Quality of care and outcomes in type 2 diabetic patients: a comparison between general practice and diabetes clinics.

Abstract:

OBJECTIVE:The role of general practice and diabetes clinics in the management of diabetes is still a matter of debate. Methodological flaws in previous studies may have led to inaccurate conclusions when comparing the care provided in these different settings. We compared the care provided to type 2 diabetic patients attending diabetes outpatient clinics (DOCs) or being treated by a general practitioner (GP) using appropriate statistical methods to adjust for patient case mix and physician-level clustering. RESEARCH DESIGN AND METHODS:We prospectively evaluated the process and intermediate outcome measures over 2 years in a sample of 3,437 patients recruited by 212 physicians with different specialties practicing in 125 DOCs and 103 general practice offices. Process measures included frequency of HbA(1c), lipids, microalbuminuria, and serum creatinine measurements and frequency of foot and eye examinations. Outcome measures included HbA(1c), blood pressure, and total and LDL cholesterol levels. RESULTS:Differences for most process measures were statistically significantly in favor of DOCs. The differences were more marked for patients who were always treated by the same physician within a DOC and if that physician had a specialty in diabetology. Less consistent differences in process measures were detected when patients followed by GPs were compared with those followed by physicians with a specialty other than diabetology. As for the outcomes considered, patients attending DOCs attained better total cholesterol levels, whereas no major differences emerged in terms of metabolic control and blood pressure levels between DOCs and GPs. Physicians' specialties were not independently related to patient outcomes. CONCLUSIONS:Being followed always by the same physician in a DOC, particularly if the physician had a specialty in diabetes, ensured better quality of care in terms of process measures. In the short term, care provided by DOCs was also associated with better intermediate outcome measures, such as total cholesterol levels.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

De Berardis G,Pellegrini F,Franciosi M,Belfiglio M,Di Nardo B,Greenfield S,Kaplan SH,Rossi MC,Sacco M,Tognoni G,Valentini M,Nicolucci A,QuED Study.

doi

10.2337/diacare.27.2.398

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

398-406

issue

2

eissn

0149-5992

issn

1935-5548

journal_volume

27

pub_type

杂志文章,多中心研究
  • Promises and Perils of Group Clinics for Young People Living With Diabetes: A Realist Review.

    abstract::Group clinics are becoming popular as a new care model in diabetes care. This evidence synthesis, using realist review methodology, examined the role of group clinics in meeting the complex needs of young people living with diabetes. Following Realist And Meta-narrative Evidence Synthesis-Evolving Standards (RAMESES) ...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:10.2337/dc18-2005

    authors: Papoutsi C,Colligan G,Hagell A,Hargreaves D,Marshall M,Vijayaraghavan S,Greenhalgh T,Finer S

    更新日期:2019-05-01 00:00:00

  • Insulin resistance, impaired early insulin response, and insulin propeptides as predictors of the development of type 2 diabetes: a population-based, 7-year follow-up study in 70-year-old men.

    abstract:OBJECTIVE:Defects in insulin secretion and insulin action are the major abnormalities in the development of type 2 diabetes. In middle-aged subjects, elevated plasma proinsulin has been found to predict type 2 diabetes. Therefore, our aim was to study the longitudinal relationships between baseline determinations of in...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.27.6.1433

    authors: Zethelius B,Hales CN,Lithell HO,Berne C

    更新日期:2004-06-01 00:00:00

  • Reduction of blood glucose variability in type 1 diabetic patients treated by pancreatic islet transplantation: interest of continuous glucose monitoring.

    abstract:OBJECTIVE:To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA). RESEARCH DESIGN AND METHODS:The CGMS enabled recording of subcutaneous g...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/diacare.25.12.2256

    authors: Kessler L,Passemard R,Oberholzer J,Benhamou PY,Bucher P,Toso C,Meyer P,Penfornis A,Badet L,Wolf P,Colin C,Morel P,Pinget M,GRAGIL Group.

