Long-term trends in cardiorespiratory fitness and the incidence of type 2 diabetes.

Abstract:

OBJECTIVE:Whereas single assessments of cardiorespiratory fitness have been shown to predict lower incidence of type 2 diabetes, there are no data on long-term trends in fitness and risk. We investigated the relationship between long-term trends in fitness and the incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS:A cohort of 4,187 Japanese men free of diabetes completed annual health checkups and fitness tests for estimated maximal oxygen uptake at least four times over 7 years (1979-1985). We modeled the trend in fitness over 7 years for each man using simple linear regression. Men were then divided into quartiles based on the regression coefficient (slope) from the model. During the follow-up period (1985-1999), 274 men developed diabetes. Hazard ratios (HRs) and 95% CIs for the incidence of diabetes were obtained using the Cox proportional hazards model. RESULTS:Men in the lowest quartile of the distribution decreased in fitness over the 7 years (median slope -1.25 ml/kg/min), whereas men in the highest quartile increased in fitness (median slope 1.33 ml/kg/min). With adjustment for age, initial fitness level, BMI, systolic blood pressure, cigarette smoking, alcohol intake, and a family history of diabetes and use of the lowest quartile, the HRs (95% CI) for the second through fourth quartiles were 0.64 (0.46-0.89), 0.40 (0.27-0.58), and 0.33 (0.21-0.50), respectively (P(trend) < 0.001). CONCLUSIONS:These results indicate that the long-term trend in fitness is a strong predictor of the incidence of type 2 diabetes in Japanese men.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Sawada SS,Lee IM,Naito H,Noguchi J,Tsukamoto K,Muto T,Higaki Y,Tanaka H,Blair SN

doi

10.2337/dc09-1654

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

1353-7

issue

6

eissn

0149-5992

issn

1935-5548

pii

dc09-1654

journal_volume

33

pub_type

杂志文章
  • Vital signs, QT prolongation, and newly diagnosed cardiovascular disease during severe hypoglycemia in type 1 and type 2 diabetic patients.

    abstract::OBJECTIVE To assess vital signs, QT intervals, and newly diagnosed cardiovascular disease during severe hypoglycemia in diabetic patients. RESEARCH DESIGN AND METHODS From January 2006 to March 2012, we conducted a retrospective cohort study to assess type 1 and type 2 diabetic patients with severe hypoglycemia at a n...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc13-0701

    authors: Tsujimoto T,Yamamoto-Honda R,Kajio H,Kishimoto M,Noto H,Hachiya R,Kimura A,Kakei M,Noda M

    更新日期:2014-01-01 00:00:00

  • Measurement of glucose concentration in the presence of coreactants with a platinum electrode.

    abstract::An implantable glucose sensor is being developed that is based on the use of a high-area platinum electrode. The sensor is operated in a controlled potential mode, in which the potential of the platinum working electrode versus an unpolarized reference electrode is periodically varied according to a preselected voltag...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.5.3.229

    authors: Lerner H,Soeldner JS,Colton CK,Giner J

    更新日期:1982-05-01 00:00:00

  • Frequency of severe hypoglycemia in patients with type I diabetes with impaired awareness of hypoglycemia.

    abstract:OBJECTIVE:To determine the frequency of hypoglycemia in patients with type I diabetes and impaired awareness of hypoglycemia by prospective assessment. RESEARCH DESIGN AND METHODS:A prospective study was undertaken for 12 months in 60 patients with type I diabetes: 29 had impaired awareness of hypoglycemia and 31 reta...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章

    doi:10.2337/diacare.17.7.697

    authors: Gold AE,MacLeod KM,Frier BM

    更新日期:1994-07-01 00:00:00

  • Increased foot pressures after great toe amputation in diabetes.

    abstract:OBJECTIVE:To compare peak pressures on the sole of the foot in non-insulin-dependent diabetic patients with isolated, unilateral amputations of the great toe and first metatarsal with the patients' contralateral, intact foot. RESEARCH DESIGN AND METHODS:Eleven patients with a unilateral great toe and partial first met...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.18.11.1460

    authors: Lavery LA,Lavery DC,Quebedeax-Farnham TL

    更新日期:1995-11-01 00:00:00

  • The community ecology of diabetes patient classification and practice characteristics.

