Frequency of severe hypoglycemia in patients with type I diabetes with impaired awareness of hypoglycemia.

abstract：OBJECTIVE:Hypoglycemic symptoms have been reported by more than half of pancreas transplantation (PTX) recipients. To better understand the mechanism for the hypoglycemia documented in some of these patients, we studied the glucose and pancreatic hormone response to Sustacal in patients with and without hypoglycemia fo...

journal_title：Diabetes care

authors： Tran MP,Larsen JL,Duckworth WC,Ruby EI,Miller SA,Frisbie K,Taylor RJ,Stratta RJ

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To investigate the association of carotid atherosclerosis and serum lipoprotein(a) [Lp(a)] concentrations in subjects with NIDDM. RESEARCH DESIGN AND METHODS:We measured carotid intima-media thickness (IMT) and Lp(a) concentrations in 117 NIDDM subjects. Subjects were divided into tertiles according to IMT v...

journal_title：Diabetes care

authors： Yamamoto M,Egusa G,Yamakido M

更新日期：1997-05-01 00:00:00

abstract：:To assess the possible value of the use of high-purity pork insulin (HPPI) in the United States, the serum insulin (I), pancreatic polypeptide (PP), glucagon (G), and somatostatin (SRIF) antibody binding characteristics have been determined in 90 conventional insulin-treated diabetic subjects and related to their degr...

journal_title：Diabetes care

authors： Asplin CM,Hollander P,Pecoraro RE,Brodsky J,Palmer JP

更新日期：1981-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of flexible intensive insulin therapy (FIIT) and an automated bolus calculator (ABC) in a Danish type 1 diabetes population treated with multiple daily injections. Furthermore, to test the feasibility of teaching FIIT in a 3-h structured course. RESEARCH DESIGN AND METHODS:The Bolus...

journal_title：Diabetes care

authors： Schmidt S,Meldgaard M,Serifovski N,Storm C,Christensen TM,Gade-Rasmussen B,Nørgaard K

更新日期：2012-05-01 00:00:00

abstract：:The complexity of the several pathogenic pathways that cause hypertension and vascular disease and the prolonged interval that appears to predate clinical morbidity have hindered inquiry into the association between GDM and vascular disorders. As a forme fruste of later type 2 diabetes, GDM-affected gravidas are ident...

journal_title：Diabetes care

authors： Carpenter MW

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Previous studies have suggested that diabetes increases the risk of Parkinson disease (PD); however, this has not been conclusively established. We analyzed the risk of PD based on baseline glucose tolerance status in a large-scale cohort representative of the general Korean population. RESEARCH DESIGN AND M...

journal_title：Diabetes care

authors： Rhee SY,Han KD,Kwon H,Park SE,Park YG,Kim YH,Yoo SJ,Rhee EJ,Lee WY

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:N-acetylglucosamine/galactosamine (GlycA) and sialic acid (GlycB) moieties of glycosylated serum proteins are nonspecific measures of inflammation, but conclusive data on their relationship with insulin resistance or insulin secretion are missing. Therefore, we aimed to examine the relation of GlycA, GlycB, a...

journal_title：Diabetes care

authors： Lorenzo C,Festa A,Hanley AJ,Rewers MJ,Escalante A,Haffner SM

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To determine the occurrence of elevated fetal hemoglobin (HbF) among the diabetic population and determine the clinical situation of importance. RESEARCH DESIGN AND METHODS:A cross-sectional study was conducted. HbA1c and HbF were measured with high-performance liquid chromatography in 1,104 consecutive diab...

journal_title：Diabetes care

authors： Koskinen LK,Lahtela JT,Koivula TA

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:To determine whether perceived risk and other health beliefs held by individuals at high risk for developing NIDDM predict weight loss and behavior change during a behavioral weight loss program to reduce the risk of NIDDM. RESEARCH DESIGN AND METHODS:Health beliefs and objective risk factors for diabetes we...

journal_title：Diabetes care

authors： Polley BA,Jakicic JM,Venditti EM,Barr S,Wing RR

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:We investigated whether islet autoantibody profile, HLA-DQ genotype, and age influenced a 20-year progression to diabetes from first autoantibody positivity (autoAb+) in first-degree relatives of patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Persistently islet autoAb+ siblings and offspring (n =...

journal_title：Diabetes care

authors： Gorus FK,Balti EV,Messaaoui A,Demeester S,Van Dalem A,Costa O,Dorchy H,Mathieu C,Van Gaal L,Keymeulen B,Pipeleers DG,Weets I,Belgian Diabetes Registry.

