Changes in inflammatory cytokines are related to impaired glucose tolerance in offspring of type 2 diabetic subjects.

abstract：OBJECTIVE:Little is known about medial arterial calcification (MAC) other than its association with age, sex, diabetes, and diabetes complications. Familial aggregation of this disorder was studied to determine the importance of potential genetic factors and to assess whether such familial aggregation was independent o...

journal_title：Diabetes care

authors： Narayan KM,Pettitt DJ,Hanson RL,Bennett PH,Fernandes RJ,De Courten M,Rose FA,Knowler WC

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:Epidemiological studies and randomized clinical trials have demonstrated in various populations that resting heart rate (RHR) was an independent predictor of cardiovascular (CV) risk and all-cause mortality. However, few data specifically evaluated the relationship between RHR and long-term CV and renal compl...

journal_title：Diabetes care

authors： Miot A,Ragot S,Hammi W,Saulnier PJ,Sosner P,Piguel X,Torremocha F,Marechaud R,Hadjadj S

更新日期：2012-10-01 00:00:00

abstract：:Specialists in childhood diabetes in North America were queried about the need for residential facilities for their patients with recurrent hospitalizations and school deficits due to family coping problems. Of 132 respondents, 115 indicated a need for 5-12% of their patients, a total of 530, close to the estimate of ...

journal_title：Diabetes care

authors： Rosenbloom AL

更新日期：1982-09-01 00:00:00

abstract：OBJECTIVE:This study evaluated the ability of the Building, Relating, Assessing, and Validating Outcomes (BRAVO) risk engine to accurately project cardiovascular outcomes in three major clinical trials-BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME), C...

journal_title：Diabetes care

authors： Shao H,Shi L,Fonseca VA

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Gestational diabetes mellitus has been associated with offspring cardiac congenital malformations, ventricular hypertrophy, and diastolic dysfunction in large observational cohort studies and experimental animal models. We assessed the associations of maternal random glucose concentrations across the full ran...

journal_title：Diabetes care

authors： Wahab RJ,Jaddoe VWV,Roest AAW,Toemen L,Gaillard R

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:We have demonstrated high heritability of insulin secretion measured as acute insulin response to glucose times insulin sensitivity (disposition index). Furthermore, we showed that obese normoglycemic family members of a type 2 diabetic proband failed to compensate for the insulin resistance of obesity by inc...

journal_title：Diabetes care

authors： Elbein SC,Sun J,Scroggin E,Teng K,Hasstedt SJ

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To investigate the dose-response effects of pioglitazone on glycemic control, insulin sensitivity, and insulin secretion in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 58 diet-treated patients with type 2 diabetes (aged 54 +/- 1 years; 34 men and 24 women; BMI 31.5 +/- 0.6 kg/m(2)) ...

journal_title：Diabetes care

authors： Miyazaki Y,Matsuda M,DeFronzo RA

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Insulin resistance (IR) and the metabolic syndrome (MS) are associated with type 2 diabetes and adverse cardiovascular disease (CVD) risk factor profiles. Whether IR and MS predict CVD independently of diabetes and other CVD risk factors is not known. This study examines whether IR and/or presence of MS are i...

journal_title：Diabetes care

authors： Resnick HE,Jones K,Ruotolo G,Jain AK,Henderson J,Lu W,Howard BV,Strong Heart Study.

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:We evaluated the accuracy and stability of a capillary HbA1c collection system for use with a high-performance liquid chromatography analyzer. RESEARCH DESIGN AND METHODS:The collection system requires that 5 ul blood is drawn into a calibrated capillary tube, which is then placed into a vial of stabilizing ...

journal_title：Diabetes care

authors： Voss EM,Cembrowski GS,Clasen BL,Spencer ML,Ainslie MB,Haig B

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:In 2010, the American Diabetes Association (ADA) added hemoglobin A1c (A1C) to the guidelines for diagnosing type 2 diabetes. However, existing models for predicting diabetes risk were developed prior to the widespread adoption of A1C. Thus, it remains unknown how well existing diabetes risk prediction models...

journal_title：Diabetes care

authors： Lacy ME,Wellenius GA,Carnethon MR,Loucks EB,Carson AP,Luo X,Kiefe CI,Gjelsvik A,Gunderson EP,Eaton CB,Wu WC

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:To examine by meta-analysis the relationship between cardiovascular autonomic neuropathy (CAN) and risk of mortality in individuals with diabetes. RESEARCH DESIGN AND METHODS:We searched Medline for English-language articles published from 1966 to 2001. Fifteen studies having a baseline assessment of cardiov...

