： Leino AD,Dorsch MP,Lester CA

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, stimulates glycosuria and lowers glycemia in patients with type 2 diabetes (T2DM). The objective of this study was to assess the pharmacodynamics of ipragliflozin in T2DM patients with impaired renal function. RESEARCH DESIGN AND METHODS:Glycosuria w...

journal_title：Diabetes care

authors： Ferrannini E,Veltkamp SA,Smulders RA,Kadokura T

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Assessing updated incidence of type 1 diabetes in 0- to 14-year-old children in Liguria, a Northwest region of Italy. RESEARCH DESIGN AND METHODS:Incident cases were recorded prospectively from 1989 to 1998. Incidence rates (IRs) were standardized to the 1999 world population using the direct method. The ind...

journal_title：Diabetes care

authors： Cotellessa M,Barbieri P,Mazzella M,Bonassi S,Minicucci L,Lorini R

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To quantify the impact of diabetes status on healthy and disabled years of life for older adults in the U.S. and provide a baseline from which to evaluate ongoing national public health efforts to prevent and control diabetes and disability. RESEARCH DESIGN AND METHODS:Adults (n = 20,008) aged 50 years and o...

journal_title：Diabetes care

authors： Bardenheier BH,Lin J,Zhuo X,Ali MK,Thompson TJ,Cheng YJ,Gregg EW

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:Gestational diabetes mellitus has been associated with offspring cardiac congenital malformations, ventricular hypertrophy, and diastolic dysfunction in large observational cohort studies and experimental animal models. We assessed the associations of maternal random glucose concentrations across the full ran...

journal_title：Diabetes care

authors： Wahab RJ,Jaddoe VWV,Roest AAW,Toemen L,Gaillard R

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Of patients who are prescribed metformin, 10-30% have evidence of reduced vitamin B12 absorption. B12-intrinsic factor complex uptake by ileal cell surface receptors is known to be a process dependent on calcium availability Metformin affects calcium-dependent membrane action. The objective of this study was ...

journal_title：Diabetes care

authors： Bauman WA,Shaw S,Jayatilleke E,Spungen AM,Herbert V

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To determine the value of measuring serum triglyceride (TG) levels early in pregnancy for predicting late-gestation glucose tolerance and neonatal birth weight ratio (BWR) (birth weight corrected for gestational age). RESEARCH DESIGN AND METHODS:The relationships between morning nonfasting TG measured early ...

journal_title：Diabetes care

authors： Nolan CJ,Riley SF,Sheedy MT,Walstab JE,Beischer NA

更新日期：1995-12-01 00:00:00

abstract：:Diabetes mellitus is a major public health problem and a leading cause of death, disability, and cost in the United States. We review the epidemiology of diabetes and its complications, the costs of diabetes, and discuss intervention strategies to reduce the burden of diabetes in the United States. ...

journal_title：Diabetes care

authors：

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:To improve prognosis, it is important to predict the incidence of renal failure and cardiovascular disease in type 2 diabetic patients before the progression to advanced nephropathy. We investigated the predictive effects of urinary liver-type fatty acid-binding protein (L-FABP), which is associated with rena...

journal_title：Diabetes care

authors： Araki S,Haneda M,Koya D,Sugaya T,Isshiki K,Kume S,Kashiwagi A,Uzu T,Maegawa H

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To estimate the health-related quality of life (HRQOL) and treatment satisfaction for patients with type 2 diabetes in the Netherlands and to examine which patient characteristics are associated with quality of life and treatment satisfaction. RESEARCH DESIGN AND METHODS:For a sample of 1,348 type 2 diabetes...

journal_title：Diabetes care

authors： Redekop WK,Koopmanschap MA,Stolk RP,Rutten GE,Wolffenbuttel BH,Niessen LW

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence of beta-cell autoantigen-reactive peripheral T-cells in type 1 diabetes, we developed an immunoglobulin-free enzyme-linked immunospot (ELISPOT) assay and assessed its usefulness for diagnosing this disease. RESEARCH DESIGN AND METHODS:Cellular immune responses to beta -cell auto...

journal_title：Diabetes care

authors： Kotani R,Nagata M,Moriyama H,Nakayama M,Yamada K,Chowdhury SA,Chakrabarty S,Jin Z,Yasuda H,Yokono K

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate alcohol consumption in relation to the incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS:The study population consisted of 22778 twins of the Finnish Twin Cohort. This cohort was compiled in 1975 and includes all same-sexed twins born in Finland before 1958. I...