    abstract::We examined the clinical and epidemiologic characteristics of diabetic subjects ascertained from five different sources (hospital, private practice, specialist practice, nursing home, and prevalence survey) in a medium-sized upstate New York community. Patients were categorized using the National Diabetes Data Group c...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.8.1.s87

    authors: Rothenberg RB,Olsen CL,Schnure JJ,Gerber TM,Cohen J,Curtis GB,Jesserer J,Roach J,Wirth C

    更新日期:1985-09-01 00:00:00

  • Effect of diabetes on renal medullary oxygenation during water diuresis.

    abstract:OBJECTIVES:To study the effect of water diuresis on renal medullary and cortical oxygenation in patients with diabetes using blood oxygenation level--dependent magnetic resonance imaging (BOLD MRI). RESEARCH DESIGN AND METHODS:Nine mild diabetic subjects (48 +/- 2.7 years of age, six women) and nine nondiabetic subjec...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.25.3.575

    authors: Epstein FH,Veves A,Prasad PV

    更新日期:2002-03-01 00:00:00

  • Affinity of IgG-insulin antibodies to human (recombinant DNA) insulin and porcine insulin in insulin-treated diabetic individuals with and without insulin resistance.

    abstract::The affinity of human (recombinant DNA) insulin and porcine insulin to preformed IgG-insulin antibodies of insulin-treated diabetic individuals was studied in 29 insulin-treated diabetic patients. The binding of 125I-human insulin and 125I-porcine insulin with antibodies was similar in the group of patients without in...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.5.2.s114

    authors: Schernthaner G

    更新日期:1982-11-01 00:00:00

  • Risk factors for plantar foot ulcer recurrence in neuropathic diabetic patients.

    abstract:OBJECTIVE:Recurrence of plantar foot ulcers is a common and major problem in diabetes but not well understood. Foot biomechanics and patient behavior may be important. The aim was to identify risk factors for ulcer recurrence and to establish targets for ulcer prevention. RESEARCH DESIGN AND METHODS:As part of a footw...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc13-2470

    authors: Waaijman R,de Haart M,Arts ML,Wever D,Verlouw AJ,Nollet F,Bus SA

    更新日期:2014-06-01 00:00:00

  • Variations of ambulatory blood pressure with position in patients with type 1 diabetes: influence of disease duration and microangiopathy in a pilot study.

    abstract:OBJECTIVE:To study the influence of position changes on 24-h ambulatory blood pressure (ABP) in normotensive or mildly hypertensive normoalbuminuric patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:A cross-sectional evaluation of patients was staged according to the duration of diabetes (DD) and the presence...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.24.9.1624

    authors: Benhamou PY,Mouret S,Quesada JL,Boizel R,Baguet JP,Halimi S,Mallion JM

    更新日期:2001-09-01 00:00:00

  • Incidence of type 2 diabetes using proposed HbA1c diagnostic criteria in the european prospective investigation of cancer-norfolk cohort: implications for preventive strategies.

    abstract:OBJECTIVE:To evaluate the incidence and relative risk of type 2 diabetes defined by the newly proposed HbA(1c) diagnostic criteria in groups categorized by different baseline HbA(1c) levels. RESEARCH DESIGN AND METHODS:Using data from the European Prospective Investigation of Cancer (EPIC)-Norfolk cohort with repeat H...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-2326

    authors: Chamnan P,Simmons RK,Forouhi NG,Luben RN,Khaw KT,Wareham NJ,Griffin SJ

    更新日期:2011-04-01 00:00:00

  • Nonfasting plasma glucose is a better marker of diabetic control than fasting plasma glucose in type 2 diabetes.

