Ketoacidosis at diabetes onset is still frequent in children and adolescents: a multicenter analysis of 14,664 patients from 106 institutions.

abstract：OBJECTIVE:In this prospective, randomized, open trial, we compared the efficacy and safety of aspart insulin given subcutaneously at different time intervals to a standard low-dose intravenous (IV) infusion protocol of regular insulin in patients with uncomplicated diabetic ketoacidosis (DKA). RESEARCH DESIGN AND METH...

journal_title：Diabetes care

authors： Umpierrez GE,Cuervo R,Karabell A,Latif K,Freire AX,Kitabchi AE

更新日期：2004-08-01 00:00:00

abstract：:Sixty-two subjects having either insulin-dependent or non-insulin-dependent diabetes completed a randomized, double-blind study comparing effects of aspartame or a placebo on blood glucose control. Twenty-nine subjects consumed 2.7 g aspartame per day for 18 wk, given as aspartame-containing capsules with meals, while...

journal_title：Diabetes care

authors： Nehrling JK,Kobe P,McLane MP,Olson RE,Kamath S,Horwitz DL

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:We previously demonstrated a direct correlation between serum insulin levels and gonadal androgens (testosterone and androstenedione) in a group of obese hyperandrogenic predominantly black women. Subsequent work by others in predominantly white women showed conflicting results. To examine these potentially i...

journal_title：Diabetes care

authors： Kitabchi AE,Imseis RE,Bush AJ,Williams-Cleaves B,Pourmotabbed G

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:Psychophysical methods in patients with diabetes mellitus reveal deficits of central or foveal vision. Our aim was to evaluate the contrast-sensitivity thresholds in 24 insulin-dependent (type I) diabetic patients with a short disease duration and without retinopathy, taking into account metabolic control. R...

journal_title：Diabetes care

authors： Di Leo MA,Caputo S,Falsini B,Porciatti V,Minnella A,Greco AV,Ghirlanda G

更新日期：1992-05-01 00:00:00

abstract：:We measured plasma lipid and lipoprotein levels at baseline and at 6-mo intervals in 47 normolipidemic patients with classic insulin-dependent diabetes mellitus treated either with a conventional (n = 21) or intensive (n = 26) diabetes-treatment program. Patients were followed for a mean of 3 yr (range 1-4 yr). Intens...

journal_title：Diabetes care

authors： Rosenstock J,Strowig S,Cercone S,Raskin P

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVE:To describe the association between Bacille Calmette-Guérin (BCG) vaccination and IDDM development in two different case-control series (A and B) in Montreal. RESEARCH DESIGN AND METHODS:Case-control series A comprised 93 IDDM cases and 2,903 control subjects who participated in a community-based tuberculin ...

journal_title：Diabetes care

authors： Parent ME,Siemiatycki J,Menzies R,Fritschi L,Colle E

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the effects of a combination weight loss program using intermittent low-calorie diets, energy-controlled meal replacement products, and sibutramine on weight loss, diabetes control, and cardiovascular risk factors in overweight or obese subjects with type 2 diabetes. ...

journal_title：Diabetes care

authors： Redmon JB,Raatz SK,Reck KP,Swanson JE,Kwong CA,Fan Q,Thomas W,Bantle JP

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the short-term impact of a 7-h type 2 diabetes continuing medical education (CME) program. Outcomes included a measure of health care providers' diabetes knowledge and the Diabetes Attitude Scale (DAS), a validated measure of attitudes toward diabetes. RESEARCH DES...

journal_title：Diabetes care

authors： Sharp LK,Lipsky MS

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Several methods have been proposed to evaluate insulin sensitivity from the data obtained from the oral glucose tolerance test (OGTT). However, the validity of these indices has not been rigorously evaluated by comparing them with the direct measurement of insulin sensitivity obtained with the euglycemic insu...

journal_title：Diabetes care

authors： Matsuda M,DeFronzo RA

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:To estimate real-world off-label use of sodium-glucose cotransporter 2 (SGLT2) inhibitors in patients with type 1 diabetes, estimate rates of diabetic ketoacidosis (DKA), and compare them with DKA rates observed in sotagliflozin clinical trials. RESEARCH DESIGN AND METHODS:We identified initiators of SGLT2 i...

journal_title：Diabetes care

authors： Hampp C,Swain RS,Horgan C,Dee E,Qiang Y,Dutcher SK,Petrone A,Chen Tilney R,Maro JC,Panozzo CA

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Changes in liver fatty acid metabolism are important in understanding the mechanisms of diabetes remission and metabolic changes after bariatric surgery. RESEARCH DESIGN AND METHODS:Liver fatty acid uptake (LFU), blood flow, and fat content (LFC) were measured in 25 obese subjects before bariatric surgery an...