    更新日期:2002-12-01 00:00:00

  • Predictors of Quality of Life and Other Patient-Reported Outcomes in the PANORAMA Multinational Study of People With Type 2 Diabetes.

    abstract:OBJECTIVE:PANORAMA, a nine-country cross-sectional type 2 diabetes study, investigated factors associated with quality of life (QoL), health status, and other patient-reported outcome measures (PROMs). RESEARCH DESIGN AND METHODS:Patients were randomly or consecutively selected from primary/secondary care. PROMs inclu...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/dc16-2655

    authors: Bradley C,Eschwège E,de Pablos-Velasco P,Parhofer KG,Simon D,Vandenberghe H,Gönder-Frederick L

    更新日期:2018-02-01 00:00:00

  • Body fatness and fat distribution as predictors of metabolic abnormalities and early carotid atherosclerosis.

    abstract:OBJECTIVE:To test the hypothesis that intra-abdominal fat plays a primary role over general adiposity for metabolic abnormalities and atherosclerosis. RESEARCH DESIGN AND METHODS:We cross-sectionally studied 849 Japanese men aged 50.3 +/- 8.5 years (range 20-78) with BMI 23.5 +/- 2.9 kg/m(2). Intimal-medial thickness ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.24.7.1248

    authors: Takami R,Takeda N,Hayashi M,Sasaki A,Kawachi S,Yoshino K,Takami K,Nakashima K,Akai A,Yamakita N,Yasuda K

    更新日期:2001-07-01 00:00:00

  • Effect of intensive glycemic control on microalbuminuria in type 2 diabetes. Veterans Affairs Cooperative Study on Glycemic Control and Complications in Type 2 Diabetes Feasibility Trial Investigators.

    abstract:OBJECTIVE:Microalbuminuria can reflect the progress of microvascular complications and may be predictive of macrovascular disease in type 2 diabetes. The effect of intensive glycemic control on microalbuminuria in patients in the U.S. who have had type 2 diabetes for several years has not previously been evaluated. RE...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.2337/diacare.23.10.1478

    authors: Levin SR,Coburn JW,Abraira C,Henderson WG,Colwell JA,Emanuele NV,Nuttall FQ,Sawin CT,Comstock JP,Silbert CK

    更新日期:2000-10-01 00:00:00

  • Myocardial Ischemic Burden and Differences in Prognosis Among Patients With and Without Diabetes: Results From the Multicenter International REFINE SPECT Registry.

    abstract:OBJECTIVE:Prevalence and prognostic impact of cardiovascular disease differ between patients with or without diabetes. We aimed to explore differences in the prevalence and prognosis of myocardial ischemia by automated quantification of total perfusion deficit (TPD) among patients with and without diabetes. RESEARCH D...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/dc19-1360

    authors: Han D,Rozanski A,Gransar H,Sharir T,Einstein AJ,Fish MB,Ruddy TD,Kaufmann PA,Sinusas AJ,Miller EJ,Bateman TM,Dorbala S,Di Carli M,Liang JX,Hu LH,Germano G,Dey D,Berman DS,Slomka PJ

    更新日期:2020-02-01 00:00:00

  • The use of medical hyperspectral technology to evaluate microcirculatory changes in diabetic foot ulcers and to predict clinical outcomes.

    abstract:OBJECTIVE:Foot ulceration is a serious complication of diabetes, and new techniques that can predict wound healing may prove very helpful. We tested the ability of medical hyperspectral technology (HT), a novel diagnostic scanning technique that can quantify tissue oxy- and deoxyhemoglobin to predict diabetic foot ulce...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc06-2209

    authors: Khaodhiar L,Dinh T,Schomacker KT,Panasyuk SV,Freeman JE,Lew R,Vo T,Panasyuk AA,Lima C,Giurini JM,Lyons TE,Veves A

    更新日期:2007-04-01 00:00:00

  • The importance of caloric restriction in the early improvements in insulin sensitivity after Roux-en-Y gastric bypass surgery.

    abstract:OBJECTIVE:Many of the metabolic benefits of Roux-en-Y gastric bypass (RYGB) occur before weight loss. In this study we investigated the influence of caloric restriction on the improvements in the metabolic responses that occur within the 1st week after RYGB. RESEARCH METHODS AND DESIGN: A mixed meal was administered to...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-2107

    authors: Isbell JM,Tamboli RA,Hansen EN,Saliba J,Dunn JP,Phillips SE,Marks-Shulman PA,Abumrad NN

    更新日期:2010-07-01 00:00:00

  • Leukocyte profiles differ between type 1 and type 2 diabetes and are associated with metabolic phenotypes: results from the German Diabetes Study (GDS).

    abstract:OBJECTIVE:Altered immune reactivity precedes and accompanies type 1 and type 2 diabetes. We hypothesized that the metabolic phenotype relates to the systemic cellular immune status. RESEARCH DESIGN AND METHODS:A total of 194 metabolically well-controlled patients with type 1 diabetes (n = 62, mean diabetes duration 1....