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Obesity is associated with alterations in corticolimbic-striatal brain regions involved in food motivation and reward. Stress and the presence of food cues may each motivate eating and engage corticolimibic-striatal neurocircuitry. It is unknown how these factors interact to influence brain responses and whet...

journal_title：Diabetes care

authors： Jastreboff AM,Sinha R,Lacadie C,Small DM,Sherwin RS,Potenza MN

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:Our objective was to compare the performance of oral glucose tolerance tests (OGTTs) and multivariate models incorporating commonly available clinical variables in their ability to predict future cardiovascular disease (CVD). RESEARCH DESIGN AND METHODS:We randomly selected 2,662 Mexican-Americans and 1,595 ...

journal_title：Diabetes care

authors： Stern MP,Fatehi P,Williams K,Haffner SM

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between self-reported diabetes and the risk of breast cancer (BC) and its interaction with moderate-intensity physical activity in pre- and postmenopausal Mexican women. RESEARCH DESIGN AND METHODS:A population-based case-control study was conducted using 1,000 incident case subje...

journal_title：Diabetes care

authors： Torres-Mejía G,Angeles-Llerenas A,Ortega-Olvera C,Lazcano-Ponce E,Ziv E,Pulido-Rodríguez J,García-Solis Mde J,Murillo-Zamora E,Vázquez-Lara J,Romieu I

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:The role of general practice and diabetes clinics in the management of diabetes is still a matter of debate. Methodological flaws in previous studies may have led to inaccurate conclusions when comparing the care provided in these different settings. We compared the care provided to type 2 diabetic patients a...

journal_title：Diabetes care

authors： De Berardis G,Pellegrini F,Franciosi M,Belfiglio M,Di Nardo B,Greenfield S,Kaplan SH,Rossi MC,Sacco M,Tognoni G,Valentini M,Nicolucci A,QuED Study.

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:It has proved difficult to separate the role of the diabetic state as distinct from its complications in causing the elevation in erythrocyte sodium-lithium (Na-Li) countertransport activity that has been observed in diabetes. The present study sought to isolate the impact of diabetes on the countertransporte...

journal_title：Diabetes care

authors： Hardman TC,Dubrey SW,Leslie RD,Lant AF

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the association between foot ulcers (DFU) and lower-extremity amputation (LEA) and chronic kidney disease (CKD) in patients with diabetes. RESARCH DESIGN AND METHODS: This was a retrospective cohort study of individuals enrolled between 2002 and 2006 who were aged >...

journal_title：Diabetes care

authors： Margolis DJ,Hofstad O,Feldman HI

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To determine the association between triglyceride levels and lower-extremity amputation (LEA) risk in a large diabetic cohort. RESEARCH DESIGN AND METHODS:This is a 10-year survey follow-up study (from 1995-2006) of 28,701 diabetic patients with a baseline triglyceride measure. All patients were fully insure...

journal_title：Diabetes care

authors： Callaghan BC,Feldman E,Liu J,Kerber K,Pop-Busui R,Moffet H,Karter AJ

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To compare albumin-to-creatinine ratio (ACR) and albumin concentration (ALB) for detection of microalbuminuria using precise data on CIs for sensitivity and specificity and to determine sex- and age-specific discriminator values for ACR. RESEARCH DESIGN AND METHODS:All consecutive patients investigated for t...

journal_title：Diabetes care

authors： Bakker AJ

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:To examine the impact of Hurricane Katrina on the health of individuals with diabetes. RESEARCH DESIGN AND METHODS:This was an observational study in 1,795 adults with an A1C measurement 6 months before and 6-16 months after Hurricane Katrina in three health care systems: private (Tulane University Hospital ...

journal_title：Diabetes care

authors： Fonseca VA,Smith H,Kuhadiya N,Leger SM,Yau CL,Reynolds K,Shi L,McDuffie RH,Thethi T,John-Kalarickal J

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Hypoxia plays a major pathogenic role in diabetic nephropathy (DN). We have investigated in this study the effect of hypoxia-inducible factor 1 α subunit (HIF1A) genetic polymorphisms on the development of DN. RESEARCH DESIGN AND METHODS:In 1,165 American type 1 diabetic patients with and without DN selected...

journal_title：Diabetes care

authors： Gu HF,Zheng X,Abu Seman N,Gu T,Botusan IR,Sunkari VG,Lokman EF,Brismar K,Catrina SB