    abstract:OBJECTIVE:To evaluate the relative value of plasma glucose (PG) at different time points in assessing glucose control of type 2 diabetic patients. RESEARCH DESIGN AND METHODS:Glycemic profiles, i.e., PG at prebreakfast (8:00 A.M.), prelunch (11:00 A.M.), postlunch (2:00 P.M.), and extended postlunch (5:00 P.M.) times ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.12.1822

    authors: Avignon A,Radauceanu A,Monnier L

    更新日期:1997-12-01 00:00:00

  • The association between different A1C-based measures of glycemia and risk of cardiovascular disease hospitalization.

    abstract::OBJECTIVE We tested whether average monthly glycemic burden (AMGB), a marker of hyperglycemia that is a function of the extent and duration that A1C exceeded 7%, indicated greater risk of cardiovascular disease (CVD) than traditional A1C measures. RESEARCH DESIGN AND METHODS Using a case-control design, we studied 2,4...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc13-1300

    authors: Nichols GA,Rosales AG,Perrin NA,Fortmann SP

    更新日期:2014-01-01 00:00:00

  • Validation of a counseling strategy to promote the adoption and the maintenance of physical activity by type 2 diabetic subjects.

    abstract:OBJECTIVE:There is enough evidence that physical activity is an effective therapeutic tool in the management of type 2 diabetes. The present study was designed to validate a counseling strategy that could be used by physicians in their daily outpatient practice to promote the adoption and maintenance of physical activi...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.26.2.404

    authors: Di Loreto C,Fanelli C,Lucidi P,Murdolo G,De Cicco A,Parlanti N,Santeusanio F,Brunetti P,De Feo P

    更新日期:2003-02-01 00:00:00

  • Effectiveness of early intensive therapy on β-cell preservation in type 1 diabetes.

    abstract:OBJECTIVE:To assess effectiveness of inpatient hybrid closed-loop control (HCLC) followed by outpatient sensor-augmented pump (SAP) therapy initiated within 7 days of diagnosis of type 1 diabetes on the preservation of β-cell function at 1 year. RESEARCH DESIGN AND METHODS:Sixty-eight individuals (mean age 13.3 ± 5.7 ...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc13-1074

    authors: Buckingham B,Beck RW,Ruedy KJ,Cheng P,Kollman C,Weinzimer SA,DiMeglio LA,Bremer AA,Slover R,Tamborlane WV,Diabetes Research in Children Network (DirecNet) Study Group.,Type 1 Diabetes TrialNet Study Group.

    更新日期:2013-12-01 00:00:00

  • Sexual dysfunction in Jordanian diabetic women.

    abstract:OBJECTIVE:To estimate the prevalence of female sexual dysfunction (FSD) in diabetic and nondiabetic Jordanian women. RESEARCH DESIGN AND METHODS:Data were collected from 1,137 married women using the Arabic translation of the Female Sexual Function Index questionnaire. RESULTS:Prevalence of sexual dysfunction in diab...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-0081

    authors: Abu Ali RM,Al Hajeri RM,Khader YS,Shegem NS,Ajlouni KM

    更新日期:2008-08-01 00:00:00

  • Obstructive sleep apnea and diabetic nephropathy: a cohort study.

    abstract:OBJECTIVE:Diabetic nephropathy (DN) is a leading cause of end-stage renal disease (ESRD). Obstructive sleep apnea (OSA) is common in type 2 diabetes and increases oxidative stress. Hence, OSA could promote the development and progression of DN. RESEARCH DESIGN AND METHODS:This was a cohort study in adults with type 2 ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc13-0450

    authors: Tahrani AA,Ali A,Raymond NT,Begum S,Dubb K,Altaf QA,Piya MK,Barnett AH,Stevens MJ

    更新日期:2013-11-01 00:00:00

  • Anti-inflammatory and anticoagulant effects of pravastatin in patients with type 2 diabetes.

    abstract:OBJECTIVE:Type 2 diabetes is associated with increased plasma concentrations of coagulation and inflammation markers. Different studies have shown that treatment with hydroxymethylglutaryl-CoA reductase inhibitors (statins) is associated with antithrombotic and anti-inflammatory effects in addition to a cholesterol-low...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.2337/diacare.27.2.468

    authors: Sommeijer DW,MacGillavry MR,Meijers JC,Van Zanten AP,Reitsma PH,Ten Cate H