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc14-0316

    authors: Menart-Houtermans B,Rütter R,Nowotny B,Rosenbauer J,Koliaki C,Kahl S,Simon MC,Szendroedi J,Schloot NC,Roden M,German Diabetes Study Group.

    更新日期:2014-08-01 00:00:00

  • Sodium-Glucose Cotransporter 2 Inhibitors and the Risk of Below-Knee Amputation: A Multicenter Observational Study.

    abstract:OBJECTIVE:Reports of amputations associated with sodium-glucose cotransporter 2 (SGLT2) inhibitors have been inconsistent. We aimed to compare the risk of below-knee amputation with SGLT2 inhibitors versus dipeptidyl peptidase 4 (DPP-4) inhibitors among patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:This m...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc20-0267

    authors: Yu OHY,Dell'Aniello S,Shah BR,Brunetti VC,Daigle JM,Fralick M,Douros A,Hu N,Alessi-Severini S,Fisher A,Bugden SC,Ronksley PE,Filion KB,Ernst P,Lix LM,Canadian Network for Observational Drug Effect Studies (CNODES) Investiga

    更新日期:2020-10-01 00:00:00

  • Diabetes, glycemic control, and new-onset heart failure in patients with stable coronary artery disease: data from the heart and soul study.

    abstract:OBJECTIVE:Diabetes is a predictor of both coronary artery disease (CAD) and heart failure. It is unknown to what extent the association between diabetes and heart failure is influenced by other risk factors for heart failure. RESEARCH DESIGN AND METHODS:We evaluated the association of diabetes and A1C with incident he...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-0286

    authors: van Melle JP,Bot M,de Jonge P,de Boer RA,van Veldhuisen DJ,Whooley MA

    更新日期:2010-09-01 00:00:00

  • Impaired mitochondrial function and insulin resistance of skeletal muscle in mitochondrial diabetes.

    abstract:OBJECTIVE:Impaired muscular mitochondrial function is related to common insulin resistance in type 2 diabetes. Mitochondrial diseases frequently lead to diabetes, which is mostly attributed to defective beta-cell mitochondria and secretion. RESEARCH DESIGN AND METHODS:We assessed muscular mitochondrial function and li...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-2078

    authors: Szendroedi J,Schmid AI,Meyerspeer M,Cervin C,Kacerovsky M,Smekal G,Gräser-Lang S,Groop L,Roden M

    更新日期:2009-04-01 00:00:00

  • A health economic model to assess the long-term effects and cost-effectiveness of orlistat in obese type 2 diabetic patients.

    abstract:OBJECTIVES:Obesity is a common condition in type 2 diabetic patients. Treating obesity may enhance hypoglycemic treatment and contribute to the reduction of long-term microvascular and macrovascular complications. Orlistat reduces cardiovascular risk factors in obese type 2 diabetic patients. The objectives of this stu...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.25.2.303

    authors: Lamotte M,Annemans L,Lefever A,Nechelput M,Masure J

    更新日期:2002-02-01 00:00:00

  • Normal glucose values are associated with a lower risk of mortality in hospitalized patients.

    abstract:OBJECTIVE:Hyperglycemia is a common condition in hospitalized patients. The aim of this study was to investigate the relationships between glycemia upon admission and mortality in a heterogeneous group of adult patients. RESEARCH DESIGN AND METHODS:The 3-year records released from a general hospital were associated wi...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc08-0672

    authors: Bruno A,Gregori D,Caropreso A,Lazzarato F,Petrinco M,Pagano E

    更新日期:2008-11-01 00:00:00

  • Atherosclerotic vascular disease and its risk factors in non-insulin-dependent diabetic and nondiabetic subjects in Finland.

    abstract::A cross-sectional study on the prevalence of atherosclerotic vascular disease (ASVD) and its risk factors in non-insulin-dependent diabetic and nondiabetic subjects was carried out from 1982 to 1984 in East Finland (Kuopio) and West Finland (Turku), two areas known to differ markedly in prevalence of ASVD in the nondi...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.11.6.449

    authors: Laakso M,Rönnemaa T,Pyörälä K,Kallio V,Puukka P,Penttilä I

    更新日期:1988-06-01 00:00:00

  • Intact proinsulin and beta-cell function in lean and obese subjects with and without type 2 diabetes.