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:The impact of major affective disorders on the effectiveness of diabetes prevention programs at promoting health behaviors has not been established. We investigated whether depression modifies the effectiveness of two pragmatic diabetes prevention programs at promoting increased physical activity. RESEARCH D...

journal_title：Diabetes care

authors： Yates T,Gray LJ,Henson J,Edwardson CL,Khunti K,Davies MJ

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Alterations of pancreatic β-cell cholesterol content may contribute to β-cell dysfunction. Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Whether genetic variation in ABCA1 and ABCG1 predicts risk of type 2 diabetes i...

journal_title：Diabetes care

authors： Schou J,Tybjærg-Hansen A,Møller HJ,Nordestgaard BG,Frikke-Schmidt R

更新日期：2012-12-01 00:00:00

abstract：:Nutrient intake plays a significant role in the health outcomes of all pregnant women. In a pregnancy complicated by gestational diabetes mellitus (GDM), excellent glucose control is as foundational as appropriate weight gain and adequate nutrient intake. The controversies in GDM management include the following: how ...

journal_title：Diabetes care

authors： Reader DM

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:This study describes changes in the distribution of cigarette smoking and in physicians' advice to quit smoking among the U.S. population with and without diabetes from the mid-1970s to 1990. RESEARCH DESIGN AND METHODS:Data on self-reported smoking status, physicians' advice to quit smoking, history of diab...

journal_title：Diabetes care

authors： Malarcher AM,Ford ES,Nelson DE,Chrismon JH,Mowery P,Merritt RK,Herman WH

更新日期：1995-05-01 00:00:00

abstract：:In this study, 18 type I (insulin-dependent) diabetic subjects aged 22-35 yr (mean age 29.3) and within 10 yr of diagnosis (mean 7.7) performed a battery of cognitive and psychomotor tasks under conditions of hypoglycemia (50 mg/dl), normoglycemia (100 mg/dl), and hyperglycemia (300 mg/dl). Blood glucose levels during...

journal_title：Diabetes care

authors： Hoffman RG,Speelman DJ,Hinnen DA,Conley KL,Guthrie RA,Knapp RK

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility that leptin levels may be predictive of the risk of ischemic heart disease (IHD) through the relationship of leptin to body fat. RESEARCH DESIGN AND METHODS:The Quebec Cardiovascular Study cohort consisted of 2,103 French-Canadian men without IHD in 1985 who were followed until...

journal_title：Diabetes care

authors： Couillard C,Lamarche B,Mauriège P,Cantin B,Dagenais GR,Moorjani S,Lupien PJ,Després JP

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To compare A1C and fasting glucose for the diagnosis of diabetes among U.S. adults. RESEARCH DESIGN AND METHODS:This study included 6,890 adults (> or =20 years of age) from the 1999-2006 National Health and Nutrition Examination Survey without a self-reported history of diabetes who had fasted > or =9 h. A1...

journal_title：Diabetes care

authors： Carson AP,Reynolds K,Fonseca VA,Muntner P

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Stress hyperglycemia has been associated with increased mortality in patients with myocardial infarction (MI). We examined the association between plasma glucose levels, circulating inflammatory markers, T-cell activation, and functional cardiac outcome in patients with first MI. RESEARCH DESIGN AND METHODS:...

journal_title：Diabetes care

authors： Marfella R,Siniscalchi M,Esposito K,Sellitto A,De Fanis U,Romano C,Portoghese M,Siciliano S,Nappo F,Sasso FC,Mininni N,Cacciapuoti F,Lucivero G,Giunta R,Verza M,Giugliano D

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:We aimed to update the epidemiology of type 1 and type 2 diabetic patients among the incident end-stage renal disease (ESRD) population in Australia and New Zealand (ANZ) and to determine whether outcome is worse for diabetic women, as described in the general population. RESEARCH DESIGNS AND METHODS:All res...

journal_title：Diabetes care

authors： Villar E,Chang SH,McDonald SP

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:An artificial pancreas (AP) that automatically regulates blood glucose would greatly improve the lives of individuals with diabetes. Such a device would prevent hypo- and hyperglycemia along with associated long- and short-term complications as well as ease some of the day-to-day burden of frequent blood gluc...

journal_title：Diabetes care

authors： Dassau E,Zisser H,Harvey RA,Percival MW,Grosman B,Bevier W,Atlas E,Miller S,Nimri R,Jovanovic L,Doyle FJ 3rd

更新日期：2013-04-01 00:00:00