    更新日期:2004-02-01 00:00:00

  • Haptoglobin genotype is predictive of major adverse cardiac events in the 1-year period after percutaneous transluminal coronary angioplasty in individuals with diabetes.

    abstract:OBJECTIVE:The goal of this study was to determine whether the haptoglobin (Hp) genotype was predictive of restenosis and major adverse cardiac events (MACEs) after percutaneous transluminal coronary angioplasty (PTCA) in individuals with diabetes. RESEARCH DESIGN AND METHODS:A consecutive series of 935 diabetic patien...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.26.9.2628

    authors: Roguin A,Koch W,Kastrati A,Aronson D,Schomig A,Levy AP

    更新日期:2003-09-01 00:00:00

  • Factors associated with glycemic control. A cross-sectional nationwide study in 2,579 French children with type 1 diabetes. The French Pediatric Diabetes Group.

    abstract:OBJECTIVE:To determine on a large scale the multiple medical and nonmedical factors that influence glycemic control in the general population of children with diabetes, we performed a nationwide French cross-sectional study. RESEARCH DESIGN AND METHODS:We enrolled 2,579 patients aged 1-19 years with type 1 diabetes of...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/diacare.21.7.1146

    authors: Rosilio M,Cotton JB,Wieliczko MC,Gendrault B,Carel JC,Couvaras O,Ser N,Gillet P,Soskin S,Garandeau P,Stuckens C,Le Luyer B,Jos J,Bony-Trifunovic H,Bertrand AM,Leturcq F,Lafuma A,French Pediatric Diabetes Group,Bougnèr

    更新日期:1998-07-01 00:00:00

  • Effect of training status on regional disposal of circulating free fatty acids in the liver and skeletal muscle during physiological hyperinsulinemia.

    abstract:OBJECTIVE:Fat metabolism is increasingly implicated in the pathogenesis of type 2 diabetes. Endurance training has been shown to prevent hepatic steatosis and to alter skeletal muscle fat metabolism, and regional free fatty acid (FFA) uptake adaptations were suggested as a mechanism. Thus, we tested whether endurance t...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.27.9.2172

    authors: Iozzo P,Takala T,Oikonen V,Bergman J,Grönroos T,Ferrannini E,Nuutila P,Knuuti J

    更新日期:2004-09-01 00:00:00

  • Utility of casual postprandial glucose levels in type 2 diabetes management.

    abstract:OBJECTIVE:Because readily available glycemic indicators are needed to guide clinical decision-making for intensification of diabetes therapy, our goals were to define the relationship between casual postprandial plasma glucose (cPPG) levels and HbA(1c) in patients with type 2 diabetes and to determine the predictive ch...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.27.2.335

    authors: El-Kebbi IM,Ziemer DC,Cook CB,Gallina DL,Barnes CS,Phillips LS

    更新日期:2004-02-01 00:00:00

  • Controlled trial of a multifaceted intervention for improving quality of care for rural patients with type 2 diabetes.

    abstract:OBJECTIVE:Despite good evidence and clinical practice guidelines, studies document that treatment of type 2 diabetes is less than optimal. Lack of resources or limited access may put patients in rural communities at particular risk for suboptimal care. RESEARCH DESIGN AND METHODS:We conducted a prospective, before/aft...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.26.11.3061

    authors: Majumdar SR,Guirguis LM,Toth EL,Lewanczuk RZ,Lee TK,Johnson JA

    更新日期:2003-11-01 00:00:00

  • Skeletal muscle morphology and exercise response in congenital generalized lipodystrophy.

    abstract:OBJECTIVE:Congenital generalized lipodystrophy (CGL) is an autosomal recessive genetic disorder characterized by almost complete absence of adipose tissue, muscular appearance, and severe insulin resistance since birth. We investigated whether insulin resistance in CGL patients is associated with abnormal muscle morpho...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.23.10.1545

    authors: Garg A,Stray-Gundersen J,Parsons D,Bertocci LA

    更新日期:2000-10-01 00:00:00

  • Is pancreatic diabetes (type 3c diabetes) underdiagnosed and misdiagnosed?