journal_title：Diabetes care

authors： Maser RE,Mitchell BD,Vinik AI,Freeman R

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:This study compared heart rate variability (HRV) parameters in youth with and without type 1 diabetes and explored potential contributors of altered HRV. RESEARCH DESIGN AND METHODS:HRV parameters were measured among 354 youth with type 1 diabetes (mean age 18.8 years, diabetes duration 9.8 years, and mean A...

journal_title：Diabetes care

authors： Jaiswal M,Urbina EM,Wadwa RP,Talton JW,D'Agostino RB Jr,Hamman RF,Fingerlin TE,Daniels S,Marcovina SM,Dolan LM,Dabelea D

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Depression is common in patients with type 2 diabetes and adversely affects quality of life and diabetes outcomes. We assessed whether light therapy, an antidepressant, improves mood and insulin sensitivity in patients with depression and type 2 diabetes. RESEARCH DESIGN AND METHODS:This randomized, double-b...

journal_title：Diabetes care

authors： Brouwer A,van Raalte DH,Nguyen HT,Rutters F,van de Ven PM,Elders PJM,Moll AC,Van Someren EJW,Snoek FJ,Beekman ATF,Bremmer MA

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:In a few previous studies, cardiovascular disease (CVD) risk factors (RFs) have been shown to predict diabetes. Our objective was to determine whether the presence of CVD RFs predict the eventual development of diabetes after controlling for known RFs, such as directly measured insulin resistance and obesity....

journal_title：Diabetes care

authors： D'Agostino RB Jr,Hamman RF,Karter AJ,Mykkanen L,Wagenknecht LE,Haffner SM,Insulin Resistance Atherosclerosis Study Investigators.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To determine whether evidence-based socioculturally adapted collaborative depression care improves receipt of depression care and depression and diabetes outcomes in low-income Hispanic subjects. RESEARCH DESIGN AND METHODS:This was a randomized controlled trial of 387 diabetic patients (96.5% Hispanic) with...

journal_title：Diabetes care

authors： Ell K,Katon W,Xie B,Lee PJ,Kapetanovic S,Guterman J,Chou CP

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the role of adiposity in the relationship between specific and surrogate estimates of insulin-mediated glucose uptake (IMGU) in a large nondiabetic population. RESEARCH DESIGN AND METHODS:Healthy volunteers were classified by BMI into normal weight (<25.0 kg/m(2), n = 208), overweight (25.0-29.9 ...

journal_title：Diabetes care

authors： Kim SH,Abbasi F,Reaven GM

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To determine the incidence of insulin-dependent diabetes mellitus (IDDM) in children aged 0-14 years in Kuwait, as part of the World Health Organization Multinational Collaborative Study (DIAMOND), and to determine if the incidence rates have increased. RESEARCH DESIGN AND METHODS:All cases of IDDM diagnosed...

journal_title：Diabetes care

authors： Shaltout AA,Qabazard MA,Abdella NA,LaPorte RE,al Arouj M,Ben Nekhi A,Moussa MA,al Khawari MA

更新日期：1995-07-01 00:00:00

abstract：:The results of uncontrolled trials in immunomodulation of insulin-dependent diabetes mellitus (IDDM) led to randomized controlled trials in Canada and Europe. In the Canadian open study, the rate of clinical remissions (target control of glycemia maintained with less than or equal to 0.15 U.kg-1.day-1 insulin) was une...

journal_title：Diabetes care

authors： Dupré J,Stiller CR,Gent M,Donner A,von Graffenried B,Heinrichs D,Jenner M,Keown P,Mahon J,Martell R

更新日期：1988-11-01 00:00:00

abstract：:This study examined the effect of age on the posthepatic delivery of oral glucose (PHDG) during steady-state conditions. We used an intravenous-oral modification of the euglycemic insulin-clamp technique to assess PHDG in six men aged 24-39 yr (young) and eight men aged 65-83 yr (old). Each subject underwent two studi...

journal_title：Diabetes care

authors： Tonino RP,Minaker KL,Rowe JW

更新日期：1989-06-01 00:00:00

abstract：:Use of continuous subcutaneous insulin infusion requires continuing available care by skilled professionals, careful selection of patients, meticulous patient monitoring, and provisions for recording and reporting experiences. Insulin pumps prescribed by a physician within these guidelines are a part of treatment and ...