journal_title：Diabetes care

authors： Immonen H,Hannukainen JC,Kudomi N,Pihlajamäki J,Saunavaara V,Laine J,Salminen P,Lehtimäki T,Pham T,Iozzo P,Nuutila P

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Impaired awareness of hypoglycemia (IAH) and recurrent severe hypoglycemia (RSH) remain problematic for people with type 1 diabetes (T1D), despite major therapeutic advances. We explored beliefs around hypo- and hyperglycemia in adults with T1D with, and without, IAH and RSH. RESEARCH DESIGN AND METHODS:A cr...

journal_title：Diabetes care

authors： Cook AJ,DuBose SN,Foster N,Smith EL,Wu M,Margiotta G,Rickels MR,Speight J,de Zoysa N,Amiel SA

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Because quantifying glycans with complex structures is technically challenging, little is known about the association of glycosylation profiles with the renal prognosis in diabetic kidney disease (DKD). RESEARCH DESIGN AND METHODS:In 675 patients with type 2 diabetes, we assessed the baseline urinary glycan ...

journal_title：Diabetes care

authors： Mise K,Imamura M,Yamaguchi S,Teshigawara S,Tone A,Uchida HA,Eguchi J,Nakatsuka A,Ogawa D,Yoshida M,Yamada M,Shikata K,Wada J

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the hospital care rendered to hyperglycemic individuals who did not have a diagnosis of diabetes before admission. RESEARCH DESIGN AND METHODS:A total of 1,034 consecutively hospitalized adult patients at a 750-bed inner-city teaching hospital were evaluated. Patients with one or more plasma gluc...

journal_title：Diabetes care

authors： Levetan CS,Passaro M,Jablonski K,Kass M,Ratner RE

更新日期：1998-02-01 00:00:00

abstract：:OBJECTIVE We previously reported that 2 years of costimulation modulation with abatacept slowed decline of β-cell function in recent-onset type 1 diabetes (T1D). Subsequently, abatacept was discontinued and subjects were followed to determine whether there was persistence of effect. RESEARCH DESIGN AND METHODS Of 112 ...

journal_title：Diabetes care

authors： Orban T,Bundy B,Becker DJ,Dimeglio LA,Gitelman SE,Goland R,Gottlieb PA,Greenbaum CJ,Marks JB,Monzavi R,Moran A,Peakman M,Raskin P,Russell WE,Schatz D,Wherrett DK,Wilson DM,Krischer JP,Skyler JS,Type 1 Diabetes Trial

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Congenital generalized lipodystrophy (CGL) is an autosomal recessive genetic disorder characterized by almost complete absence of adipose tissue, muscular appearance, and severe insulin resistance since birth. We investigated whether insulin resistance in CGL patients is associated with abnormal muscle morpho...

journal_title：Diabetes care

authors： Garg A,Stray-Gundersen J,Parsons D,Bertocci LA

更新日期：2000-10-01 00:00:00

abstract：:We describe affinity sensors for monitoring various metabolites in blood plasma by optical means. The principle of detection is similar to that used in radioimmunoassays and is based on the competitive binding of a particular metabolite and a fluorescein-labeled analogue with receptor sites specific for the metabolite...

journal_title：Diabetes care

authors： Schultz JS,Mansouri S,Goldstein IJ

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes is associated with a markedly increased risk of stroke, but only a few studies on the incidence of stroke in type 1 diabetes exist. Therefore, we assessed the incidence of stroke in patients with type 1 diabetes and studied the impact of diabetic nephropathy (DN) and severe diabetic retinopath...

journal_title：Diabetes care

authors： Hägg S,Thorn LM,Putaala J,Liebkind R,Harjutsalo V,Forsblom CM,Gordin D,Tatlisumak T,Groop PH,FinnDiane Study Group.

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:We assessed the extent to which both standard and alternative indexes from 2-h oral glucose tolerance testing predict type 1 diabetes and whether oral glucose tolerance tests (OGTTs) predict type 1 diabetes in individuals with normal glucose tolerance. RESEARCH DESIGN AND METHODS:The prediction of type 1 dia...

journal_title：Diabetes care

authors： Sosenko JM,Palmer JP,Greenbaum CJ,Mahon J,Cowie C,Krischer JP,Chase HP,White NH,Buckingham B,Herold KC,Cuthbertson D,Skyler JS,Diabetes Prevention Trial-Type 1 Study Group.