    abstract::Exocrine pancreatic insufficiency is frequently associated with diabetes, with high prevalence in both insulin-dependent or insulin-independent patients. Exocrine pancreatic failure has often been perceived as a complication of diabetes. In contrast, recent clinical observations lead to the notion that nonendocrine pa...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:10.2337/dc08-s244

    authors: Hardt PD,Brendel MD,Kloer HU,Bretzel RG

    更新日期:2008-02-01 00:00:00

  • Impaired endothelial function in preadolescent children with type 1 diabetes.

    abstract:OBJECTIVE:We evaluated the prevalence of endothelial dysfunction as measured by flow-mediated dilatation (FMD) of the brachial artery and carotid intima-media thickness (c-IMT) in relationship to vascular inflammatory biomarkers in preadolescent children with type 1 diabetes. RESEARCH DESIGN AND METHODS:We studied 21 ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-2134

    authors: Babar GS,Zidan H,Widlansky ME,Das E,Hoffmann RG,Daoud M,Alemzadeh R

    更新日期:2011-03-01 00:00:00

  • Short-term exenatide treatment leads to significant weight loss in a subset of obese women without diabetes.

    abstract:OBJECTIVE:To investigate the effect of treatment with the glucagon-like peptide 1 receptor agonist exenatide on weight loss and metabolic parameters in obese nondiabetic women. RESEARCH DESIGN AND METHODS:Forty-one obese women (aged 48 ± 11 years and BMI 33.1 ± 4.1 kg/m(2)) participated in a 35-week randomized, double...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc11-0931

    authors: Dushay J,Gao C,Gopalakrishnan GS,Crawley M,Mitten EK,Wilker E,Mullington J,Maratos-Flier E

    更新日期:2012-01-01 00:00:00

  • Global Disability Burdens of Diabetes-Related Lower-Extremity Complications in 1990 and 2016.

    abstract:OBJECTIVE:No study has reported global disability burden estimates for individual diabetes-related lower-extremity complications (DRLECs). The Global Burden of Disease (GBD) study presents a robust opportunity to address this gap. RESEARCH DESIGN AND METHODS:GBD 2016 data, including prevalence and years lived with dis...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-1614

    authors: Zhang Y,Lazzarini PA,McPhail SM,van Netten JJ,Armstrong DG,Pacella RE

    更新日期:2020-05-01 00:00:00

  • Dietary pectin and glycemic control in diabetes.

    abstract::Seventeen diabetic subjects requiring insulin and who exhibited glycemic stability over a 9-12-mo control period received 5 g of pectin with each meal and at bedtime for 3 mo. Hemoglobin A1c (HbA1c) and glycosylated serum protein were measured in each patient on multiple occasions to assess glycemic control. No clear-...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.7.2.143

    authors: Gardner DF,Schwartz L,Krista M,Merimee TJ

    更新日期:1984-03-01 00:00:00

  • Evaluation of patient's knowledge of diabetes self-care.

    abstract::A survey conducted at a Veterans Administration Hospital to evaluate patient capability for self-management found that over 35 per cent of the patients interviewed lacked any formal training. Seventeen patients had been placed on insulin without formal instruction. Almost one half the patients who claimed to have atte...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.1.5.275

    authors: Miller LV,Goldstein J,Nicolaisen G

    更新日期:1978-09-01 00:00:00

  • Life years lost and lifetime health care expenditures associated with diabetes in the U.S., National Health Interview Survey, 1997-2000.

    abstract:OBJECTIVE:This study analyzed the lifetime health care expenditures and life years lost associated with diabetes in the U.S. RESEARCH DESIGN AND METHODS:Data from the National Health Interview Survey (NHIS), the Medical Expenditure Panel Survey from 1997 to 2000, and the NHIS Linked Mortality Public-use Files with a m...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc14-1453

    authors: Leung MY,Pollack LM,Colditz GA,Chang SH

    更新日期:2015-03-01 00:00:00