    abstract:OBJECTIVE:Type 2 diabetes is a heterogeneous disease in which both beta-cell dysfunction and insulin resistance are pathogenetic factors. Disproportionate hyperproinsulinemia (elevated proinsulin/insulin) is another abnormality in type 2 diabetes whose mechanism is unknown. Increased demand due to obesity and/or insuli...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.22.4.609

    authors: Røder ME,Dinesen B,Hartling SG,Houssa P,Vestergaard H,Sodoyez-Goffaux F,Binder C

    更新日期:1999-04-01 00:00:00

  • The Prognostic Significance of Diabetes and Microvascular Complications in Patients With Heart Failure With Preserved Ejection Fraction.

    abstract:OBJECTIVE:This study examined the prognostic significance of diabetes and microvascular complications in patients with heart failure with preserved ejection fraction (HFpEF). RESEARCH DESIGN AND METHODS:This analysis included 3,385 patients (mean age 69 ± 9.6 years; 49% male; 89% white) with HFpEF from the Treatment o...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2337/dc17-0755

    authors: Sandesara PB,O'Neal WT,Kelli HM,Samman-Tahhan A,Hammadah M,Quyyumi AA,Sperling LS

    更新日期:2018-01-01 00:00:00

  • A Multidisciplinary Evaluation of a Virtually Supervised Home-Based High-Intensity Interval Training Intervention in People With Type 1 Diabetes.

    abstract:OBJECTIVE:Adopt a multidisciplinary approach to evaluate a virtually supervised home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes. RESEARCH DESIGN AND METHODS:Eleven individuals with type 1 diabetes (seven women; age 30 ± 3 years; [Formula: see text] 2.5 ± 0.2 L/min; du...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-0871

    authors: Scott SN,Shepherd SO,Andrews RC,Narendran P,Purewal TS,Kinnafick F,Cuthbertson DJ,Atkinson-Goulding S,Noon T,Wagenmakers AJM,Cocks M

    更新日期:2019-12-01 00:00:00

  • Cellular ions in NIDDM: relation of calcium to hyperglycemia and cardiac mass.

    abstract:OBJECTIVE:To investigate the role of hyperglycemia in mediating the clinical association of NIDDM with hypertension and left ventricular dysfunction and hypertrophy. RESEARCH DESIGN AND METHODS:Since hyperglycemia elevates cytosolic free calcium (Cai) both in myocardial and vascular smooth muscle cells, we utilized nu...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.19.12.1393

    authors: Barbagallo M,Gupta RK,Resnick LM

    更新日期:1996-12-01 00:00:00

  • Insomnia with objective short sleep duration is associated with type 2 diabetes: A population-based study.

    abstract:OBJECTIVE:We examined the joint effects of insomnia and objective short sleep duration, the combination of which is associated with higher morbidity, on diabetes risk. RESEARCH DESIGN AND METHODS:A total of 1,741 men and women randomly selected from Central Pennsylvania were studied in the sleep laboratory. Insomnia w...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-0284

    authors: Vgontzas AN,Liao D,Pejovic S,Calhoun S,Karataraki M,Bixler EO

    更新日期:2009-11-01 00:00:00

  • Effect of protein ingestion on the glucose and insulin response to a standardized oral glucose load.

    abstract::Type II diabetic subjects were given 50 g protein, 50 g glucose, or 50 g glucose with 50 g protein as a single meal in random sequence. The plasma glucose and insulin response was determined over the subsequent 5 h. The plasma glucose area above the baseline following a glucose meal was reduced 34% when protein was gi...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.7.5.465

    authors: Nuttall FQ,Mooradian AD,Gannon MC,Billington C,Krezowski P

    更新日期:1984-09-01 00:00:00

  • Increased cardiometabolic risk factors and inflammation in adipose tissue in obese subjects classified as metabolically healthy.

    abstract:OBJECTIVE:It has been suggested that individuals with the condition known as metabolically healthy obesity (MHO) may not have the same increased risk for the development of metabolic abnormalities as their non-metabolically healthy counterparts. However, the validity of this concept has recently been challenged, since ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc14-0937

    authors: Gómez-Ambrosi J,Catalán V,Rodríguez A,Andrada P,Ramírez B,Ibáñez P,Vila N,Romero S,Margall MA,Gil MJ,Moncada R,Valentí V,Silva C,Salvador J,Frühbeck G