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To evaluate statin use in the U.S. before and after the 2015 American Diabetes Association position statement, which expanded statin therapy recommendations to include all adults 40-75 years old with diabetes. RESEARCH DESIGN AND METHODS:The National Health and Nutrition Examination Survey (NHANES) was used ...

journal_title：Diabetes care

authors： Leino AD,Dorsch MP,Lester CA

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To assess the association of 1-h plasma glucose (1hPG) and inflammation with normal glucose tolerance (NGT) and pre-diabetes. RESEARCH DESIGN AND METHODS:A cohort of 1,062 subjects was enrolled. After oral glucose load (oral glucose tolerance test), we compared subjects with NGT and pre-diabetes above and be...

journal_title：Diabetes care

authors： Bardini G,Dicembrini I,Cresci B,Rotella CM

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Strict glycemic control in people with insulin-dependent diabetes mellitus (IDDM) reduces the risk of microvascular complications, but improvements in control are also associated with weight gain. Fears about the mortality risks of obesity may limit the acceptability of tight control. Therefore, we examined m...

journal_title：Diabetes care

authors： Chaturvedi N,Stevens LK,Fuller JH

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:To examine the independent and combined association of isometric muscle strength of the abdomen and back and cardiorespiratory fitness (CRF) in youth with indices of glucose metabolism in young adulthood among boys and girls from the European Youth Heart Study. RESEARCH DESIGN AND METHODS:We used data from a...

journal_title：Diabetes care

authors： Grøntved A,Ried-Larsen M,Ekelund U,Froberg K,Brage S,Andersen LB

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Given the transient nature of exercise-induced improvements in insulin sensitivity, it has been speculated that daily exercise is preferred to maximize the benefits of exercise for glycemic control. The current study investigates the impact of daily exercise versus exercise performed every other day on glycem...

journal_title：Diabetes care

authors： van Dijk JW,Tummers K,Stehouwer CD,Hartgens F,van Loon LJ

更新日期：2012-05-01 00:00:00

abstract：:Type 1 diabetes (T1D) and celiac disease (CeD) cluster in families and can occur in the same individual. Genetic loci have been associated with susceptibility to both diseases. Our aim was to explore the genetic differences between individuals developing both these diseases (double autoimmunity) versus those with only...

journal_title：Diabetes care

authors： Gutierrez-Achury J,Romanos J,Bakker SF,Kumar V,de Haas EC,Trynka G,Ricaño-Ponce I,Steck A,Type 1 Diabetes Genetics Consortium.,Chen WM,Onengut-Gumuscu S,Simsek S,Diabeter.,Rewers M,Mulder CJ,Liu E,Rich SS,Wijmenga C

更新日期：2015-10-01 00:00:00

abstract：:Nocturnal hypoglycemia in insulin-treated diabetic persons is often difficult to recognize clinically. It has been suggested that a useful biochemical test to demonstrate this would be the increased excretion of cortisol in the urine during the overnight period. However, of six diabetic persons who had nocturnal hypog...

journal_title：Diabetes care

authors： Scott RS,Scandrett MS

更新日期：1981-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the presence and correlates of clinically relevant cognitive impairment in middle-aged adults with childhood-onset type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS:During 2010-2013, 97 adults diagnosed with T1D and aged <18 years (age and duration 49 ± 7 and 41 ± 6 ...

journal_title：Diabetes care

authors： Nunley KA,Rosano C,Ryan CM,Jennings JR,Aizenstein HJ,Zgibor JC,Costacou T,Boudreau RM,Miller R,Orchard TJ,Saxton JA

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Screening involves the presumptive identification of asymptomatic individuals at increased risk for unrecognized disease. We examined changes in screening practices for prediabetes and diabetes since January 2010, when HbA1c was first recommended as an option for screening and diagnosis. RESEARCH DESIGN AND ...

journal_title：Diabetes care

authors： Evron JM,Herman WH,McEwen LN

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Prevalence and prognostic impact of cardiovascular disease differ between patients with or without diabetes. We aimed to explore differences in the prevalence and prognosis of myocardial ischemia by automated quantification of total perfusion deficit (TPD) among patients with and without diabetes. RESEARCH D...

journal_title：Diabetes care

authors： Han D,Rozanski A,Gransar H,Sharir T,Einstein AJ,Fish MB,Ruddy TD,Kaufmann PA,Sinusas AJ,Miller EJ,Bateman TM,Dorbala S,Di Carli M,Liang JX,Hu LH,Germano G,Dey D,Berman DS,Slomka PJ

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To examine ankle-brachial index (ABI) abnormalities in patients with type 2 diabetes and coronary artery disease (CAD). RESEARCH DESIGN AND METHODS:An ABI was obtained in 2,240 patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial. ABIs were classified as: normal, 0.91...

journal_title：Diabetes care

authors： Singh PP,Abbott JD,Lombardero MS,Sutton-Tyrrell K,Woodhead G,Venkitachalam L,Tsapatsaris NP,Piemonte TC,Lago RM,Rutter MK,Nesto RW,Bypass Angioplasty Revascularization Investigation 2 Diabetes Study Group.

更新日期：2011-02-01 00:00:00