Effects of Vildagliptin and Metformin on Blood Pressure and Heart Rate Responses to Small Intestinal Glucose in Type 2 Diabetes.

abstract：:A survey of the entire population of Israel revealed 392 newly diagnosed type I diabetic children and adolescents aged 0-20 for the period of 1975-80. The mean annual age specific incidence of type I (insulin-dependent) diabetes mellitus was 3.8/10(5) for the age group 0-14 yr and 4.2/10(5) for the age group 0-20 yr. ...

journal_title：Diabetes care

authors： Laron ZV,Karp M,Modan M

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:We aimed at analyzing the frequency, clinical characteristics, and trends associated with the occurrence of diabetic ketoacidosis (DKA) at the onset of type 1 diabetes on the basis of long-term follow-up data. RESEARCH DESIGN AND METHODS:A total of 106 pediatric diabetes centers in Germany and Austria partic...

journal_title：Diabetes care

authors： Neu A,Hofer SE,Karges B,Oeverink R,Rosenbauer J,Holl RW,DPV Initiative and the German BMBF Competency Network for Diabetes Mellitus.

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To compare three continuous glucose monitoring (CGM) devices in subjects with type 1 diabetes under closed-loop blood glucose (BG) control. RESEARCH DESIGN AND METHODS:Six subjects with type 1 diabetes (age 52 ± 14 years, diabetes duration 32 ± 14 years) each participated in two 51-h closed-loop BG control e...

journal_title：Diabetes care

authors： Damiano ER,El-Khatib FH,Zheng H,Nathan DM,Russell SJ

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:The mechanisms by which diabetes leads to rapidly progressive atherosclerosis are not fully understood. Adherence of monocytes to the arterial wall is an early event in the development of atherosclerotic lesions. RESEARCH DESIGN AND METHODS:The binding of freshly isolated monocytes from patients with NIDDM, ...

journal_title：Diabetes care

authors： Hoogerbrugge N,Verkerk A,Jacobs ML,Postema PT,Jongkind JF

更新日期：1996-10-01 00:00:00

abstract：:Natriuretic peptides (NPs) play a key role in cardiovascular homeostasis, counteracting the deleterious effects of volume and pressure overload and activating antibrotic and antihypertrophic pathways in the heart. N-terminal B-type NP (NT-proBNP) also is a promising biomarker of global cardiovascular risk in the gener...

journal_title：Diabetes care

authors： Gruden G,Landi A,Bruno G

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To compare a simple meal plan emphasizing healthy food choices with a traditional exchange-based meal plan in reducing HbA(1c) levels in urban African Americans with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 648 patients with type 2 diabetes were randomized to receive instruction in either a he...

journal_title：Diabetes care

authors： Ziemer DC,Berkowitz KJ,Panayioto RM,El-Kebbi IM,Musey VC,Anderson LA,Wanko NS,Fowke ML,Brazier CW,Dunbar VG,Slocum W,Bacha GM,Gallina DL,Cook CB,Phillips LS

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:Diabetes is the leading cause of nontraumatic lower-limb amputations in the U.S., but no research has prospectively examined associations between limb-specific measurements and amputation risk among patients without foot ulcer. We investigated amputation risk by limb in relation to the same limb- and person-l...

journal_title：Diabetes care

authors： Boyko EJ,Seelig AD,Ahroni JH

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To determine the effect of diabetes on thyroid hormone and thyroxine-binding globulin (TBG) concentrations during puberty. RESEARCH DESIGN AND METHODS:Total thyroxine (TT4), free thyroxine (FT4), and TBG levels of 171 thyroid microsomal antibody-negative subjects with normal thyroid-stimulating hormone (TSH)...

journal_title：Diabetes care

authors： Connors MH,Dunger DB,Chapel H,Jefferson I,Jowett TP,Edwards PR

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of an intervention program designed to improve blood glucose awareness. RESEARCH DESIGN AND METHODS:Eight young-adult outpatients (mean age 22 yr) and six adolescent inpatients (mean age 14.5 yr) with insulin-dependent diabetes mellitus participated in the intervention program....

journal_title：Diabetes care

authors： Nurick MA,Johnson SB

更新日期：1991-01-01 00:00:00

abstract：:A rapid paper-strip test for the semiquantitating 3-hydroxybutyrate (3-OHBA) has been developed. The color develops within 5 min after applying the serum to the paper strip, and the purple color was read either visually or by reflectance meter. This can detect 3-OHBA levels as low as 0.1 mmol/L up to 2.0 mmol/L. The m...