journal_title：Diabetes care

authors：

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:Diabetic patients have a high prevalence of coronary artery disease (CAD), but timely diagnosis of CAD remains challenging. We assessed the ability of coronary computed tomography angiography (CCTA) to detect CAD in diabetic patients and to predict subsequent cardiac events. RESEARCH DESIGN AND METHODS:We an...

journal_title：Diabetes care

authors： Hadamitzky M,Hein F,Meyer T,Bischoff B,Martinoff S,Schömig A,Hausleiter J

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To test the utility of homeostasis model assessment (HOMA) in predicting insulin sensitivity [x10(- 4) min(-1)/(microIU/ml)] in children and to develop and compare two new prediction equations for insulin sensitivity in children using demographic and anthropometric measures in the presence or absence of fasti...

journal_title：Diabetes care

authors： Huang TT,Johnson MS,Goran MI

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of new insulin glargine 300 units/mL (Gla-300) with glargine 100 units/mL (Gla-100) in people with type 2 diabetes on basal insulin (≥42 units/day) plus mealtime insulin. RESEARCH DESIGN AND METHODS:EDITION 1 (NCT01499082) was a 6-month, multinational, open-label, parallel-...

journal_title：Diabetes care

authors： Riddle MC,Bolli GB,Ziemen M,Muehlen-Bartmer I,Bizet F,Home PD,EDITION 1 Study Investigators.

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The present study was designed to assess the effect of magnesium plus zinc, vitamins C plus E, and a combination of these micronutrients on nephropathy indexes in type 2 diabetic patients. RESEARCH DESIGN AND METHODS:In a randomized, double-blind, placebo-controlled clinical trial, 69 type 2 diabetic patient...

journal_title：Diabetes care

authors： Farvid MS,Jalali M,Siassi F,Hosseini M

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine medication adherence and other self-management practices as potential determinants of higher glycemic risk among black relative to white patients. RESEARCH DESIGN AND METHODS:We used a retrospective, longitudinal repeated-measures design to model the contribution of m...

journal_title：Diabetes care

authors： Adams AS,Trinacty CM,Zhang F,Kleinman K,Grant RW,Meigs JB,Soumerai SB,Ross-Degnan D

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To evaluate weight loss and cardiometabolic risk reduction achieved through an adapted Diabetes Prevention Program intervention among adults at high risk for cardiovascular disease (CVD) and diabetes. RESEARCH DESIGN AND METHODS:Eight health care facilities implemented a group-based lifestyle intervention be...

journal_title：Diabetes care

authors： Vanderwood KK,Hall TO,Harwell TS,Butcher MK,Helgerson SD,Montana Cardiovascular Disease and Diabetes Prevention Program Workgroup.

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To estimate the cost-effectiveness of surgically induced weight loss relative to conventional therapy for the management of recently diagnosed type 2 diabetes in class I/II obese patients. RESEARCH DESIGN AND METHODS:This study builds on a within-trial cost-efficacy analysis. The analysis compares the lifeti...

journal_title：Diabetes care

authors： Keating CL,Dixon JB,Moodie ML,Peeters A,Bulfone L,Maglianno DJ,O'Brien PE

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To evaluate effects of vildagliptin and metformin on blood pressure (BP) and heart rate (HR) responses to intraduodenal (ID) glucose in diet-controlled type 2 diabetes. RESEARCH DESIGN AND METHODS:Study A compared vildagliptin (50 mg) and placebo, given 60 min before a 120-min ID glucose infusion at 2 or 4 k...

journal_title：Diabetes care

authors： Wu T,Trahair LG,Little TJ,Bound MJ,Zhang X,Wu H,Sun Z,Horowitz M,Rayner CK,Jones KL

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Pediatric type 2 diabetes prevalence is increasing, with β-cell dysfunction key in its pathogenesis. The RISE Pediatric Medication Study compared two approaches-glargine followed by metformin and metformin alone-in preserving or improving β-cell function in youth with impaired glucose tolerance (IGT) or recen...

journal_title：Diabetes care

authors： RISE Consortium.

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To develop an instrument to measure health status in adult insulin-dependent (type I) and non-insulin-dependent (type II) diabetic patients. RESEARCH DESIGN AND METHODS:Correlative study to examine psychometric properties of the questionnaire. Test-retest reliability, item-scale correlations, principal-compo...

journal_title：Diabetes care

authors： Hammond GS,Aoki TT

更新日期：1992-04-01 00:00:00