    更新日期:2014-10-01 00:00:00

  • Dietary fat intake predicts 1-year change in body fat in adolescent girls with type 1 diabetes.

    abstract:OBJECTIVE:The purpose of this study was to determine whether objectively measured physical activity and dietary macronutrient intake differentially predict body fat in adolescent girls with type 1 diabetes and control girls. RESEARCH DESIGN AND METHODS:This study comprised 23 girls (12-19 years) with type 1 diabetes a...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc05-2318

    authors: Särnblad S,Ekelund U,Aman J

    更新日期:2006-06-01 00:00:00

  • Predictive effects of urinary liver-type fatty acid-binding protein for deteriorating renal function and incidence of cardiovascular disease in type 2 diabetic patients without advanced nephropathy.

    abstract:OBJECTIVE:To improve prognosis, it is important to predict the incidence of renal failure and cardiovascular disease in type 2 diabetic patients before the progression to advanced nephropathy. We investigated the predictive effects of urinary liver-type fatty acid-binding protein (L-FABP), which is associated with rena...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-1298

    authors: Araki S,Haneda M,Koya D,Sugaya T,Isshiki K,Kume S,Kashiwagi A,Uzu T,Maegawa H

    更新日期:2013-05-01 00:00:00

  • Long-acting insulin analogs.

    abstract::Once daily injection of existing intermediate/long-acting insulin preparations does not provide a 24-h basal insulinemia in most patients. High variability, pronounced insulin peaks, and (as a result) a high risk of nocturnal hypoglycemia only poorly simulate normal physiology. One principle to prolong insulin action ...

    journal_title:Diabetes care

    pub_type: 杂志文章,评审

    doi:

    authors: Rosskamp RH,Park G

    更新日期:1999-03-01 00:00:00

  • Hypocalcemia, hypomagnesemia, and transient hypoparathyroidism during therapy with potassium phosphate in diabetic ketoacidosis.

    abstract::The effects of intravenous administration of potassium phosphate in the treatment of diabetic ketoacidosis were studied in nine children, ages 9 9/12 to 17 10/12 yr. During phosphate infusion (20--40 meq/L of fluid), all children maintained normal serum concentrations of phosphorus. Transient hypocalcemia occurred in ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.2.3.265

    authors: Zipf WB,Bacon GE,Spencer ML,Kelch RP,Hopwood NJ,Hawker CD

    更新日期:1979-05-01 00:00:00

  • Dual hormonal replacement with insulin and recombinant human insulin-like growth factor I in IDDM. Effects on glycemic control, IGF-I levels, and safety profile.

    abstract:OBJECTIVE:To examine if dual replacement with insulin and rhIGF-I, recombinant human insulin-like growth factor I (rhIGF-I) may be safe and result in improved metabolic control and reduced insulin usage. RESEARCH DESIGN AND METHODS:Forty-three patients with IDDM were randomized to receive a daily injection of rhIGF-I ...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.2337/diacare.20.3.374

    authors: Quattrin T,Thrailkill K,Baker L,Litton J,Dwigun K,Rearson M,Poppenheimer M,Giltinan D,Gesundheit N,Martha P Jr

    更新日期:1997-03-01 00:00:00

  • Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients.

    abstract:OBJECTIVE:The safety of dendritic cells to selectively suppress autoimmunity, especially in type 1 diabetes, has never been ascertained. We investigated the safety of autologous dendritic cells, stabilized into an immunosuppressive state, in established adult type 1 diabetic patients. RESEARCH DESIGN AND METHODS:A ran...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc11-0472

    authors: Giannoukakis N,Phillips B,Finegold D,Harnaha J,Trucco M

    更新日期:2011-09-01 00:00:00

  • Eating fish and risk of type 2 diabetes: A population-based, prospective follow-up study.

    abstract:OBJECTIVE:To investigate the relation between total fish, type of fish (lean and fatty), and eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) intake and risk of type 2 diabetes in a population-based cohort. RESEARCH DESIGN AND METHODS:The analysis included 4,472 Dutch participants aged >or=55 years without d...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc09-1042

    authors: van Woudenbergh GJ,van Ballegooijen AJ,Kuijsten A,Sijbrands EJ,van Rooij FJ,Geleijnse JM,Hofman A,Witteman JC,Feskens EJ

    更新日期:2009-11-01 00:00:00