journal_title：Diabetes care

authors： Harano Y,Suzuki M,Kojima H,Kashiwagi A,Hidaka H,Shigeta Y

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the prevalence of both impaired fasting glucose (IFG) and diabetes between hepatitis C virus (HCV)-infected patients and patients with other liver diseases but anti-HCV-, taking into account the degree of liver damage. RESEARCH DESIGN AND METHODS:A total of 642 consecutiv...

journal_title：Diabetes care

authors： Lecube A,Hernández C,Genescà J,Esteban JI,Jardí R,Simó R

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:In cross-sectional studies of subjects with IDDM, the relationship between suboptimal pubertal growth, glycemic control, and abnormal insulin-like growth factor I (IGF-I) levels has proved difficult to define. The objective of this study was to examine these relationships in a longitudinal prospective study. ...

journal_title：Diabetes care

authors： Ahmed ML,Connors MH,Drayer NM,Jones JS,Dunger DB

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:Among postmenopausal women, those with diabetes experience more cardiovascular diseases than those without diabetes. We examine the relationship of hormone replacement therapy (HRT) with indicators of lipid and glucose metabolism using a national sample of diabetic and nondiabetic postmenopausal women. RESEA...

journal_title：Diabetes care

authors： Crespo CJ,Smit E,Snelling A,Sempos CT,Andersen RE,NHANES III.

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that lower vital capacity is cross-sectionally associated with features of insulin resistance and is an independent predictor of incident type 2 diabetes. RESEARCH DESIGN AND METHODS:We conducted a prospective cohort study of vital capacity as a predictor of incident type 2 diabetes us...

journal_title：Diabetes care

authors： Yeh HC,Punjabi NM,Wang NY,Pankow JS,Duncan BB,Brancati FL

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence of NIDDM and IGT in the urban and rural areas in southern India. RESEARCH DESIGN AND METHODS:Two populations of the same ethnic background, but different socioeconomic background were chosen for this study. Nine-hundred urban people and 1038 rural subjects were studied. Fasting and...

journal_title：Diabetes care

authors： Ramachandran A,Snehalatha C,Dharmaraj D,Viswanathan M

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:A genetic risk score (GRS) comprised of single nucleotide polymorphisms (SNPs) and metabolite biomarkers have each been shown, separately, to predict incident type 2 diabetes. We tested whether genetic and metabolite markers provide complementary information for type 2 diabetes prediction and, together, impro...

journal_title：Diabetes care

authors： Walford GA,Porneala BC,Dauriz M,Vassy JL,Cheng S,Rhee EP,Wang TJ,Meigs JB,Gerszten RE,Florez JC

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Limited information is available about glycemic outcomes with a closed-loop control (CLC) system compared with a predictive low-glucose suspend (PLGS) system. RESEARCH DESIGN AND METHODS:After 6 months of use of a CLC system in a randomized trial, 109 participants with type 1 diabetes (age range, 14-72 years...

journal_title：Diabetes care

authors： Brown SA,Beck RW,Raghinaru D,Buckingham BA,Laffel LM,Wadwa RP,Kudva YC,Levy CJ,Pinsker JE,Dassau E,Doyle FJ 3rd,Ambler-Osborn L,Anderson SM,Church MM,Ekhlaspour L,Forlenza GP,Levister C,Simha V,Breton MD,Kollman C,

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:To determine the effect of diabetes on long-term survival after acute myocardial infarction and to compare its effect with that of a previous myocardial infarction. RESEARCH DESIGN AND METHODS:In a prospective cohort study, we followed 1,935 patients hospitalized with a confirmed acute myocardial infarction ...

journal_title：Diabetes care

authors： Mukamal KJ,Nesto RW,Cohen MC,Muller JE,Maclure M,Sherwood JB,Mittleman MA

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To examine the relationship of retinal vascular caliber with diabetes, glycemia, and diabetic retinopathy. RESEARCH DESIGN AND METHODS:Population-based study using data from the Multi-Ethnic Study of Atherosclerosis (MESA), comprising 5,976 individuals (whites, blacks, Hispanics, and Chinese) residing in six...

journal_title：Diabetes care

authors： Nguyen TT,Wang JJ,Sharrett AR,Islam FM,Klein R,Klein BE,Cotch MF,Wong TY

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:We developed a scale to serve as a potential end point for 6-month glycemic progression (PS6M) toward type 1 diabetes (T1D) in autoantibody-positive relatives of individuals with T1D. RESEARCH DESIGN AND METHODS:The PS6M was developed from Diabetes Prevention Trial-Type 1 (DPT-1) data and tested in the Trial...

journal_title：Diabetes care

authors： Sosenko JM,Skyler JS,Beam CA,Boulware D,Mahon JL,Krischer JP,Greenbaum CJ,Rafkin LE,Matheson D,Herold KC,Palmer JP,Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups.