journal_title：Diabetes care

authors： Carlsson S,Hammar N,Grill V,Kaprio J

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:We evaluated the safety and efficacy of day-and-night fully closed-loop insulin therapy using faster (Faster-CL) compared with standard insulin aspart (Standard-CL) in young adults with type 1 diabetes. RESEARCH DESIGN AND METHODS:In a double-blind, randomized, crossover trial, 20 participants with type 1 di...

journal_title：Diabetes care

authors： Dovc K,Piona C,Yeşiltepe Mutlu G,Bratina N,Jenko Bizjan B,Lepej D,Nimri R,Atlas E,Muller I,Kordonouri O,Biester T,Danne T,Phillip M,Battelino T

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:HER2/ErbB2 is a member of the epidermal growth factor receptor family. It is widely used as a tumor marker, but it also has recently been associated with insulin resistance. Both ErbB2 and diabetes have been associated with cancer; however, the relationship between ErbB2 and diabetes has not been well explore...

journal_title：Diabetes care

authors： Muhammad IF,Borné Y,Bao X,Melander O,Orho-Melander M,Nilsson PM,Nilsson J,Engström G

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVES:Obesity is a common condition in type 2 diabetic patients. Treating obesity may enhance hypoglycemic treatment and contribute to the reduction of long-term microvascular and macrovascular complications. Orlistat reduces cardiovascular risk factors in obese type 2 diabetic patients. The objectives of this stu...

journal_title：Diabetes care

authors： Lamotte M,Annemans L,Lefever A,Nechelput M,Masure J

更新日期：2002-02-01 00:00:00

abstract：:Urinary albumin excretion rate (radial immunodiffusion), glomerular filtration rate (GFR) (single-shot 51Cr-EDTA technique), and arterial blood pressure (BP) were measured in 12 juvenile-onset, insulin-dependent diabetic patients with persistent proteinuria (greater than 0.5 g/day) due to diabetic nephropathy. Mean ag...

journal_title：Diabetes care

authors： Parving HH,Andersen AR,Smidt UM,Friisberg B,Svendsen PA

更新日期：1981-07-01 00:00:00

abstract：:Intensive insulin therapy is best defined as a comprehensive system of diabetes management with the patient and management team as partners. The system is directed at improvement of glycemia and patient well-being. Glycemic targets should be individually defined. Frequent self-monitoring of blood glucose, probably at ...

journal_title：Diabetes care

authors： Hirsch IB,Farkas-Hirsch R,Skyler JS

更新日期：1990-12-01 00:00:00

abstract：:Increasingly more tests are being used to detect and characterize diabetic polyneuropathy, but their value in setting minimal criteria for the diagnosis of neuropathy and for staging severity remains inadequately studied. In 180 diabetics, we compared the percentage of patients with test abnormalities and associations...

journal_title：Diabetes care

authors： Dyck PJ,Bushek W,Spring EM,Karnes JL,Litchy WJ,O'Brien PC,Service FJ

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVE:To determine if nephropathy in NIDDM is associated with cellular markers for hypertension. RESEARCH DESIGN AND METHODS:We compared 11 patients with clinical diabetic nephropathy with 15 control subjects with no diabetic nephropathy. The patients were white and had had NIDDM for > or = 9 yr and serum creatini...

journal_title：Diabetes care

authors： Herman WH,Prior DE,Yassine MD,Weder AB

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To compare recent U.S. and U.K. guidelines on gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:The guidelines from the American Diabetes Association, the American College of Obstetricians and Gynecologists, and the National Institute for Health and Clinical Excellence (NICE) in the U.K. were ...

journal_title：Diabetes care

authors： Simmons D,McElduff A,McIntyre HD,Elrishi M

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The effect of a healthy lifestyle on diabetes-related dementia remains unknown. We examined whether an active lifestyle and rich social network may counteract the increased risk of dementia in people with diabetes. RESEARCH DESIGN AND METHODS:Dementia-free older adults from the Swedish National Study on Agin...

journal_title：Diabetes care

authors： Marseglia A,Wang HX,Rizzuto D,Fratiglioni L,Xu W

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:We sought to study the prevalence of autoantibodies to various islet cell antigens in the background population of two neighboring countries with a sixfold difference in the incidence of type 1 diabetes. RESEARCH DESIGN AND METHODS:Serum samples were obtained from 3,652 nondiabetic schoolchildren in Finland ...

journal_title：Diabetes care

authors： Kondrashova A,Viskari H,Kulmala P,Romanov A,Ilonen J,Hyöty H,Knip M

更新日期：2007-01-01 00:00:00