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Incidence of type 2 diabetes might be associated with preexisting hypertension. There is no information on whether incident diabetes is predicted by blood pressure control. We evaluated the hazard of diabetes in relation to blood pressure control in treated hypertensive patients. RESEARCH DESIGN AND METHODS:...

journal_title：Diabetes care

authors： Izzo R,de Simone G,Chinali M,Iaccarino G,Trimarco V,Rozza F,Giudice R,Trimarco B,De Luca N

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:Little is known about medial arterial calcification (MAC) other than its association with age, sex, diabetes, and diabetes complications. Familial aggregation of this disorder was studied to determine the importance of potential genetic factors and to assess whether such familial aggregation was independent o...

journal_title：Diabetes care

authors： Narayan KM,Pettitt DJ,Hanson RL,Bennett PH,Fernandes RJ,De Courten M,Rose FA,Knowler WC

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes is associated with a markedly increased risk of stroke, but only a few studies on the incidence of stroke in type 1 diabetes exist. Therefore, we assessed the incidence of stroke in patients with type 1 diabetes and studied the impact of diabetic nephropathy (DN) and severe diabetic retinopath...

journal_title：Diabetes care

authors： Hägg S,Thorn LM,Putaala J,Liebkind R,Harjutsalo V,Forsblom CM,Gordin D,Tatlisumak T,Groop PH,FinnDiane Study Group.

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The objective of this analysis was to evaluate the impact of several classes of oral antihyperglycemic therapy relative to sulfonylurea monotherapy on all-cause mortality among a cohort of patients with diabetes from the Veterans Health Administration (VHA). RESEARCH DESIGN AND METHODS:A retrospective cohort...

journal_title：Diabetes care

authors： Kahler KH,Rajan M,Rhoads GG,Safford MM,Demissie K,Lu SE,Pogach LM

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Studies in animal models suggest that ovarian hormone deficiency is associated with the development of insulin resistance. In women, ovarian hormone levels are dramatically reduced after the menopause transition. However, the effect of the menopause transition on insulin sensitivity is unclear. Thus, we exami...

journal_title：Diabetes care

authors： Toth MJ,Sites CK,Eltabbakh GH,Poehlman ET

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:High birth weight is a risk factor for neonatal complications. It is not known if the risk differs with body proportionality. The primary aim of this study was to determine the risk of adverse pregnancy outcome in relation to body proportionality in large-for-gestational-age (LGA) infants stratified by matern...

journal_title：Diabetes care

authors： Persson M,Fadl H,Hanson U,Pasupathy D

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate the rate of progression of nonalbuminuric chronic kidney disease (CKD) to end-stage kidney disease (ESKD) or death or major cardiovascular events (MACE) compared with albuminuric and nonalbuminuric phenotypes. RESEARCH DESIGN AND METHODS:We included 10,185 participants with type 2 dia...

journal_title：Diabetes care

authors： Buyadaa O,Magliano DJ,Salim A,Koye DN,Shaw JE

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Newer medications offer more options for glycemic control in type 2 diabetes. However, they come at considerable costs. We undertook a health economic analysis to better understand the value of adding two newer medications (exenatide and sitagliptin) as second-line therapy to glycemic control strategies for p...

journal_title：Diabetes care

authors： Sinha A,Rajan M,Hoerger T,Pogach L

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To estimate the cost-effectiveness of surgically induced weight loss relative to conventional therapy for the management of recently diagnosed type 2 diabetes in class I/II obese patients. RESEARCH DESIGN AND METHODS:This study builds on a within-trial cost-efficacy analysis. The analysis compares the lifeti...

journal_title：Diabetes care

authors： Keating CL,Dixon JB,Moodie ML,Peeters A,Bulfone L,Maglianno DJ,O'Brien PE

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To examine central nervous system involvement as a possible complication of diabetes by performing a comprehensive neuropsychological evaluation of relatively young (age < 55 years) NIDDM patients and a group of control subjects. RESEARCH DESIGN AND METHODS:A cross-sectional comparative study of 28 patients,...

journal_title：Diabetes care

authors： Dey J,Misra A,Desai NG,Mahapatra AK,Padma MV

更新日期：1997-01-01 00:00:00